메뉴 건너뛰기




Volumn 20, Issue 11, 2012, Pages 1316-1325

Tissue engineering approaches to degenerative disc disease - A meta-analysis of controlled animal trials

Author keywords

Disc degeneration; Disc disease; Evidence based medicine; Regenerative medicine; Tissue engineering

Indexed keywords

ATELOCOLLAGEN; BIOMATERIAL; FIBRIN; GELATIN; MICROSPHERE; POLYGLYCOLIC ACID; PROSTAGLANDIN A; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84866455048     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.06.001     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 34147105611 scopus 로고    scopus 로고
    • Epidemiology and risk factors for spine pain
    • Rubin D.I. Epidemiology and risk factors for spine pain. Neurol Clin 2007, 25(2):353-371.
    • (2007) Neurol Clin , vol.25 , Issue.2 , pp. 353-371
    • Rubin, D.I.1
  • 2
    • 23244436360 scopus 로고    scopus 로고
    • The transition from acute to subacute and chronic low back pain: a study based on determinants of quality of life and prediction of chronic disability
    • Kovacs F.M., Abraira V., Zamora J., Fernandez C. The transition from acute to subacute and chronic low back pain: a study based on determinants of quality of life and prediction of chronic disability. Spine (Phila Pa 1976) 2005, 30(15):1786-1792.
    • (2005) Spine (Phila Pa 1976) , vol.30 , Issue.15 , pp. 1786-1792
    • Kovacs, F.M.1    Abraira, V.2    Zamora, J.3    Fernandez, C.4
  • 3
    • 33645556769 scopus 로고    scopus 로고
    • Lumbar disc disorders and low-back pain: socioeconomic factors and consequences
    • Katz J.N. Lumbar disc disorders and low-back pain: socioeconomic factors and consequences. J Bone Jt Surg Am 2006, 88(Suppl 2):21-24.
    • (2006) J Bone Jt Surg Am , vol.88 , Issue.SUPPL. 2 , pp. 21-24
    • Katz, J.N.1
  • 4
    • 0029813162 scopus 로고    scopus 로고
    • The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration
    • Antoniou J., Steffen T., Nelson F., Winterbottom N., Hollander A.P., Poole R.A., et al. The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Clin Invest 1996, 98(4):996-1003.
    • (1996) J Clin Invest , vol.98 , Issue.4 , pp. 996-1003
    • Antoniou, J.1    Steffen, T.2    Nelson, F.3    Winterbottom, N.4    Hollander, A.P.5    Poole, R.A.6
  • 5
    • 0029008944 scopus 로고
    • Aging and degeneration of the human intervertebral disc
    • Buckwalter J.A. Aging and degeneration of the human intervertebral disc. Spine (Phila Pa 1976) 1995, 20(11):1307-1314.
    • (1995) Spine (Phila Pa 1976) , vol.20 , Issue.11 , pp. 1307-1314
    • Buckwalter, J.A.1
  • 6
    • 0029894675 scopus 로고    scopus 로고
    • The human lumbar endplate. Evidence of changes in biosynthesis and denaturation of the extracellular matrix with growth, maturation, aging, and degeneration
    • Antoniou J., Goudsouzian N.M., Heathfield T.F., Winterbottom N., Steffen T., Poole A.R., et al. The human lumbar endplate. Evidence of changes in biosynthesis and denaturation of the extracellular matrix with growth, maturation, aging, and degeneration. Spine (Phila Pa 1976) 1996, 21(10):1153-1161.
    • (1996) Spine (Phila Pa 1976) , vol.21 , Issue.10 , pp. 1153-1161
    • Antoniou, J.1    Goudsouzian, N.M.2    Heathfield, T.F.3    Winterbottom, N.4    Steffen, T.5    Poole, A.R.6
  • 7
    • 12344260899 scopus 로고    scopus 로고
    • Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc
    • Mwale F., Roughley P., Antoniou J. Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc. Eur Cell Mater 2004, 8:58-63.
