메뉴 건너뛰기




Volumn 49, Issue 2, 2011, Pages 132-142

Doxorubicin induces drug efflux pumps in Candida albicans

Author keywords

ABC transporter; azoles; Candida albicans; doxorubicin; resistance mechanisms

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; FLUCONAZOLE; MESSENGER RNA;

EID: 78751504435     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693786.2010.512022     Document Type: Article
Times cited : (18)

References (33)
  • 1
    • 0032801225 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in United States hospitals: A three-year analysis
    • Edmond MB, Wallace SE, McClish DK, et al. Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis 1999; 29 : 239-244.
    • (1999) Clin Infect Dis , vol.29 , pp. 239-244
    • Edmond, M.B.1    Wallace, S.E.2    McClish, D.K.3
  • 2
    • 0031899916 scopus 로고    scopus 로고
    • National surveillance of nosocomial blood stream infection due to Candida albicans: Frequency of occurrence and antifungal susceptibility in the SCOPE Program
    • Pfaller MA, Jones RN, Messer SA, Edmond MB, Wenzel RP. National surveillance of nosocomial blood stream infection due to Candida albicans : frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn Microbiol Infect Dis 1998; 31 : 327-332.
    • (1998) Diagn Microbiol Infect Dis , vol.31 , pp. 327-332
    • Pfaller, M.A.1    Jones, R.N.2    Messer, S.A.3    Edmond, M.B.4    Wenzel, R.P.5
  • 3
    • 3943093972 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in US hospitals: Analysis of 24,179 cases from a prospective nationwide surveillance study
    • Wisplinghoff H, Bischoff T, Tallent SM, et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004; 39 : 309-317.
    • (2004) Clin Infect Dis , vol.39 , pp. 309-317
    • Wisplinghoff, H.1    Bischoff, T.2    Tallent, S.M.3
  • 4
    • 0242659142 scopus 로고    scopus 로고
    • Attributable mortality of nosocomial candidemia, revisited
    • Gudlaugsson O, Gillespie S, Lee K, et al. Attributable mortality of nosocomial candidemia, revisited. Clin Infect Dis 2003; 37 : 1172-1177.
    • (2003) Clin Infect Dis , vol.37 , pp. 1172-1177
    • Gudlaugsson, O.1    Gillespie, S.2    Lee, K.3
  • 5
    • 0032953377 scopus 로고    scopus 로고
    • Candidemia in cancer patients: A prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC)
    • Viscoli C, Girmenia C, Marinus A, et al. Candidemia in cancer patients: a prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC). Clin Infect Dis 1999; 1071-1079
    • (1999) Clin Infect Dis , pp. 1071-1079
    • Viscoli, C.1    Girmenia, C.2    Marinus, A.3
  • 6
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • White TC, Marr KA, Bowden RA. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev 1998; 11 : 382-402.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 382-402
    • White, T.C.1    Marr, K.A.2    Bowden, R.A.3
  • 7
    • 0028793725 scopus 로고
    • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specifi c multidrug transporters
    • Sanglard D, Kuchler K, Ischer F, et al. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specifi c multidrug transporters. Antimicrob Agents Chemother 1995; 39 : 2378-2386.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2378-2386
    • Sanglard, D.1    Kuchler, K.2    Ischer, F.3
  • 8
    • 0043270593 scopus 로고    scopus 로고
    • C andida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents
    • Sanglard D, Ischer F, Parkinson T, Falconer D, Bille J. C andida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents. Antimicrob Agents Chemother 2003; 47 : 2404-2412.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2404-2412
    • Sanglard, D.1    Ischer, F.2    Parkinson, T.3    Falconer, D.4    Bille, J.5
  • 9
    • 0031759244 scopus 로고    scopus 로고
    • Multiple molecular mechanisms contribute to a stepwise development of fl uconazole resistance in clinical Candida albicans strains
    • Franz R, Kelly SL, Lamb DC, et al. Multiple molecular mechanisms contribute to a stepwise development of fl uconazole resistance in clinical Candida albicans strains. Antimicrob Agents Chemother 1998; 42 : 3065-3072.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3065-3072
    • Franz, R.1    Kelly, S.L.2    Lamb, D.C.3
  • 11
    • 23844521998 scopus 로고    scopus 로고
    • P-glycoprotein-implications of metabolism of neoplastic cells and cancer therapy
    • Breier A, Barancik M, Sulova Z, Uhrik B. P-glycoprotein-implications of metabolism of neoplastic cells and cancer therapy. Curr Cancer Drug Targets 2005; 5 : 457-468.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 457-468
