Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition

American Journal of Nephrology

Volumn 28, Issue 1, 2007, Pages 143-151

  Liu, Bi Cheng ^a   Li, Min Xia ^a   Zhang, Jian Dong ^a   Liu, Xiao Cong ^a   Zhang, Xiao Liang ^a   Phillips, Aled O ^b  

^a SOUTHEAST UNIVERSITY   (China)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Connective tissue growth factor; Epithelial to mesenchymal transition; Integrin linked kinase; RNA interference

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; INTEGRIN LINKED KINASE; MESSENGER RNA; SMALL INTERFERING RNA; UVOMORULIN;

ARTICLE; CELL LINE; CELL STIMULATION; CELL TRANSFORMATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME INHIBITION; EPITHELIAL CELL TO MESENCHYMAL TRANSITION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; KIDNEY EPITHELIUM; KIDNEY INTERSTITIUM; KIDNEY PROXIMAL TUBULE; MESENCHYME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ACTINS; CADHERINS; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY TUBULES, PROXIMAL; MESODERM; NEPHRITIS, INTERSTITIAL; PLASMIDS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 36248961701     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110019     Document Type: Article

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