Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells

Arthritis Research and Therapy

Volumn 13, Issue 3, 2011, Pages

  Purmessur, Devina ^a   Schek, Rachel M ^b   Abbott, Rosalyn D ^b   Ballif, Bryan A ^b   Godburn, Karolyn E ^b   Iatridis, James C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; CLUSTERIN; COLLAGEN TYPE 1; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGEN TYPE 3; GLYCOSAMINOGLYCAN; PROTEOGLYCAN; TENASCIN; TRANSCRIPTION FACTOR SOX9; CYTOKINE; SCLEROPROTEIN; SIGNAL PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CATABOLISM; CELL DIFFERENTIATION; CELL HYPOXIA; CELL VIABILITY; CHONDROGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; EMBRYO CELL; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INTERVERTEBRAL DISK; MESENCHYMAL STEM CELL; NONHUMAN; NOTOCHORD; NOTOCHORDAL CELL; NUCLEUS PULPOSUS; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEOMICS; UPREGULATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; METHODOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; SWINE; TUMOR MICROENVIRONMENT;

ADULT; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; CELLULAR MICROENVIRONMENT; CULTURE MEDIA, CONDITIONED; CYTOKINES; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; GLYCOSAMINOGLYCANS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERVERTEBRAL DISC; MESENCHYMAL STEM CELLS; NOTOCHORD; PHENOTYPE; PROTEOGLYCANS; PROTEOMICS; SWINE; YOUNG ADULT;

EID: 79957658251     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3344     Document Type: Article

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