    • (2004) Eur Cell Mater , vol.8 , pp. 58-63
    • Mwale, F.1    Roughley, P.2    Antoniou, J.3
  • 8
    • 14844362721 scopus 로고    scopus 로고
    • ISSLS prize winner: a study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs
    • Rajasekaran S., Babu J.N., Arun R., Armstrong B.R., Shetty A.P., Murugan S. ISSLS prize winner: a study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs. Spine (Phila Pa 1976) 2004, 29(23):2654-2667.
    • (2004) Spine (Phila Pa 1976) , vol.29 , Issue.23 , pp. 2654-2667
    • Rajasekaran, S.1    Babu, J.N.2    Arun, R.3    Armstrong, B.R.4    Shetty, A.P.5    Murugan, S.6
  • 12
    • 11144304192 scopus 로고    scopus 로고
    • The effect of spinal steroid injections for degenerative disc disease
    • Buttermann G.R. The effect of spinal steroid injections for degenerative disc disease. Spine J 2004, 4(5):495-505.
    • (2004) Spine J , vol.4 , Issue.5 , pp. 495-505
    • Buttermann, G.R.1
  • 13
    • 75049084957 scopus 로고    scopus 로고
    • Frequency and clinical meaning of long-term degenerative changes after lumbar discectomy visualized on imaging tests
    • Mariconda M., Galasso O., Attingenti P., Federico G., Milano C. Frequency and clinical meaning of long-term degenerative changes after lumbar discectomy visualized on imaging tests. Eur Spine J 2010, 19(1):136-143.
    • (2010) Eur Spine J , vol.19 , Issue.1 , pp. 136-143
    • Mariconda, M.1    Galasso, O.2    Attingenti, P.3    Federico, G.4    Milano, C.5
  • 14
    • 0034885266 scopus 로고    scopus 로고
    • Long-term follow-up of functional outcomes and radiographic changes at adjacent levels following lumbar spine fusion for degenerative disc disease
    • Kumar M.N., Jacquot F., Hall H. Long-term follow-up of functional outcomes and radiographic changes at adjacent levels following lumbar spine fusion for degenerative disc disease. Eur Spine J 2001, 10(4):309-313.
    • (2001) Eur Spine J , vol.10 , Issue.4 , pp. 309-313
    • Kumar, M.N.1    Jacquot, F.2    Hall, H.3
  • 15
    • 77956215413 scopus 로고    scopus 로고
    • A systematic review of randomized trials on the effect of cervical disc arthroplasty on reducing adjacent-level degeneration
    • Botelho R.V., Moraes O.J., Fernandes G.A., Buscariolli Y.S., Bernardo W.M. A systematic review of randomized trials on the effect of cervical disc arthroplasty on reducing adjacent-level degeneration. Neurosurg Focus 2010, 28(6):E5.
    • (2010) Neurosurg Focus , vol.28 , Issue.6
    • Botelho, R.V.1    Moraes, O.J.2    Fernandes, G.A.3    Buscariolli, Y.S.4    Bernardo, W.M.5
  • 16
    • 13444278496 scopus 로고    scopus 로고
    • Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits
    • An H.S., Takegami K., Kamada H., Nguyen C.M., Thonar E.J., Singh K., et al. Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits. Spine (Phila Pa 1976) 2005, 30(1):25-31.
    • (2005) Spine (Phila Pa 1976) , vol.30 , Issue.1 , pp. 25-31
    • An, H.S.1    Takegami, K.2    Kamada, H.3    Nguyen, C.M.4    Thonar, E.J.5    Singh, K.6
  • 17
    • 34248347420 scopus 로고    scopus 로고
    • Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC
    • Imai Y., Okuma M., An H.S., Nakagawa K., Yamada M., Muehleman C., et al. Restoration of disc height loss by recombinant human osteogenic protein-1 injection into intervertebral discs undergoing degeneration induced by an intradiscal injection of chondroitinase ABC. Spine (Phila Pa 1976) 2007, 32(11):1197-1205.
