메뉴 건너뛰기




Volumn 18, Issue 28, 2012, Pages 4385-4413

Effects of ACE-inhibitors and angiotensin receptor blockers on inflammation

Author keywords

ACE inhibitors; Angiotensin recpetor blockers; Inflammation; Renin angiotensin aldosteron system (RAAS)

Indexed keywords

ALDOSTERONE; AMLODIPINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; C REACTIVE PROTEIN; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; EPROSARTAN; FIBRINOGEN; FOSINOPRIL; IRBESARTAN; LISINOPRIL; LOSARTAN; MINERALOCORTICOID RECEPTOR; NIFEDIPINE; OLMESARTAN; OMAPATRILAT; PERINDOPRIL; QUINAPRIL; RAMIPRIL; SPIRONOLACTONE; TELMISARTAN; TRANDOLAPRIL; UNINDEXED DRUG; VALSARTAN; ZOFENOPRIL;

EID: 84866382268     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212802481282     Document Type: Article
Times cited : (101)

References (263)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340(2): 115-126.
    • (1999) N Engl J Med , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 2
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342: 836-843.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 3
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rew 2006; 86: 515-581
    • (2006) Physiol Rew , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 6
    • 15444373092 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms in vascular injury in hypertension: Role of angiotensin II
    • Touyz RM. Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II. Curr Opin Nephrol Hypertens 2005; 14: 125-131
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 125-131
    • Touyz, R.M.1
  • 7
    • 1442348127 scopus 로고    scopus 로고
    • Pathogenesis of structural vascular changes in hypertension
    • Simon G. Pathogenesis of structural vascular changes in hypertension. J Hypertens 2004; 22: 3-10.
    • (2004) J Hypertens , vol.22 , pp. 3-10
    • Simon, G.1
  • 8
    • 34250350040 scopus 로고    scopus 로고
    • Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia G, de Backer G, Dominiczak A, et al. Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007; 25(6): 1105-1187.
    • (2007) J Hypertens , vol.25 , Issue.6 , pp. 1105-1187
    • Mancia, G.1    de Backer, G.2    Dominiczak, A.3
  • 11
    • 0030667865 scopus 로고    scopus 로고
    • Hypothesis: The role of acquired tubulointerstitial disease in the pathogenesis of salt-dependent hypertension
    • Johnson RJ, Schreiner GF. Hypothesis: the role of acquired tubulointerstitial disease in the pathogenesis of salt-dependent hypertension. Kidney Int 1997; 52: 1169-1179.
    • (1997) Kidney Int , vol.52 , pp. 1169-1179
    • Johnson, R.J.1    Schreiner, G.F.2
  • 12
    • 0037340168 scopus 로고    scopus 로고
    • The kidney, hypertension, and obesity
    • Hall JE. The kidney, hypertension, and obesity. Hypertension 2003; 41: 625-633.
    • (2003) Hypertension , vol.41 , pp. 625-633
    • Hall, J.E.1
  • 13
    • 34948825774 scopus 로고    scopus 로고
    • Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction
    • Guzik TJ, Hoch NE, Brown KA, et al. Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med 2007; 204: 2449-2460.
    • (2007) J Exp Med , vol.204 , pp. 2449-2460
    • Guzik, T.J.1    Hoch, N.E.2    Brown, K.A.3
  • 15
    • 2542509493 scopus 로고    scopus 로고
    • Preactivation peripheral blood monocytes in patients with essential hypertension
    • Dorffel Y, Latsh C, Stuhlmuller B, et al. Preactivation peripheral blood monocytes in patients with essential hypertension. Hypertension 1999; 34: 113-117.
    • (1999) Hypertension , vol.34 , pp. 113-117
    • Dorffel, Y.1    Latsh, C.2    Stuhlmuller, B.3
  • 16
    • 0028604311 scopus 로고
    • Monocyte adhesion to cerebromicrovascular endothelial cells derived from hypertensive and normotensive rats
    • McCarron RM, Wang L, Siren AL, Spatz M, Hallenbeck JM. Monocyte adhesion to cerebromicrovascular endothelial cells derived from hypertensive and normotensive rats. Am J Physiol 1994; 267: H2491-H2497.
    • (1994) Am J Physiol , vol.267
    • McCarron, R.M.1    Wang, L.2    Siren, A.L.3    Spatz, M.4    Hallenbeck, J.M.5
  • 17
    • 0142042339 scopus 로고    scopus 로고
    • Increased C-reactive protein concentrations in never- treated hypertension: The role of systolic and pulse pressures
    • Schillaci G, Pirro M, Gemelli F, et al. Increased C-reactive protein concentrations in never- treated hypertension: the role of systolic and pulse pressures. J Hypertens. 2003; 21: 1841-1846.
    • (2003) J Hypertens , vol.21 , pp. 1841-1846
    • Schillaci, G.1    Pirro, M.2    Gemelli, F.3
  • 19
    • 0030806863 scopus 로고    scopus 로고
    • Superoxide anion radical, superoxide dismutases, and related matters
    • Fridovich I. Superoxide anion radical, superoxide dismutases, and related matters. J Biol Chem. 1997; 272: 18515-18517.
    • (1997) J Biol Chem , vol.272 , pp. 18515-18517
    • Fridovich, I.1
  • 20
    • 79958792296 scopus 로고    scopus 로고
    • Exercise-induced oxidative stress in humans: Cause and consequences
    • 2010 Dec 16. [Epub ahead of print]
    • Powers SK, Nelson WB, Hudson MB. Exercise-induced oxidative stress in humans: Cause and consequences. Free Radic Biol Med. 2010 Dec 16. [Epub ahead of print].
    • Free Radic Biol Med
    • Powers, S.K.1    Nelson, W.B.2    Hudson, M.B.3
  • 21
    • 0022428152 scopus 로고
    • Oxidative stress: Damage to intact cells and organs
    • Sies H, Cadenas E. Oxidative stress: damage to intact cells and organs. Philos Trans R Soc Lond B Biol Sci. 1985; 311: 617-631.
    • (1985) Philos Trans R Soc Lond B Biol Sci , vol.311 , pp. 617-631
    • Sies, H.1    Cadenas, E.2
  • 22
    • 1642276271 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase on vascular alterations in angiotensin II infused mice
    • Virdis A, Neves MF, Amiri F, Touyz RM, Schiffrin EL. Role of NAD(P)H oxidase on vascular alterations in angiotensin II infused mice. J Hypertens. 2004; 22: 535-542.
    • (2004) J Hypertens , vol.22 , pp. 535-542
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Touyz, R.M.4    Schiffrin, E.L.5
  • 23
    • 3242813758 scopus 로고    scopus 로고
    • Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats
    • Tabet F, Savoia C, Schiffrin EL, Touyz RM. Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats. J Cardiovasc Pharmacol 2004; 44: 200-208.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 200-208
    • Tabet, F.1    Savoia, C.2    Schiffrin, E.L.3    Touyz, R.M.4
  • 24
    • 1642369185 scopus 로고    scopus 로고
    • Reactive oxygen species in vascular biology: Role in arterial hypertension
    • Touyz RM. Reactive oxygen species in vascular biology: role in arterial hypertension. Expert Rev Cardiovasc Ther 2003; 1: 99-106.
    • (2003) Expert Rev Cardiovasc Ther , vol.1 , pp. 99-106
    • Touyz, R.M.1
  • 25
    • 3543011345 scopus 로고    scopus 로고
    • Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension
    • San José G, Moreno MU, Oliván S, et al. Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension. Hypertension 2004; 44: 163-169.
    • (2004) Hypertension , vol.44 , pp. 163-169
    • San-José, G.1    Moreno, M.U.2    Oliván, S.3
  • 26
    • 33745467302 scopus 로고    scopus 로고
    • The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension
    • Moreno MU, San José G, Fortuño A, Beloqui O, Díez J, Zalba G. The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension. J Hypertens 2006; 24: 1299-1306.
    • (2006) J Hypertens , vol.24 , pp. 1299-1306
    • Moreno, M.U.1    San-José, G.2    Fortuño, A.3    Beloqui, O.4    Díez, J.5    Zalba, G.6
  • 27
    • 0344304669 scopus 로고    scopus 로고
    • Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension
    • Touyz RM, Tabet F, Schiffrin EL. Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension. Clin Exp Pharmacol Physiol 2003; 30: 860-866.
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , pp. 860-866
    • Touyz, R.M.1    Tabet, F.2    Schiffrin, E.L.3
  • 28
    • 24344499139 scopus 로고    scopus 로고
    • Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
    • Cai H. Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences. Cardiovasc Res 2005; 68: 26-36.
    • (2005) Cardiovasc Res , vol.68 , pp. 26-36
    • Cai, H.1
  • 29
    • 34447512854 scopus 로고    scopus 로고
    • Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats
    • Kajiya M, Hirota M, Inai Y, et al. Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats. Am J Physiol Heart Circ Physiol 2007; 292: H2737-H2744.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Kajiya, M.1    Hirota, M.2    Inai, Y.3
  • 30
    • 11144356447 scopus 로고    scopus 로고
    • Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species
    • Goyal P, Weissmann N, Grimminger F, et al. Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species. Free Radic Biol Med 2004; 36: 1279-1288.
    • (2004) Free Radic Biol Med , vol.36 , pp. 1279-1288
    • Goyal, P.1    Weissmann, N.2    Grimminger, F.3
  • 31
    • 34250858839 scopus 로고    scopus 로고
    • Reactive oxygen speciesselective regulation of aortic inflammatory gene expression in type 2 diabetes
    • San Martin A, Du P, Dikalova A, et al. Reactive oxygen speciesselective regulation of aortic inflammatory gene expression in type 2 diabetes. Am J Physiol Heart Circ Physiol 2007; 292: H2073-H2082.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • San Martin, A.1    Du, P.2    Dikalova, A.3
  • 32
    • 0038673091 scopus 로고    scopus 로고
    • Antioxidant activities and oxidative stress byproducts in human hypertension
    • Redon J, Oliva MR, Tormos C, et al. Antioxidant activities and oxidative stress byproducts in human hypertension. Hypertension 2003; 41: 1096-10101.
    • (2003) Hypertension , vol.41 , pp. 1096-10101
    • Redon, J.1    Oliva, M.R.2    Tormos, C.3
  • 33
    • 19944403875 scopus 로고    scopus 로고
    • Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice
    • Laude K, Cai H, Fink B, et al. Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. Am J Physiol Heart Circ Physiol 2005; 288: H7-H12.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Laude, K.1    Cai, H.2    Fink, B.3
  • 34
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer binding protein NF-kappa B by a posttranslational mechanism
    • Sen R, Baltimore D. Inducibility of kappa immunoglobulin enhancer binding protein NF-kappa B by a posttranslational mechanism. Cell 1986; 47: 921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 36
    • 0034705372 scopus 로고    scopus 로고
    • Angiotensin II activates nuclear transcription factor kappaB through AT(1) and AT(2) in vascular smooth muscle cells: Molecular mechanisms
    • Ruiz-Ortega M, Lorenzo O, Ruperez M, König S, Wittig B, Egido J. Angiotensin II activates nuclear transcription factor kappaB through AT(1) and AT(2) in vascular smooth muscle cells: molecular mechanisms. Circ Res 2000; 86: 1266-1272.
    • (2000) Circ Res , vol.86 , pp. 1266-1272
    • Ruiz-Ortega, M.1    Lorenzo, O.2    Ruperez, M.3    König, S.4    Wittig, B.5    Egido, J.6
  • 37
    • 2442421008 scopus 로고    scopus 로고
    • Angiotensin II differentially regulates interleukin-1 beta inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: Role of p38 MAPK
    • Jiang B, Xu S, Hou X, Pimentel DR, Cohen RA. Angiotensin II differentially regulates interleukin-1 beta inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK. J Biol Chem 2004; 279: 20363-20368.
    • (2004) J Biol Chem , vol.279 , pp. 20363-20368
    • Jiang, B.1    Xu, S.2    Hou, X.3    Pimentel, D.R.4    Cohen, R.A.5
  • 38
    • 19044369325 scopus 로고    scopus 로고
    • Angiotensin IV activates the nuclear transcription factor-kappaB and related proinflammatory genes in vascular smooth muscle cells
    • Esteban V, Ruperez M, Sanchez-Lopez E, et al. Angiotensin IV activates the nuclear transcription factor-kappaB and related proinflammatory genes in vascular smooth muscle cells. Circ Res 2005; 96: 965-973.
    • (2005) Circ Res , vol.96 , pp. 965-973
    • Esteban, V.1    Ruperez, M.2    Sanchez-Lopez, E.3
  • 39
    • 0036903593 scopus 로고    scopus 로고
    • NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells
    • Zahradka P, Werner JP, Buhay S, Litchie B, Helwer G, Thomas S. NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells. J Mol Cell Cardiol 2002; 34: 1609-1621.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1609-1621
    • Zahradka, P.1    Werner, J.P.2    Buhay, S.3    Litchie, B.4    Helwer, G.5    Thomas, S.6
  • 40
    • 0022067275 scopus 로고
    • Characterization of a coronary vasoconstrictor produced by cultured endothelial cells
    • Hickey KA, Rubanyi G, Paul RJ, Highsmith, RF. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 1985; 248: C550-C556.
