-
1
-
-
79953137657
-
Copper promotes the trafficking of the amyloid precursor protein
-
K.M. Acevedo, Y.H. Hung, A.H. Dalziel, Q.X. Li, K. Laughton, K. Wikhe, A. Rembach, B. Roberts, C.L. Masters, A.I. Bush, and J. Camakaris Copper promotes the trafficking of the amyloid precursor protein J. Biol. Chem. 286 2011 8252 8262
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 8252-8262
-
-
Acevedo, K.M.1
Hung, Y.H.2
Dalziel, A.H.3
Li, Q.X.4
Laughton, K.5
Wikhe, K.6
Rembach, A.7
Roberts, B.8
Masters, C.L.9
Bush, A.I.10
Camakaris, J.11
-
2
-
-
24044479679
-
BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper
-
B. Angeletti, K.J. Waldron, K.B. Freeman, H. Bawagan, I. Hussain, C.C. Miller, K.F. Lau, M.E. Tennant, C. Dennison, N.J. Robinson, and C. Dingwall BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper J. Biol. Chem. 280 2005 17930 17937
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17930-17937
-
-
Angeletti, B.1
Waldron, K.J.2
Freeman, K.B.3
Bawagan, H.4
Hussain, I.5
Miller, C.C.6
Lau, K.F.7
Tennant, M.E.8
Dennison, C.9
Robinson, N.J.10
Dingwall, C.11
-
3
-
-
76649093635
-
Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein
-
C. Balducci, M. Beeg, M. Stravalaci, A. Bastone, A. Sclip, E. Biasini, L. Tapella, L. Colombo, C. Manzoni, T. Borsello, R. Chiesa, M. Gobbi, M. Salmona, and G. Forloni Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein Proc. Natl. Acad. Sci. USA 107 2010 2295 2300
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2295-2300
-
-
Balducci, C.1
Beeg, M.2
Stravalaci, M.3
Bastone, A.4
Sclip, A.5
Biasini, E.6
Tapella, L.7
Colombo, L.8
Manzoni, C.9
Borsello, T.10
Chiesa, R.11
Gobbi, M.12
Salmona, M.13
Forloni, G.14
-
4
-
-
0035254585
-
Prion and prejudice: Normal protein and the synapse
-
D.R. Brown Prion and prejudice: normal protein and the synapse Trends Neurosci. 24 2001 85 90
-
(2001)
Trends Neurosci.
, vol.24
, pp. 85-90
-
-
Brown, D.R.1
-
5
-
-
30944453898
-
Neurodegeneration and oxidative stress: Prion disease results from loss of antioxidant defence
-
D.R. Brown Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence Folia Neuropathol. 43 2005 229 243
-
(2005)
Folia Neuropathol.
, vol.43
, pp. 229-243
-
-
Brown, D.R.1
-
6
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
D.R. Brown, K. Qin, J.W. Herms, A. Madlung, J. Manson, R. Strome, P.E. Fraser, T. Kruck, A. von Bohlen, W. Schulz-Schaeffer, A. Giese, D. Westaway, and H. Kretzschmar The cellular prion protein binds copper in vivo Nature 390 1997 684 687
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.8
Von Bohlen, A.9
Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.13
-
7
-
-
0033571055
-
Normal prion protein has an activity like that of superoxide dismutase
-
D.R. Brown, B.S. Wong, F. Hafiz, C. Clive, S.J. Haswell, and I.M. Jones Normal prion protein has an activity like that of superoxide dismutase Biochem. J. 344 Pt 1 1999 1 5
-
(1999)
Biochem. J.
