Dynamic interactions between T cells and dendritic cells and their derived cytokines/chemokines in the rheumatoid synovium

Arthritis Research and Therapy

Volumn 10, Issue SUPPL. 1, 2008, Pages

  Miossec, Pierre ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; ANTIINFLAMMATORY AGENT; CHEMOKINE; CHEMOKINE RECEPTOR ANTAGONIST; CYTOKINE; CYTOKINE RECEPTOR ANTAGONIST; IMMUNOMODULATING AGENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OKT 4; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL INTERACTION; CELL MATURATION; CELLULAR IMMUNITY; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE ACTIVITY; DISEASE CONTROL; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; EFFECTOR CELL; GERMINAL CENTER; HELPER CELL; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INFLAMMATORY CELL; INNATE IMMUNITY; LEUKOCYTE MIGRATION; LYMPHOCYTE DEPLETION; NONHUMAN; PROTEIN FAMILY; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; REVIEW; RHEUMATOID ARTHRITIS; SYNOVITIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; UPREGULATION; CELL COMMUNICATION; CYTOLOGY; IMMUNOLOGY; SYNOVIUM;

ARTHRITIS, RHEUMATOID; CELL COMMUNICATION; CHEMOKINES; CYTOKINES; DENDRITIC CELLS; HUMANS; SYNOVIAL MEMBRANE; T-LYMPHOCYTES;

EID: 54049142102     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2413     Document Type: Review

References (35)