    • (1985) Am J Physiol , vol.248
    • Hickey, K.A.1    Rubanyi, G.2    Paul, R.J.3    Highsmith, R.F.4
  • 41
    • 0036468709 scopus 로고    scopus 로고
    • ET(A) and ET(B)-receptors modulate the proliferation of human pulmonary artery smooth muscle cells
    • Davie N, Haleen SJ, Upton PD, et al. ET(A) and ET(B)-receptors modulate the proliferation of human pulmonary artery smooth muscle cells. Am J Respir Crit Care Med 2002; 165: 398-405.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 398-405
    • Davie, N.1    Haleen, S.J.2    Upton, P.D.3
  • 42
    • 20444488435 scopus 로고    scopus 로고
    • Vascular enthothelin in hypertension
    • Schiffrin EL. Vascular enthothelin in hypertension. Vascul Pharmacol 2005; 43: 19-29.
    • (2005) Vascul Pharmacol , vol.43 , pp. 19-29
    • Schiffrin, E.L.1
  • 43
    • 43449111223 scopus 로고    scopus 로고
    • Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells
    • Amiri F, Paradis P, Reudelhuber TL, Schiffrin EL. Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells. J Hypertens 2008; 26: 1102-1109.
    • (2008) J Hypertens , vol.26 , pp. 1102-1109
    • Amiri, F.1    Paradis, P.2    Reudelhuber, T.L.3    Schiffrin, E.L.4
  • 44
    • 0037161360 scopus 로고    scopus 로고
    • Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of Creactive protein
    • Verma S, Li SH, Badiwala MV, et al. Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of Creactive protein. Circulation 2002; 105: 1890-1896.
    • (2002) Circulation , vol.105 , pp. 1890-1896
    • Verma, S.1    Li, S.H.2    Badiwala, M.V.3
  • 45
    • 1442299098 scopus 로고    scopus 로고
    • In-vivo interaction of nitric oxide and endothelin
    • Hocher B, Schwarz A, Slowinski T, et al. In-vivo interaction of nitric oxide and endothelin. J Hypertens 2004; 22: 111-119.
    • (2004) J Hypertens , vol.22 , pp. 111-119
    • Hocher, B.1    Schwarz, A.2    Slowinski, T.3
  • 46
    • 28144445338 scopus 로고    scopus 로고
    • Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin- (1-7) in regulation of cardiovascular function
    • Ferrario CM, Trask AJ, Jessup JA. Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin- (1-7) in regulation of cardiovascular function. Am J Physiol Heart Circ Physiol 2005; 89: H2281-H2290.
    • (2005) Am J Physiol Heart Circ Physiol , vol.89
    • Ferrario, C.M.1    Trask, A.J.2    Jessup, J.A.3
  • 47
    • 4444238183 scopus 로고    scopus 로고
    • Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling
    • Zhao Q, Ishibashi M, Hiasa K, Tan C, Takeshita A, Egashira K. Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling. Hypertension 2004; 44: 264-270.
    • (2004) Hypertension , vol.44 , pp. 264-270
    • Zhao, Q.1    Ishibashi, M.2    Hiasa, K.3    Tan, C.4    Takeshita, A.5    Egashira, K.6
  • 48
    • 4344682953 scopus 로고    scopus 로고
    • Angiotensin receptor blockade decreases markers of vascular inflammation
    • Graninger M, Reiter R, Drucker C, Minar E, Jilma B. Angiotensin receptor blockade decreases markers of vascular inflammation. J Cardiovasc Pharmacol 2004; 44(3): 335-339.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.3 , pp. 335-339
    • Graninger, M.1    Reiter, R.2    Drucker, C.3    Minar, E.4    Jilma, B.5
  • 49
    • 64249148490 scopus 로고    scopus 로고
    • Neutrophil adhesion and activation under flow
    • Zarbock A, Ley K. Neutrophil adhesion and activation under flow. Microcirculation 2009; 16: 31-42.
    • (2009) Microcirculation , vol.16 , pp. 31-42
    • Zarbock, A.1    Ley, K.2
  • 50
    • 0036433105 scopus 로고    scopus 로고
    • Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney
    • Ruiz-Ortega M, Ruperez M, Lorenzo O, et al. Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. Kidney Int Suppl 2002; 82: S12-S22.
    • (2002) Kidney Int Suppl , vol.82
    • Ruiz-Ortega, M.1    Ruperez, M.2    Lorenzo, O.3
  • 51
    • 0035571072 scopus 로고    scopus 로고
    • Rho-kinase mediates angiotensin- II monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells
    • Funakoshi Y, Ichiki T, Shimikawa K. Rho-kinase mediates angiotensin- II monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension 2001; 38: 100-104.
    • (2001) Hypertension , vol.38 , pp. 100-104
    • Funakoshi, Y.1    Ichiki, T.2    Shimikawa, K.3
  • 52
    • 0037426399 scopus 로고    scopus 로고
    • C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle
    • Wang CH, Li SH, Weisel RD, et al. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation 2003; 107: 1783-1790.
    • (2003) Circulation , vol.107 , pp. 1783-1790
    • Wang, C.H.1    Li, S.H.2    Weisel, R.D.3
  • 53
    • 26244440599 scopus 로고    scopus 로고
    • Complement activation in angiotensin II-induced organ damage
    • Shagdarsuren E, Wellner M, Braesen JH, et al. Complement activation in angiotensin II-induced organ damage. Circ Res 2005; 97(7): 716-724.
    • (2005) Circ Res , vol.97 , Issue.7 , pp. 716-724
    • Shagdarsuren, E.1    Wellner, M.2    Braesen, J.H.3
  • 54
    • 39149136199 scopus 로고    scopus 로고
    • Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB
    • Rose P, Bond J, Tighe S, et al. Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB. Am J Physiol Heart Circ Physiol 2008; 294: H1075-H1085.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Rose, P.1    Bond, J.2    Tighe, S.3
  • 55
    • 0141792689 scopus 로고    scopus 로고
    • Regulation of tumor necrosis factor- alpha promoter by angiotensin II and lippolysaccharide in cardiac fibroblast: Different cis-acting promoter sequence and transcriptional factors
    • Sato H, Watanabe A, Tanaka T. Regulation of tumor necrosis factor- alpha promoter by angiotensin II and lippolysaccharide in cardiac fibroblast: different cis-acting promoter sequence and transcriptional factors. J Moll Cell Cardiol 2003; 35: 1197-1205.
    • (2003) J Moll Cell Cardiol , vol.35 , pp. 1197-1205
    • Sato, H.1    Watanabe, A.2    Tanaka, T.3
  • 56
    • 0037675052 scopus 로고    scopus 로고
    • The role of angiotensin II in regulating vascular structural and functional changes in hypertension
    • Touyz RM. The role of angiotensin II in regulating vascular structural and functional changes in hypertension. Curr Hypertens Rep 2003; 5: 155-164.
    • (2003) Curr Hypertens Rep , vol.5 , pp. 155-164
    • Touyz, R.M.1
  • 57
    • 2542446284 scopus 로고    scopus 로고
    • Stimulation of GMP production via AT2 and B2 receptors in the pressureoverloaded aorta after banding
    • Hiyoshi H, Yayama K, Takano M, Okamoto H. Stimulation of GMP production via AT2 and B2 receptors in the pressureoverloaded aorta after banding. Hypertension. 2004; 43: 1258-1263.
    • (2004) Hypertension , vol.43 , pp. 1258-1263
    • Hiyoshi, H.1    Yayama, K.2    Takano, M.3    Okamoto, H.4
  • 59
    • 0034714978 scopus 로고    scopus 로고
    • The multiple actions of angiotensin II in atherosclerosis
    • Schmidt-Ott KM, Kagiyama S, Phillips MI. The multiple actions of angiotensin II in atherosclerosis. Regul Pept 2000; 93(1/3): 65-77.
    • (2000) Regul Pept , vol.93 , Issue.1-3 , pp. 65-77
    • Schmidt-Ott, K.M.1    Kagiyama, S.2    Phillips, M.I.3
  • 60
    • 26244446955 scopus 로고    scopus 로고
    • Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin IIinfused macrophage colony-stimulating factor-deficient mice: Evidence for a role in inflammation in angiotensin induced vascular injury
    • De Ciuceis C, Amiri F, Brassard P, Endemann DH, Touyz R M, Schiffrin EL. Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin IIinfused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin induced vascular injury. Arterioscler. Thromb Vasc Biol 2005; 25: 2106-2113.
    • (2005) Arterioscler. Thromb Vasc Biol , vol.25 , pp. 2106-2113
    • de Ciuceis, C.1    Amiri, F.2    Brassard, P.3    Endemann, D.H.4    Touyz, R.M.5    Schiffrin, E.L.6
  • 61
    • 0034705472 scopus 로고    scopus 로고
    • Cytokine actions of angiotensin II
    • Sadoshima J. Cytokine actions of angiotensin II. Circ Res 2000; 86(12): 1187-1189.
    • (2000) Circ Res , vol.86 , Issue.12 , pp. 1187-1189
    • Sadoshima, J.1
  • 62
    • 0035838423 scopus 로고    scopus 로고
    • Aldosterone induces angiotensin- converting enzyme gene expression in cultured neonatal rat cardiocytes
    • Harada E, Yoshimura M, Yasue H, et al. Aldosterone induces angiotensin- converting enzyme gene expression in cultured neonatal rat cardiocytes. Circulation 2001; 104: 137-139.
    • (2001) Circulation , vol.104 , pp. 137-139
    • Harada, E.1    Yoshimura, M.2    Yasue, H.3
  • 63
    • 21244458789 scopus 로고    scopus 로고
    • Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation
    • Joffe HV, Alder KA. Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation. Heart Failure Rev 2005; 10: 31-37.
    • (2005) Heart Failure Rev , vol.10 , pp. 31-37
    • Joffe, H.V.1    Alder, K.A.2
  • 64
    • 0031600240 scopus 로고    scopus 로고
    • Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats
    • Rocha R, Chander PC, Khanna K, Zuckerman A, Stier Jr CT. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 1998; 31: 451-458.
    • (1998) Hypertension , vol.31 , pp. 451-458
    • Rocha, R.1    Chander, P.C.2    Khanna, K.3    Zuckerman, A.4    Stier, C.T.5
  • 65
    • 0035090207 scopus 로고    scopus 로고
    • Mineralocorticoid receptor affects AP-1 and nuclear factor-κB activation in angiotensin IIinduced cardiac injury
    • Fiebeler A, Schmidt F, Muller DN, et al. Mineralocorticoid receptor affects AP-1 and nuclear factor-κB activation in angiotensin IIinduced cardiac injury. Hypertension 2001; 37: 787-793.
    • (2001) Hypertension , vol.37 , pp. 787-793
    • Fiebeler, A.1    Schmidt, F.2    Muller, D.N.3
  • 66
    • 0036175568 scopus 로고    scopus 로고
    • Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCAsalt hypertensive rats: Role of ETA receptors
    • Ammarguellat FZ, Gannon PO, Amiri F, Schiffrin EL. Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCAsalt hypertensive rats: role of ETA receptors. Hypertension 2002; 39: 679-684.
    • (2002) Hypertension , vol.39 , pp. 679-684
    • Ammarguellat, F.Z.1    Gannon, P.O.2    Amiri, F.3    Schiffrin, E.L.4
  • 67
    • 0038141826 scopus 로고    scopus 로고
    • Endothelin antagonism on aldosteroneinduced oxidative stress and vascular remodeling
    • Pu Q, Neves MF, Virdis A, Touyz R, Schiffrin EL. Endothelin antagonism on aldosteroneinduced oxidative stress and vascular remodeling. Hypertension 2003; 42: 49-55
    • (2003) Hypertension , vol.42 , pp. 49-55
    • Pu, Q.1    Neves, M.F.2    Virdis, A.3    Touyz, R.4    Schiffrin, E.L.5
  • 68
    • 0036791717 scopus 로고    scopus 로고
    • Spironolactone improves angiotensin-induced vascular changes and oxidative stress
    • Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL. Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension 2002; 40: 504-510.
    • (2002) Hypertension , vol.40 , pp. 504-510
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Viel, E.4    Touyz, R.M.5    Schiffrin, E.L.6
  • 69
    • 21744459701 scopus 로고    scopus 로고
    • Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats
    • Blanco-Rivero J, Cachofeiro V, Lahera V, et al. Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats. Hypertension 2005; 46: 107-112.