, vol.344
, Issue.PART 1
, pp. 1-5
-
-
Brown, D.R.1
Wong, B.S.2
Hafiz, F.3
Clive, C.4
Haswell, S.J.5
Jones, I.M.6
-
8
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
H. Bueler, M. Fischer, Y. Lang, H. Bluethmann, H.P. Lipp, S.J. DeArmond, S.B. Prusiner, M. Aguet, and C. Weissmann Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein Nature 356 1992 577 582
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Bueler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.P.5
Dearmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
9
-
-
0037646939
-
Copper coordination in the full-length, recombinant prion protein
-
C.S. Burns, E. Aronoff-Spencer, G. Legname, S.B. Prusiner, W.E. Antholine, G.J. Gerfen, J. Peisach, and G.L. Millhauser Copper coordination in the full-length, recombinant prion protein Biochemistry 42 2003 6794 6803
-
(2003)
Biochemistry
, vol.42
, pp. 6794-6803
-
-
Burns, C.S.1
Aronoff-Spencer, E.2
Legname, G.3
Prusiner, S.B.4
Antholine, W.E.5
Gerfen, G.J.6
Peisach, J.7
Millhauser, G.L.8
-
10
-
-
77956165325
-
Prion protein and Abeta-related synaptic toxicity impairment
-
A.M. Calella, M. Farinelli, M. Nuvolone, O. Mirante, R. Moos, J. Falsig, I.M. Mansuy, and A. Aguzzi Prion protein and Abeta-related synaptic toxicity impairment EMBO Mol. Med. 2 2010 306 314
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 306-314
-
-
Calella, A.M.1
Farinelli, M.2
Nuvolone, M.3
Mirante, O.4
Moos, R.5
Falsig, J.6
Mansuy, I.M.7
Aguzzi, A.8
-
11
-
-
79960629063
-
Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases
-
O. Calero, M.J. Bullido, J. Clarimon, A. Frank-Garcia, P. Martinez-Martin, A. Lleo, M.J. Rey, A. Rabano, R. Blesa, T. Gomez-Isla, F. Valdivieso, J. de Pedro-Cuesta, I. Ferrer, and M. Calero Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases PLoS One 6 2011 e22090
-
(2011)
PLoS One
, vol.6
, pp. 22090
-
-
Calero, O.1
Bullido, M.J.2
Clarimon, J.3
Frank-Garcia, A.4
Martinez-Martin, P.5
Lleo, A.6
Rey, M.J.7
Rabano, A.8
Blesa, R.9
Gomez-Isla, T.10
Valdivieso, F.11
De Pedro-Cuesta, J.12
Ferrer, I.13
Calero, M.14
-
12
-
-
0034613345
-
Maturation and pro-peptide cleavage of beta-secretase
-
A. Capell, H. Steiner, M. Willem, H. Kaiser, C. Meyer, J. Walter, S. Lammich, G. Multhaup, and C. Haass Maturation and pro-peptide cleavage of beta-secretase J. Biol. Chem. 275 2000 30849 30854
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30849-30854
-
-
Capell, A.1
Steiner, H.2
Willem, M.3
Kaiser, H.4
Meyer, C.5
Walter, J.6
Lammich, S.7
Multhaup, G.8
Haass, C.9
-
13
-
-
77956197815
-
Interaction between human prion protein and amyloid-beta (Abeta) oligomers: Role of N-terminal residues
-
S. Chen, S.P. Yadav, and W.K. Surewicz Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues J. Biol. Chem. 285 2010 26377 26383
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26377-26383
-
-
Chen, S.1
Yadav, S.P.2
Surewicz, W.K.3
-
14
-
-
0842309491
-
Beta-secretase inhibition for the treatment of Alzheimer's disease-promise and challenge
-
M. Citron Beta-secretase inhibition for the treatment of Alzheimer's disease-promise and challenge Trends Pharmacol. Sci. 25 2004 92 97
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 92-97
-
-
Citron, M.1
-
15
-
-
57649217285
-
The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology
-
S.L. Cole, and R. Vassar The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology J. Biol. Chem. 283 2008 29621 29625
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29621-29625
-
-
Cole, S.L.1
Vassar, R.2
