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Volumn 37, Issue 5, 2012, Pages 508-517

Molecular mechanisms of exercise-induced cardiovascular adaptations. Influence of epigenetics, mechanotransduction and free radicals;Molekulare mechanismen der herz- Und gefäßanpassung durch sport: Einfluss von epigenetik, mechanotrans-duktion und freien radikalen

Author keywords

Antioxidative capacity; Extracellular matrix; Functional genome; Nucleosomes; Oxidative stress; Signal transduction

Indexed keywords

FREE RADICAL;

EID: 84866550513     PISSN: 03409937     EISSN: 16156692     Source Type: Journal    
DOI: 10.1007/s00059-012-3637-6     Document Type: Article
Times cited : (11)

References (67)
  • 1
    • 0024438921 scopus 로고
    • Three models of free radical-induced cell injury
    • Comporti M (1989) Three models of free radical-induced cell injury. Chem Biol Interact 72:1-56.
    • (1989) Chem Biol Interact , vol.72 , pp. 1-56
    • Comporti, M.1
  • 2
    • 34147120588 scopus 로고    scopus 로고
    • Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction
    • Doerries C, Grote K, Hilfiker-Kleiner D et al (2007) Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction. Circ Res 100:894-903.
    • (2007) Circ Res , vol.100 , pp. 894-903
    • Doerries, C.1    Grote, K.2    Hilfiker-Kleiner, D.3
  • 3
    • 0032496159 scopus 로고    scopus 로고
    • Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes
    • Duranteau J, Chandel NS, Kulisz A et al (1998) Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem 273:11619-11624.
    • (1998) J Biol Chem , vol.273 , pp. 11619-11624
    • Duranteau, J.1    Chandel, N.S.2    Kulisz, A.3
  • 4
    • 21744447191 scopus 로고    scopus 로고
    • Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy?
    • Kojda G, Hambrecht R (2005) Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy? Cardiovasc Res 67:187-197.
    • (2005) Cardiovasc Res , vol.67 , pp. 187-197
    • Kojda, G.1    Hambrecht, R.2
  • 5
    • 27844607671 scopus 로고    scopus 로고
    • Reactive oxygen species production by mitochondria in endothelial cells exposed to reo-xygenation after hypoxia and glucose depletion is mediated by ceramide
    • Therade-Matharan S, Laemmel E, Carpentier S et al (2005) Reactive oxygen species production by mitochondria in endothelial cells exposed to reoxygenation after hypoxia and glucose depletion is mediated by ceramide. Am J Physiol Regul Integr Comp Physiol 289:R1756-R1762.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Therade-Matharan, S.1    Laemmel, E.2    Carpentier, S.3
  • 6
    • 3142718936 scopus 로고    scopus 로고
    • Changes in oxidative balance in rat pericytes exposed to diabetic conditions
    • Manea A, Constantinescu E, Popov D, Raicu M (2004) Changes in oxidative balance in rat pericy-tes exposed to diabetic conditions. J Cell Mol Med 8:117-126.
    • (2004) J Cell Mol Med , vol.8 , pp. 117-126
    • Manea, A.1    Constantinescu, E.2    Popov, D.3    Raicu, M.4
  • 7
    • 59849086158 scopus 로고    scopus 로고
    • Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: Toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2
    • Bae YS, Lee JH, Choi SH et al (2009) Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-de-pendent activation of NADPH oxidase 2. Circ Res 104:210-218.
    • (2009) Circ Res , vol.104 , pp. 210-218
    • Bae, Y.S.1    Lee, J.H.2    Choi, S.H.3
  • 8
    • 0024578749 scopus 로고
    • Higher antioxidative capacity during a chronic stable heart hypertrophy
    • Gupta M, Singal PK (1989) Higher antioxidative capacity during a chronic stable heart hypertrophy. Circ Res 64:398-406.