    • (2005) Hypertension , vol.46 , pp. 107-112
    • Blanco-Rivero, J.1    Cachofeiro, V.2    Lahera, V.3
  • 70
    • 33646692656 scopus 로고    scopus 로고
    • Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation
    • Suzuki J, Iwai M, Mogi M, et al. Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation. Arterioscler Thromb Vasc Biol 2006; 26: 917-921.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 917-921
    • Suzuki, J.1    Iwai, M.2    Mogi, M.3
  • 71
    • 33644895071 scopus 로고    scopus 로고
    • Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy
    • CIHR Multidisciplinary Research Group on Hypertension
    • Neves MF, Amiri F, Virdis A, Diep QN, Schiffrin EL. CIHR Multidisciplinary Research Group on Hypertension. Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy. Can J Physiol Pharmacol 2005; 83: 999-1006.
    • (2005) Can J Physiol Pharmacol , vol.83 , pp. 999-1006
    • Neves, M.F.1    Amiri, F.2    Virdis, A.3    Diep, Q.N.4    Schiffrin, E.L.5
  • 72
    • 38549092093 scopus 로고    scopus 로고
    • Aldosterone and vascular inflammation
    • Brown NJ. Aldosterone and vascular inflammation. Hypertension 2008; 51: 161-167.
    • (2008) Hypertension , vol.51 , pp. 161-167
    • Brown, N.J.1
  • 73
    • 34648835099 scopus 로고    scopus 로고
    • Stress, inflammation, and hypertension
    • Pickering TG. Stress, inflammation, and hypertension. J Clin Hypertens (Greenwich) 2007; 9: 567-571.
    • (2007) J Clin Hypertens (Greenwich) , vol.9 , pp. 567-571
    • Pickering, T.G.1
  • 74
    • 33751110231 scopus 로고    scopus 로고
    • Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptordependent mechanism
    • Luther JM, Gainer JV, Murphey LJ, et al. Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptordependent mechanism. Hypertension 2006; 48: 1050-1057.
    • (2006) Hypertension , vol.48 , pp. 1050-1057
    • Luther, J.M.1    Gainer, J.V.2    Murphey, L.J.3
  • 75
    • 33744954417 scopus 로고    scopus 로고
    • Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
    • Takebayashi K, Matsumoto S, Aso Y, Inukai T. Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. J Clin Endocrinol Metab 2006; 91: 2214-2217.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2214-2217
    • Takebayashi, K.1    Matsumoto, S.2    Aso, Y.3    Inukai, T.4
  • 77
    • 0033672864 scopus 로고    scopus 로고
    • An overview of antihypertensive therapy in the 20th century
    • Piepho RW, Beal J. An overview of antihypertensive therapy in the 20th century. J Clin Pharmacol 2000; 40: 967-977.
    • (2000) J Clin Pharmacol , vol.40 , pp. 967-977
    • Piepho, R.W.1    Beal, J.2
  • 78
    • 33847704535 scopus 로고    scopus 로고
    • Direct renin inhibition-a new way of targeting the renin system
    • Brown MJ. Direct renin inhibition-a new way of targeting the renin system. J Renin Angiotensin Aldosterone Syst 2006; 7(suppl 2): S7-S11.
    • (2006) J Renin Angiotensin Aldosterone Syst , vol.7 , Issue.SUPPL. 2
    • Brown, M.J.1
  • 79
    • 0030293795 scopus 로고    scopus 로고
    • Angiotensinogen: Molecular biology, biochemistry and physiology
    • Morgan L, Broughton PF, Kalsheker N. Angiotensinogen: molecular biology, biochemistry and physiology. Int J Biochem Cell Biol 1996; 28: 1211-1222.
    • (1996) Int J Biochem Cell Biol , vol.28 , pp. 1211-1222
    • Morgan, L.1    Broughton, P.F.2    Kalsheker, N.3
  • 80
    • 0037667643 scopus 로고    scopus 로고
    • Newly recognized components of the reninangiotensin system: Potential roles in cardiovascular and renal regulation
    • Carey RM, Siragy HM. Newly recognized components of the reninangiotensin system: potential roles in cardiovascular and renal regulation. Endocr Rev 2003; 24: 261-271.
    • (2003) Endocr Rev , vol.24 , pp. 261-271
    • Carey, R.M.1    Siragy, H.M.2
  • 81
    • 33644970894 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 and angiotensin-(1-7): An evolving story in cardiovascular regulation
    • Ferraro CM. Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulation. Hypertension 2006; 47(3): 515-521.
    • (2006) Hypertension , vol.47 , Issue.3 , pp. 515-521
    • Ferraro, C.M.1
  • 82
    • 34249100267 scopus 로고    scopus 로고
    • The role of angiotensin AT1 receptor-associated protein in renin-angiotensin system regulation and function
    • Tamura K, Tanaka Y, Tsurumi Y, et al. The role of angiotensin AT1 receptor-associated protein in renin-angiotensin system regulation and function. Curr Hypertens Rep 2007; 9(2): 121-127.
    • (2007) Curr Hypertens Rep , vol.9 , Issue.2 , pp. 121-127
    • Tamura, K.1    Tanaka, Y.2    Tsurumi, Y.3
  • 83
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer J-D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109: 1417-1427.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.-D.6
  • 84
    • 0036847322 scopus 로고    scopus 로고
    • New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone
    • Funder JW. New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone. Am Heart J 2002; 144: S8-S11.
    • (2002) Am Heart J , vol.144
    • Funder, J.W.1
  • 85
    • 0033054630 scopus 로고    scopus 로고
    • Increased chymase-dependent angiotensin II formation in human atherosclerotic aorta
    • Ihara M, Urata H, Kinoshita A, et al. Increased chymase-dependent angiotensin II formation in human atherosclerotic aorta. Hypertension 1999; 33: 1399-1405.
    • (1999) Hypertension , vol.33 , pp. 1399-1405
    • Ihara, M.1    Urata, H.2    Kinoshita, A.3
  • 86
    • 0031688757 scopus 로고    scopus 로고
    • Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system
    • Hollenberg NK, Fisher NDL, Price DA. Pathways for angiotensin II generation in intact human tissue: evidence from comparative pharmacological interruption of the renin system. Hypertension 1998; 32: 387-392.
    • (1998) Hypertension , vol.32 , pp. 387-392
    • Hollenberg, N.K.1    Fisher, N.D.L.2    Price, D.A.3
  • 87
    • 0025239660 scopus 로고
    • Angiotensin II-forming pathways in normal and failing human hearts
    • Urata H, Healy B, Stewart RW, Bumpus FM, Husain A. Angiotensin II-forming pathways in normal and failing human hearts. Circ Res 1990; 66: 883-890.
    • (1990) Circ Res , vol.66 , pp. 883-890
    • Urata, H.1    Healy, B.2    Stewart, R.W.3    Bumpus, F.M.4    Husain, A.5
  • 88
    • 0031017144 scopus 로고    scopus 로고
    • Functional and biochemical analysis of angiotensin II-forming pathways in the human heart
    • Wolny A, Clozel JP, Rein J, et al. Functional and biochemical analysis of angiotensin II-forming pathways in the human heart. Circ Res 1997; 80: 219-227.
    • (1997) Circ Res , vol.80 , pp. 219-227
    • Wolny, A.1    Clozel, J.P.2    Rein, J.3
  • 89
    • 20044392897 scopus 로고    scopus 로고
    • Rethinking the renin-angiotensin system and its role in cardiovascular regulation
    • Pagliaro P, Penna C. Rethinking the renin-angiotensin system and its role in cardiovascular regulation. Cardiovasc Drugs Ther 2005; 19: 77-87.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 77-87
    • Pagliaro, P.1    Penna, C.2
  • 90
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local reninangiotensin systems
    • Paul M, Poyan Mehr A, Kreutz R. Physiology of local reninangiotensin systems. Physiol Rev 2006; 86: 747-803.
    • (2006) Physiol Rev , vol.86 , pp. 747-803
    • Paul, M.1    Poyan, M.A.2    Kreutz, R.3
  • 91
    • 0028229413 scopus 로고
    • Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis
    • Danser AH, van Kats JP, Admiraal PJ, et al. Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis. Hypertension 1994; 24: 37-48.
    • (1994) Hypertension , vol.24 , pp. 37-48
    • Danser, A.H.1    van Kats, J.P.2    Admiraal, P.J.3
  • 92
    • 76549135696 scopus 로고    scopus 로고
    • Brain renin-angiotensinaldosterone system and ventricular remodeling after myocardial infarct: A review
    • 2009 Dec
    • Westcott KV, Huang BS, Leenen FH. Brain renin-angiotensinaldosterone system and ventricular remodeling after myocardial infarct: a review. Can J Physiol Pharmacol 2009 Dec; 87(12): 979-988.
    • Can J Physiol Pharmacol , vol.87 , Issue.12 , pp. 979-988
    • Westcott, K.V.1    Huang, B.S.2    Leenen, F.H.3
  • 93
    • 62949166989 scopus 로고    scopus 로고
    • Angiotensin II regulation of adrenocortical gene transcription
    • 2009 Apr 29;
    • Nogueira EF, Bollag WB, Rainey WE. Angiotensin II regulation of adrenocortical gene transcription. Mol Cell Endocrinol 2009 Apr 29; 302(2): 230-236
    • Mol Cell Endocrinol , vol.302 , Issue.2 , pp. 230-236
    • Nogueira, E.F.1    Bollag, W.B.2    Rainey, W.E.3
  • 94
    • 62949204377 scopus 로고    scopus 로고
    • Mechanisms of angiotensin IImediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells
    • Szekeres M, Turu G, Orient A, et al. Mechanisms of angiotensin IImediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells. Mol Cell Endocrinol 2009; 302(2): 244-253.
    • (2009) Mol Cell Endocrinol , vol.302 , Issue.2 , pp. 244-253
    • Szekeres, M.1    Turu, G.2    Orient, A.3
  • 96
    • 10044243902 scopus 로고    scopus 로고
    • The clinical use of angiotensinconverting enzyme inhibitors
    • Wong J, Patel RA, Kowey PR. The clinical use of angiotensinconverting enzyme inhibitors. Prog Cardiovasc Dis 2004; 47: 116-130.
    • (2004) Prog Cardiovasc Dis , vol.47 , pp. 116-130
    • Wong, J.1    Patel, R.A.2    Kowey, P.R.3
  • 97
    • 23944441082 scopus 로고    scopus 로고
    • Renin-angiotensin system modulation: The weight of evidence
    • Brown B, Hall AS. Renin-angiotensin system modulation: the weight of evidence. Am J Hypertens. 2005; 18(9 pt 2): 127S-33S.
    • (2005) Am J Hypertens , vol.18 , Issue.9 Pt 2
    • Brown, B.1    Hall, A.S.2
  • 98
    • 4143126680 scopus 로고    scopus 로고
    • Expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease
    • for the Task Force on ACE-inhibitors of the European Society of Cardiology
    • Lopez-Sendon J, Swedberg K, McMurray J, et al. for the Task Force on ACE-inhibitors of the European Society of Cardiology. Expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease. Eur Heart J 2004; 25: 1454-1470.
    • (2004) Eur Heart J , vol.25 , pp. 1454-1470
    • Lopez-Sendon, J.1    Swedberg, K.2    McMurray, J.3
  • 99
    • 0028914059 scopus 로고
    • Escape of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: Implications for therapy
    • Pitt B. "Escape" of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: implications for therapy. Cardiovasc Drugs Ther 1995; 9: 145-149.
    • (1995) Cardiovasc Drugs Ther , vol.9 , pp. 145-149
    • Pitt, B.1
  • 100
    • 0021235477 scopus 로고
    • Hormonal and metabolic effects of angiotensin converting enzyme inhibitors: Possible differences between enalapril and captopril
    • Atlas SA, Case DB, Yu ZY, Laragh JH. Hormonal and metabolic effects of angiotensin converting enzyme inhibitors: possible differences between enalapril and captopril. Am J Med 1984; 77: 13-17.
    • (1984) Am J Med , vol.77 , pp. 13-17
    • Atlas, S.A.1    Case, D.B.2    Yu, Z.Y.3    Laragh, J.H.4
  • 101
    • 15844368318 scopus 로고    scopus 로고
    • Effect of the angiotensinconverting- enzyme inhibitor benazepril on the progression of chronic renal insufficiency
    • Maschio G, Alberti D, Janin G, et al. Effect of the angiotensinconverting- enzyme inhibitor benazepril on the progression of chronic renal insufficiency. N Engl J Med. 1996; 334: 939-945.
    • (1996) N Engl J Med , vol.334 , pp. 939-945
    • Maschio, G.1    Alberti, D.2    Janin, G.3
  • 102
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • for the collaborative study group
    • Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. for the collaborative study group. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329: 1456-1462.
    • (1993) N Engl J Med , vol.329 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 103
    • 0024311623 scopus 로고
    • The safety of ACE inhibitors for the treatment of hypertension and congestive heart failure
    • Frank GJ. The safety of ACE inhibitors for the treatment of hypertension and congestive heart failure. Cardiology 1989; 76 Suppl 2: 56-67.
    • (1989) Cardiology , vol.76 , Issue.SUPPL. 2 , pp. 56-67
    • Frank, G.J.1
  • 104
    • 0033770480 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme inhibitor prevents age-related endothelial dysfunction
    • Goto K, Fujii K, Onaka U, Abe I, Fujishima M. Angiotensinconverting enzyme inhibitor prevents age-related endothelial dysfunction. Hypertension 2000; 36(4): 581-587.
