TLR4-mediated IL-12 production enhances IFN-γ and IL-1β production, which inhibits TGF-β production and promotes antibody-induced joint inflammation

Arthritis Research and Therapy

Volumn 14, Issue 5, 2012, Pages

  Kim, Hye S ^a   Chung, Doo H ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; STAT4 PROTEIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA; TLR4 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HISTOPATHOLOGY; MACROPHAGE; MAST CELL; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; FEMALE; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS; DISEASE MODELS, ANIMAL; FEMALE; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA;

EID: 84866933496     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4048     Document Type: Article

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