-
16
-
-
65249118776
-
Thermodynamic and voltammetric characterization of the metal binding to the prion protein: Insights into pH dependence and redox chemistry
-
P. Davies, F. Marken, S. Salter, and D.R. Brown Thermodynamic and voltammetric characterization of the metal binding to the prion protein: insights into pH dependence and redox chemistry Biochemistry 48 2009 2610 2619
-
(2009)
Biochemistry
, vol.48
, pp. 2610-2619
-
-
Davies, P.1
Marken, F.2
Salter, S.3
Brown, D.R.4
-
17
-
-
79251572323
-
Alpha-synuclein is a cellular ferrireductase
-
P. Davies, D. Moualla, and D.R. Brown Alpha-synuclein is a cellular ferrireductase PLoS One 6 2011 e15814
-
(2011)
PLoS One
, vol.6
, pp. 15814
-
-
Davies, P.1
Moualla, D.2
Brown, D.R.3
-
18
-
-
79953297068
-
BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin
-
G.M. Finan, H. Okada, and T.W. Kim BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin J. Biol. Chem. 286 2011 12602 12616
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12602-12616
-
-
Finan, G.M.1
Okada, H.2
Kim, T.W.3
-
19
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
M. Fischer, T. Rulicke, A. Raeber, A. Sailer, M. Moser, B. Oesch, S. Brandner, A. Aguzzi, and C. Weissmann Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie EMBO J. 15 1996 1255 1264
-
(1996)
EMBO J.
, vol.15
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
Sailer, A.4
Moser, M.5
Oesch, B.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
20
-
-
78651410464
-
Beta-amyloid oligomers and prion protein: Fatal attraction?
-
G. Forloni, and C. Balducci Beta-amyloid oligomers and prion protein: Fatal attraction? Prion 5 2011 10 15
-
(2011)
Prion
, vol.5
, pp. 10-15
-
-
Forloni, G.1
Balducci, C.2
-
21
-
-
77951876319
-
Memory impairment in transgenic Alzheimer mice requires cellular prion protein
-
D.A. Gimbel, H.B. Nygaard, E.E. Coffey, E.C. Gunther, J. Lauren, Z.A. Gimbel, and S.M. Strittmatter Memory impairment in transgenic Alzheimer mice requires cellular prion protein J. Neurosci. 30 2010 6367 6374
-
(2010)
J. Neurosci.
, vol.30
, pp. 6367-6374
-
-
Gimbel, D.A.1
Nygaard, H.B.2
Coffey, E.E.3
Gunther, E.C.4
Lauren, J.5
Gimbel, Z.A.6
Strittmatter, S.M.7
-
22
-
-
78650426197
-
Deficiency of the copper chaperone for superoxide dismutase increases amyloid-beta production
-
E.H. Gray, K.J. De Vos, C. Dingwall, M.S. Perkinton, and C.C. Miller Deficiency of the copper chaperone for superoxide dismutase increases amyloid-beta production J. Alzheimers Dis. 21 2010 1101 1105
-
(2010)
J. Alzheimers Dis.
, vol.21
, pp. 1101-1105
-
-
Gray, E.H.1
De Vos, K.J.2
Dingwall, C.3
Perkinton, M.S.4
Miller, C.C.5
-
23
-
-
80052979854
-
Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and swedish mutant amyloid precursor protein
-
H.H. Griffiths, I.J. Whitehouse, H. Baybutt, D. Brown, K.A. Kellett, C.D. Jackson, A.J. Turner, P. Piccardo, J.C. Manson, and N.M. Hooper Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and swedish mutant amyloid precursor protein J. Biol. Chem. 286 2011 33489 33500
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 33489-33500
-
-
Griffiths, H.H.1
Whitehouse, I.J.2
Baybutt, H.3
Brown, D.4
Kellett, K.A.5
Jackson, C.D.6
Turner, A.J.7
Piccardo, P.8
Manson, J.C.9
Hooper, N.M.10
-
24
-
-
24944491725
-
Copper binding is the governing determinant of prion protein turnover
-
C.L. Haigh, K. Edwards, and D.R. Brown Copper binding is the governing determinant of prion protein turnover Mol. Cell. Neurosci. 30 2005 186 196
-
(2005)
Mol. Cell. Neurosci.
