A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Hu, Pu ^a,b   Oomen, Charlotte ^a   van Dam, Anne Marie ^c   Wester, Jordi ^a   Zhou, Jiang Ning ^b   Joëls, Marian ^a,d   Lucassen, Paul J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b University of Science and Technology of China   (China)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CELL NUCLEUS ANTIGEN; DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC DRUG ADMINISTRATION; CHRONIC STRESS; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; HIPPOCAMPUS; HYPOPHYSIS ADRENAL SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL DIFFERENTIATION; NONHUMAN; RAT; SINGLE DRUG DOSE; TREATMENT DURATION; WEIGHT GAIN;

ANIMALS; BODY WEIGHT; CELL PROLIFERATION; CORTICOSTERONE; DENTATE GYRUS; GLUCOCORTICOIDS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MIFEPRISTONE; RATS; RATS, WISTAR;

RATTUS;

EID: 84866677982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046224     Document Type: Article

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