    • (2000) Hypertension , vol.36 , Issue.4 , pp. 581-587
    • Goto, K.1    Fujii, K.2    Onaka, U.3    Abe, I.4    Fujishima, M.5
  • 105
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • The SOLVD Investigators
    • The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 1992; 327: 685-691.
    • (1992) N Engl J Med , vol.327 , pp. 685-691
  • 106
    • 0025913812 scopus 로고
    • The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991; 325: 293-302.
    • (1991) N Engl J Med , vol.325 , pp. 293-302
  • 107
    • 0028273258 scopus 로고
    • GISSI-3: Effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico. GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Lancet 1994; 343: 1115-1122.
    • (1994) Lancet , vol.343 , pp. 1115-1122
  • 108
    • 0028932732 scopus 로고
    • ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction
    • ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group
    • ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. Lancet 1995; 345: 669-685.
    • (1995) Lancet , vol.345 , pp. 669-685
  • 109
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators
    • Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992; 327: 669-677
    • (1992) N Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3
  • 110
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
    • The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators
    • The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 1993; 342: 821-828.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 111
    • 0042330455 scopus 로고    scopus 로고
    • Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: Randomised, doubleblind, placebo-controlled, multicentre trial (the EUROPA study)
    • EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease [EUROPA] Investigators
    • Fox KM; EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease [EUROPA] Investigators. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, doubleblind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003; 362: 782-788.
    • (2003) Lancet , vol.362 , pp. 782-788
    • Fox, K.M.1
  • 112
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
    • for The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. for The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000; 342: 145-153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 113
    • 0033034404 scopus 로고    scopus 로고
    • Effect of angiotensin converting- enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial
    • Hansson L, Lindholm LH, Niskanen L, et al. Effect of angiotensin converting- enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. Lancet 1999; 353: 611-616.
    • (1999) Lancet , vol.353 , pp. 611-616
    • Hansson, L.1    Lindholm, L.H.2    Niskanen, L.3
  • 114
    • 0037432313 scopus 로고    scopus 로고
    • Enalapril reduces the incidence of diabetes in patients with chronic heart failure: Insight from the Studies Of Left Ventricular Dysfunction (SOLVD)
    • Vermes E, Ducharme A, Bourassa MG, Lessard M, White M, Tardif JC. Enalapril reduces the incidence of diabetes in patients with chronic heart failure: insight from the Studies Of Left Ventricular Dysfunction (SOLVD). Circulation 2003; 107: 1291-1296.
    • (2003) Circulation , vol.107 , pp. 1291-1296
    • Vermes, E.1    Ducharme, A.2    Bourassa, M.G.3    Lessard, M.4    White, M.5    Tardif, J.C.6
  • 115
    • 19644400972 scopus 로고    scopus 로고
    • Angiotensin-converting-enzyme inhibition in stable coronary artery disease
    • The PEACE Trial Investigators
    • The PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351: 2058-2068.
    • (2004) N Engl J Med , vol.351 , pp. 2058-2068
  • 116
    • 25844476905 scopus 로고    scopus 로고
    • Angiotensin receptor blockers: Therapeutic targets and cardiovascular protection
    • Ruilope LM, Rosei EA, Bakris GL, et al. Angiotensin receptor blockers: therapeutic targets and cardiovascular protection. Blood Press 2005; 14: 196-209.
    • (2005) Blood Press , vol.14 , pp. 196-209
    • Ruilope, L.M.1    Rosei, E.A.2    Bakris, G.L.3
  • 118
    • 0035131472 scopus 로고    scopus 로고
    • Irbesartan, an angiotensin type 1 receptor inhibitor, regulates markers of inflammation in patients with premature atherosclerosis
    • Navalkar S, Parthasarathy S, Santanam N, Khan BV. Irbesartan, an angiotensin type 1 receptor inhibitor, regulates markers of inflammation in patients with premature atherosclerosis. J Am Coll Cardiol 2001; 37: 440-444.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 440-444
    • Navalkar, S.1    Parthasarathy, S.2    Santanam, N.3    Khan, B.V.4
  • 119
    • 67449088325 scopus 로고    scopus 로고
    • Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: The MITEC study
    • Baguet JP, Asmar R, Valensi P, Nisse-Durgeat S, Mallion JM. Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study. Vasc Health Risk Manag 2009; 5: 175-183.
    • (2009) Vasc Health Risk Manag , vol.5 , pp. 175-183
    • Baguet, J.P.1    Asmar, R.2    Valensi, P.3    Nisse-Durgeat, S.4    Mallion, J.M.5
  • 120
    • 59349086385 scopus 로고    scopus 로고
    • Cardiovascular outcomes in high-risk patients without heart failure treated with ARBs: A systematic review and meta-analysis
    • Al Khalaf MM, Thalib L, Doi SA. Cardiovascular outcomes in high-risk patients without heart failure treated with ARBs: a systematic review and meta-analysis. Am J Cardiovasc Drugs 2009; 9: 29-43.
    • (2009) Am J Cardiovasc Drugs , vol.9 , pp. 29-43
    • Al-Khalaf, M.M.1    Thalib, L.2    Doi, S.A.3
  • 121
    • 34250901060 scopus 로고    scopus 로고
    • Prevention of stroke and myocardial infarction by amlodipine and angiotensin receptor blockers: A quantitative overview
    • Wang JG, Li Y, Franklin SS, Safar M. Prevention of stroke and myocardial infarction by amlodipine and angiotensin receptor blockers: a quantitative overview. Hypertension 2007; 50: 181-188.
    • (2007) Hypertension , vol.50 , pp. 181-188
    • Wang, J.G.1    Li, Y.2    Franklin, S.S.3    Safar, M.4
  • 122
    • 38049139424 scopus 로고    scopus 로고
    • Metaanalysis: Effect of monotherapy and combination therapy with inhibitors of the renin angiotensin system on proteinuria in renal disease
    • Kunz R, Friedrich C, Wolbers M, Mann JF. Metaanalysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin system on proteinuria in renal disease. Ann Intern Med 2008; 148: 30-48.
    • (2008) Ann Intern Med , vol.148 , pp. 30-48
    • Kunz, R.1    Friedrich, C.2    Wolbers, M.3    Mann, J.F.4
  • 123
    • 47749118322 scopus 로고    scopus 로고
    • Effects of renin-angiotensin system blockers on renal outcomes and all-cause mortality in patients with diabetic nephropathy: An updated metaanalysis
    • Sarafidis PA, Stafylas PC, Kanaki AI, Lasaridis AN. Effects of renin-angiotensin system blockers on renal outcomes and all-cause mortality in patients with diabetic nephropathy: an updated metaanalysis. Am J Hypertens 2008; 21: 922-929.
    • (2008) Am J Hypertens , vol.21 , pp. 922-929
    • Sarafidis, P.A.1    Stafylas, P.C.2    Kanaki, A.I.3    Lasaridis, A.N.4
  • 124
    • 34247640280 scopus 로고    scopus 로고
    • Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: A meta-analysis
    • Jennings DL, Kalus JS, Coleman CI, Manierski C, Yee J. Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta-analysis. Diabet Med 2007; 24: 486-493.
    • (2007) Diabet Med , vol.24 , pp. 486-493
    • Jennings, D.L.1    Kalus, J.S.2    Coleman, C.I.3    Manierski, C.4    Yee, J.5
  • 125
    • 41149101190 scopus 로고    scopus 로고
    • Safety and tolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensinconverting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: A systematic review and meta-analysis of randomized controlled trials
    • Lakhdar R, Al-Mallah MH, Lanfear DE. Safety and tolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensinconverting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: a systematic review and meta-analysis of randomized controlled trials. J Card Fail 2008; 14: 181-188.
    • (2008) J Card Fail , vol.14 , pp. 181-188
    • Lakhdar, R.1    Al-Mallah, M.H.2    Lanfear, D.E.3
  • 126
    • 70449730792 scopus 로고    scopus 로고
    • Regression of left ventricular mass by antihypertensive treatment: A meta-analysis of randomized comparative studies
    • Fagard RH, Celis H, Thijs L, Wouters S. Regression of left ventricular mass by antihypertensive treatment: a meta-analysis of randomized comparative studies. Hypertension 2009; 54: 1084-1091.
    • (2009) Hypertension , vol.54 , pp. 1084-1091
    • Fagard, R.H.1    Celis, H.2    Thijs, L.3    Wouters, S.4
  • 127
    • 1242272211 scopus 로고    scopus 로고
    • Metaanalyses of mortality and morbidity effects of an angiotensin receptor blocker in patients with chronic heart failure already receiving an ACE inhibitor (alone or with a beta-blocker)
    • Dimopoulos K, Salukhe TV, Coats AJ, Mayet J, Piepoli M, Francis DP. Metaanalyses of mortality and morbidity effects of an angiotensin receptor blocker in patients with chronic heart failure already receiving an ACE inhibitor (alone or with a beta-blocker). Int J Cardiol 2004; 93: 105-111.
    • (2004) Int J Cardiol , vol.93 , pp. 105-111
    • Dimopoulos, K.1    Salukhe, T.V.2    Coats, A.J.3    Mayet, J.4    Piepoli, M.5    Francis, D.P.6
  • 128
    • 0036839716 scopus 로고    scopus 로고
    • Angiotensin receptor blockers: How important is selectivity?
    • Siragy HM. Angiotensin receptor blockers: how important is selectivity? Am J Hypertens 2002; 15: 1006-1014.
    • (2002) Am J Hypertens , vol.15 , pp. 1006-1014
    • Siragy, H.M.1
  • 129
    • 0036429265 scopus 로고    scopus 로고
    • The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy
    • Elmfeldt D, Olofsson B, Meredith P. The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy. Blood Press 2002; 11: 293-301.
    • (2002) Blood Press , vol.11 , pp. 293-301
    • Elmfeldt, D.1    Olofsson, B.2    Meredith, P.3
  • 130
    • 22244443855 scopus 로고    scopus 로고
    • Comparison of the effects of quinapril and losartan on carotid artery intima-media thickness in patients with mild-to-moderate arterial hypertension
    • Uchiyama-Tanaka Y, Mori Y, Kishimoto N, et al. Comparison of the effects of quinapril and losartan on carotid artery intima-media thickness in patients with mild-to-moderate arterial hypertension. Kidney Blood Press Res 2005; 28: 111-116.
    • (2005) Kidney Blood Press Res , vol.28 , pp. 111-116
    • Uchiyama-Tanaka, Y.1    Mori, Y.2    Kishimoto, N.3
  • 131
    • 33947119222 scopus 로고    scopus 로고
    • Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension
    • Flammer AJ, Hermann F, Wiesli P, et al. Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension. J Hypertens 2007; 25: 785-791.
    • (2007) J Hypertens , vol.25 , pp. 785-791
    • Flammer, A.J.1    Hermann, F.2    Wiesli, P.3
  • 132
    • 25444460810 scopus 로고    scopus 로고
    • Low doses of losartan and trandolapril improve arterial stiffness in hemodialysis patients
    • Ichihara A, Hayashi M, Kaneshiro Y, et al. Low doses of losartan and trandolapril improve arterial stiffness in hemodialysis patients. Am J Kidney Dis 2005; 45: 866-874.
    • (2005) Am J Kidney Dis , vol.45 , pp. 866-874
    • Ichihara, A.1    Hayashi, M.2    Kaneshiro, Y.3
  • 133
    • 0034160475 scopus 로고    scopus 로고
    • Reduction of resistance artery stiffness by treatment with the AT(1)-receptor antagonist losartan in essential hypertension
    • Park JB, Intengan HD, Schiffrin EL. Reduction of resistance artery stiffness by treatment with the AT(1)-receptor antagonist losartan in essential hypertension. J Renin Angiotensin Aldosterone Syst 2000; 1: 40-45.
    • (2000) J Renin Angiotensin Aldosterone Syst , vol.1 , pp. 40-45
    • Park, J.B.1    Intengan, H.D.2    Schiffrin, E.L.3
  • 134
    • 33846438982 scopus 로고    scopus 로고
    • Reduction in arterial stiffness with angiotensin II antagonism and converting enzyme inhibition. A comparative study among Malay hypertensive subjects with a known genetic profile
    • Rehman A, Ismail SB, Naing L, Roshan TM, Rahman AR. Reduction in arterial stiffness with angiotensin II antagonism and converting enzyme inhibition. A comparative study among Malay hypertensive subjects with a known genetic profile. Am J Hypertens 2007; 20: 184-189.
    • (2007) Am J Hypertens , vol.20 , pp. 184-189
    • Rehman, A.1    Ismail, S.B.2    Naing, L.3    Roshan, T.M.4    Rahman, A.R.5
  • 135
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint Reduction in Hypertension study (LIFE): A randomised trial against atenolol
    • Dahlöf B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint Reduction in Hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002; 359: 995-1003.