, vol.30
, pp. 186-196
-
-
Haigh, C.L.1
Edwards, K.2
Brown, D.R.3
-
25
-
-
65549119787
-
Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production
-
S.E. Hoey, R.J. Williams, and M.S. Perkinton Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production J. Neurosci. 29 2009 4442 4460
-
(2009)
J. Neurosci.
, vol.29
, pp. 4442-4460
-
-
Hoey, S.E.1
Williams, R.J.2
Perkinton, M.S.3
-
26
-
-
0042381229
-
A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation
-
A. Holme, M. Daniels, J. Sassoon, and D.R. Brown A novel method of generating neuronal cell lines from gene-knockout mice to study prion protein membrane orientation Eur. J. Neurosci. 18 2003 571 579
-
(2003)
Eur. J. Neurosci.
, vol.18
, pp. 571-579
-
-
Holme, A.1
Daniels, M.2
Sassoon, J.3
Brown, D.R.4
-
27
-
-
38749114643
-
Determining thermodynamic parameters from isothermal calorimetric isotherms of the binding of macromolecules to metal cations originally chelated by a weak ligand
-
L. Hong, W.D. Bush, L.Q. Hatcher, and J. Simon Determining thermodynamic parameters from isothermal calorimetric isotherms of the binding of macromolecules to metal cations originally chelated by a weak ligand J. Phys. Chem. B 112 2008 604 611
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 604-611
-
-
Hong, L.1
Bush, W.D.2
Hatcher, L.Q.3
Simon, J.4
-
28
-
-
67650299008
-
Binding of Cu(II) to human alpha-synucleins: Comparison of wild type and the point mutations associated with the familial Parkinson's disease
-
L. Hong, and J.D. Simon Binding of Cu(II) to human alpha-synucleins: comparison of wild type and the point mutations associated with the familial Parkinson's disease J. Phys. Chem. B 113 2009 9551 9561
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 9551-9561
-
-
Hong, L.1
Simon, J.D.2
-
29
-
-
0034333041
-
In search of an enzyme: The beta-secretase of Alzheimer's disease is an aspartic proteinase
-
D.R. Howlett, D.L. Simmons, C. Dingwall, and G. Christie In search of an enzyme: the beta-secretase of Alzheimer's disease is an aspartic proteinase Trends Neurosci. 23 2000 565 570
-
(2000)
Trends Neurosci.
, vol.23
, pp. 565-570
-
-
Howlett, D.R.1
Simmons, D.L.2
Dingwall, C.3
Christie, G.4
-
30
-
-
80054905533
-
A novel PrP partner HS-1 associated protein X-1 (HAX-1) protected the cultured cells against the challenge of H(2)O(2)
-
Y.Y. Jing, X.L. Li, Q. Shi, Z.Y. Wang, Y. Guo, M.M. Pan, C. Tian, S.Y. Zhu, C. Chen, H.S. Gong, J. Han, C. Gao, and X.P. Dong A novel PrP partner HS-1 associated protein X-1 (HAX-1) protected the cultured cells against the challenge of H(2)O(2) J. Mol. Neurosci. 2011
-
(2011)
J. Mol. Neurosci.
-
-
Jing, Y.Y.1
Li, X.L.2
Shi, Q.3
Wang, Z.Y.4
Guo, Y.5
Pan, M.M.6
Tian, C.7
Zhu, S.Y.8
Chen, C.9
Gong, H.S.10
Han, J.11
Gao, C.12
Dong, X.P.13
-
32
-
-
67349103914
-
The effects of prion protein expression on metal metabolism
-
S. Kralovicova, S.N. Fontaine, A. Alderton, J. Alderman, K.V. Ragnarsdottir, S.J. Collins, and D.R. Brown The effects of prion protein expression on metal metabolism Mol. Cell. Neurosci. 41 2009 135 147
-
(2009)
Mol. Cell. Neurosci.