    • (1989) Circ Res , vol.64 , pp. 398-406
    • Gupta, M.1    Singal, P.K.2
  • 9
    • 34250772396 scopus 로고    scopus 로고
    • Exercise training normalizes sympathetic outflow by central antioxidant mechanisms in rabbits with pacing-induced chronic heart failure
    • Gao L, Wang W, Liu D, Zucker IH (2007) Exercise training normalizes sympathetic outflow by cen-tral antioxidant mechanisms in rabbits with pacing-induced chronic heart failure. Circulation 115:3095-3102.
    • (2007) Circulation , vol.115 , pp. 3095-3102
    • Gao, L.1    Wang, W.2    Liu, D.3    Zucker, I.H.4
  • 10
    • 81355163633 scopus 로고    scopus 로고
    • Exercise-induced adaptations of cardiac redox homeostasis and remodeling in heterozygous SOD2-knockout mice
    • Richters L, Lange N, Renner R et al (2011) Exercise-induced adaptations of cardiac redox homeostasis and remodeling in heterozygous SOD2-knockout mice. J Appl Physiol 111:1431-1440.
    • (2011) J Appl Physiol , vol.111 , pp. 1431-1440
    • Richters, L.1    Lange, N.2    Renner, R.3
  • 11
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge heart anti-oxidant study, CHAOS
    • Stephens NG, Parsons A, Schofield PM et al (1996) Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347:781-786.
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3
  • 12
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG (1993) Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 91:2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 13
    • 53249096016 scopus 로고    scopus 로고
    • Reactive oxygen species: Finding the right balance
    • Morrell CN (2008) Reactive oxygen species: finding the right balance. Circ Res 103:571-572.
    • (2008) Circ Res , vol.103 , pp. 571-572
    • Morrell, C.N.1
  • 14
    • 0032403050 scopus 로고    scopus 로고
    • Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells
    • Gozin A, Franzini E, Andrieu V et al (1998) Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells. Free Radic Biol Med 25:1021-1032.
    • (1998) Free Radic Biol Med , vol.25 , pp. 1021-1032
    • Gozin, A.1    Franzini, E.2    Andrieu, V.3
  • 15
    • 79955633419 scopus 로고    scopus 로고
    • The forgotten face of regular physical exercise: A 'natural' anti-atherogenic activity
    • Szostak J, Laurant P (2011) The forgotten face of regular physical exercise: a 'natural' anti-atherogenic activity. Clin Sci (Lond) 121:91-106.
    • (2011) Clin Sci, Lond , vol.121 , pp. 91-106
    • Szostak, J.1    Laurant, P.2
  • 16
    • 33748476312 scopus 로고    scopus 로고
    • Role of exercise intensities in oxidized low-density lipoprotein-mediated redox status of monocyte in men
    • Wang JS, Lee T, Chow SE (2006) Role of exercise intensities in oxidized low-density lipoprotein-mediated redox status of monocyte in men. J Appl Physiol 101:740-744.
    • (2006) J Appl Physiol , vol.101 , pp. 740-744
    • Wang, J.S.1    Lee, T.2    Chow, S.E.3
  • 17
    • 0142245805 scopus 로고    scopus 로고
    • Modulation of physiological angiogenesis in skeletal muscle by mechanical forces: Involvement of VEGF and metalloproteinases
    • Brown MD, Hudlicka O (2003) Modulation of physiological angiogenesis in skeletal muscle by me-chanical forces: involvement of VEGF and metalloproteinases. Angiogenesis 6:1-14.
    • (2003) Angiogenesis , vol.6 , pp. 1-14
    • Brown, M.D.1    Hudlicka, O.2
  • 18
    • 6044260112 scopus 로고    scopus 로고
    • Voluntary running induces fiber type-specific angiogenesis in mouse skeletal muscle
    • Waters RE, Rotevatn S, Li P et al (2004) Voluntary running induces fiber type-specific angiogenesis in mouse skeletal muscle. Am J Physiol Cell Physiol 287:C1342-C1348.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Waters, R.E.1    Rotevatn, S.2    Li, P.3
  • 19
    • 34547685847 scopus 로고    scopus 로고
    • Effects of short-term vibration and hypoxia during high-intensity cycling exercise on circulating levels of angiogenic regulators in humans
    • Suhr F, Brixius K de MM, Bolck B et al (2007) Effects of short-term vibration and hypoxia during high-intensity cycling exercise on circulating levels of angiogenic regulators in humans. J Appl Physiol 103:474-483.
