메뉴 건너뛰기




Volumn 10, Issue 9, 2012, Pages 1189-1202

The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment

Author keywords

[No Author keywords available]

Indexed keywords

EPIRUBICIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN FOXM1; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

EID: 84866497672     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-11-0559     Document Type: Article
Times cited : (48)

References (46)
  • 1
    • 84866516952 scopus 로고    scopus 로고
    • Cancer Research UK. CRUK Press, London UK
    • Cancer Research UK. Cancer Stats report-Breast Cancer UK. CRUK Press, London UK; 2011.
    • (2011) Cancer Stats Report-Breast Cancer UK
  • 2
    • 77953585301 scopus 로고    scopus 로고
    • Overcoming taxane and anthracycline resistance
    • Zelnak A. Overcoming taxane and anthracycline resistance. Breast J 2010;16:309-12.
    • (2010) Breast J , vol.16 , pp. 309-312
    • Zelnak, A.1
  • 3
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004;56:185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 5
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases: A molecular perspective
    • Wang JC. Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol 2002;3:430-40.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 430-440
    • Wang, J.C.1
  • 6
    • 70350243205 scopus 로고    scopus 로고
    • Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance
    • Zhu Y, Hu J, Hu Y, Liu W. Targeting DNA repair pathways: a novel approach to reduce cancer therapeutic resistance. Cancer Treat Rev 2009;35:590-6.
    • (2009) Cancer Treat Rev , vol.35 , pp. 590-596
    • Zhu, Y.1    Hu, J.2    Hu, Y.3    Liu, W.4
  • 8
    • 77953579968 scopus 로고    scopus 로고
    • Implications of anthracycline-resistant and taxane-resistant metastatic breast cancer and new therapeutic options
    • Rivera E. Implications of anthracycline-resistant and taxane-resistant metastatic breast cancer and new therapeutic options. Breast J 2010;16:252-63.
    • (2010) Breast J , vol.16 , pp. 252-263
    • Rivera, E.1
  • 9
    • 35548930209 scopus 로고    scopus 로고
    • The emerging roles of forkhead box (Fox) proteins in cancer
    • Myatt SS, Lam EW. The emerging roles of forkhead box (Fox) proteins in cancer. Nat Rev Cancer 2007;7:847-59.
    • (2007) Nat Rev Cancer , vol.7 , pp. 847-859
    • Myatt, S.S.1    Lam, E.W.2
  • 12
    • 7544231164 scopus 로고    scopus 로고
    • Themouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during livermorphogenesis
    • Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, et al. Themouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during livermorphogenesis. Dev Biol 2004;276:74-88.
    • (2004) Dev Biol , vol.276 , pp. 74-88
    • Krupczak-Hollis, K.1    Wang, X.2    Kalinichenko, V.V.3    Gusarova, G.A.4    Wang, I.C.5    Dennewitz, M.B.6
  • 13
    • 0030786320 scopus 로고    scopus 로고
    • The winged-helix transcription factor Trident is expressed in cycling cells
    • Korver W, Roose J, Clevers H. The winged-helix transcription factor Trident is expressed in cycling cells. Nucleic Acids Res 1997;25:1715-9.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1715-1719
    • Korver, W.1    Roose, J.2    Clevers, H.3
  • 14
    • 1642382817 scopus 로고    scopus 로고
    • Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators
    • Major ML, Lepe R, Costa RH. Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators. Mol Cell Biol 2004;24:2649-61.
    • (2004) Mol Cell Biol , vol.24 , pp. 2649-2661
    • Major, M.L.1    Lepe, R.2    Costa, R.H.3
  • 15
    • 14944357408 scopus 로고    scopus 로고
    • Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c
    • Ma RY, Tong TH, Cheung AM, Tsang AC, Leung WY, Yao KM. Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c. J Cell Sci 2005;118:795-806.
    • (2005) J Cell Sci , vol.118 , pp. 795-806
    • Ma, R.Y.1    Tong, T.H.2    Cheung, A.M.3    Tsang, A.C.4    Leung, W.Y.5    Yao, K.M.6
  • 16
    • 42349091078 scopus 로고    scopus 로고
    • Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain
    • Laoukili J, Alvarez M, Meijer LA, Stahl M, Mohammed S, Kleij L, et al. Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. Mol Cell Biol 2008;28:3076-87.
    • (2008) Mol Cell Biol , vol.28 , pp. 3076-3087
    • Laoukili, J.1    Alvarez, M.2    Meijer, L.A.3    Stahl, M.4    Mohammed, S.5    Kleij, L.6
  • 17
    • 33846619711 scopus 로고    scopus 로고
    • Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
    • Tan Y, Raychaudhuri P, Costa RH. Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes. Mol Cell Biol 2007;27:1007-16.
    • (2007) Mol Cell Biol , vol.27 , pp. 1007-1016
    • Tan, Y.1    Raychaudhuri, P.2    Costa, R.H.3
  • 18
