Glucocorticoid receptor and sequential P53 activation by Dexamethasone mediates apoptosis and cell cycle arrest of Osteoblastic MC3T3-E1 cells

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Li, Hui ^a   Qian, Wenwei ^a   Weng, Xisheng ^a   Wu, Zhihong ^a   Li, Huihua ^a   Zhuang, Qianyu ^a   Feng, Bin ^a   Bian, Yanyan ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID INDUCED LEUCINE ZIPPER PROTEIN; GLUCOCORTICOID RECEPTOR; GRANZYME A; LEUCINE ZIPPER PROTEIN; MIFEPRISTONE; PROTEIN NOXA; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; INHIBITION KINETICS; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NOXA GENE; OSTEOBLAST; PUMA GENE; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; RNA INTERFERENCE;

3T3 CELLS; ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE; DEXAMETHASONE; DNA PRIMERS; GENE SILENCING; MICE; MIFEPRISTONE; OSTEOBLASTS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GLUCOCORTICOID; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84862260783     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037030     Document Type: Article

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