Multiplexed activity-based protein profiling of the human pathogen Aspergillus fumigatus reveals large functional changes upon exposure to human serum

Journal of Biological Chemistry

Volumn 287, Issue 40, 2012, Pages 33447-33459

  Wiedner, Susan D ^a   Burnum, Kristin E ^a   Pederson, LeeAnna M ^a   Anderson, Lindsey N ^a   Fortuin, Suereta ^a   Chauvigné Hines, Lacie M ^a   Shukla, Anil K ^a   Ansong, Charles ^a   Panisko, Ellen A ^a   Smith, Richard D ^a   Wright, Aaron T ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY-BASED PROTEIN PROFILING; AEROBIC RESPIRATION; ASPERGILLUS FUMIGATUS; ENVIRONMENTAL ADAPTABILITY; ETHANOL FERMENTATION; EXTERNAL STIMULUS; FUNCTIONAL CHANGES; FUNGAL INFECTION; FUNGAL PATHOGEN; HUMAN PATHOGENS; HUMAN SERUM; METABOLIC ACTIVITY; PROGNOSTIC INDICATORS; PROTEOMICS; RAPID ASSESSMENT; STRESS RESPONSE;

ASPERGILLUS; ENZYMES; ETHANOL; MASS SPECTROMETRY; MOLECULAR BIOLOGY; MULTIPLEXING; PATHOGENS; PROTEINS;

BODY FLUIDS;

DIHYDROLIPOAMIDE DEHYDROGENASE; FUNGAL PROTEIN; PROTEOME; PYRUVIC ACID;

ANALYTIC METHOD; ARTICLE; ASPERGILLUS FUMIGATUS; BINDING SITE; BIOMASS; CELL CYCLE REGULATION; CONTROLLED STUDY; CULTURE TECHNIQUE; CYTOLYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FUNGAL METABOLISM; GLUCONEOGENESIS; GLYCOLYSIS; HOST PATHOGEN INTERACTION; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MULTIPLEXED ACTIVITY BASED PROTEIN PROFILING; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEOMICS; SERUM; STRESS;

ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; BIOCHEMISTRY; CULTURE MEDIA, SERUM-FREE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; LUNG; LUNG DISEASES; MASS SPECTROMETRY; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PROTEIN ARRAY ANALYSIS; PROTEOMICS; SERUM; TIME FACTORS;

ASPERGILLUS FUMIGATUS; FUNGI;

EID: 84866918143     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.394106     Document Type: Article

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