    • (2002) Lancet , vol.359 , pp. 995-1003
    • Dahlöf, B.1    Devereux, R.B.2    Kjeldsen, S.E.3
  • 136
    • 0037174372 scopus 로고    scopus 로고
    • Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: A Losartan Intervention for Endpoint Reduction (LIFE) substudy
    • Kjeldsen SE, Dahlof B, Devereux RB, et al. Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy. JAMA 2002; 288: 1491-1498.
    • (2002) JAMA , vol.288 , pp. 1491-1498
    • Kjeldsen, S.E.1    Dahlof, B.2    Devereux, R.B.3
  • 137
    • 0043164975 scopus 로고    scopus 로고
    • Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol: The Losartan Intervention for Endpoint reduction in Hypertension (LIFE) study
    • Okin PM, Devereux RB, Jern S, et al. Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol: The Losartan Intervention for Endpoint reduction in Hypertension (LIFE) study. Circulation 2003; 108: 684-690.
    • (2003) Circulation , vol.108 , pp. 684-690
    • Okin, P.M.1    Devereux, R.B.2    Jern, S.3
  • 138
    • 4544269713 scopus 로고    scopus 로고
    • Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: The Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial
    • Devereux RB, Dahlöf B, Gerdts E, et al. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial. Circulation 2004; 110: 1456-1462.
    • (2004) Circulation , vol.110 , pp. 1456-1462
    • Devereux, R.B.1    Dahlöf, B.2    Gerdts, E.3
  • 139
    • 0037036971 scopus 로고    scopus 로고
    • Effects of losartan and captopril on mortality and morbidity in highrisk patients after acute myocardial infarction: The OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan
    • Dickstein K, Kjekshus J. Effects of losartan and captopril on mortality and morbidity in highrisk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan. Lancet 2002; 360: 752-760.
    • (2002) Lancet , vol.360 , pp. 752-760
    • Dickstein, K.1    Kjekshus, J.2
  • 140
    • 19944428946 scopus 로고    scopus 로고
    • Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: The Losartan Intervention For Endpoint Reduction in Hypertension study
    • Kizer JR, Dahlöf B, Kjeldsen SE, et al. Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: the Losartan Intervention For Endpoint Reduction in Hypertension study. Hypertension 2005; 45: 46-52.
    • (2005) Hypertension , vol.45 , pp. 46-52
    • Kizer, J.R.1    Dahlöf, B.2    Kjeldsen, S.E.3
  • 141
    • 0030902115 scopus 로고    scopus 로고
    • Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)
    • Pitt B, Segal R, Martinez FA, et al. Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). Lancet 1997; 349: 747-752.
    • (1997) Lancet , vol.349 , pp. 747-752
    • Pitt, B.1    Segal, R.2    Martinez, F.A.3
  • 142
    • 0034048204 scopus 로고    scopus 로고
    • Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: Results of the ELITE ventricular function substudy
    • Konstam MA, Patten RD, Thomas I, et al. Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: results of the ELITE ventricular function substudy. Am Heart J 2000; 139: 1081-1087.
    • (2000) Am Heart J , vol.139 , pp. 1081-1087
    • Konstam, M.A.1    Patten, R.D.2    Thomas, I.3
  • 143
    • 0034612118 scopus 로고    scopus 로고
    • Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: Randomised trial - the Losartan Heart Failure Survival Study ELITE II
    • Pitt B, Poole-Wilson PA, Segal R, et al. Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial - the Losartan Heart Failure Survival Study ELITE II. Lancet 2000; 355: 1582-1587.
    • (2000) Lancet , vol.355 , pp. 1582-1587
    • Pitt, B.1    Poole-Wilson, P.A.2    Segal, R.3
  • 144
    • 20044369896 scopus 로고    scopus 로고
    • Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) study
    • Wachtell K, Lehto M, Gerdts E, et al. Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) study. J Am Coll Cardiol 2005; 45: 712-719.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 712-719
    • Wachtell, K.1    Lehto, M.2    Gerdts, E.3
  • 145
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • RENAAL Study Investigators
    • Brenner BM, Cooper ME, de Zeeuw D, et al. RENAAL Study Investigators. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3
  • 146
    • 10744221480 scopus 로고    scopus 로고
    • Renoprotective effect of losartan in comparison to amlodipine in patients with chronic kidney disease and hypertension - a report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) study
    • Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) Study Investigators
    • Iino Y, Hayashi M, Kawamura T, et al. Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) Study Investigators. Renoprotective effect of losartan in comparison to amlodipine in patients with chronic kidney disease and hypertension - a report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) study. Hypertens Res 2004; 27: 21-30.
    • (2004) Hypertens Res , vol.27 , pp. 21-30
    • Iino, Y.1    Hayashi, M.2    Kawamura, T.3
  • 147
    • 34249897487 scopus 로고    scopus 로고
    • Renoprotection of Optimal Antiproteinuric Doses (ROAD) study: A randomized controlled study of benazepril and losartan in chronic renal insufficiency
    • Hou FF, Xie D, Zhang X, et al. Renoprotection of Optimal Antiproteinuric Doses (ROAD) study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency. J Am Soc Nephrol 2007; 18: 1889-1898.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1889-1898
    • Hou, F.F.1    Xie, D.2    Zhang, X.3
  • 148
    • 45849123477 scopus 로고    scopus 로고
    • Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering
    • Karalliedde J, Smith A, DeAngelis L, et al. Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering. Hypertension 2008; 51: 1617-1623.
    • (2008) Hypertension , vol.51 , pp. 1617-1623
    • Karalliedde, J.1    Smith, A.2    Deangelis, L.3
  • 149
    • 29144470389 scopus 로고    scopus 로고
    • Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial
    • Serebruany VL, Pokov AN, Malinin AI, et al. Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial. Am Heart J 2006; 151: 92-99.
    • (2006) Am Heart J , vol.151 , pp. 92-99
    • Serebruany, V.L.1    Pokov, A.N.2    Malinin, A.I.3
  • 150
    • 25444533272 scopus 로고    scopus 로고
    • Effects of valsartan and perindopril combination therapy on left ventricular hypertrophy and aortic arterial stiffness in patients with essential hypertension
    • Anan F, Takahashi N, Ooie T, et al. Effects of valsartan and perindopril combination therapy on left ventricular hypertrophy and aortic arterial stiffness in patients with essential hypertension. Eur J Clin Pharmacol 2005; 61: 353-359.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 353-359
    • Anan, F.1    Takahashi, N.2    Ooie, T.3
  • 151
    • 0032777331 scopus 로고    scopus 로고
    • Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: Comparison with enalapril
    • Cuocolo A, Storto G, Izzo R, et al. Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: comparison with enalapril. J Hypertens 1999; 17: 1759-1766.
    • (1999) J Hypertens , vol.17 , pp. 1759-1766
    • Cuocolo, A.1    Storto, G.2    Izzo, R.3
  • 152
    • 0032506199 scopus 로고    scopus 로고
    • Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension
    • Thürmann PA, Kenedi P, Schmidt A, Harder S, Rietbrock N. Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension. Circulation 1998; 98: 2037-2042.
    • (1998) Circulation , vol.98 , pp. 2037-2042
    • Thürmann, P.A.1    Kenedi, P.2    Schmidt, A.3    Harder, S.4    Rietbrock, N.5
  • 153
    • 2542475889 scopus 로고    scopus 로고
    • Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy
    • Yasunari K, Maeda K, Watanabe T, Nakamura M, Yoshikawa J, Asada A. Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy. J Am Coll Cardiol 2004; 43: 2116-2123.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 2116-2123
    • Yasunari, K.1    Maeda, K.2    Watanabe, T.3    Nakamura, M.4    Yoshikawa, J.5    Asada, A.6
  • 154
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Valsartan in Acute Myocardial Infarction Trial Investigators
    • Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan in Acute Myocardial Infarction Trial Investigators. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003; 349: 1893-1906.
    • (2003) N Engl J Med , vol.349 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.2    Velazquez, E.J.3
  • 155
    • 21544445252 scopus 로고    scopus 로고
    • Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction
    • Solomon SD, Skali H, Anavekar NS, et al. Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction. Circulation 2005; 111: 3411-3419.
    • (2005) Circulation , vol.111 , pp. 3411-3419
    • Solomon, S.D.1    Skali, H.2    Anavekar, N.S.3
  • 156
    • 65649109725 scopus 로고    scopus 로고
    • Inhibitory effect of valsartan against progression of left ventricular dysfunction after myocardial infarction: T-VENTURE study
    • Suzuki H, Geshi E, Nanjyo S, et al. Inhibitory effect of valsartan against progression of left ventricular dysfunction after myocardial infarction: T-VENTURE study. Circ J 2009; 73: 918-924.
    • (2009) Circ J , vol.73 , pp. 918-924
    • Suzuki, H.1    Geshi, E.2    Nanjyo, S.3
  • 157
    • 34247379373 scopus 로고    scopus 로고
    • Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): A randomised, open-label, blinded endpoint morbidity-mortality study
    • Jikei Heart Study group
    • Mochizuki S, Dahlof B, Shimizu M, et al. Jikei Heart Study group. Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet 2007; 369: 1431-1439.
    • (2007) Lancet , vol.369 , pp. 1431-1439
    • Mochizuki, S.1    Dahlof, B.2    Shimizu, M.3
  • 158
    • 73849084830 scopus 로고    scopus 로고
    • Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study
    • Sawada T, Yamada H, Dahlöf B, Matsubara H. Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study. Eur Heart J 2009; 30: 2461-2469.
    • (2009) Eur Heart J , vol.30 , pp. 2461-2469
    • Sawada, T.1    Yamada, H.2    Dahlöf, B.3    Matsubara, H.4
  • 159
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure
    • Cohn JN, Tognoni G. A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure. N Engl J Med 2001; 345: 1667-1675.
    • (2001) N Engl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 160
    • 0037019554 scopus 로고    scopus 로고
    • Valsartan benefits left ventricular structure and function in heart failure: Val-HeFT echocardiographic study
    • Val-HeFT Heart Failure Trial Investigators
    • Wong M, Staszewsky L, Latini R, et al. Val-HeFT Heart Failure Trial Investigators. Valsartan benefits left ventricular structure and function in heart failure: Val-HeFT echocardiographic study. J Am Coll Cardiol 2002; 40: 970-975.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 970-975
    • Wong, M.1    Staszewsky, L.2    Latini, R.3
  • 161
    • 64749085587 scopus 로고    scopus 로고
    • Valsartan for prevention of recurrent atrial fibrillation
    • GISSI-AF Investigators
    • Disertori M, Latini R, Barlera S, et al. GISSI-AF Investigators. Valsartan for prevention of recurrent atrial fibrillation. N Engl J Med 2009; 360: 1606-1617.
    • (2009) N Engl J Med , vol.360 , pp. 1606-1617
    • Disertori, M.1    Latini, R.2    Barlera, S.3
  • 162
    • 17844369714 scopus 로고    scopus 로고
    • Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: Results from the Valsartan Heart Failure Trial (Val- HeFT)
    • Val-HeFT Investigators
    • Maggioni AP, Latini R, Carson PE, et al. Val-HeFT Investigators. Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart Failure Trial (Val- HeFT). Am Heart J 2005; 149: 548-557.
    • (2005) Am Heart J , vol.149 , pp. 548-557
    • Maggioni, A.P.1    Latini, R.2    Carson, P.E.3
  • 163
    • 0037031270 scopus 로고    scopus 로고
    • Microalbuminuria reduction with valsartan n patients with type 2 diabetes mellitus: A blood pressureindependent effect
    • Viberti G, Wheeldon NM. Microalbuminuria reduction with valsartan n patients with type 2 diabetes mellitus: a blood pressureindependent effect. Circulation 2002; 106: 672-678
    • (2002) Circulation , vol.106 , pp. 672-678
    • Viberti, G.1    Wheeldon, N.M.2
  • 164
    • 34249905442 scopus 로고    scopus 로고
    • Reduction of microalbuminuria in patients with type 2 diabetes: The Shiga Microalbuminuria Reduction Trial (SMART)
    • Uzu T, Sawaguchi M, Maegawa H, Kashiwagi A. Reduction of microalbuminuria in patients with type 2 diabetes: the Shiga Microalbuminuria Reduction Trial (SMART). Diabetes Care 2007; 30: 1581-1583.
    • (2007) Diabetes Care , vol.30 , pp. 1581-1583
    • Uzu, T.1    Sawaguchi, M.2    Maegawa, H.3    Kashiwagi, A.4
  • 165
    • 58149235087 scopus 로고    scopus 로고
    • Valsartan in combination with lisinopril versus the respective high dose monotherapies in hypertensive patients with microalbuminuria: The VALERIA trial
    • Menne J, Farsang C, Deák L, et al. Valsartan in combination with lisinopril versus the respective high dose monotherapies in hypertensive patients with microalbuminuria: the VALERIA trial. J Hypertens 2008; 26: 1860-1867.
