Senescent remodeling of the immune system and its contribution to the predisposition of the elderly to infections

Chinese Medical Journal

Volumn 125, Issue 18, 2012, Pages 3325-3331

  Dewan, Sheilesh Kumar ^a   Zheng, Song bai ^a   Xia, Shi jin ^a   Bill, Kalionis ^b,c  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL WOMEN'S HOSPITAL   (Australia)

Author keywords

Adaptive immunity; Elderly; Immune risk profile; Immunological biomarker; Immunosenescence; Infections; Innate immunity; Senescent immune remodeling

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROSTAGLANDIN E2; RANTES; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADAPTIVE IMMUNITY; AGING; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHEMOTAXIS; DEFENSE MECHANISM; DENDRITIC CELL; DISEASE PREDISPOSITION; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNE SYSTEM; INFECTION; INNATE IMMUNITY; MACROPHAGE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; REGULATORY T LYMPHOCYTE;

ADAPTIVE IMMUNITY; AGING; ANIMALS; HUMANS; IMMUNE SYSTEM; IMMUNITY, INNATE; INFECTION;

EID: 84866707638     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.18.023     Document Type: Article

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