    • Breier, A.1    Barancik, M.2    Sulova, Z.3    Uhrik, B.4
  • 12
    • 23844481408 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in cancer chemotherapy
    • Luqmani YA. Mechanisms of drug resistance in cancer chemotherapy. Med Princ Pract 2005; 14 (Suppl. 1): 35-48.
    • (2005) Med Princ Pract , vol.14 , Issue.SUPPL. 1 , pp. 35-48
    • Luqmani, Y.A.1
  • 13
    • 0025477701 scopus 로고
    • Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells
    • Chin KV, Chauhan SS, Pastan I, Gottesman MM. Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells. Cell Growth Differ 1990; 1 : 361-365.
    • (1990) Cell Growth Differ , vol.1 , pp. 361-365
    • Chin, K.V.1    Chauhan, S.S.2    Pastan, I.3    Gottesman, M.M.4
  • 14
    • 34250331903 scopus 로고    scopus 로고
    • Transporter-mediated drug interactions: Clinical implications and in vitro assessment
    • Lin JH. Transporter-mediated drug interactions: clinical implications and in vitro assessment. Expert Opin Drug Metab Toxicol 2007; 3 : 81-92.
    • (2007) Expert Opin Drug Metab Toxicol , vol.3 , pp. 81-92
    • Lin, J.H.1
  • 15
    • 33846020948 scopus 로고    scopus 로고
    • Development of a new real-time TaqMan PCR assay for quantitative analyses of Candida albicans resistance genes expression
    • Kofl a G, Ruhnke M. Development of a new real-time TaqMan PCR assay for quantitative analyses of Candida albicans resistance genes expression. J Microbiol Methods 2007; 68 : 178-183.
    • (2007) J Microbiol Methods , vol.68 , pp. 178-183
    • Kofla, G.1    Ruhnke, M.2
  • 16
    • 11144270183 scopus 로고    scopus 로고
    • TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2
    • Coste AT, Karababa M, Ischer F, Bille J, Sanglard D. TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot Cell 2004; 3 : 1639-1652.
    • (2004) Eukaryot Cell , vol.3 , pp. 1639-1652
    • Coste, A.T.1    Karababa, M.2    Ischer, F.3    Bille, J.4    Sanglard, D.5
  • 17
    • 33846025066 scopus 로고    scopus 로고
    • Identifi cation of promoter elements responsible for the regulation of MDR1 from Candida albicans , a major facilitator transporter involved in azole resistance
    • Rognon B, Kozovska Z, Coste AT, Pardini G, Sanglard D. Identifi cation of promoter elements responsible for the regulation of MDR1 from Candida albicans , a major facilitator transporter involved in azole resistance. Microbiology 2006; 152 : 3701-3722.
    • (2006) Microbiology , vol.152 , pp. 3701-3722
    • Rognon, B.1    Kozovska, Z.2    Coste, A.T.3    Pardini, G.4    Sanglard, D.5
  • 18
    • 0032888237 scopus 로고    scopus 로고
    • Molecular aspects of fl uconazole resistance development in Candida albicans
    • Franz R, Ruhnke M, Morschh?user J. Molecular aspects of fl uconazole resistance development in Candida albicans . Mycoses 1999; 42 : 453-458.
    • (1999) Mycoses , vol.42 , pp. 453-458
    • Franz, R.1    Ruhnke, M.2    Morschhuser, J.3
  • 19
    • 0034758558 scopus 로고    scopus 로고
    • Antifungal susceptibility testing: Practical aspects and current challenges
    • Rex JH, Pfaller MA, Walsh TJ, et al. Antifungal susceptibility testing: practical aspects and current challenges. Clin Microbiol Rev 2001; 14 : 643-658.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 643-658
    • Rex, J.H.1    Pfaller, M.A.2    Walsh, T.J.3
  • 20
    • 33846025066 scopus 로고    scopus 로고
    • Identifi cation of promoter elements responsible for the regulation of MDR1 from Candida albicans , a major facilitator transporter involved in azole resistance
    • Rognon B, Kozovska Z, Coste AT, Pardini G, Sanglard D. Identifi cation of promoter elements responsible for the regulation of MDR1 from Candida albicans , a major facilitator transporter involved in azole resistance. Microbiology 2006; 152 : 3701-3722.
    • (2006) Microbiology , vol.152 , pp. 3701-3722
    • Rognon, B.1    Kozovska, Z.2    Coste, A.T.3    Pardini, G.4    Sanglard, D.5
  • 21
    • 0035020715 scopus 로고    scopus 로고
    • Development of S treptococcus thermophilus lacZ as a reporter gene for Candida albicans
    • Uhl MA, Johnson AD. Development of S treptococcus thermophilus lacZ as a reporter gene for Candida albicans . Microbiology 2001; 1189-1195.
    • (2001) Microbiology , pp. 1189-1195
    • Uhl, M.A.1    Johnson, A.D.2
  • 22
    • 33646171879 scopus 로고    scopus 로고
    • A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