    • (2008) J Hypertens , vol.26 , pp. 1860-1867
    • Menne, J.1    Farsang, C.2    Deák, L.3
  • 166
    • 33646483060 scopus 로고    scopus 로고
    • Hong Kong Study Using Valsartan in IgA Nephropathy (HKVIN): A double- blind, randomized, placebo-controlled study
    • HKVIN Study Group
    • Li PK, Leung CB, Chow KM, et al. HKVIN Study Group. Hong Kong Study Using Valsartan in IgA Nephropathy (HKVIN): a double- blind, randomized, placebo-controlled study. Am J Kidney Dis 2006; 47: 751-760.
    • (2006) Am J Kidney Dis , vol.47 , pp. 751-760
    • Li, P.K.1    Leung, C.B.2    Chow, K.M.3
  • 167
    • 14044250200 scopus 로고    scopus 로고
    • Effects of candesartan cilexetil and enalapril on inflammatory markers of atherosclerosis in hypertensive patients with noninsulin diabetes mellitus
    • for the CENTRO (CandEsartaN on aTherosclerotic Risk factors) study investigators
    • Agabiti Rosei E, Rizzoni D, Muiesan ML, et al for the CENTRO (CandEsartaN on aTherosclerotic Risk factors) study investigators. Effects of candesartan cilexetil and enalapril on inflammatory markers of atherosclerosis in hypertensive patients with noninsulin diabetes mellitus. J Hypertens 2005; 23: 435-444.
    • (2005) J Hypertens , vol.23 , pp. 435-444
    • Agabiti, R.E.1    Rizzoni, D.2    Muiesan, M.L.3
  • 168
    • 0036855573 scopus 로고    scopus 로고
    • Comparative effects of candesartan and enalapril on left ventricular hypertrophy in patients with essential hypertension: The candesartan assessment in the treatment of cardiac hypertrophy (CATCH) study
    • CATCH investigators
    • Cuspidi C, Muiesan ML, Valagussa L, et al. CATCH investigators. Comparative effects of candesartan and enalapril on left ventricular hypertrophy in patients with essential hypertension: the candesartan assessment in the treatment of cardiac hypertrophy (CATCH) study. J Hypertens 2002; 20: 2293-2300.
    • (2002) J Hypertens , vol.20 , pp. 2293-2300
    • Cuspidi, C.1    Muiesan, M.L.2    Valagussa, L.3
  • 169
    • 55349147316 scopus 로고    scopus 로고
    • ARB candesartan and CCB amlodipine in hypertensive patients: The CASE-J trial
    • Ogihara T, Fujimoto A, Nakao K, Saruta T. ARB candesartan and CCB amlodipine in hypertensive patients: the CASE-J trial. Expert Rev Cardiovasc Ther 2008; 6: 1195-1201.
    • (2008) Expert Rev Cardiovasc Ther , vol.6 , pp. 1195-1201
    • Ogihara, T.1    Fujimoto, A.2    Nakao, K.3    Saruta, T.4
  • 170
    • 21244435994 scopus 로고    scopus 로고
    • Effects of candesartan on cardiovascular outcomes in Japanese hypertensive patients
    • Suzuki H, Kanno Y. Effects of candesartan on cardiovascular outcomes in Japanese hypertensive patients. Hypertens Res 2005; 28: 307-314.
    • (2005) Hypertens Res , vol.28 , pp. 307-314
    • Suzuki, H.1    Kanno, Y.2
  • 171
    • 0037534905 scopus 로고    scopus 로고
    • The Study on Cognition and Prognosis in the Elderly (SCOPE): Principal results of a randomized double-blind intervention trial
    • SCOPE Study Group
    • Lithell H, Hansson L, Skoog I, et al. SCOPE Study Group. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 2003; 21: 875-886.
    • (2003) J Hypertens , vol.21 , pp. 875-886
    • Lithell, H.1    Hansson, L.2    Skoog, I.3
  • 172
    • 4444236607 scopus 로고    scopus 로고
    • Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: The Study on Cognition and Prognosis in the Elderly (SCOPE)
    • Study on Cognition and Prognosis in the Elderly study group
    • Papademetriou V, Farsang C, Elmfeldt D, et al. Study on Cognition and Prognosis in the Elderly study group. Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE). J Am Coll Cardiol 2004; 44: 1175-1180.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1175-1180
    • Papademetriou, V.1    Farsang, C.2    Elmfeldt, D.3
  • 173
    • 0033533456 scopus 로고    scopus 로고
    • Comparison of candesartan, enalapril, and their combination in congestive heart failure: Randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators
    • McKelvie RS, Yusuf S, Pericak D, et al. Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators. Circulation 1999; 100: 1056-1064.
    • (1999) Circulation , vol.100 , pp. 1056-1064
    • McKelvie, R.S.1    Yusuf, S.2    Pericak, D.3
  • 174
    • 0042410539 scopus 로고    scopus 로고
    • Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARMOverall programme
    • CHARM Investigators and Committees
    • Pfeffer MA, Swedberg K, Granger CB, et al. CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARMOverall programme. Lancet 2003; 362: 759-766.
    • (2003) Lancet , vol.362 , pp. 759-766
    • Pfeffer, M.A.1    Swedberg, K.2    Granger, C.B.3
  • 175
    • 20844444592 scopus 로고    scopus 로고
    • Effect of candesartan on cause-specific mortality in heart failure patients: The Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM) program
    • Solomon SD, Wang D, Finn P, et al. Effect of candesartan on cause-specific mortality in heart failure patients: the Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM) program. Circulation 2004; 110: 2180-2183.
    • (2004) Circulation , vol.110 , pp. 2180-2183
    • Solomon, S.D.1    Wang, D.2    Finn, P.3
  • 176
    • 7544246246 scopus 로고    scopus 로고
    • Effect of candesartan on New York Heart Association functional class. Results of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) programme
    • O'Meara E, Solomon S, McMurray J, et al. Effect of candesartan on New York Heart Association functional class. Results of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) programme. Eur Heart J 2004; 25: 1920-1926.
    • (2004) Eur Heart J , vol.25 , pp. 1920-1926
    • O'Meara, E.1    Solomon, S.2    McMurray, J.3
  • 177
    • 7544249402 scopus 로고    scopus 로고
    • Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM) Investigators and Committees. Mortality and morbidity reduction with candesartan in patients with chronic heart failure and left ventricular systolic dysfunction: Results of the CHARM low-left ventricular ejection fraction trials
    • Young JB, Dunlap ME, Pfeffer MA, et al. Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM) Investigators and Committees. Mortality and morbidity reduction with candesartan in patients with chronic heart failure and left ventricular systolic dysfunction: results of the CHARM low-left ventricular ejection fraction trials. Circulation 2004; 110: 2618-2626.
    • (2004) Circulation , vol.110 , pp. 2618-2626
    • Young, J.B.1    Dunlap, M.E.2    Pfeffer, M.A.3
  • 178
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • CHARM Investigators and Committees
    • McMurray JJ, Ostergren J, Swedberg K, et al. CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003; 362: 767-771.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3
  • 179
    • 0041909380 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARMAlternative trial
    • CHARM Investigators and Committees
    • Granger CB, McMurray JJ, Yusuf S, et al. CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARMAlternative trial. Lancet 2003; 362: 772-776.
    • (2003) Lancet , vol.362 , pp. 772-776
    • Granger, C.B.1    McMurray, J.J.2    Yusuf, S.3
  • 180
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM-Preserved trial
    • CHARM Investigators and Committees
    • Yusuf S, Pfeffer MA, Swedberg K, et al. CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial. Lancet 2003; 362: 777-781.
    • (2003) Lancet , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3
  • 181
    • 34347349119 scopus 로고    scopus 로고
    • Candesartan in the prevention of relapsing atrial fibrillation
    • Tveit A, Grundvold I, Olufsen M, et al. Candesartan in the prevention of relapsing atrial fibrillation. Int J Cardiol 2007; 120: 85-91.
    • (2007) Int J Cardiol , vol.120 , pp. 85-91
    • Tveit, A.1    Grundvold, I.2    Olufsen, M.3
  • 182
    • 67649659279 scopus 로고    scopus 로고
    • Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: Three randomized trials
    • Bilous R, Chaturvedi N, Sjølie AK, et al. Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials. Ann Intern Med 2009; 151: 11-14.
    • (2009) Ann Intern Med , vol.151 , pp. 11-14
    • Bilous, R.1    Chaturvedi, N.2    Sjølie, A.K.3
  • 183
    • 34247156618 scopus 로고    scopus 로고
    • Irbesartan reduces common carotid artery intimamedia thickness in hypertensive patients when compared with atenolol: The Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) study
    • Mörtsell D, Malmqvist K, Held C, Kahan T. Irbesartan reduces common carotid artery intimamedia thickness in hypertensive patients when compared with atenolol: the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) study. J Intern Med 2007; 261: 472-479.
    • (2007) J Intern Med , vol.261 , pp. 472-479
    • Mörtsell, D.1    Malmqvist, K.2    Held, C.3    Kahan, T.4
  • 184
    • 33747159626 scopus 로고    scopus 로고
    • Endothelial Protection, AT1 Blockade and Cholesterol-Dependent Oxidative Stress: The EPAS trial
    • Morawietz H, Erbs S, Holtz J, et al. Endothelial Protection, AT1 Blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial. Circulation 2006; 114(1 suppl): I296-I301.
    • (2006) Circulation , vol.114 , Issue.1 SUPPL.
    • Morawietz, H.1    Erbs, S.2    Holtz, J.3
  • 185
    • 12844260091 scopus 로고    scopus 로고
    • Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: Results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study
    • Sola S, Mir MQ, Cheema FA, et al. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study. Circulation 2005; 111: 343-348.
    • (2005) Circulation , vol.111 , pp. 343-348
    • Sola, S.1    Mir, M.Q.2    Cheema, F.A.3
  • 186
    • 0035007259 scopus 로고    scopus 로고
    • Regression of left ventricular hypertrophy in human hypertension with irbesartan
    • Malmqvist K, Kahan T, Edner M, et al. Regression of left ventricular hypertrophy in human hypertension with irbesartan. J Hypertens 2001; 19: 1167-1176.
    • (2001) J Hypertens , vol.19 , pp. 1167-1176
    • Malmqvist, K.1    Kahan, T.2    Edner, M.3
  • 187
    • 0344586161 scopus 로고    scopus 로고
    • Long-term effects of irbesartan and atenolol on the renin-angiotensinaldosterone system in human primary hypertension: The Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)
    • Malmqvist K, Öhman KP, Lind L, Nyström F, Kahan T. Long-term effects of irbesartan and atenolol on the renin-angiotensinaldosterone system in human primary hypertension: the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA). J Cardiovasc Pharmacol 2003; 42: 719-726.
    • (2003) J Cardiovasc Pharmacol , vol.42 , pp. 719-726
    • Malmqvist, K.1    Öhman, K.P.2    Lind, L.3    Nyström, F.4    Kahan, T.5
  • 188
    • 3042628521 scopus 로고    scopus 로고
    • Effect of irbesartan versus atenolol on left ventricular mass and voltage: Results of the CardioVascular Irbesartan Project
    • Schneider MP, Klingbeil AU, Delles C, et al. Effect of irbesartan versus atenolol on left ventricular mass and voltage: results of the CardioVascular Irbesartan Project. Hypertension 2004; 44: 61-66.
    • (2004) Hypertension , vol.44 , pp. 61-66
    • Schneider, M.P.1    Klingbeil, A.U.2    Delles, C.3
  • 189
    • 57349142933 scopus 로고    scopus 로고
    • Irbesartan in patients with heart failure and preserved ejection fraction
    • I-PRESERVE Investigators
    • Massie BM, Carson PE, McMurray JJ, et al. I-PRESERVE Investigators. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med 2008; 359: 2456-2467.
    • (2008) N Engl J Med , vol.359 , pp. 2456-2467
    • Massie, B.M.1    Carson, P.E.2    McMurray, J.J.3
  • 190
    • 58749088068 scopus 로고    scopus 로고
    • Comparison of the effects of quinapril and irbesartan on P-wave dispersion in hypertensive patients
    • Guntekin U, Gunes Y, Tuncer M, Simsek H, Gunes A. Comparison of the effects of quinapril and irbesartan on P-wave dispersion in hypertensive patients. Adv Ther 2008; 25: 775-786.
    • (2008) Adv Ther , vol.25 , pp. 775-786
    • Guntekin, U.1    Gunes, Y.2    Tuncer, M.3    Simsek, H.4    Gunes, A.5
  • 191
    • 0037118662 scopus 로고    scopus 로고
    • Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: A prospective and randomized study
    • Madrid AH, Bueno MG, Rebollo JM, et al. Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: a prospective and randomized study. Circulation 2002; 106: 331-336.
    • (2002) Circulation , vol.106 , pp. 331-336
    • Madrid, A.H.1    Bueno, M.G.2    Rebollo, J.M.3
  • 192
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 193
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group
    • Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P. Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-878.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Bröchner-Mortensen, J.3    Gomis, R.4    Andersen, S.5    Arner, P.6
  • 194
    • 34648820103 scopus 로고    scopus 로고
    • Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: Results of the IMPROVE trial
    • Bakris GL, Ruilope L, Locatelli F, et al. Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial. Kidney Int 2007; 72: 879-8785.
