Evidence for androgen receptor gene expression and growth inhibitory effect of dihydrotestosterone on human adrenocortical cells

Journal of Endocrinology

Volumn 159, Issue 3, 1998, Pages 373-380

  Rossi, R ^a   Zatelli, M C ^a   Valentini, A ^a   Cavazzini, P ^b   Fallo, F ^c   Del Senno, L ^d   Uberti, E C Degli ^a,d  

^a Section of Endocrinology   (Italy)

^b Istituto di Anatomia Patologica   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; CYPROTERONE ACETATE; HYDROXYFLUTAMIDE;

ADRENAL CORTEX CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GROWTH INHIBITION; HORMONE ACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENAL CORTEX; ANDROGEN ANTAGONISTS; CELL DIVISION; CELLS, CULTURED; CYPROTERONE ACETATE; DIHYDROTESTOSTERONE; FEMALE; FLUTAMIDE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 0032442247     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1590373     Document Type: Article

References (24)

1. Bentvelsen FM, McPhaul MJ, Wilson CM, Wilson JD & George FW 1996 Regulation of immunoreactive androgen receptor in the adrenal gland of the adult rat. Endocrinology 137 2659-2663.
2. Berger FG & Watson G 1989 Androgen regulated gene expression. Annual Review of Physiology 51 51-65.
3. Calandra V, Purvis K, Naess O, Attramadal A, Djoseland O & Hansson V 1978 Androgen receptor in the rat adrenal gland. Journal of Steroid Biochemistry 9 1009-1015.
4. Faber PW, Van Rooij HCJ, Van der Korput HA, Baarends WM, Brinkmann AO, Grootegoed JA & Trapman J 1991 Characterization of the human androgen receptor transcription unit. Journal of Biological Chemistry 266 10743-10749.
5. Hirst JJ, West NB, Brenner RM & Novy MJ 1992 Steroid hormone receptors in the adrenal glands of fetal and adult rhesus monkeys. Journal of Clinical Endocrinology and Metabolism 75 308-314.
6. Husmann DA, Wilson CM, McPhaul MJ, Tilley WD & Wilson JD 1990 Antipeptide antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate. Endocrinology 126 2359-2368.
7. Jenster G, van der Corput JA, Trapman J & Brinkmann AO 1992 Functional domains of the human androgen receptor. Journal of Steroid Biochemistry and Molecular Biology 41 671-675.
8. Kasser A, Kozlowski JM & Lee C 1995 Role of basic fibroblast growth factor in autocrine regulation of LNCaP proliferation induced by dihydrotestosterone. Program of the 77th Annual Meeting of The Endocrine Society, Washington DC, p 272 (Abstract 1-639).
9. Kemppainen JA, Lane MV, Sar M & Wilson EM 1992 Androgen receptor phosphorylation, turnover, nuclear transport and transcriptional activation. Specificity for steroids and antihormones. Journal of Biological Chemistry 267 968-974.
10. Kim IY, Kim JH, Zelner DJ, Ahn HJ, Sensibar JA & Lee C 1996 Transforming growth factor β1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP. Endocrinology 137 991-999.
11. Lubahn DB, Josef DR, Sullivan PM, Willard HF, French FS & Wilson EM 1988 Cloning of human androgen receptor complementary DNA and localization to the X chromosome. Science 240 327-330.
12. Mooradian AD, Morley JE & Korenman SG 1987 Biological actions of androgens. Endocrine Revue 8 1-28.
13. Rifka SM, Cutler JB, Sauer MA & Loriaux DL 1978 Rat adrenal androgen receptor: a possible mediator of androgen-induced decrease in rat adrenal weight. Endocrinology 103 1103-1110.
14. Rossi R, Franceschetti P, Maestri I, Magri E, Cavazzini L, degli Uberti EC & del Senno L 1996a Evidence for androgen receptor gene expression in human thyroid cells and tumors. Journal of Endocrinology 148 77-85.
15. Rossi R, Zatelli MC, Franceschetti P, Maestri I, Magri E, Aguiari G, Cavazzini P, degli Uberti EC & del Senno L 19966 Inhibitory effect of dihydrotestosterone on human thyroid cell growth. Journal of Endocrinology 151 185-194.
16. Ruizeveld de Winter JA, Trapman J, Vermey M, Mulder E, Zegers ND & Van der Kwast TH 1991 Androgen receptor expression in human tissues: an immunohistochemical study. Journal of Histochemistry and Cytochemistry 39 927-936.
17. Sambrook J, Fritish ET, Maniatis F 1989 Molecular Cloning, A Laboratory Manual. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.
18. Sar M, Lubahn DB, French FS & Wilson EM 1990 Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocrinology 127 3180-3186.
19. Schuurmans AL, Bolt J, Voorhorst MM, Blankenstein RA & Mulder E 1988 Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids. International Journal of Cancer 42 917-922.
20. Szelei J, Jimenez J, Soto AM, Luizzi MF & Sonnenschein C 1997 Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor. Endocrinology 138 1406-1412.
21. Toscano V, Caiola S, Maroder M, Adamo MV, Argiolas L, Familiari A & Familiari G 1990 Effects of dihydrotestosterone treatment on adrenal gland function and morphology in adult female guinea-pigs. Journal of Steroid Biochemistry 36 89-97.
22. 3H-thymidine incorporation and c-myc, but not thyroglobulin ribonucleic acid levels in human thyroid follicular cells in vitro. Journal of Clinical Endocrinology and Metabolism 72 1364-1371.
23. Wolf DA, Schulz P & Fittler F 1991 Synthetic androgens suppress the transformed phenotype in the human prostate carcinoma cell line LNCaP. British Journal of Cancer 64 47-53.
24. Wong CI, Zhou ZX, Sar M & Wilson EM 1993 Steroid requirement for androgen receptor dimerization and DNA binding. Journal of Biological Chemistry 268 19004-19012.