Key role of nuclear factor-κB in the cellular pharmacokinetics of adriamycin in MCF-7/Adr cells: The potential mechanism for synergy with 20(S)-ginsenoside Rh2

Drug Metabolism and Disposition

Volumn 40, Issue 10, 2012, Pages 1900-1908

  Zhang, Jingwei ^a   Lu, Meng ^a   Zhou, Fang ^a   Sun, Haopeng ^a   Hao, Gang ^a   Wu, Xiaolan ^a   Wang, Guangji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; GINSENOSIDE RH 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE PROTEIN 1;

ARTICLE; BINDING AFFINITY; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BINDING SITES; BREAST NEOPLASMS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GINSENOSIDES; HUMANS; I-KAPPA B KINASE; MCF-7 CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P-GLYCOPROTEIN; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 84866455447     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.045187     Document Type: Article

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