    • (2007) Spine (Phila Pa 1976) , vol.32 , Issue.11 , pp. 1197-1205
    • Imai, Y.1    Okuma, M.2    An, H.S.3    Nakagawa, K.4    Yamada, M.5    Muehleman, C.6
  • 18
    • 33645765778 scopus 로고    scopus 로고
    • Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model
    • Masuda K., Imai Y., Okuma M., Muehleman C., Nakagawa K., Akeda K., et al. Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model. Spine (Phila Pa 1976) 2006, 31(7):742-754.
    • (2006) Spine (Phila Pa 1976) , vol.31 , Issue.7 , pp. 742-754
    • Masuda, K.1    Imai, Y.2    Okuma, M.3    Muehleman, C.4    Nakagawa, K.5    Akeda, K.6
  • 19
    • 0032527361 scopus 로고    scopus 로고
    • Percutaneous reinsertion of the nucleus pulposus. An experimental study
    • Nishimura K., Mochida J. Percutaneous reinsertion of the nucleus pulposus. An experimental study. Spine (Phila Pa 1976) 1998, 23(14):1531-1538.
    • (1998) Spine (Phila Pa 1976) , vol.23 , Issue.14 , pp. 1531-1538
    • Nishimura, K.1    Mochida, J.2
  • 20
    • 0034319143 scopus 로고    scopus 로고
    • Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study
    • Okuma M., Mochida J., Nishimura K., Sakabe K., Seiki K. Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study. J Orthop Res 2000, 18(6):988-997.
    • (2000) J Orthop Res , vol.18 , Issue.6 , pp. 988-997
    • Okuma, M.1    Mochida, J.2    Nishimura, K.3    Sakabe, K.4    Seiki, K.5
  • 21
    • 26844531456 scopus 로고    scopus 로고
    • Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc
    • Sakai D., Mochida J., Iwashina T., Hiyama A., Omi H., Imai M., et al. Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc. Biomaterials 2006, 27(3):335-345.
    • (2006) Biomaterials , vol.27 , Issue.3 , pp. 335-345
    • Sakai, D.1    Mochida, J.2    Iwashina, T.3    Hiyama, A.4    Omi, H.5    Imai, M.6
  • 22
    • 27644541907 scopus 로고    scopus 로고
    • Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration
    • Sakai D., Mochida J., Iwashina T., Watanabe T., Nakai T., Ando K., et al. Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration. Spine (Phila Pa 1976) 2005, 30(21):2379-2387.
    • (2005) Spine (Phila Pa 1976) , vol.30 , Issue.21 , pp. 2379-2387
    • Sakai, D.1    Mochida, J.2    Iwashina, T.3    Watanabe, T.4    Nakai, T.5    Ando, K.6
  • 23
    • 0037708391 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration
    • Sakai D., Mochida J., Yamamoto Y., Nomura T., Okuma M., Nishimura K., et al. Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. Biomaterials 2003, 24(20):3531-3541.
    • (2003) Biomaterials , vol.24 , Issue.20 , pp. 3531-3541
    • Sakai, D.1    Mochida, J.2    Yamamoto, Y.3    Nomura, T.4    Okuma, M.5    Nishimura, K.6
  • 24
    • 0001779594 scopus 로고    scopus 로고
    • Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation
    • Gruber H.E., Hanley E.N. Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation. BMC Musculoskelet Disord 2000, 1:1.
    • (2000) BMC Musculoskelet Disord , vol.1 , pp. 1
    • Gruber, H.E.1    Hanley, E.N.2
  • 25
    • 0037841844 scopus 로고    scopus 로고
    • Tissue engineering of the intervertebral disc with cultured annulus fibrosus cells using atelocollagen honeycomb-shaped scaffold with a membrane seal (ACHMS scaffold)
    • Sato M., Kikuchi M., Ishihara M., Ishihara M., Asazuma T., Kikuchi T., et al. Tissue engineering of the intervertebral disc with cultured annulus fibrosus cells using atelocollagen honeycomb-shaped scaffold with a membrane seal (ACHMS scaffold). Med Biol Eng Comput 2003, 41(3):365-371.