    • (2007) J Appl Physiol , vol.103 , pp. 474-483
    • Suhr, F.1    De Brixius, K.M.M.2    Bolck, B.3
  • 20
    • 84860759450 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species and JNK in increased expression of MCP-1 and infiltration of inflammatory cells in pressure-overloaded rat hearts
    • Shang F, Wang J, Liu X et al (2012) Involvement of reactive oxygen species and JNK in increased expression of MCP-1 and infiltration of inflammatory cells in pressure-overloaded rat hearts. Mol Med Report 5(6):1491-1496.
    • (2012) Mol Med Report , vol.5 , Issue.6 , pp. 1491-1496
    • Shang, F.1    Wang, J.2    Liu, X.3
  • 21
    • 79958050648 scopus 로고    scopus 로고
    • Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases
    • Martinez-Lemus LA, Zhao G, Galinanes EL, Boone M (2011) Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases. Am J Physiol Heart Circ Physiol 300:H2005-H2015.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300
    • Martinez-Lemus, L.A.1    Zhao, G.2    Galinanes, E.L.3    Boone, M.4
  • 22
    • 33846991976 scopus 로고    scopus 로고
    • Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase
    • Biswas S, Gupta MK, Chattopadhyay D, Mukhopadhyay CK (2007) Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. Am J Physiol Heart Circ Physiol 292:H758-H766.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Biswas, S.1    Gupta, M.K.2    Chattopadhyay, D.3    Mukhopadhyay, C.K.4
  • 23
    • 80052197530 scopus 로고    scopus 로고
    • Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species
    • Wang Y, Zang QS, Liu Z et al (2011) Regulation of VEGF-induced endothelial cell migration by mi-tochondrial reactive oxygen species. Am J Physiol Cell Physiol 301:C695-C704.
    • (2011) Am J Physiol Cell Physiol , vol.301
    • Wang, Y.1    Zang, Q.S.2    Liu, Z.3
  • 24
    • 77955092333 scopus 로고    scopus 로고
    • Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis
    • Kliment CR, Oury TD (2010) Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis. Free Radic Biol Med 49:707-717.
    • (2010) Free Radic Biol Med , vol.49 , pp. 707-717
    • Kliment, C.R.1    Oury, T.D.2
  • 25
    • 84855462583 scopus 로고    scopus 로고
    • Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species
    • Giedt RJ, Yang C, Zweier JL et al (2012) Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radic Biol Med 52:348-356.
    • (2012) Free Radic Biol Med , vol.52 , pp. 348-356
    • Giedt, R.J.1    Yang, C.2    Zweier, J.L.3
  • 26
    • 4344583344 scopus 로고    scopus 로고
    • What makes vessels grow with exercise training?
    • Prior BM, Yang HT, Terjung RL (2004) What makes vessels grow with exercise training? J Appl Physiol 97:1119-1128.
    • (2004) J Appl Physiol , vol.97 , pp. 1119-1128
    • Prior, B.M.1    Yang, H.T.2    Terjung, R.L.3
  • 27
    • 9244228465 scopus 로고    scopus 로고
    • Effect of exercise training on endothelium-derived nitric oxide function in humans
    • Green DJ, Maiorana A, O'Driscoll G, Taylor R (2004) Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561:1-25.
    • (2004) J Physiol , vol.561 , pp. 1-25
    • Green, D.J.1    Maiorana, A.2    O'Driscoll, G.3    Taylor, R.4
  • 28
    • 33646449520 scopus 로고    scopus 로고
    • Akt1 is required for physiological cardiac growth
    • DeBosch B, Treskov I, Lupu TS et al (2006) Akt1 is required for physiological cardiac growth. Circulation 113:2097-2104.
