Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor

Molecular Immunology

Volumn 47, Issue 6, 2010, Pages 1207-1215

  Zhong, Jun ^a   Liu, Xuedong ^b   Pandey, Akhilesh ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Chimeric receptor; Proliferation; TSLP

Indexed keywords

CYTOKINE RECEPTOR; ERYTHROPOIETIN RECEPTOR; JANUS KINASE 2; MEMBRANE PROTEIN; THYMIC STROMAL LYMPHOPOIETIN RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; CHIMERA; CONTROLLED STUDY; CYTOPLASM; DIMERIZATION; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CYTOPLASM; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOKINE; RECEPTORS, ERYTHROPOIETIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77149167279     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.12.017     Document Type: Article

References (20)

1. 8+ T cells. Clin Exp Immunol 154 (2008) 98-106
2. Brown V.I., Hulitt J., Fish J., Sheen C., Bruno M., Xu Q., Carroll M., Fang J., Teachey D., and Grupp S.A. Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling. Cancer Res 67 (2007) 9963-9970
3. Carpino N., Thierfelder W.E., Chang M.S., Saris C., Turner S.J., Ziegler S.F., and Ihle J.N. Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development. Mol Cell Biol 24 (2004) 2584-2592
4. Constantinescu S.N., Huang L.J., Nam H., and Lodish H.F. The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif. Mol Cell 7 (2001) 377-385
5. Ferrag F., Pezet A., Chiarenza A., Buteau H., Nelson B.H., Goffin V., and Kelly P.A. Homodimerization of IL-2 receptor beta chain is necessary and sufficient to activate Jak2 and downstream signaling pathways. FEBS Lett 421 (1998) 32-36
6. Friend S.L., Hosier S., Nelson A., Foxworthe D., Williams D.E., and Farr A. A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells. Exp Hematol 22 (1994) 321-328
7. Fujio K., Nosaka T., Kojima T., Kawashima T., Yahata T., Copeland N.G., Gilbert D.J., Jenkins N.A., Yamamoto K., Nishimura T., and Kitamura T. Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain. Blood 95 (2000) 2204-2210
8. Hiroyama T., Iwama A., Morita Y., Nakamura Y., Shibuya A., and Nakauchi H. Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells. Biochem Biophys Res Commun 272 (2000) 224-229
9. Koyama K., Ozawa T., Hatsushika K., Ando T., Takano S., Wako M., Suenaga F., Ohnuma Y., Ohba T., Katoh R., Sugiyama H., Hamada Y., Ogawa H., Okumura K., and Nakao A. A possible role for TSLP in inflammatory arthritis. Biochem Biophys Res Commun 357 (2007) 99-104
10. Levin S.D., Koelling R.M., Friend S.L., Isaksen D.E., Ziegler S.F., Perlmutter R.M., and Farr A.G. Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. J Immunol 162 (1999) 677-683
11. Liu X., Constantinescu S.N., Sun Y., Bogan J.S., Hirsch D., Weinberg R.A., and Lodish H.F. Generation of mammalian cells stably expressing multiple genes at predetermined levels. Anal Biochem 280 (2000) 20-28
12. Pandey A., Ozaki K., Baumann H., Levin S.D., Puel A., Farr A.G., Ziegler S.F., Leonard W.J., and Lodish H.F. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol 1 (2000) 59-64
13. Park L.S., Martin U., Garka K., Gliniak B., Di Santo J.P., Muller W., Largaespada D.A., Copeland N.G., Jenkins N.A., Farr A.G., Ziegler S.F., Morrissey P.J., Paxton R., and Sims J.E. Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: formation of a functional heteromeric complex requires interleukin 7 receptor. J Exp Med 192 (2000) 659-670
14. Pelletier S., Gingras S., Funakoshi-Tago M., Howell S., and Ihle J.N. Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function. Mol Cell Biol 26 (2006) 8527-8538
15. Reche P.A., Soumelis V., Gorman D.M., Clifford T., Liu M., Travis M., Zurawski S.M., Johnston J., Liu Y.J., Spits H., de Waal Malefyt R., Kastelein R.A., and Bazan J.F. Human thymic stromal lymphopoietin preferentially stimulates myeloid cells. J Immunol 167 (2001) 336-343
16. 4+ T cells. J Immunol 178 (2007) 6720-6724
17. Ying S., O'Connor B., Ratoff J., Meng Q., Mallett K., Cousins D., Robinson D., Zhang G., Zhao J., Lee T.H., and Corrigan C. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol 174 (2005) 8183-8190
18. Zang H., Sato K., Nakajima H., McKay C., Ney P.A., and Ihle J.N. The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis. EMBO J 20 (2001) 3156-3166
19. Zhang W., Wang J., Wang Q., Chen G., Zhang J., Chen T., Wan T., Zhang Y., and Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun 281 (2001) 878-883
20. Ziegler S.F., and Liu Y.J. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol 7 (2006) 709-714