    • (2003) Med Biol Eng Comput , vol.41 , Issue.3 , pp. 365-371
    • Sato, M.1    Kikuchi, M.2    Ishihara, M.3    Ishihara, M.4    Asazuma, T.5    Kikuchi, T.6
  • 28
    • 79952365932 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells and nucleus pulposus cells in a degenerative disc model in rabbits: a comparison of 2 cell types as potential candidates for disc regeneration
    • Feng G., Zhao X., Liu H., Zhang H., Chen X., Shi R., et al. Transplantation of mesenchymal stem cells and nucleus pulposus cells in a degenerative disc model in rabbits: a comparison of 2 cell types as potential candidates for disc regeneration. J Neurosurg Spine 2011, 14(3):322-329.
    • (2011) J Neurosurg Spine , vol.14 , Issue.3 , pp. 322-329
    • Feng, G.1    Zhao, X.2    Liu, H.3    Zhang, H.4    Chen, X.5    Shi, R.6
  • 29
    • 0035449038 scopus 로고    scopus 로고
    • Magnetic resonance classification of lumbar intervertebral disc degeneration
    • Pfirrmann C.W., Metzdorf A., Zanetti M., Hodler J., Boos N. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976) 2001, 26(17):1873-1878.
    • (2001) Spine (Phila Pa 1976) , vol.26 , Issue.17 , pp. 1873-1878
    • Pfirrmann, C.W.1    Metzdorf, A.2    Zanetti, M.3    Hodler, J.4    Boos, N.5
  • 30
    • 43649093152 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells in a canine disc degeneration model
    • Hiyama A., Mochida J., Iwashina T., Omi H., Watanabe T., Serigano K., et al. Transplantation of mesenchymal stem cells in a canine disc degeneration model. J Orthop Res 2008, 26(5):589-600.
    • (2008) J Orthop Res , vol.26 , Issue.5 , pp. 589-600
    • Hiyama, A.1    Mochida, J.2    Iwashina, T.3    Omi, H.4    Watanabe, T.5    Serigano, K.6
  • 31
    • 78149416500 scopus 로고    scopus 로고
    • Regeneration of intervertebral discs in a rat disc degeneration model by implanted adipose-tissue-derived stromal cells
    • Jeong J.H., Lee J.H., Jin E.S., Min J.K., Jeon S.R., Choi K.H. Regeneration of intervertebral discs in a rat disc degeneration model by implanted adipose-tissue-derived stromal cells. Acta Neurochir (Wien) 2010, 152(10):1771-1777.
    • (2010) Acta Neurochir (Wien) , vol.152 , Issue.10 , pp. 1771-1777
    • Jeong, J.H.1    Lee, J.H.2    Jin, E.S.3    Min, J.K.4    Jeon, S.R.5    Choi, K.H.6
  • 32
    • 2942536282 scopus 로고    scopus 로고
    • Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs
    • Crevensten G., Walsh A.J., Ananthakrishnan D., Page P., Wahba G.M., Lotz J.C., et al. Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs. Ann Biomed Eng 2004, 32(3):430-434.
    • (2004) Ann Biomed Eng , vol.32 , Issue.3 , pp. 430-434
    • Crevensten, G.1    Walsh, A.J.2    Ananthakrishnan, D.3    Page, P.4    Wahba, G.M.5    Lotz, J.C.6
  • 33
    • 78049386105 scopus 로고    scopus 로고
    • Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits
    • Miyamoto T., Muneta T., Tabuchi T., Matsumoto K., Saito H., Tsuji K., et al. Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits. Arthritis Res Ther 2010, 12(6):R206.
