Progress in the Development of Non-ATP-Competitive Protein Kinase Inhibitors for Oncology

Annual Reports in Medicinal Chemistry

Volumn 47, Issue , 2012, Pages 459-474

  McInnes, Campbell ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

CDK2; Cell cycle; Drug design; Inhibitor; Kinase; Oncology; PLK1; REPLACE

Indexed keywords

EID: 84866759429     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-396492-2.00029-1     Document Type: Chapter

References (49)

1. McInnes C., Fischer P.M. Curr. Pharm. Design 2005, 11:1845.
2. Kirkland L.O., McInnes C. Biochem. Pharmacol. 2009, 77:1561.
3. Garuti L., Roberti M., Bottegoni G. Curr. Med. Chem. 2010, 17:2804.
4. Andrews M.J., Kontopidis G., McInnes C., Plater A., Innes L., Cowan A., Fischer P.M. Chembiochem 1909, 2006:7.
5. Wang S., Griffiths G., Midgley C.A., Barnett A.L., Cooper M., Grabarek J., Fischer P.M. Chem. Biol. 2010, 17:1111.
6. McInnes C., Andrews M.J., Zheleva D.I., Lane D.P., Fischer P.M. Curr. Med. Chem. Anticancer Agents 2003, 3:57.
7. Zheleva D.I., McInnes C., Gavine A.L., Zhelev N.Z., Fischer P.M., Lane D.P. J. Pept. Res. 2002, 60:257.
8. Chen Y.N., Sharma S.K., Ramsey T.M., Jiang L., Martin M.S., Baker K., Adams P.D., Bair K.W., Kaelin W.G. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:4325.
9. Atkinson G.E., Cowan A., McInnes C., Zheleva D.I., Fischer P.M., Chan W.C. Bioorg. Med. Chem. Lett. 2002, 12:2501.
10. Mendoza N., Fong S., Marsters J., Koeppen H., Schwall R., Wickramasinghe D. Cancer Res. 2003, 63:1020.
11. Lowe E.D., Tews I., Cheng K.Y., Brown N.R., Gul S., Noble M.E., Gamblin S.J., Johnson L.N. Biochemistry 2002, 41:15625.
12. Kontopidis G., Andrews M.J., McInnes C., Cowan A., Powers H., Innes L., Fischer P.M. Structure 2003, 11:1537.
13. Castanedo G., Clark K., Wang S., Tsui V., Wong M., Nicholas J., Wickramasinghe D., Marsters J.C., Sutherlin D. Bioorg. Med. Chem. Lett. 2006, 16:1716.
14. Andrews M.J.I., McInnes C., Kontopidis G., Innes L., Cowan A., Plater A., Fischer P.M. Org. Biomol. Chem. 2004, 2:2735.
15. Carr R.A., Congreve M., Murray C.W., Rees D.C. Drug Discov. Today 2005, 10:987.
16. Nandha Premnath, P.; Bolger, J. K.; Liu, S.; McInnes, C. Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, 2011; Abstract nr 1351A.
17. Bolger, J. K.; Nandha Premnath, P.; Liu, S.; McInnes, C. Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, 2011, MEDI-67.
18. Liu S., Bolger J.K., Kirkland L.O., Premnath P.N., McInnes C. ACS Chem. Biol. 2010, 5:1169.
19. Larsen T.A., Olson A.J., Goodsell D.S. Structure 1998, 6:421.
20. Heitz F., Morris M.C., Fesquet D., Cavadore J.C., Dore M., Divita G. Biochemistry 1997, 36:4995.
21. Canela N., Orzáez M., Fucho R., Mateo F., Gutierrez R., Pineda-Lucena A., Bachs O., Pérez-Payá E. J. Biol. Chem. 2006, 281:35942.
22. Betzi S., Alam R., Martin M., Lubbers D.J., Han H., Jakkaraj S.R., Georg G.I., Schönbrunn E. ACS Chem. Biol. 2011, 6:492.
