Berberine, an isoquinoline alkaloid, inhibits the metastatic potential of breast cancer cells via Akt pathway modulation

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 38, 2012, Pages 9649-9658

  Kuo, Han Peng ^a   Chuang, Tzu Chao ^b   Tsai, Shih Chang ^a   Tseng, Hsiu Hsueh ^c   Hsu, Shih Chung ^d   Chen, Yu Chang ^a   Kuo, Chao Lin ^a   Kuo, Yueh Hsiung ^a   Liu, Jah Yao ^e   Kao, Ming Ching ^a,c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b TAMKANG UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d Kang Ning Junior College of Medical Care and Management   (Taiwan)

^e TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Akt PKB; berberine; breast cancer; matrix metalloproteinases; metastasis

Indexed keywords

AKT/PKB; BERBERINE; BREAST CANCER; MATRIX METALLOPROTEINASES; METASTASIS;

CELLS; DISEASES; METABOLITES; NITROGEN COMPOUNDS; PROTEINS;

ENZYME INHIBITION;

ANTINEOPLASTIC AGENT; BERBERINE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE INHIBITOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BREAST TUMOR; CELL ADHESION; CELL MOTION; CELL STRAIN MCF 7; CELL SURVIVAL; DRUG EFFECT; DRUG SCREENING; FEMALE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BERBERINE; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; MCF-7 CELLS; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84866666957     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf302832n     Document Type: Article

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