    • Coste A, Turner V, Ischer F, et al. A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans . Genetics 2006; 172 : 2139-2156.
    • (2006) Genetics , vol.172 , pp. 2139-2156
    • Coste, A.1    Turner, V.2    Ischer, F.3
  • 23
    • 33845968175 scopus 로고    scopus 로고
    • The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans
    • Pardini G, De Groot PW, Coste AT, et al. The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans . J Biol Chem 2006; 281 : 40399-40411.
    • (2006) J Biol Chem , vol.281 , pp. 40399-40411
    • Pardini, G.1    De Groot, P.W.2    Coste, A.T.3
  • 24
    • 3342996550 scopus 로고    scopus 로고
    • Comparison of gene expression profi les of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters
    • Karababa M, Coste AT, Rognon B, Bille J, Sanglard D. Comparison of gene expression profi les of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob Agents Chemother 2004; 48 : 3064-3079.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3064-3079
    • Karababa, M.1    Coste, A.T.2    Rognon, B.3    Bille, J.4    Sanglard, D.5
  • 26
    • 0036223414 scopus 로고    scopus 로고
    • A common drugresponsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance
    • de Micheli M, Bille J, Schueller C, Sanglard D. A common drugresponsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance. Mol Microbiol 2002; 43 : 1197-1214.
    • (2002) Mol Microbiol , vol.43 , pp. 1197-1214
    • De Micheli, M.1    Bille, J.2    Schueller, C.3    Sanglard, D.4
  • 27
    • 79952211418 scopus 로고    scopus 로고
    • Molecular determinants of transient and reversible induced up-regulation of CaCDR1 in azole susceptible clinical isolates of Candida albicans
    • [in press]
    • Manoharlal R, Sharma M, Prasad R. Molecular determinants of transient and reversible induced up-regulation of CaCDR1 in azole susceptible clinical isolates of Candida albicans . Biosci Rep 2010 [in press]
    • Biosci Rep , vol.2010
    • Manoharlal, R.1    Sharma, M.2    Prasad, R.3
  • 28
    • 41649118757 scopus 로고    scopus 로고
    • A nuclear receptor-like pathway regulating multidrug resistance in fungi
    • Thakur JK, Arthanari H, Yang F, et al. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008; 452 : 604-609.
    • (2008) Nature , vol.452 , pp. 604-609
    • Thakur, J.K.1    Arthanari, H.2    Yang, F.3
  • 29
    • 54449085246 scopus 로고    scopus 로고
    • Weak organic acids trigger conformational changes of the yeast transcription factor War1 in vivo to elicit stress adaptation
    • Gregori C, Schuller C, Frohner IE, Ammerer G, Kuchler K. Weak organic acids trigger conformational changes of the yeast transcription factor War1 in vivo to elicit stress adaptation. J Biol Chem 2008; 25752-25764
    • (2008) J Biol Chem , pp. 25752-25764
    • Gregori, C.1    Schuller, C.2    Frohner, I.E.3    Ammerer, G.4    Kuchler, K.5
  • 30
    • 2442431686 scopus 로고    scopus 로고
    • Adriamycin alters the expression of drug effl ux pumps and confers amphotericin B tolerance in Candida albicans
    • O Keeffe J, Kavanagh K. Adriamycin alters the expression of drug effl ux pumps and confers amphotericin B tolerance in Candida albicans . Anticancer Res 2004; 24 : 405-408.
    • (2004) Anticancer Res , vol.24 , pp. 405-408
    • Keeffe, J.O.1    Kavanagh, K.2
  • 31
    • 0032856116 scopus 로고    scopus 로고
    • Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents
    • Henry KW, Cruz MC, Katiyar SK, Edlind TD. Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents. Antimicrob Agents Chemother 1999; 43 : 1968-1974.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1968-1974
    • Henry, K.W.1    Cruz, M.C.2    Katiyar, S.K.3    Edlind, T.D.4
  • 32
    • 0031038192 scopus 로고    scopus 로고
    • Reversible fl uconazole resistance in Candida albicans: A potential in vitro model
    • Calvet HM, Yeaman MR, Filler SG. Reversible fl uconazole resistance in Candida albicans : a potential in vitro model. Antimicrob Agents Chemother 1997; 41 : 535-539.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 535-539
    • Calvet, H.M.1    Yeaman, M.R.2    Filler, S.G.3
  • 33
    • 0034051543 scopus 로고    scopus 로고
    • Evolution of drug resistance in experimental populations of Candida albicans
    • Cowen LE, Sanglard D, Calabrese D, et al. Evolution of drug resistance in experimental populations of Candida albicans . J Bacteriol 2000; 182 : 1515-1522.
    • (2000) J Bacteriol , vol.182 , pp. 1515-1522
    • Cowen, L.E.1    Sanglard, D.2    Calabrese, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.