In vitro degradation and release profiles of poly-DL-lactide-poly(ethylene glycol) microspheres with entrapped proteins

Journal of Applied Polymer Science

Volumn 78, Issue 1, 2000, Pages 140-148

  Li, Xiaohong ^a   Deng, Xianmo ^a   Yuan, Minglong ^a   Xiong, Chengdong ^a   Huang, Zhitang ^b   Zhang, Yanhua ^c   Jia, Wenxiang ^c  

^a CHENGDU INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b INSTITUTE OF CHEMISTRY   (Taiwan)

^c SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPOSITION EFFECTS; DEGRADATION; EVAPORATION; INITIATORS (CHEMICAL); MOLECULAR WEIGHT DISTRIBUTION; MORPHOLOGY; PH EFFECTS; POLYESTERS; POLYETHYLENE GLYCOLS; PROTEINS; RATE CONSTANTS; RING OPENING POLYMERIZATION;

BUFFER SOLUTION; MICROSPHERES; POLYLACTIDE; SCANNING ELECTRON MICROGRAPHY; STANNOUS CHLORIDE; SURFACE EROSION;

ORGANIC POLYMERS;

EID: 0034300647     PISSN: 00218995     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4628(20001003)78:1<140::AID-APP180>3.0.CO;2-P     Document Type: Article

References (18)

1. Hudson, A. J.; Lewis, K. J.; Rao, M. V. Int J Pharm 1996, 136, 23.
2. Yamakawa, I.; Tsushima, Y.; Machida, R. J Pharm Sci 1992, 81, 808.
3. Burns, R. A; Vitale, J.; Sanders, L. M. J Microencapsulation 1990, 7, 397.
4. Slusky, V.; Tamada, J. A.; Klibanov, A. M.; Langer, R. Proc Natl Acad Sci USA 1991, 88, 9377.
5. Kenley, R. A.; Lee, M. O.; Mahoney, T. R.; Sanders, L. H. Macromolecules 1987, 20, 2398.
6. Deng, X. M.; Xiong, C. D.; Cheng, L. M. J Polym Sci Polym Lett 1990, 28, 411.
7. Wang, D. G.; Zheng, H.; Hu, Y. J.; Qiu, S. H. Beijing Shengwu Yixue Gongcheng (in Chinese) 1995, 14, 173.
8. Li, X. H.; Yuan, M. L.; Xiong, C. D.; Deng, X. M.; Huang, Z. T. Acta Polym Sin (in Chinese), 1998, to appear.
9. Li, X. W.; Xiao, J.; Deng, X. M. J Appl Polym Sci 1997, 66, 583.
10. Deng, X. M.; Li, X. H.; Yuan, M. L.; Xiong, C. D.; Huang, Z. T. J Controlled Release, to appear.
11. Zhu, K. J.; Shen, Z. R.; Wu, L. T.; Yang, S. L. J Appl Polym Sci 1991, 43, 2099.
12. Vert, M.; Li, S.; Garreau, H. J Controlled Release 1991, 16, 151.
13. Bradford, M. Anal Biochem 1976, 72, 248.
14. Eldridge, J. H.; Hammond, C. J.; Meulbroek, J. A. J Controlled Release 1990, 11, 205.
15. Holland, S. J.; Tighe, B. J.; Gould, P. L. J Controlled Release 1986, 4, 155.
16. Sanders, L. M.; Kent, T. J.; McRae, G. I. J Pharm Sci 1984, 73, 1294.
17. Uchida, T.; Goto, S.; Foster, T. P. J Pharm Pharmacol 1994, 47, 556.
18. Sorensen, R. A.; Peppas, N. A. Proc IUPAC Membr Symp Macromol 1979, 26, 1108.