    • (2006) Circulation , vol.113 , pp. 2097-2104
    • Debosch, B.1    Treskov, I.2    Lupu, T.S.3
  • 29
    • 0142027759 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
    • McMullen JR, Shioi T, Zhang L et al (2003) Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci U S A 100:12355-12360.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12355-12360
    • McMullen, J.R.1    Shioi, T.2    Zhang, L.3
  • 30
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110:673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 31
    • 72449170101 scopus 로고    scopus 로고
    • TRPC1 channels are critical for hypertrophic signaling in the heart
    • Seth M, Zhang ZS, Mao L et al (2009) TRPC1 channels are critical for hypertrophic signaling in the heart. Circ Res 105:1023-1030.
    • (2009) Circ Res , vol.105 , pp. 1023-1030
    • Seth, M.1    Zhang, Z.S.2    Mao, L.3
  • 32
    • 79960237085 scopus 로고    scopus 로고
    • Ca2+ regulatory mechanisms of exercise protection against coronary artery disease in metabolic syndrome and diabetes
    • Sturek M (2011) Ca2+ regulatory mechanisms of exercise protection against coronary artery disease in metabolic syndrome and diabetes. J Appl Physiol 111:573-586.
    • (2011) J Appl Physiol , vol.111 , pp. 573-586
    • Sturek, M.1
  • 33
    • 84858709388 scopus 로고    scopus 로고
    • Overexpression of coupling factor 6 attenuates exercise-induced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice
    • Sagara S, Osanai T, Itoh T et al (2012) Overexpression of coupling factor 6 attenuates exercise-in-duced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice. J Hypertens 30:778-786.
    • (2012) J Hypertens , vol.30 , pp. 778-786
    • Sagara, S.1    Osanai, T.2    Itoh, T.3
  • 34
    • 80053046816 scopus 로고    scopus 로고
    • Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart
    • Knoll R, Linke WA, Zou P et al (2011) Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart. Circ Res 109:758-769.
    • (2011) Circ Res , vol.109 , pp. 758-769
    • Knoll, R.1    Linke, W.A.2    Zou, P.3
  • 35
    • 64249157458 scopus 로고    scopus 로고
    • Angiogenic and vascular modulation by extracellular matrix cleavage products
    • Suhr F, Brixius K, Bloch W (2009) Angiogenic and vascular modulation by extracellular matrix clea-vage products. Curr Pharm Des 15:389-410.
    • (2009) Curr Pharm des , vol.15 , pp. 389-410
    • Suhr, F.1    Brixius, K.2    Bloch, W.3
  • 36
    • 3042521356 scopus 로고    scopus 로고
    • Influence of endostatin on embryonic vasculo- and angiogenesis
    • Schmidt A, Wenzel D, Ferring I et al (2004) Influence of endostatin on embryonic vasculo- and an-giogenesis. Dev Dyn 230:468-480.
    • (2004) Dev Dyn , vol.230 , pp. 468-480
    • Schmidt, A.1    Wenzel, D.2    Ferring, I.3
  • 37
    • 0034575632 scopus 로고    scopus 로고
    • The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing
    • Bloch W, Huggel K, Sasaki T et al (2000) The angiogenesis inhibitor endostatin impairs blood ves-sel maturation during wound healing. FASEB J 14:2373-2376.
    • (2000) FASEB J , vol.14 , pp. 2373-2376
    • Bloch, W.1    Huggel, K.2    Sasaki, T.3
  • 38
    • 33745049511 scopus 로고    scopus 로고
    • Endostatin, the proteolytic fragment of collagen XVIII, induces vasorelaxation
    • Wenzel D, Schmidt A, Reimann K et al (2006) Endostatin, the proteolytic fragment of collagen XVIII, induces vasorelaxation. Circ Res 98:1203-1211.
