Design, practical synthesis, and biological evaluation of novel 6-(Pyrazolylmethyl)-4-quinoline-3-carboxylic acid derivatives as HIV-1 integrase inhibitors

Molecules

Volumn 17, Issue 9, 2012, Pages 10652-10666

  Hu, Liming ^a   Yan, Song ^a   Luo, Zaigang ^a,b   Han, Xiao ^a   Wang, Yujie ^a   Wang, Zhanyang ^a   Zeng, Chengchu ^a  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^b ANHUI UNIVERSITY   (China)

Author keywords

HIV 1; Integrase inhibitors; Quinolone 3 carboxylic acid derivatives

Indexed keywords

CARBOXYLIC ACID; ELVITEGRAVIR; INTEGRASE; INTEGRASE INHIBITOR; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PYRAZOLE DERIVATIVE; QUINOLINE DERIVATIVE; QUINOLONE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; ENZYMOLOGY; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CARBOXYLIC ACIDS; DRUG DESIGN; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRAZOLES; QUINOLINES; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84866915203     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules170910652     Document Type: Article

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