    • 11144353897 scopus 로고    scopus 로고
    • Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF 774tumor suppressor
    • Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM, et al. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF 774tumor suppressor. Genes Dev 2004;18:830-50.
    • (2004) Genes Dev , vol.18 , pp. 830-850
    • Kalinichenko, V.V.1    Major, M.L.2    Wang, X.3    Petrovic, V.4    Kuechle, J.5    Yoder, H.M.6
  • 19
    • 32944459113 scopus 로고    scopus 로고
    • Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
    • Kalin TV, Wang IC, Ackerson TJ, Major ML, Detrisac CJ, Kalinichenko VV, et al. Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res 2006;66:1712-20.
    • (2006) Cancer Res , vol.66 , pp. 1712-1720
    • Kalin, T.V.1    Wang, I.C.2    Ackerson, T.J.3    Major, M.L.4    Detrisac, C.J.5    Kalinichenko, V.V.6
  • 20
    • 33644542405 scopus 로고    scopus 로고
    • The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
    • Kim IM, Ackerson T, Ramakrishna S, Tretiakova M, Wang IC, Kalin TV, et al. The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res 2006;66:2153-61.
    • (2006) Cancer Res , vol.66 , pp. 2153-2161
    • Kim, I.M.1    Ackerson, T.2    Ramakrishna, S.3    Tretiakova, M.4    Wang, I.C.5    Kalin, T.V.6
  • 21
    • 34247221487 scopus 로고    scopus 로고
    • The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer
    • Yoshida Y, Wang IC, Yoder HM, Davidson NO, Costa RH. The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer. Gastroenterology 2007;132:1420-31.
    • (2007) Gastroenterology , vol.132 , pp. 1420-1431
    • Yoshida, Y.1    Wang, I.C.2    Yoder, H.M.3    Davidson, N.O.4    Costa, R.H.5
  • 22
  • 24
    • 79958699243 scopus 로고    scopus 로고
    • ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance
    • Millour J, de Olano N, Horimoto Y, Monteiro LJ, Langer JK, Aligue R, et al. ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance. Mol Cancer Ther 2011;10:1046-58.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1046-1058
    • Millour, J.1    De Olano, N.2    Horimoto, Y.3    Monteiro, L.J.4    Langer, J.K.5    Aligue, R.6
  • 25
    • 31544445749 scopus 로고    scopus 로고
    • Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells ismediated by c-Jun NH2-terminal kinase and Akt
    • Sunters A, Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, et al. Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells ismediated by c-Jun NH2-terminal kinase and Akt. Cancer Res 2006;66:212-20.
    • (2006) Cancer Res , vol.66 , pp. 212-220
    • Sunters, A.1    Madureira, P.A.2    Pomeranz, K.M.3    Aubert, M.4    Brosens, J.J.5    Cook, S.J.6
  • 26
    • 73249143312 scopus 로고    scopus 로고
    • Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration
    • Menon MB, Ronkina N, Schwermann J, Kotlyarov A, Gaestel M. Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration. Cell Motil Cytoskeleton 2009;66:1041-7.
    • (2009) Cell Motil Cytoskeleton , vol.66 , pp. 1041-1047
    • Menon, M.B.1    Ronkina, N.2    Schwermann, J.3    Kotlyarov, A.4    Gaestel, M.5
  • 27
    • 37549005218 scopus 로고    scopus 로고
    • The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells
    • Krol J, Francis RE, Albergaria A, Sunters A, Polychronis A, Coombes RC, et al. The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells. Mol Cancer Ther 2007;6:3169-79.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3169-3179
    • Krol, J.1    Francis, R.E.2    Albergaria, A.3    Sunters, A.4    Polychronis, A.5    Coombes, R.C.6
  • 28
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh JK, Fredersdorf S, Kouzarides T, Martin K, Lu X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev 1997;11:1840-52.
    • (1997) Genes Dev , vol.11 , pp. 1840-1852
    • Hsieh, J.K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 29
    • 0028875318 scopus 로고
    • Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
    • Engel K, Schultz H, Martin F, Kotlyarov A, Plath K, Hahn M, et al. Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif. J Biol Chem 1995;270:27213-21.
    • (1995) J Biol Chem , vol.270 , pp. 27213-27221
    • Engel, K.1    Schultz, H.2    Martin, F.3    Kotlyarov, A.4    Plath, K.5    Hahn, M.6
  • 30
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, et al. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 1999;18:4969-80.
    • (1999) EMBO J , vol.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.Y.5    Shyu, A.B.6
  • 31
    • 0038752083 scopus 로고    scopus 로고
    • Chk2 activates E2F-1 in response to DNA damage
    • Stevens C, Smith L, La Thangue NB. Chk2 activates E2F-1 in response to DNA damage. Nat Cell Biol 2003;5:401-9.