    • (2006) Circ Res , vol.98 , pp. 1203-1211
    • Wenzel, D.1    Schmidt, A.2    Reimann, K.3
  • 39
    • 70349667325 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury activates early extracellular matrix processing and expression of endostatin in the heart with differential effects of temperature
    • Lauten A, Majos E, Muhlich A et al (2009) Ischemia-reperfusion injury activates early extracellular matrix processing and expression of endostatin in the heart with differential effects of temperature. Basic Res Cardiol 104:559-569.
    • (2009) Basic Res Cardiol , vol.104 , pp. 559-569
    • Lauten, A.1    Majos, E.2    Muhlich, A.3
  • 40
    • 77952517509 scopus 로고    scopus 로고
    • Regulation of extracellular matrix compounds involved in angiogenic processes in short- and long-track elite runners
    • Suhr F, Rosenwick C, Vassiliadis A et al (2010) Regulation of extracellular matrix compounds involved in angiogenic processes in short- and long-track elite runners. Scand J Med Sci Sports 20:441-448.
    • (2010) Scand J Med Sci Sports , vol.20 , pp. 441-448
    • Suhr, F.1    Rosenwick, C.2    Vassiliadis, A.3
  • 41
    • 39449093705 scopus 로고    scopus 로고
    • Long-term endurance exercise decreases antiangiogenic endostatin signalling in overweight men aged 50-60 years
    • Brixius K, Schoenberger S, Ladage D et al (2008) Long-term endurance exercise decreases antian-giogenic endostatin signalling in overweight men aged 50-60 years. Br J Sports Med 42:126-129.
    • (2008) Br J Sports Med , vol.42 , pp. 126-129
    • Brixius, K.1    Schoenberger, S.2    Ladage, D.3
  • 42
    • 0030695332 scopus 로고    scopus 로고
    • Chromatin remodeling and the control of gene expression
    • Wu C (1997) Chromatin remodeling and the control of gene expression. J Biol Chem 272:28171-28174.
    • (1997) J Biol Chem , vol.272 , pp. 28171-28174
    • Wu, C.1
  • 43
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD (2001) Translating the histone code. Science 293:1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 44
    • 59749094084 scopus 로고    scopus 로고
    • Epigenetic histone acetylation modifiers in vascular remodelling: New targets for therapy in cardiovascular disease
    • Pons D, Vries FR de, Elsen PJ van den et al (2009) Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease. Eur Heart J 30:266-277.
    • (2009) Eur Heart J , vol.30 , pp. 266-277
    • Pons, D.1    Vries, F.R.D.2    Van Den Elsen, P.J.3
  • 45
    • 0028330005 scopus 로고
    • Genetic susceptibility to death from coronary heart disease in a study of twins
    • Marenberg ME, Risch N, Berkman LF et al (1994) Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med 330:1041-1046.
    • (1994) N Engl J Med , vol.330 , pp. 1041-1046
    • Marenberg, M.E.1    Risch, N.2    Berkman, L.F.3
  • 46
    • 77956335920 scopus 로고    scopus 로고
    • Exercise effects on methylation of ASC gene
    • Nakajima K, Takeoka M, Mori M et al (2010) Exercise effects on methylation of ASC gene. Int J Sports Med 31:671-675.
    • (2010) Int J Sports Med , vol.31 , pp. 671-675
    • Nakajima, K.1    Takeoka, M.2    Mori, M.3
  • 47
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M (1997) Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 48
    • 0842308109 scopus 로고    scopus 로고
    • Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: Role of tyrosine nitration
    • Ito K, Hanazawa T, Tomita K et al (2004) Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun 315:240-245.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 240-245
    • Ito, K.1    Hanazawa, T.2    Tomita, K.3
  • 49
    • 0033821409 scopus 로고    scopus 로고
    • Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
    • Ito K, Barnes PJ, Adcock IM (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20:6891-6903.