    • (2007) Kidney Int , vol.72 , pp. 879-8785
    • Bakris, G.L.1    Ruilope, L.2    Locatelli, F.3
  • 196
    • 67549135784 scopus 로고    scopus 로고
    • The effect of telmisartan on endothelial function and arterial stiffness in patients with essential hypertension
    • Jung AD, Kim W, Park SH, et al. The effect of telmisartan on endothelial function and arterial stiffness in patients with essential hypertension. Korean Circ J 2009; 39: 180-184.
    • (2009) Korean Circ J , vol.39 , pp. 180-184
    • Jung, A.D.1    Kim, W.2    Park, S.H.3
  • 197
    • 70349972814 scopus 로고    scopus 로고
    • Effects of telmisartan, ramipril, and their combination on left ventricular hypertrophy in individuals at high vascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial and the Telmisartan Randomized Assessment Study in ACE Intolerant Subjects With Cardiovascular Disease
    • for the ONTARGET/ TRANSCEND Investigators
    • Verdecchia P, Sleight P, Mancia G, et al. for the ONTARGET/ TRANSCEND Investigators. Effects of telmisartan, ramipril, and their combination on left ventricular hypertrophy in individuals at high vascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial and the Telmisartan Randomized Assessment Study in ACE Intolerant Subjects With Cardiovascular Disease. Circulation 2009; 120: 1380-1389.
    • (2009) Circulation , vol.120 , pp. 1380-1389
    • Verdecchia, P.1    Sleight, P.2    Mancia, G.3
  • 198
    • 53049109468 scopus 로고    scopus 로고
    • Effects of the angiotensinreceptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial
    • for the Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators
    • Yusuf S, Teo K, Anderson C, et al. for the Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Effects of the angiotensinreceptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Lancet 2008; 372: 1174-1183.
    • (2008) Lancet , vol.372 , pp. 1174-1183
    • Yusuf, S.1    Teo, K.2    Anderson, C.3
  • 199
    • 52249116778 scopus 로고    scopus 로고
    • Telmisartan to prevent recurrent stroke and cardiovascular events
    • PROFESS Study Group
    • Yusuf S, Diener HC, Sacco RL, et al. PROFESS Study Group. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med 2008; 359: 1225-1237.
    • (2008) N Engl J Med , vol.359 , pp. 1225-1237
    • Yusuf, S.1    Diener, H.C.2    Sacco, R.L.3
  • 200
    • 0035131633 scopus 로고    scopus 로고
    • Effects of the replacement of the angiotensin converting enzyme inhibitor enalapril by the angiotensin II receptor blocker telmisartan in patients with congestive heart failure. The Replacement of Angiotensin Converting Enzyme Inhibition (REPLACE) investigators
    • Dunselman PH. Effects of the replacement of the angiotensin converting enzyme inhibitor enalapril by the angiotensin II receptor blocker telmisartan in patients with congestive heart failure. The Replacement of Angiotensin Converting Enzyme Inhibition (REPLACE) investigators. Int J Cardiol 2001; 77: 131-138.
    • (2001) Int J Cardiol , vol.77 , pp. 131-138
    • Dunselman, P.H.1
  • 201
    • 20444393396 scopus 로고    scopus 로고
    • The comparative effects of telmisartan and ramipril on P-wave dispersion in hypertensive patients: A randomized clinical study
    • Celik T, Iyisoy A, Kursaklioglu H, et al. The comparative effects of telmisartan and ramipril on P-wave dispersion in hypertensive patients: a randomized clinical study. Clin Cardiol 2005; 28: 298-302.
    • (2005) Clin Cardiol , vol.28 , pp. 298-302
    • Celik, T.1    Iyisoy, A.2    Kursaklioglu, H.3
  • 202
    • 34249899918 scopus 로고    scopus 로고
    • Prevention of transition from incipient to overt nephropathy with telmisartan in patients with type 2 diabetes
    • for the INNOVATION Study Group
    • Makino H, Haneda M, Babazono T, et al. for the INNOVATION Study Group. Prevention of transition from incipient to overt nephropathy with telmisartan in patients with type 2 diabetes. Diabetes Care 2007; 30: 1577-1578.
    • (2007) Diabetes Care , vol.30 , pp. 1577-1578
    • Makino, H.1    Haneda, M.2    Babazono, T.3
  • 203
    • 67650070753 scopus 로고    scopus 로고
    • TRANSCEND (Telmisartan Randomised Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease) Investigators. Effect of telmisartan on renal outcomes: A randomized trial
    • Mann JF, Schmieder RE, Dyal L, et al. TRANSCEND (Telmisartan Randomised Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease) Investigators. Effect of telmisartan on renal outcomes: a randomized trial. Ann Intern Med 2009; 151: 1-10
    • (2009) Ann Intern Med , vol.151 , pp. 1-10
    • Mann, J.F.1    Schmieder, R.E.2    Dyal, L.3
  • 204
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • for the ONTARGET Investigators
    • Mann JF, Schmieder RE, McQueen M, et al. for the ONTARGET Investigators. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial. Lancet 2008; 372: 547-553.
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3
  • 205
    • 33645470403 scopus 로고    scopus 로고
    • Preventing renal complications in type 2 diabetes: Results of the diabetics exposed to telmisartan and enalapril trial
    • Barnett A. Preventing renal complications in type 2 diabetes: results of the diabetics exposed to telmisartan and enalapril trial. J Am Soc Nephrol 2006; 17: S132-S135.
    • (2006) J Am Soc Nephrol , vol.17
    • Barnett, A.1
  • 206
    • 6344252861 scopus 로고    scopus 로고
    • A double blind randomized trial to compare the effects of eprosartan and enalapril on blood pressure, platelets, and endothelium function in patients with essential hypertension
    • Leu HB, Charng MJ, Ding PY. A double blind randomized trial to compare the effects of eprosartan and enalapril on blood pressure, platelets, and endothelium function in patients with essential hypertension. Jpn Heart J 2004; 45: 623-635.
    • (2004) Jpn Heart J , vol.45 , pp. 623-635
    • Leu, H.B.1    Charng, M.J.2    Ding, P.Y.3
  • 207
    • 4844231461 scopus 로고    scopus 로고
    • Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation
    • for the EUropean Trial on Olmesartan and Pravastatin in Inflammation and Atherosclerosis (EUTOPIA) Investigators, 2004 Aug 31
    • Fliser D, Buchholz K, Haller H; for the EUropean Trial on Olmesartan and Pravastatin in Inflammation and Atherosclerosis (EUTOPIA) Investigators. Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. Circulation 2004 Aug 31; 110(9): 1103-1107.
    • Circulation , vol.110 , Issue.9 , pp. 1103-1107
    • Fliser, D.1    Buchholz, K.2    Haller, H.3
  • 208
    • 0032960157 scopus 로고    scopus 로고
    • Effect of longterm eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group
    • Diamond JA, Gharavi A, Roychoudhury D, et al. Effect of longterm eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group. Curr Med Res Opin 1999; 15: 1-8.
    • (1999) Curr Med Res Opin , vol.15 , pp. 1-8
    • Diamond, J.A.1    Gharavi, A.2    Roychoudhury, D.3
  • 209
    • 67651122005 scopus 로고    scopus 로고
    • Comparison of olmesartan medoxomil versus amlodipine besylate on regression of ventricular and vascular hypertrophy
    • Rosendorff C, Dubiel R, Xu J, Chavanu KJ. Comparison of olmesartan medoxomil versus amlodipine besylate on regression of ventricular and vascular hypertrophy. Am J Cardiol 2009; 104: 359-365.
    • (2009) Am J Cardiol , vol.104 , pp. 359-365
    • Rosendorff, C.1    Dubiel, R.2    Xu, J.3    Chavanu, K.J.4
  • 210
    • 20444427156 scopus 로고    scopus 로고
    • Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: Principal results of a prospective randomized controlled study (MOSES)
    • Schrader J, Luders S, Kulschewski A, et al. Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 2005; 36: 1218-1226.
    • (2005) Stroke , vol.36 , pp. 1218-1226
    • Schrader, J.1    Luders, S.2    Kulschewski, A.3
  • 211
    • 0034744446 scopus 로고    scopus 로고
    • ADEPT: Addition of the AT1 receptor antagonist eprosartan to ACE inhibitor therapy in chronic heart failure trial: Hemodynamic and neurohormonal effects
    • Murdoch DR, McDonagh TA, Farmer R, Morton JJ, McMurray JJ, Dargie HJ. ADEPT: addition of the AT1 receptor antagonist eprosartan to ACE inhibitor therapy in chronic heart failure trial: hemodynamic and neurohormonal effects. Am Heart J 2001; 141: 800-807
    • (2001) Am Heart J , vol.141 , pp. 800-807
    • Murdoch, D.R.1    McDonagh, T.A.2    Farmer, R.3    Morton, J.J.4    McMurray, J.J.5    Dargie, H.J.6
  • 212
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • for the ROADMAP Trial Investigators
    • Haller H, Ito S, Izzo JL Jr, Januszewicz A, Katayama S, Menne J. for the ROADMAP Trial Investigators. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364(10): 907-917.
    • (2011) N Engl J Med , vol.364 , Issue.10 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo Jr., J.L.3    Januszewicz, A.4    Katayama, S.5    Menne, J.6
  • 213
    • 36248994286 scopus 로고    scopus 로고
    • Direct renin inhibition: Focus on aliskiren
    • Pool JL. Direct renin inhibition: focus on aliskiren. J Manag Care Pharm 2007; 13(8)(suppl b): S21-S33.
    • (2007) J Manag Care Pharm , vol.13 , Issue.SUPPL. b
    • Pool, J.L.1
  • 214
    • 22544434079 scopus 로고    scopus 로고
    • Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension
    • Agabiti Rosei E, Morelli P, Rizzoni D. Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension. Blood Press 2005; 1: 14-22.
    • (2005) Blood Press , vol.1 , pp. 14-22
    • Agabiti, R.E.1    Morelli, P.2    Rizzoni, D.3
  • 215
    • 0025262272 scopus 로고
    • Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit
    • Chobanian AV, Haudenschild CC, Nickerson C, Drago R. Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension 1990; 15: 327-331.
    • (1990) Hypertension , vol.15 , pp. 327-331
    • Chobanian, A.V.1    Haudenschild, C.C.2    Nickerson, C.3    Drago, R.4
  • 217
    • 77953025722 scopus 로고    scopus 로고
    • Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB
    • 2010 May 12
    • Miguel-Carrasco JL, Zambrano S, Blanca AJ, Mate A, Vázquez CM. Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB. J Inflamm (Lond) 2010 May 12; 7: 21.
    • J Inflamm (Lond) , vol.7 , pp. 21
    • Miguel-Carrasco, J.L.1    Zambrano, S.2    Blanca, A.J.3    Mate, A.4    Vázquez, C.M.5
  • 218
    • 0034146466 scopus 로고    scopus 로고
    • Differential effects of short-term ace- and AT1-receptor inhibition on postischemic injury and leukocyte adherence in vivo and in vitro
    • Guba M, Steinbauer M, Büchner M, et al. Differential effects of short-term ace- and AT1-receptor inhibition on postischemic injury and leukocyte adherence in vivo and in vitro. Shock 2000; 13(3):190-196.
    • (2000) Shock , vol.13 , Issue.3 , pp. 190-196
    • Guba, M.1    Steinbauer, M.2    Büchner, M.3
  • 219
    • 9444280103 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study
    • Mancini GB, Henry GC, Macaya C, et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation 1996; 94(3): 258-265.
    • (1996) Circulation , vol.94 , Issue.3 , pp. 258-265
    • Mancini, G.B.1    Henry, G.C.2    Macaya, C.3
  • 220
    • 0035852775 scopus 로고    scopus 로고
    • Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: Role of superoxide dismutase
    • 2001 Feb 13
    • Hornig B, Landmesser U, Kohler C, et al. Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: role of superoxide dismutase. Circulation 2001 Feb 13; 103(6): 799-805.
    • Circulation , vol.103 , Issue.6 , pp. 799-805
    • Hornig, B.1    Landmesser, U.2    Kohler, C.3
  • 221
    • 34249869003 scopus 로고    scopus 로고
    • Impact of telmisartan versus ramipril on renal endothelial function in patients with hypertension and type 2 diabetes
    • Schmieder RE, Delles C, Mimran A, Fauvel JP, Ruilope LM. Impact of telmisartan versus ramipril on renal endothelial function in patients with hypertension and type 2 diabetes. Diabetes Care 2007; 30(6): 1351-1356.
    • (2007) Diabetes Care , vol.30 , Issue.6 , pp. 1351-1356
    • Schmieder, R.E.1    Delles, C.2    Mimran, A.3    Fauvel, J.P.4    Ruilope, L.M.5
  • 222
    • 0033966627 scopus 로고    scopus 로고
    • Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
    • Anderson TJ, Elstein E, Haber H, Charbonneau F. Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study). J Am Coll Cardiol 2000; 35(1): 60-66.