    • (2003) Nat Cell Biol , vol.5 , pp. 401-409
    • Stevens, C.1    Smith, L.2    La Thangue, N.B.3
  • 32
    • 47749107973 scopus 로고    scopus 로고
    • Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein
    • Paleologou KE, Schmid AW, Rospigliosi CC, Kim HY, Lamberto GR, Fredenburg RA, et al. Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem 2008;283:16895-905.
    • (2008) J Biol Chem , vol.283 , pp. 16895-16905
    • Paleologou, K.E.1    Schmid, A.W.2    Rospigliosi, C.C.3    Kim, H.Y.4    Lamberto, G.R.5    Fredenburg, R.A.6
  • 33
    • 34447315523 scopus 로고    scopus 로고
    • Setting the stage for S phase
    • Wilson AC. Setting the stage for S phase. Mol Cell 2007;27:176-7.
    • (2007) Mol Cell , vol.27 , pp. 176-177
    • Wilson, A.C.1
  • 34
    • 18344393150 scopus 로고    scopus 로고
    • The E2F transcriptional network: Old acquaintances with new faces
    • Dimova DK, Dyson NJ. The E2F transcriptional network: old acquaintances with new faces. Oncogene 2005;24:2810-26.
    • (2005) Oncogene , vol.24 , pp. 2810-2826
    • Dimova, D.K.1    Dyson, N.J.2
  • 35
    • 54049120956 scopus 로고    scopus 로고
    • E2F - At the crossroads of life and death
    • Polager S, Ginsberg D. E2F - at the crossroads of life and death. Trends Cell Biol 2008;18:528-35.
    • (2008) Trends Cell Biol , vol.18 , pp. 528-535
    • Polager, S.1    Ginsberg, D.2
  • 36
    • 33646047403 scopus 로고    scopus 로고
    • E2F1-induced apoptosis: Turning killers into therapeutics
    • Stanelle J, Putzer BM. E2F1-induced apoptosis: turning killers into therapeutics. Trends Mol Med 2006;12:177-85.
    • (2006) Trends Mol Med , vol.12 , pp. 177-185
    • Stanelle, J.1    Putzer, B.M.2
  • 37
    • 71349084149 scopus 로고    scopus 로고
    • Pro-proliferative FoxM1 is a target of p53-mediated repression
    • Barsotti AM, Prives C. Pro-proliferative FoxM1 is a target of p53-mediated repression. Oncogene 2009;28:4295-305.
    • (2009) Oncogene , vol.28 , pp. 4295-4305
    • Barsotti, A.M.1    Prives, C.2
  • 38
    • 77953529864 scopus 로고    scopus 로고
    • E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair
    • Guo R, Chen J, Zhu F, Biswas AK, Berton TR, Mitchell DL, et al. E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair. J Biol Chem 2010;285:19308-15.
    • (2010) J Biol Chem , vol.285 , pp. 19308-19315
    • Guo, R.1    Chen, J.2    Zhu, F.3    Biswas, A.K.4    Berton, T.R.5    Mitchell, D.L.6
  • 39
    • 0345299171 scopus 로고    scopus 로고
    • Increased levels of E2F-1-dependent DNA binding activity after UV- Or gamma-irradiation
    • Hofferer M, Wirbelauer C, Humar B, Krek W. Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res 1999;27:491-5.
    • (1999) Nucleic Acids Res , vol.27 , pp. 491-495
    • Hofferer, M.1    Wirbelauer, C.2    Humar, B.3    Krek, W.4
  • 40
    • 79954554211 scopus 로고    scopus 로고
    • E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks
    • Chen J, Zhu F, Weaks RL, Biswas AK, Guo R, Li Y, et al. E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks. Cell Cycle 2011;10:1287-94.
    • (2011) Cell Cycle , vol.10 , pp. 1287-1294
    • Chen, J.1    Zhu, F.2    Weaks, R.L.3    Biswas, A.K.4    Guo, R.5    Li, Y.6
  • 41
    • 58149359240 scopus 로고    scopus 로고
    • Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation
    • Ivanova IA, Nakrieko KA, Dagnino L. Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation. Oncogene 2009;28:52-62.
    • (2009) Oncogene , vol.28 , pp. 52-62
    • Ivanova, I.A.1    Nakrieko, K.A.2    Dagnino, L.3
  • 43
    • 79551622682 scopus 로고    scopus 로고
    • p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis
    • Delston RB, Matatall KA, Sun Y, Onken MD, Harbour JW. p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis. Oncogene 2011;30:588-99.
    • (2011) Oncogene , vol.30 , pp. 588-599
    • Delston, R.B.1    Matatall, K.A.2    Sun, Y.3    Onken, M.D.4    Harbour, J.W.5
  • 45
    • 27944478688 scopus 로고    scopus 로고
    • Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway
    • Zhang Z, Wang H, Li M, Rayburn ER, Agrawal S, Zhang R. Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway. Oncogene 2005;24:7238-47.
    • (2005) Oncogene , vol.24 , pp. 7238-7247
    • Zhang, Z.1    Wang, H.2    Li, M.3    Rayburn, E.R.4    Agrawal, S.5    Zhang, R.6
  • 46
    • 0033559703 scopus 로고    scopus 로고
    • Regulation of Rb and E2F by signal transduction cascades: Divergent effects of JNK1 and p38 kinases
    • Wang S, Nath N, Minden A, Chellappan S. Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases. EMBO J 1999;18:1559-70.
    • (1999) EMBO J , vol.18 , pp. 1559-1570
    • Wang, S.1    Nath, N.2    Minden, A.3    Chellappan, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.