    • (2000) Mol Cell Biol , vol.20 , pp. 6891-6903
    • Ito, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 50
    • 0035839497 scopus 로고    scopus 로고
    • P65-activated histone acetyltransferase activity is repressed by glucocorticoids: Mifepristone fails to recruit HDAC2 to the p65-HAT complex
    • Ito K, Jazrawi E, Cosio B et al (2001) p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex. J Biol Chem 276:30208-30215.
    • (2001) J Biol Chem , vol.276 , pp. 30208-30215
    • Ito, K.1    Jazrawi, E.2    Cosio, B.3
  • 51
    • 2342423022 scopus 로고    scopus 로고
    • In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
    • Miao F, Gonzalo IG, Lanting L, Natarajan R (2004) In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J Biol Chem 279:18091-18097.
    • (2004) J Biol Chem , vol.279 , pp. 18091-18097
    • Miao, F.1    Gonzalo, I.G.2    Lanting, L.3    Natarajan, R.4
  • 52
    • 33645867979 scopus 로고    scopus 로고
    • Association of plasma eotaxin levels with the presence and extent of angiographic coronary artery disease
    • Emanuele E, Falcone C, D'Angelo A et al (2006) Association of plasma eotaxin levels with the presence and extent of angiographic coronary artery disease. Atherosclerosis 186:140-145.
    • (2006) Atherosclerosis , vol.186 , pp. 140-145
    • Emanuele, E.1    Falcone, C.2    D'Angelo, A.3
  • 53
    • 21244495174 scopus 로고    scopus 로고
    • Beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation
    • Nie M, Knox AJ, Pang L (2005) beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation. J Immunol 175:478-486.
    • (2005) J Immunol , vol.175 , pp. 478-486
    • Nie, M.1    Knox, A.J.2    Pang, L.3
  • 54
    • 0033609093 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor prevents the progression of atherosclerosis via changes in the cellular and extracellular composition of atherosclerotic lesions in watanabe herita-ble hyperlipidemic rabbits
    • Shindo J, Ishibashi T, Yokoyama K et al (1999) Granulocyte-macrophage colony-stimulating factor prevents the progression of atherosclerosis via changes in the cellular and extracellular composition of atherosclerotic lesions in watanabe heritable hyperlipidemic rabbits. Circulation 99:2150-2156.
    • (1999) Circulation , vol.99 , pp. 2150-2156
    • Shindo, J.1    Ishibashi, T.2    Yokoyama, K.3
  • 55
    • 34249736457 scopus 로고    scopus 로고
    • Programming smooth muscle plasticity with chromatin dynamics
    • McDonald OG, Owens GK (2007) Programming smooth muscle plasticity with chromatin dyna-mics. Circ Res 100:1428-1441.
    • (2007) Circ Res , vol.100 , pp. 1428-1441
    • McDonald, O.G.1    Owens, G.K.2
  • 56
    • 31044442783 scopus 로고    scopus 로고
    • Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo
    • McDonald OG, Wamhoff BR, Hoofnagle MH, Owens GK (2006) Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. J Clin Invest 116:36-48.
    • (2006) J Clin Invest , vol.116 , pp. 36-48
    • McDonald, O.G.1    Wamhoff, B.R.2    Hoofnagle, M.H.3    Owens, G.K.4
  • 57
    • 0642309886 scopus 로고    scopus 로고
    • Hyper nuclear acetylation (HNA) in proliferation, differentiation and apoptosis
    • Kawahara K, Kawabata H, Aratani S, Nakajima T (2003) Hyper nuclear acetylation (HNA) in prolife-ration, differentiation and apoptosis. Ageing Res Rev 2:287-297.
    • (2003) Ageing Res Rev , vol.2 , pp. 287-297
    • Kawahara, K.1    Kawabata, H.2    Aratani, S.3    Nakajima, T.4
  • 58
    • 33847227712 scopus 로고    scopus 로고
    • Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21, WAF1
    • Okamoto H, Fujioka Y, Takahashi A et al (2006) Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). J Atheroscler Thromb 13:183-191.
