The extracellular and transmembrane domains of the γC and interleukin (IL)-13 receptor α1 chains, not their cytoplasmic domains, dictate the nature of signaling responses to IL-4 and IL-13

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 31948-31961

  Heller, Nicola M ^a   Qi, Xiulan ^a   Gesbert, Franck ^b   Keegan, Achsah D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED MACROPHAGES; ADAPTER PROTEINS; ALLERGIC DISEASE; CHIMERIC RECEPTORS; CHO CELL; CONTROL SIGNALING; CYTOPLASMIC DOMAINS; DRUG DESIGN; EXTRACELLULAR; INSULIN RECEPTORS; TRANS-MEMBRANE DOMAINS; TRUNCATION MUTANTS; TYROSINE PHOSPHORYLATION; TYROSINE RESIDUES; WILD TYPES;

ACTIVATION ANALYSIS; AMINO ACIDS; BIOLOGICAL MEMBRANES; CYTOLOGY; GENE EXPRESSION; PHOSPHORYLATION; SIGNALING;

CLONE CELLS;

ADAPTER PROTEIN; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 13 RECEPTOR GAMMA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR; IRS 1 PROTEIN; IRS 2 PROTEIN; JANUS KINASE 3; MUTANT PROTEIN; PROTEIN; STAT5 PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; CYTOPLASMIC DOMAIN; DRUG DESIGN; ENZYME ACTIVATION; EXTRACELLULAR AND TRANSMEMBRANE DOMAIN; L CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; CYTOKINES; CYTOPLASM; FLOW CYTOMETRY; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-4; MICE; MODELS, BIOLOGICAL; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IGE; RECEPTORS, INTERLEUKIN-4; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR;

EID: 84866390174     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.348896     Document Type: Article

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