In vitro sustained release of human immunoglobulin G from biodegradable microspheres

Industrial and Engineering Chemistry Research

Volumn 40, Issue 3, 2001, Pages 933-948

  Wong, H M ^a   Wang, J J ^a   Wang, C H ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN G; MICROSPHERE; POLYGLACTIN; POLYLACTIDE;

ARTICLE; CONFOCAL LASER MICROSCOPY; DRUG FORMULATION; DRUG SOLUBILITY; ENCAPSULATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE;

EID: 0035143865     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie0006256     Document Type: Article

References (50)

1. Polymers for the sustained release of proteins and other macromolecules
2. Thirty years of supplying the missing link
3. Monthly immunoglobulin therapy improved relapsing-remitting multiple sclerosis
4. Elevated peripheral blood natural killer cells are effectively downregulated by Immunoglobulin G infusion in women with recurrent spontaneous abortions
5. Lactic/glycolic acid polymers
6. Protein delivery from biodegradable microspheres
7. Microcapsules and microspheres for embolization and chemoembolization
8. Nanoparticle drug delivery system for restenosis
9. The uptake and translocation of latex nanoparticles and microspheres after oral administration to rats
10. Continuous release of protein from biodegradable microspheres and in vivo evaluation of their potential as a vaccine adjuvant
11. Microencapsulation using poly(L-lactic acid). IV: Release properties of microcapsules containing phenobarbitone
12. Biodegradable poly(lactic acid) poly(lactide-co-glycolide) microcapsules: Problems associated with preparative techniques and release properties
13. Lidocaine loaded biodegradable nanospheres: II. Modeling of drug release
14. Protein encapsulation within PEG-coated nanospheres: I. Physicochemical characterization
15. A model of dissolution-controlled, diffusional drug release from nonswellable polymeric microspheres
16. Protein delivery from poly(lactic-co-glycolic acid) biodegradable microspheres: Release kinetics and stability issues
17. A new preparation method for protein loaded poly(D,L-lactic-co-glycolic acid) microspheres and protein release mechanism study
18. Biodegradable microspheres as controlled-release tetanus toxoid delivery systems
19. A comparison of alternative methods for the determination of the levels of proteins entrapped in poly(lactide-co-glycolide) microparticles
20. Stabilization of tetanus toxoid in poly(DL-lactic-co-glycolic acid) microspheres for the controlled release of antigen
21. A new strategy to determine the actual protein content of poly(lactide-co-glycolide) microspheres
22. Characterization of biodegradable poly(D,L-lactide-co-glycolide) polymers and microspheres
23. Controlled release of human immunoglobulin G. 1. Release kinetics studies
24. Calculation of the dimensions of drug-polymer devices based on diffusion parameters
25. Determinants of release rate from tetanus vaccine from polyester microspheres
26. A diffusion-controlled model for wet-casting membrane formation
27. A poly(D,L-lactide-co-glycolide) microsphere depot system for delivery of haloperidol
28. Optimization of preparative conditions for poly-DL-lactide-poly(ethylene glycol) microspheres with entrapped Vibrio Cholera antigens
29. The stability of recombinant human growth hormone in poly(lactic-co-glycolic acid) (PLGA) microspheres
30. Protein-loaded poly(DL-lactic-co-glycolide) microspheres for oral administration: Formulation, structural and release characteristics
31. Preparation and characterization of 5-fluorouracil-loaded microparticles & biodegradable anticancer drug carriers
32. Stability and release of bovine serum albumin encapsulated within poly(DL-lactic-co-glycolide) microparticles
33. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery
34. Release of human serum albumin from poly(lactide-co-glycolide) microspheres
35. Mechanisms of polymer degradation and elimination
36. Adsorption determines in vitro protein release rate from biodegradable microspheres: Quantitative analysis of surface area during degradation
37. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres
38. Influence of formulation methods on the in vivo controlled release of protein from poly(ester) microparticles
39. Microparticles of poly(D,L-lactide-co-glycolic acid)/poly(ethylene glycol) blends for controlled drug delivery
40. Thymopentin loaded microsphere preparation by w/o/w emulsion technique: In vitro/ex vivo evaluation
41. Stability of proteins and their delivery from biodegradable polymer microspheres
42. Delivery of proteins from a controlled release injectable implant
43. Microstructural models for diffusive transport in porous polymers
44. A theoretical model of erosion and macromolecular drug release from biodegrading microspheres
45. Macromolecules released from polymers: Diffusion into unstirred fluids
46. Dissolution-controlled transport from dispersed matrices
47. Modeling of sustained release of water-soluble drugs from porous, hydrophobic polymers