    • (2006) J Atheroscler Thromb , vol.13 , pp. 183-191
    • Okamoto, H.1    Fujioka, Y.2    Takahashi, A.3
  • 59
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P (1994) Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 94:2493-2503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 60
    • 26244457666 scopus 로고    scopus 로고
    • Effect of sodium butyrate on pro-matrix metalloproteinase-9 and -2 differential secretion in pediatric tumors and cell lines
    • Rodriguez-Salvador J, Armas-Pineda C, Perezpena-Diazconti M et al (2005) Effect of sodium butyrate on pro-matrix metalloproteinase-9 and -2 differential secretion in pediatric tumors and cell lines. J Exp Clin Cancer Res 24:463-473.
    • (2005) J Exp Clin Cancer Res , vol.24 , pp. 463-473
    • Rodriguez-Salvador, J.1    Armas-Pineda, C.2    Perezpena-Diazconti, M.3
  • 61
    • 0036401604 scopus 로고    scopus 로고
    • Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression
    • Ailenberg M, Silverman M (2002) Trichostatin A-histone deacetylase inhibitor with clinical thera-peutic potential-is also a selective and potent inhibitor of gelatinase A expression. Biochem Biophys Res Commun 298:110-115.
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 110-115
    • Ailenberg, M.1    Silverman, M.2
  • 62
    • 0038408486 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion
    • Liu LT, Chang HC, Chiang LC, Hung WC (2003) Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Cancer Res 63:3069-3072.
    • (2003) Cancer Res , vol.63 , pp. 3069-3072
    • Liu, L.T.1    Chang, H.C.2    Chiang, L.C.3    Hung, W.C.4
  • 63
    • 21644471962 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption
    • Young DA, Lakey RL, Pennington CJ et al (2005) Histone deacetylase inhibitors modulate metall-oproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Res Ther 7:R503-R512.
    • (2005) Arthritis Res Ther , vol.7
    • Young, D.A.1    Lakey, R.L.2    Pennington, C.J.3
  • 64
    • 30544453439 scopus 로고    scopus 로고
    • Molecular aspects of atherogenesis: New insights and unsolved questions
    • Puddu GM, Cravero E, Arnone G et al (2005) Molecular aspects of atherogenesis: new insights and unsolved questions. J Biomed Sci 12:839-853.
    • (2005) J Biomed Sci , vol.12 , pp. 839-853
    • Puddu, G.M.1    Cravero, E.2    Arnone, G.3
  • 65
    • 11144250262 scopus 로고    scopus 로고
    • Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin
    • Cao D, Wang Z, Zhang CL et al (2005) Modulation of smooth muscle gene expression by associati-on of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol 25:364-376.
    • (2005) Mol Cell Biol , vol.25 , pp. 364-376
    • Cao, D.1    Wang, Z.2    Zhang, C.L.3
  • 66
    • 80052992257 scopus 로고    scopus 로고
    • Diet-induced lethality due to deletion of the Hdac3 gene in heart and skeletal muscle
    • Sun Z, Singh N, Mullican SE et al (2011) Diet-induced lethality due to deletion of the Hdac3 gene in heart and skeletal muscle. J Biol Chem 286:33301-33309.
    • (2011) J Biol Chem , vol.286 , pp. 33301-33309
    • Sun, Z.1    Singh, N.2    Mullican, S.E.3
  • 67
    • 55849084700 scopus 로고    scopus 로고
    • Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice
    • Montgomery RL, Potthoff MJ, Haberland M et al (2008) Maintenance of cardiac energy metabo-lism by histone deacetylase 3 in mice. J Clin Invest 118:3588-3597.
    • (2008) J Clin Invest , vol.118 , pp. 3588-3597
    • Montgomery, R.L.1    Potthoff, M.J.2    Haberland, M.3


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