, vol.41
, pp. 135-147
-
-
Kralovicova, S.1
Fontaine, S.N.2
Alderton, A.3
Alderman, J.4
Ragnarsdottir, K.V.5
Collins, S.J.6
Brown, D.R.7
-
33
-
-
0038730534
-
Cloning and expression of the rat BACE1 promoter
-
C. Lange-Dohna, U. Zeitschel, F. Gaunitz, J.R. Perez-Polo, V. Bigl, and S. Rossner Cloning and expression of the rat BACE1 promoter J. Neurosci. Res. 73 2003 73 80
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 73-80
-
-
Lange-Dohna, C.1
Zeitschel, U.2
Gaunitz, F.3
Perez-Polo, J.R.4
Bigl, V.5
Rossner, S.6
-
34
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
-
J. Lauren, D.A. Gimbel, H.B. Nygaard, J.W. Gilbert, and S.M. Strittmatter Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers Nature 457 2009 1128 1132
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
35
-
-
34547400403
-
Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein
-
E.T. Parkin, N.T. Watt, I. Hussain, E.A. Eckman, C.B. Eckman, J.C. Manson, H.N. Baybutt, A.J. Turner, and N.M. Hooper Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein Proc. Natl. Acad. Sci. USA 104 2007 11062 11067
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11062-11067
-
-
Parkin, E.T.1
Watt, N.T.2
Hussain, I.3
Eckman, E.A.4
Eckman, C.B.5
Manson, J.C.6
Baybutt, H.N.7
Turner, A.J.8
Hooper, N.M.9
-
36
-
-
42549136005
-
LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein
-
C.J. Parkyn, E.G. Vermeulen, R.C. Mootoosamy, C. Sunyach, C. Jacobsen, C. Oxvig, S. Moestrup, Q. Liu, G. Bu, A. Jen, and R.J. Morris LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein J. Cell Sci. 121 2008 773 783
-
(2008)
J. Cell Sci.
, vol.121
, pp. 773-783
-
-
Parkyn, C.J.1
Vermeulen, E.G.2
Mootoosamy, R.C.3
Sunyach, C.4
Jacobsen, C.5
Oxvig, C.6
Moestrup, S.7
Liu, Q.8
Bu, G.9
Jen, A.10
Morris, R.J.11
-
38
-
-
0031866162
-
Cellular prion protein localization in rodent and primate brain
-
N. Sales, K. Rodolfo, R. Hassig, B. Faucheux, L. Di Giamberardino, and K.L. Moya Cellular prion protein localization in rodent and primate brain Eur. J. Neurosci. 10 1998 2464 2471
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 2464-2471
-
-
Sales, N.1
Rodolfo, K.2
Hassig, R.3
Faucheux, B.4
Di Giamberardino, L.5
Moya, K.L.6
-
39
-
-
80052149544
-
ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1
-
R. Sannerud, I. Declerck, A. Peric, T. Raemaekers, G. Menendez, L. Zhou, B. Veerle, K. Coen, S. Munck, B. De Strooper, G. Schiavo, and W. Annaert ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1 Proc. Natl. Acad. Sci. USA 108 2011 E559 E568
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
-
-
Sannerud, R.1
Declerck, I.2
Peric, A.3
Raemaekers, T.4
Menendez, G.5
Zhou, L.6
Veerle, B.7
Coen, K.8
Munck, S.9
De Strooper, B.10
Schiavo, G.11
Annaert, W.12
-
42
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
R.E. Tanzi, and L. Bertram Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective Cell 120 2005 545 555
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
43
-
-
33751108289
-
The affinity of copper binding to the prion protein octarepeat domain: Evidence for negative cooperativity
-
E.D. Walter, M. Chattopadhyay, and G.L. Millhauser The affinity of copper binding to the prion protein octarepeat domain: evidence for negative cooperativity Biochemistry 45 2006 13083 13092
-
(2006)
Biochemistry
, vol.45
, pp. 13083-13092
-
-
Walter, E.D.1
Chattopadhyay, M.2
Millhauser, G.L.3
|