Serum stimulates growth of and proteinase secretion by Aspergillus fumigatus

Infection and Immunity

Volumn 70, Issue 1, 2002, Pages 19-26

  Gifford, A H T ^a   Klippenstein, J R ^a   Moore, M M ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN; FERRIC CHLORIDE; IRON BINDING PROTEIN; PROTEINASE; TRITIUM;

ARTICLE; ASPERGILLUS FUMIGATUS; BASEMENT MEMBRANE; CELL INVASION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME RELEASE; FUNGUS GROWTH; GROWTH INHIBITION; GROWTH STIMULATION; HEATING; HUMAN; HYDROLYSIS; ISOTOPE LABELING; MALE; NONHUMAN; NUTRIENT; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SERUM;

ANIMALS; ASPARTIC ENDOPEPTIDASES; ASPERGILLUS FUMIGATUS; BASEMENT MEMBRANE; CATTLE; CELL LINE; COLLAGENASES; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; ENZYME STABILITY; FERRIC COMPOUNDS; HEATING; HUMANS; HYDROLYSIS; IRON; METALLOENDOPEPTIDASES; SERINE ENDOPEPTIDASES; SERUM ALBUMIN, BOVINE;

EID: 0036138208     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.1.19-26.2002     Document Type: Article

References (50)

1. Effects of iron and desferrioxamine on Rhizopus infection
2. Lactoferrin is responsible for the fungistatic effect of human milk
3. A mechanism of susceptibility to mucormycosis in diabetic ketoacidosis: Transferrin and iron availability
4. Fungal infections in cancer patients: An international autopsy survey
5. Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies
6. Extracellular fibrinogenolytic enzyme of Aspergillus fumigatus: Substrate-dependent variations in the proteinase synthesis and characterization of the enzyme
7. The significance of iron in infection
8. Assaying proteinases with azocoll
9. Epidemiology of invasive fungal infections in bone marrow transplantation
10. Iron uptake from ferrioxamine and from ferrirhizoferrin by germinating spores of Rhizopus microsporus
11. Invasive aspergillosis
12. Amino acid metabolism in mammalian cell cultures
13. Susceptibility of Zygomycetes to human serum
14. Macrophage-mediated fungistasis: Requirement for a macromolecular component in serum
15. Isolation of the pericellular matrix of human fibroblast cultures
16. Acquisition, transport, and storage of iron by pathogenic fungi
17. Cloning and disruption of the gene encoding an extracellular metalloprotease of Aspergillus fumigatus
18. High levels of ferritin and its iron in fetal bovine serum
19. Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma
20. Evidence for possible involvement of an elastolytic serine protease in aspergillosis
21. Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice
22. Aspergillus fumigatus and aspergillosis
23. Molecular cloning of the cDNA and gene for an elastinolytic aspartic proteinase from Aspergillus fumigatus and evidence of its secretion by the fungus during invasion of the host lung
24. Purification and characterization of an elastinolytic metalloprotease from Aspergillus fumigatus and immunoelectron microscopic evidence of secretion of this enzyme by the fungus invading the murine lung
25. Invasive aspergillosis in patients with AIDS
26. Effect of iron on fluconazole activity against Candida albicans in presence of human serum or monocyte-derived macrophages
27. The secreted proteases of pathogenic species of Aspergillus and their possible role in virulence
28. Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus
29. Virulence of alkaline protease-deficient mutants of Aspergillus fumigatus
30. Isolation and characterisation of an extracellular alkaline protease of Aspergillus fumigatus
31. Degradation of human subendothelial extracellular matrix by proteinase-secreting Candida albicans
32. Different components in human serum inhibit multiplication of Cryptococcus neoformans and enhance fluconazole activity
33. Identification of extracellular siderophores of pathogenic strains of Aspergillus fumigatus
34. Comparison of the metal-binding anticandidal activities of serum and abscess fluid supernatants
35. Iron metabolism in pathogenic bacteria
36. Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue
37. Purification and characterization of an extracellular aspartic proteinase from Aspergillus fumigatus
38. Virulence of an aspergillopepsin-deficient mutant of Aspergillus fumigatus and evidence for another aspartic proteinase linked to the fungal cell wall
39. Aspergillus nidulans infection in chronic granulomatous disease
40. Characterization of an anticryptococcal protein isolated from human serum
41. Transferrin-dependent growth inhibition of yeast-phase Histoplasma capsulatum by human serum and lymph
42. The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis
43. Effects of iron on extracellular and intracellular growth of Penicillium marneffei
44. Interaction between Aspergillus fumigatus and basement membrane laminin: Binding and substrate degradation
45. Effect of ferrioxamine on the growth of Rhizopus
46. Epidemiology of Aspergillus infections in a large cohort of patients undergoing bone marrow transplantation
47. Infection and iron metabolism
48. The role of iron in protozoan and fungal infectious diseases
49. Biochemistry of iron uptake
50. Acquisition of iron from transferrin and lactoferrin by the protozoan Leishmania chagasi