Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 8, 2004, Pages 2392-2397

  López Rodríguez, Cristina ^a,e   Antos, Christopher L ^b,f   Shelton, John M ^c   Richardson, James A ^b,c   Lin, Fangming ^c   Novobrantseva, Tatiana I ^a   Bronson, Roderick T ^d   Igarashi, Peter ^c   Rao, Anjana ^a   Olson, Eric N ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d TUFTS UNIVERSITY   (United States)

^e CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^f MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RAS PROTEIN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ALDOSE REDUCTASE GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATROPHY; CELL ACTIVITY; CELL MIGRATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; ENHANCER REGION; FIBROBLAST; GENE EXPRESSION REGULATION; GENE MUTATION; HOMEOSTASIS; HOMOZYGOSITY; KIDNEY ATROPHY; KIDNEY DEVELOPMENT; KIDNEY FUNCTION; MOUSE; NONHUMAN; NULL ALLELE; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; REGULATOR GENE; STRESS; T LYMPHOCYTE ACTIVATION; TONICITY RESPONSIVE ENHANCER GENE; TRANSCRIPTION REGULATION;

ANIMALS; ATROPHY; DNA-BINDING PROTEINS; EXONS; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; KIDNEY; KIDNEY DISEASES; MICE; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 4644333445     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308703100     Document Type: Article

References (24)

1. Burg, M., Kwon, E. & Kultz, D. (1997) Annu. Rev. Physiol. 59, 437-455.
2. Haussinger, D. (1996) Biochem. J. 313, 697-710.
3. Kwon, H. M. & Handler, J. S. (1995) Curr. Opin. Cell Biol. 7, 465-471.
4. Guyton, A. C. & Hall, J. E. (1996) in Textbook of Medical Physiology (Saunders, Philadelphia), pp. 349-366.
5. López-Rodríguez, C., Aramburu, J., Rakeman, A. S. & Rao, A. (1999) Proc. Natl. Acad. Sci. USA 96, 7214-7219.
6. Graef, I. A., Gastier, J. M., Francke, U. & Crabtree, G. R. (2001) Proc. Natl. Acad. Sci. USA 98, 5740-5745.
7. López-Rodríguez, C., Aramburu, J., Rakeman, A. S., Copeland, N. G., Gilbert, D. J., Thomas, S., Disteche, C., Jenkins, N. A. & Rao, A. (1999) Cold Spring Harbor Symp. Quant. Biol. 64, 517-526.
8. Stroud, J. C., López-Rodríguez, C., Rao, A. & Chen, L. (2002) Nat. Struct. Biol. 9, 90-94.
9. Miyakawa, H., Woo, S. K., Dahl, S. C., Handler, J. S. & Kwon, H. M. (1999) Proc. Natl. Acad. Sci. USA. 96, 2538-2542.
10. Woo, S. K., Lee, S. D. & Kwon H. M. (2002) Pflügers Arch. Eur. J. Physiol. 444, 579-585.
11. Lopez-Rodriguez, C., Aramburu, J., Jin, L., Rakeman, A. S., Michino, M. & Rao, A. (2001) Immunity 15, 47-58.
12. Cha, J. H., Woo, S. K., Han, K. H., Kim, Y. H., Handler, J. S., Kim, J. & Kwon, H. M. (2001) J. Am. Soc. Nephrol. 12, 2221-2230.
13. Trama, J., Lu, Q., Hawley, R. G. & Ho, S. N. (2000) J. Immunol. 165, 4884-4894.
14. Jauliac, S., López-Rodríguez, C., Shaw, L. M., Brown, L. F., Rao, A. & Toker, A. (2002) Nat. Cell. Biol. 4, 540-544.
15. Huang, A. M. & Rubin, G. M. (2000) Genetics 156, 1219-1230.
16. Fernandez-Llama, P., Andrews, P., Ecelbarger, C. A., Nielsen, S. & Knepper, M. (1998) Kidney Int. 54, 170-179.
17. Shelton, J. M., Lee, M. H., Richardson, J. A. & Patel, S. B. (2000) J. Lipid Res. 41, 532-537.
18. Conner, D. A. (2000) in Current Protocols in Molecular Biology, eds. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J., Smith, J. A. & Struhl, K. (Wiley, Hoboken, N.J.), pp. 23.2.1-23.2.7.
19. Ko, B. C. B., Ruepp, B., Bohren, K. M., Gabbay, K. H. & Chung, S. S. M. (1997) J. Biol. Chem. 272, 16431-16437.
20. Michea, L., Ferguson, D. R., Peters, E. M., Andrews, P. M., Kirby, M. R. & Burg, M. B. (2000) Am. J. Physiol. 278, F209-F218.
21. Dressler, G. R., Wilkinson, J. E., Rothenpieler, U. W., Patterson, L. T., Williams-Simons, L. & Westphal, H. (1993) Nature 362, 65-67.
22. Yang, B., Gillespie, A., Carlson, E. J., Epstein, C. J. & Verkman, A. S. (2001) J. Biol. Chem. 276, 2775-2779.
23. Kitamura, H., Yamauchi, A., Sugiura, T., Matsuoka, Y., Horio, M., Tohyama, M., Shimada, S., Imari, E. & Hori, M. (1998) Kidney Int. 53, 146-153.
24. Aida, K., Ikegishi, Y., Chen, J., Tawata, M., Ito, S., Maeda, S. & Onaya, T. (2000) Biochem. Biophys. Res. Commun. 277, 281-286.