In-cell selectivity profiling of serine protease inhibitors by activity-based proteomics

Molecular and Cellular Proteomics

Volumn 7, Issue 7, 2008, Pages 1241-1253

  Gillet, Ludovic C J ^a   Namoto, Kenji ^a   Ruchti, Alexandra ^a   Hoving, Sjouke ^a   Boesch, Danielle ^a   Inverardi, Bruno ^a   Mueller, Dieter ^a   Coulot, Michele ^a   Schindler, Patrick ^a   Schweigler, Patrick ^a   Bernardi, Anna ^a   Gil Parrado, Shirley ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PROLYL ENDOPEPTIDASE; SERINE DEHYDRATASE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; CELL LABELING; CELL LYSATE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CROSS COUPLING REACTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR PROBE; PRIMED IN SITU LABELING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FLUORESCENT DYES; HUMANS; MODELS, BIOLOGICAL; PHOSPHONIC ACIDS; PROTEOME; PROTEOMICS; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS; STAINING AND LABELING; SUBSTRATE SPECIFICITY;

EID: 47849084317     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.M700505-MCP200     Document Type: Article

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