    • (2010) Arthritis Res Ther , vol.12 , Issue.6
    • Miyamoto, T.1    Muneta, T.2    Tabuchi, T.3    Matsumoto, K.4    Saito, H.5    Tsuji, K.6
  • 34
    • 77957203095 scopus 로고    scopus 로고
    • Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model
    • Serigano K., Sakai D., Hiyama A., Tamura F., Tanaka M., Mochida J. Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model. J Orthop Res 2010, 28(10):1267-1275.
    • (2010) J Orthop Res , vol.28 , Issue.10 , pp. 1267-1275
    • Serigano, K.1    Sakai, D.2    Hiyama, A.3    Tamura, F.4    Tanaka, M.5    Mochida, J.6
  • 35
    • 77956183003 scopus 로고    scopus 로고
    • Transplanted mesenchymal stem cells with pure fibrinous gelatin-transforming growth factor-beta1 decrease rabbit intervertebral disc degeneration
    • Yang H., Wu J., Liu J., Ebraheim M., Castillo S., Liu X., et al. Transplanted mesenchymal stem cells with pure fibrinous gelatin-transforming growth factor-beta1 decrease rabbit intervertebral disc degeneration. Spine J 2010, 10(9):802-810.
    • (2010) Spine J , vol.10 , Issue.9 , pp. 802-810
    • Yang, H.1    Wu, J.2    Liu, J.3    Ebraheim, M.4    Castillo, S.5    Liu, X.6
  • 36
    • 67349178136 scopus 로고    scopus 로고
    • Human mesenchymal stem cells implantation into the degenerated coccygeal disc of the rat
    • Jeong J.H., Jin E.S., Min J.K., Jeon S.R., Park C.S., Kim H.S., et al. Human mesenchymal stem cells implantation into the degenerated coccygeal disc of the rat. Cytotechnology 2009, 59(1):55-64.
    • (2009) Cytotechnology , vol.59 , Issue.1 , pp. 55-64
    • Jeong, J.H.1    Jin, E.S.2    Min, J.K.3    Jeon, S.R.4    Park, C.S.5    Kim, H.S.6
  • 37
    • 33646779546 scopus 로고    scopus 로고
    • Feasibility of using a human nucleus pulposus cell line as a cell source in cell transplantation therapy for intervertebral disc degeneration
    • Iwashina T., Mochida J., Sakai D., Yamamoto Y., Miyazaki T., Ando K., et al. Feasibility of using a human nucleus pulposus cell line as a cell source in cell transplantation therapy for intervertebral disc degeneration. Spine (Phila Pa 1976) 2006, 31(11):1177-1186.
    • (2006) Spine (Phila Pa 1976) , vol.31 , Issue.11 , pp. 1177-1186
    • Iwashina, T.1    Mochida, J.2    Sakai, D.3    Yamamoto, Y.4    Miyazaki, T.5    Ando, K.6
  • 38
    • 77954528317 scopus 로고    scopus 로고
    • Experimental intervertebral disc regeneration with tissue-engineered composite in a canine model
    • Ruan D.K., Xin H., Zhang C., Wang C., Xu C., Li C., et al. Experimental intervertebral disc regeneration with tissue-engineered composite in a canine model. Tissue Eng Part A 2010, 16(7):2381-2389.
    • (2010) Tissue Eng Part A , vol.16 , Issue.7 , pp. 2381-2389
    • Ruan, D.K.1    Xin, H.2    Zhang, C.3    Wang, C.4    Xu, C.5    Li, C.6
  • 39
    • 50649096453 scopus 로고    scopus 로고
    • Regeneration of intervertebral disc tissue by resorbable cell-free polyglycolic acid-based implants in a rabbit model of disc degeneration
    • Abbushi A., Endres M., Cabraja M., Kroppenstedt S.N., Thomale U.W., Sittinger M., et al. Regeneration of intervertebral disc tissue by resorbable cell-free polyglycolic acid-based implants in a rabbit model of disc degeneration. Spine (Phila Pa 1976) 2008, 33(14):1527-1532.
