An in vitro investigation of endocrine disrupting effects of trichothecenes deoxynivalenol (DON), T-2 and HT-2 toxins

Toxicology Letters

Volumn 214, Issue 3, 2012, Pages 268-278

  Ndossi, D G ^a,b   Frizzell, C ^c   Tremoen, N H ^a   Faeste C K ^d   Verhaegen, S ^a   Dahl, E ^a   Eriksen, G S ^d   Sorlie M ^a   Connolly, L ^c   Ropstad, E ^a  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b SOKOINE UNIVERSITY OF AGRICULTURE   (Tanzania)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d NORWEGIAN VETERINARY INSTITUTE   (Norway)

Author keywords

Endocrine disruptor; Gene expression; H295R; Reporter gene assay; Steroidogenesis

Indexed keywords

ANDROGEN; ESTROGEN; GESTAGEN; GLUCOCORTICOID; HT 2 TOXIN; T 2 TOXIN; VOMITOXIN;

17BETA HYDROXYSTEROID DEHYDROGENASE 1 GENE; 17BETA HYDROXYSTEROID DEHYDROGENASE 4 GENE; ACTB GENE; ALDOSTERONE SYNTHETASE GENE; AROMATASE GENE; ARTICLE; ATP5B GENE; B2M GENE; BETA HYDROXYSTEROID DEHYDROGENASE 2 GENE; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; CYTOCHROME P450 11A GENE; CYTOCHROME P450 11B1 GENE; CYTOCHROME P450 17 GENE; CYTOCHROME P450 1A1 GENE; CYTOCHROME P450 21 GENE; CYTOTOXICITY; DOWN REGULATION; EPOXIDE HYDROLASE GENE; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; HYDROXY METHYLGLUTARYL COA REDUCTASE GENE; IN VITRO STUDY; MELANOCORTIN 2 RECEPTOR GENE; NUCLEAR RECEPTOR 0B1 GENE; NUCLEAR RECEPTOR 5A1 GENE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; STEROIDOGENESIS; STEROIDOGENIC ACUTE REGULATORY GENE; UPREGULATION;

ADRENOCORTICAL CARCINOMA; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; ENDOCRINE DISRUPTORS; FEMALE; GENE EXPRESSION REGULATION; GENES, REPORTER; HORMONE ANTAGONISTS; HORMONES; HUMANS; LUCIFERASES; MAMMARY GLANDS, HUMAN; RECEPTORS, STEROID; T-2 TOXIN; TRANSFECTION; TRICHOTHECENES;

FUSARIUM;

EID: 84867235958     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.09.005     Document Type: Article

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