1. Firestein GS Evolving concepts of rheumatoid arthritis Nature 2003, 423:356-361. 10.1038/nature01661
2. Feldmann M Brennan FM Foxwell BM Taylor PC Williams RO Maini RN Anti-TNF therapy: Where have we got to in 2005? J Autoimmun 2005, 25(suppl):26-28. 10.1016/j.jaut.2005.09.006
3. Steinman RM Banchereau J Taking dendritic cells into medicine Nature 2007, 449:419-426. 10.1038/nature06175
4. Lutzky V Hannawi S Thomas R Cells of the synovium in rheumatoid arthritis. Dendritic cells Arthritis Res Ther 2007, 9;219. 10.1186/ar2200
5. Firestein GS Zvaifler NJ How important are T cells in chronic rheumatoid synovitis? Arthritis Rheum 1990, 33:768-773. 10.1002/art.1780330602
6. Miossec P Chomarat P Dechanet J Moreau JF Roux JP Delmas P Banchereau J Interleukin-4 inhibits bone resorption through an effect on osteoclasts and proinflammatory cytokines in an ex vivo model of bone resorption in rheumatoid arthritis Arthritis Rheum 1994, 37:1715-1722. 10.1002/ art.1780371202
7. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha J Exp Med 1996, 184:695-706. 10.1084/jem.184.2.695
8. Miossec P Naviliat M Dupuy d'Angeac A Sany J Banchereau J Low levels of interleukin-4 and high levels of transforming growth factor beta in rheumatoid synovitis Arthritis Rheum 1990, 33:1180-1187. 10.1002/ art.1780331112
9. Lebre MC Jongbloed SL Tas SW Smeets TJ McInnes IB Tak PP Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles Am J Pathol 2008, 172:940-950. 10.2353/ ajpath.2008.070703
10. Page G Lebecque S Miossec P Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: Correlation with selective chemokine expression in rheumatoid synovium J Immunol 2002, 168:5333-5341.
11. Roelofs MF Joosten LA Abdollahi-Roodsaz S van Lieshout AW Sprong T Hoogen van den FH Berg van den WB Radstake TR The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells Arthritis Rheum 2005, 52:2313-2322. 10.1002/art.21278
12. Bennett L Palucka AK Arce E Cantrell V Borvak J Banchereau J Pascual V Interferon and granulopoiesis signatures in systemic lupus erythematosus blood J Exp Med 2003, 197:711-723. 10.1084/jem.20021553
13. Pouw Kraan van der TC Wijbrandts CA van Baarsen LG Voskuyl AE Rustenburg F Baggen JM Ibrahim SM Fero M Dijkmans BA Tak PP Verweij CL Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: Assignment of a type I interferon signature in a subpopulation of patients Ann Rheum Dis 2007, 66:1008-1014. 10.1136/ard.2006.063412
14. Trinchieri G Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat Rev Immunol 2003, 3:133-146. 10.1038/nri1001
15. Kawashima M Miossec P Heterogeneity of response of rheumatoid synovium cell subsets to interleukin-18 in relation to differential interleukin-18 receptor expression Arthritis Rheum 2003, 48:631-637. 10.1002/art.10825
16. McKenzie BS Kastelein RA Cua DJ Understanding the IL-23-IL-17 immune pathway Trends Immunol 2006, 27:17-23. 10.1016/j.it.2005.10.003
17. Brentano F Ospelt C Stanczyk J Gay RE Gay S Kyburz D Abundant expression of the IL-23 subunit p19, but low levels of bioactive IL-23 in the rheumatoid synovium Ann Rheum Dis 2008.
18. Miossec P Interleukin-17 in fashion, at last: Ten years after its description, its cellular source has been identified Arthritis Rheum 2007, 56:2111-2115. 10.1002/art.22733
19. Bettelli E Korn T Kuchroo VK Th17: The third member of the effector T cell trilogy Curr Opin Immunol 2007, 19:652-657. 10.1016/ j.coi.2007.07.020
20. + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Nat Immunol 2005, 6:1123-1132. 10.1038/ni1254
21. Park H Li Z Yang XO Chang SH Nurieva R Wang YH Hood L Zhu Z Tian Q Dong C A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Nat Immunol 2005, 6:1133-1141. 10.1038/ni1261
22. Chabaud M Durand JM Buchs N Fossiez F Page G Frappart L Miossec P Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium Arthritis Rheum 1999, 42:963-970. 10.1002/ 1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E
23. Aarvak T Chabaud M Miossec P Natvig JB IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells J Immunol 1999, 162:1246-1251.
24. Page G Sattler A Kersten S Thiel A Radbruch A Miossec P Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression Am J Pathol 2004, 164:409-417.
25. Chabaud M Aarvak T Garnero P Natvig JB Miossec P Potential contribution of IL-17-producing Th(1) cells to defective repair activity in joint inflammation: Partial correction with Th(2)-promoting conditions Cytokine 2001, 13:113-118. 10.1006/cyto.2000.0811
26. Nadkarni S Mauri C Ehrenstein MR Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta J Exp Med 2007, 204:33-39. 10.1084/jem.20061531
27. Haringman JJ Smeets TJ Reinders-Blankert P Tak PP Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis Ann Rheum Dis 2006, 65:294-300. 10.1136/ard.2005.037176
28. Dieu MC Vanbervliet B Vicari A Bridon JM Oldham E Aït-Yahia S Brière F Zlotnik A Lebecque S Caux C Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites J Exp Med 1998, 188:373-386. 10.1084/ jem.188.2.373
29. Chabaud M Page G Miossec P Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: Regulation by soluble receptors and Th2 cytokines J Immunol 2001, 167:6015-6020.
30. Hirota K Yoshitomi H Hashimoto M Maeda S Teradaira S Sugimoto N Yamaguchi T Nomura T Ito H Nakamura T Sakaguchi N Sakaguchi S Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model J Exp Med 2007, 204:2803-2812. 10.1084/jem.20071397
31. Hardtke S Ohl L Forster R Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help Blood 2005, 106:1924-1931. 10.1182/blood-2004-11-4494
32. Page G Miossec P Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression J Pathol 2004, 204:28-38. 10.1002/path.1607
33. Vos K Thurlings RM Wijbrandts CA van Schaardenburg D Gerlag DM Tak PP Early effects of rituximab on the synovial cell infiltrate in patients with rheumatoid arthritis Arthritis Rheum 2007, 56:772-778. 10.1002/ art.22400
34. Radbruch A Muehlinghaus G Luger EO Inamine A Smith KG Dorner T Hiepe F Competence and competition: The challenge of becoming a long-lived plasma cell Nat Rev Immunol 2006, 6:741-750. 10.1038/nri1886
35. Kremer JM Westhovens R Leon M Di Giorgio E Alten R Steinfeld S Russell A Dougados M Emery P Nuamah IF Williams GR Becker JC Hagerty DT Moreland LW Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig N Engl J Med 2003, 349:1907-1915. 10.1056/NEJMoa035075