23. Lee K.S., Grenfell T.Z., Yarm F.R., Erikson R.L. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:9301.
24. Lee K.S., Song S., Erikson R.L. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:14360.
25. Yuan J., Kramer A., Eckerdt F., Kaufmann M., Strebhardt K. Cancer Res. 2002, 62:4186.
26. May K.M., Reynolds N., Cullen C.F., Yanagida M., Ohkura H. J. Cell. Biol. 2002, 156:23.
27. Nakajima H., Toyoshima-Morimoto F., Taniguchi E., Nishida E. J. Biol. Chem. 2003, 278:25277.
28. Neef R., Preisinger C., Sutcliffe J., Kopajtich R., Nigg E.A., Mayer T.U., Barr F.A. J. Cell. Biol. 2003, 162:863.
29. Cheng K.Y., Lowe E.D., Sinclair J., Nigg E.A., Johnson L.N. EMBO J. 2003, 22:5757.
30. Elia A.E.H., Rellos P., Haire L.F., Chao J.W., Ivins F.J., Hoepker K., Mohammad D., Cantley L.C., Smerdon S.J., Yaffe M.B. Cell 2003, 115:83.
31. Leung G.C., Hudson J.W., Kozarova A., Davidson A., Dennis J.W., Sicheri F. Nat. Struct. Biol. 2002, 9:719.
32. Garcia-Alvarez B., de Carcer G., Ibanez S., Bragado-Nilsson E., Montoya G. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:3107.
33. Pawson T., Scott J.D. Science 1997, 278:2075.
34. Sawyer T.K., Bohacek R.S., Dalgarno D.C., Eyermann C.J., Kawahata N., Metcalf C.A., Shakespeare W.C., Sundaramoorthi R., Wang Y., Yang M.G. Mini-Rev. Med. Chem. 2002, 2:475.
35. Fischer P.M. Curr. Med. Chem. 2004, 11:1563.
36. Bahassi E.M., Conn C.W., Myer D.L., Hennigan R.F., McGowan C.H., Sanchez Y., et al. Oncogene 2002, 21:6633.
37. Xie S., Wu H., Wang Q., Cogswell J.P., Husain I., Conn C., Stambrook P., Jhanwar-Uniyal M., Dai W. J. Biol. Chem. 2001, 276:43305.
38. Yun S.M., Moulaei T., Lim D., Bang J.K., Park J.E., Shenoy S.R., Liu F., Kang Y.H., Liao C., Soung N.K., Lee S., Yoon D.Y., Lim Y., Lee D.H., Otaka A., Appella E., McMahon J.B., Nicklaus M.C., Burke T.R., Yaffe M.B., Wlodawer A., Lee K.S. Nat. Struct. Mol. Biol. 2009, 16:876.
39. Lee H.J., Hwang H.I., Jang Y.J. Cell Cycle 2010, 9:2389-2398.
40. van Vugt V.A., Medema R.H. Cell Cycle 2004, 3:1383.
41. Smits V.A., Klompmaker R., Arnaud L., Rijksen G., Nigg E.A., Medema R.H. Nat. Cell. Biol. 2000, 2:672.
42. van Vugt M.A., Smits V.A., Klompmaker R., Medema R.H. J. Biol. Chem. 2001, 276:41656.
43. Reindl W., Yuan J., Kramer A., Strebhardt K., Berg T. Chem. Biol. 2008, 15:459.
44. Reindl W., Yuan J., Kramer A., Strebhardt K., Berg T. Chembiochem 2009, 10:1145.
45. Watanabe N., Sekine T., Takagi M., Iwasaki J., Imamoto N., Kawasaki H., Osada H. J. Biol. Chem. 2009, 284:2344.
46. Liu F., Park J.E., Qian W.J., Lim D., Graber M., Berg T., Yaffe M.B., Lee K.S., Burke T.R. Nat. Chem. Biol. 2011, 7:595.
47. Liu F., Park J.E., Qian W.J., Lim D., Scharow A., Berg T., Yaffe M.B., Lee K.S., Burke T.R. ACS Chem. Biol. 2012, 7:805-810.
48. Li Q., Huang Y., Xiao N., Murray V., Chen J., Wang J. Methods Cell. Biol. 2008, 90:287.
49. McInnes C., Estes K., Baxter M., Yang Z., Boshra Farag D., Johnson P., Lazo J., Wyatt M.D. Mol. Cancer Ther. 2012, 11:1683-1692.