    • (2008) Spine (Phila Pa 1976) , vol.33 , Issue.14 , pp. 1527-1532
    • Abbushi, A.1    Endres, M.2    Cabraja, M.3    Kroppenstedt, S.N.4    Thomale, U.W.5    Sittinger, M.6
  • 40
    • 72049121634 scopus 로고    scopus 로고
    • Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs
    • Sawamura K., Ikeda T., Nagae M., Okamoto S., Mikami Y., Hase H., et al. Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs. Tissue Eng Part A 2009, 15(12):3719-3727.
    • (2009) Tissue Eng Part A , vol.15 , Issue.12 , pp. 3719-3727
    • Sawamura, K.1    Ikeda, T.2    Nagae, M.3    Okamoto, S.4    Mikami, Y.5    Hase, H.6
  • 41
    • 0035147583 scopus 로고    scopus 로고
    • Meta-analyses in orthopaedic surgery. A systematic review of their methodologies
    • Bhandari M., Morrow F., Kulkarni A.V., Tornetta P. Meta-analyses in orthopaedic surgery. A systematic review of their methodologies. J Bone Jt Surg 2001, 83-A:15-24.
    • (2001) J Bone Jt Surg , pp. 15-24
    • Bhandari, M.1    Morrow, F.2    Kulkarni, A.V.3    Tornetta, P.4
  • 42
    • 38649097225 scopus 로고    scopus 로고
    • Are animal models useful for studying human disc disorders/degeneration?
    • Alini M., Eisenstein S.M., Ito K., Little C., Kettler A.A., Masuda K., et al. Are animal models useful for studying human disc disorders/degeneration?. Eur Spine J 2008, 17(1):2-19.
    • (2008) Eur Spine J , vol.17 , Issue.1 , pp. 2-19
    • Alini, M.1    Eisenstein, S.M.2    Ito, K.3    Little, C.4    Kettler, A.A.5    Masuda, K.6
  • 43
    • 33845633749 scopus 로고    scopus 로고
    • Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes
    • Erwin W.M., Ashman K., O'Donnel P., Inman R.D. Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes. Arthritis Rheum 2006, 54(12):3859-3867.
    • (2006) Arthritis Rheum , vol.54 , Issue.12 , pp. 3859-3867
    • Erwin, W.M.1    Ashman, K.2    O'Donnel, P.3    Inman, R.D.4
  • 44
    • 33646557978 scopus 로고    scopus 로고
    • Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation
    • Erwin W.M., Inman R.D. Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation. Spine (Phila Pa 1976) 2006, 31(10):1094-1099.
    • (2006) Spine (Phila Pa 1976) , vol.31 , Issue.10 , pp. 1094-1099
    • Erwin, W.M.1    Inman, R.D.2
  • 45
    • 79957658251 scopus 로고    scopus 로고
    • Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells
    • Purmessur D., Schek R.M., Abbott R.D., Ballif B.A., Godburn K.E., Iatridis J.C. Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells. Arthritis Res Ther 2011, 13(3):R81.
    • (2011) Arthritis Res Ther , vol.13 , Issue.3
    • Purmessur, D.1    Schek, R.M.2    Abbott, R.D.3    Ballif, B.A.4    Godburn, K.E.5    Iatridis, J.C.6
  • 46
    • 67651151247 scopus 로고    scopus 로고
    • Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus
    • Sakai D., Nakai T., Mochida J., Alini M., Grad S. Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus. Spine (Phila Pa 1976) 2009, 34(14):1448-1456.
    • (2009) Spine (Phila Pa 1976) , vol.34 , Issue.14 , pp. 1448-1456
    • Sakai, D.1    Nakai, T.2    Mochida, J.3    Alini, M.4    Grad, S.5
  • 47
    • 77954980434 scopus 로고    scopus 로고
    • Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord
    • Risbud M.V., Schaer T.P., Shapiro I.M. Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord. Dev Dyn 2010, 239(8):2141-2148.
    • (2010) Dev Dyn , vol.239 , Issue.8 , pp. 2141-2148
    • Risbud, M.V.1    Schaer, T.P.2    Shapiro, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.