    • (2000) J Am Coll Cardiol , vol.35 , Issue.1 , pp. 60-66
    • Anderson, T.J.1    Elstein, E.2    Haber, H.3    Charbonneau, F.4
  • 223
    • 0031923033 scopus 로고    scopus 로고
    • Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities
    • Ferri C, Desideri G, Baldoncini R, et al. Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities. Diabetes 1998; 47(4): 660-667.
    • (1998) Diabetes , vol.47 , Issue.4 , pp. 660-667
    • Ferri, C.1    Desideri, G.2    Baldoncini, R.3
  • 224
    • 0033034629 scopus 로고    scopus 로고
    • Fosinopril decreases levels of soluble vascular cell adhesion molecule-1 in borderline hypertensive type II diabetic patients with microalbuminuria
    • Gasic S, Wagner OF, Fasching P, et al. Fosinopril decreases levels of soluble vascular cell adhesion molecule-1 in borderline hypertensive type II diabetic patients with microalbuminuria. Am J Hypertens. 1999; 12(2 Pt 1): 217-222.
    • (1999) Am J Hypertens , vol.12 , Issue.2 Pt 1 , pp. 217-222
    • Gasic, S.1    Wagner, O.F.2    Fasching, P.3
  • 225
    • 0033911305 scopus 로고    scopus 로고
    • Angiotensin II blockade is associated with decreased plasma leukocyte adhesion molecule levels in diabetic nephropathy
    • Andersen S, Schalkwijk CG, Stehouwer CD, Parving HH. Angiotensin II blockade is associated with decreased plasma leukocyte adhesion molecule levels in diabetic nephropathy. Diabetes Care 2000; 23(7): 1031-1032.
    • (2000) Diabetes Care , vol.23 , Issue.7 , pp. 1031-1032
    • Andersen, S.1    Schalkwijk, C.G.2    Stehouwer, C.D.3    Parving, H.H.4
  • 226
    • 0036348676 scopus 로고    scopus 로고
    • Effects of enalapril and losartan on circulating adhesion molecules and monocytes chemotactic protein-1
    • Jilma B, Li-Saw-Hee FL, Wagner OF, Beevers DG, Lip GY. Effects of enalapril and losartan on circulating adhesion molecules and monocytes chemotactic protein-1. Clin Sci (Lond) 2002; 103: 131-136.
    • (2002) Clin Sci (Lond) , vol.103 , pp. 131-136
    • Jilma, B.1    Li-Saw-Hee, F.L.2    Wagner, O.F.3    Beevers, D.G.4    Lip, G.Y.5
  • 227
    • 0036794826 scopus 로고    scopus 로고
    • Zofenopril inhibits the expression of adhesion molecules on endothelial cells by reducing reactive oxygen species
    • 2002 Oct
    • Cominacini L, Pasini A, Garbin U, et al. Zofenopril inhibits the expression of adhesion molecules on endothelial cells by reducing reactive oxygen species. Am J Hypertens. 2002 Oct; 15(10 Pt 1): 891-895.
    • Am J Hypertens , vol.15 , Issue.10 Pt 1 , pp. 891-895
    • Cominacini, L.1    Pasini, A.2    Garbin, U.3
  • 228
    • 0036711320 scopus 로고    scopus 로고
    • Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure
    • IMPRESS Investigators
    • Sheth T, Parker T, Block A, et al. IMPRESS Investigators. Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure. Am J Cardiol 2002; 90(5): 496-500.
    • (2002) Am J Cardiol , vol.90 , Issue.5 , pp. 496-500
    • Sheth, T.1    Parker, T.2    Block, A.3
  • 229
    • 0036176442 scopus 로고    scopus 로고
    • Impact of angiotensin converting enzyme inhibition on post-coronary artery bypass interleukin 6 release
    • Brull DJ, Sanders J, Rumley A, Lowe GD, Humphries SE, Montgomery HE. Impact of angiotensin converting enzyme inhibition on post-coronary artery bypass interleukin 6 release. Heart. 2002; 87(3): 252-255.
    • (2002) Heart , vol.87 , Issue.3 , pp. 252-255
    • Brull, D.J.1    Sanders, J.2    Rumley, A.3    Lowe, G.D.4    Humphries, S.E.5    Montgomery, H.E.6
  • 230
    • 4444268576 scopus 로고    scopus 로고
    • Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene
    • Trevelyan J, Brull DJ, Needham EW, Montgomery HE, Morris A, Mattu RK. Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene. Am J Cardiol 2004; 94(5): 564-569.
    • (2004) Am J Cardiol , vol.94 , Issue.5 , pp. 564-569
    • Trevelyan, J.1    Brull, D.J.2    Needham, E.W.3    Montgomery, H.E.4    Morris, A.5    Mattu, R.K.6
  • 231
    • 33747250064 scopus 로고    scopus 로고
    • Correlation of flow mediated dilation with inflammatory markers in patients with impaired cardiac function. Beneficial effects of inhibition of ACE
    • Kovacs I, Toth J, Tarjan J, Koller A. Correlation of flow mediated dilation with inflammatory markers in patients with impaired cardiac function. Beneficial effects of inhibition of ACE. Eur J Heart Fail 2006; 8(5): 451-459.
    • (2006) Eur J Heart Fail , vol.8 , Issue.5 , pp. 451-459
    • Kovacs, I.1    Toth, J.2    Tarjan, J.3    Koller, A.4
  • 232
    • 18844445944 scopus 로고    scopus 로고
    • Influence of the angiotensin converting enzyme inhibitor ramipril on high-sensitivity C-reactive protein (hs-CRP) in patients with documented atherosclerosis
    • Mitrovic V, Klein HH, Krekel N, et al. Influence of the angiotensin converting enzyme inhibitor ramipril on high-sensitivity C-reactive protein (hs-CRP) in patients with documented atherosclerosis. Z Kardiol 2005; 94: 336-342.
    • (2005) Z Kardiol , vol.94 , pp. 336-342
    • Mitrovic, V.1    Klein, H.H.2    Krekel, N.3
  • 233
    • 0345599227 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor use is associated with reduced plasma concentration of C-reactive protein in patients with first-ever ischemic stroke
    • Di Napoli M, Papa F. Angiotensin-converting enzyme inhibitor use is associated with reduced plasma concentration of C-reactive protein in patients with first-ever ischemic stroke. Stroke 2003; 34: 2922-2929.
    • (2003) Stroke , vol.34 , pp. 2922-2929
    • Di Napoli, M.1    Papa, F.2
  • 234
    • 3242720779 scopus 로고    scopus 로고
    • Comparative effects of AT1- antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease
    • Schieffer B, Bunte C, Witte J, et al. Comparative effects of AT1- antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease. J Am Coll Cardiol 2004; 44: 362-368.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 362-368
    • Schieffer, B.1    Bunte, C.2    Witte, J.3
  • 235
    • 27744547021 scopus 로고    scopus 로고
    • Effects of Angiotensin-converting enzyme inhibition and statin treatment on inflammatory markers and endothelial functions in patients with longterm rheumatoid arthritis
    • Tikiz C, Utuk O, Pirildar T, et al. Effects of Angiotensin-converting enzyme inhibition and statin treatment on inflammatory markers and endothelial functions in patients with longterm rheumatoid arthritis. J Rheumatol 2005; 32(11): 2095-20101.
    • (2005) J Rheumatol , vol.32 , Issue.11 , pp. 2095-20101
    • Tikiz, C.1    Utuk, O.2    Pirildar, T.3
  • 236
    • 19644400972 scopus 로고    scopus 로고
    • Angiotensin-converting-enzyme inhibition in stable coronary artery disease
    • PEACE Trial Investigators
    • Braunwald E, Domanski MJ, Fowler SE, et al. PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351: 2058-2068.
    • (2004) N Engl J Med , vol.351 , pp. 2058-2068
    • Braunwald, E.1    Domanski, M.J.2    Fowler, S.E.3
  • 237
    • 3042797776 scopus 로고    scopus 로고
    • Exploring the effects of ACE inhibitor tissue penetration on vascular inflammation following acute myocardial infarction
    • Tsikouris JP, Suarez JA, Simoni JS, Ziska M, Meyerrose GE. Exploring the effects of ACE inhibitor tissue penetration on vascular inflammation following acute myocardial infarction. Coron Artery Dis 2004; 15(4): 211-217.
    • (2004) Coron Artery Dis , vol.15 , Issue.4 , pp. 211-217
    • Tsikouris, J.P.1    Suarez, J.A.2    Simoni, J.S.3    Ziska, M.4    Meyerrose, G.E.5
  • 238
    • 67849092315 scopus 로고    scopus 로고
    • Effect of angiotensin- converting enzyme inhibition on C-reactive protein levels: The ramipril C-reactive pRotein randomized evaluation (4R) trial results
    • for the ramipril C-reactive pRotein randomized evaluation (4R) trial investigators
    • Verma S, Lonn EM, Nanji A, et al for the ramipril C-reactive pRotein randomized evaluation (4R) trial investigators. Effect of angiotensin- converting enzyme inhibition on C-reactive protein levels: the ramipril C-reactive pRotein randomized evaluation (4R) trial results. Can J Cardiol 2009; 25(7): e236-e240.
    • (2009) Can J Cardiol , vol.25 , Issue.7
    • Verma, S.1    Lonn, E.M.2    Nanji, A.3
  • 239
    • 20044375205 scopus 로고    scopus 로고
    • Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes
    • Koh KK, Quon MJ, Han SH, et al. Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes. Hypertension 2005; 45(6): 1088-1093.
    • (2005) Hypertension , vol.45 , Issue.6 , pp. 1088-1093
    • Koh, K.K.1    Quon, M.J.2    Han, S.H.3
  • 240
    • 38949118304 scopus 로고    scopus 로고
    • Effects of ramipril on endothelial function and the expression of proinflammatory cytokines and adhesion molecules in young normotensive subjects with successfully repaired coarctation of aorta: A randomized cross-over study
    • Brili S, Tousoulis D, Antoniades C, et al. Effects of ramipril on endothelial function and the expression of proinflammatory cytokines and adhesion molecules in young normotensive subjects with successfully repaired coarctation of aorta: a randomized cross-over study. J Am Coll Cardiol 2008; 51(7): 742-749.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.7 , pp. 742-749
    • Brili, S.1    Tousoulis, D.2    Antoniades, C.3
  • 241
    • 38149104528 scopus 로고    scopus 로고
    • Effects of irbesartan and perindopril on forearm reactive hyperemia and inflammatory process, in normotensive patients with coronary artery disease
    • 2008 Feb 20
    • Tousoulis D, Kourtellaris P, Antoniades C, et al. Effects of irbesartan and perindopril on forearm reactive hyperemia and inflammatory process, in normotensive patients with coronary artery disease. Int J Cardiol 2008 Feb 20; 124(1): 127-129.
    • Int J Cardiol , vol.124 , Issue.1 , pp. 127-129
    • Tousoulis, D.1    Kourtellaris, P.2    Antoniades, C.3
  • 242
    • 52049119316 scopus 로고    scopus 로고
    • Pleiotropic effects of angiotensin-converting enzyme inhibitors in normotensive patients with coronary artery disease
    • Krysiak R, Okopień B. Pleiotropic effects of angiotensin-converting enzyme inhibitors in normotensive patients with coronary artery disease. Pharmacol Rep. 2008; 60(4): 514-523.
    • (2008) Pharmacol Rep , vol.60 , Issue.4 , pp. 514-523
    • Krysiak, R.1    Okopień, B.2
  • 243
    • 58649107380 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme inhibition and novel cardiovascular risk biomarkers: Results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    • Cesari M, Kritchevsky SB, Atkinson HH, et al. Angiotensinconverting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. Am Heart J 2009; 157: 334.e1-e8.
    • (2009) Am Heart J , vol.157 , Issue.334
    • Cesari, M.1    Kritchevsky, S.B.2    Atkinson, H.H.3
  • 244
    • 0036111215 scopus 로고    scopus 로고
    • Anti-atherosclerotic efficacy of olmesartan
    • Miyazaki M, Takai S. Anti-atherosclerotic efficacy of olmesartan. J Hum Hypertens 2002; 16(suppl): S7-S12.
    • (2002) J Hum Hypertens , vol.16 , Issue.SUPPL.
    • Miyazaki, M.1    Takai, S.2
  • 245
    • 0034603775 scopus 로고    scopus 로고
    • Inhibition of early atherogenesis by losartan in monkeys with dietinduced hypercholesterolemia
    • Strawn WB, Chappell MC, Dean RH, Kivlighn S, Ferrario CM. Inhibition of early atherogenesis by losartan in monkeys with dietinduced hypercholesterolemia. Circulation 2000; 101: 1586-1593.
    • (2000) Circulation , vol.101 , pp. 1586-1593
    • Strawn, W.B.1    Chappell, M.C.2    Dean, R.H.3    Kivlighn, S.4    Ferrario, C.M.5
  • 246
    • 0038476580 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1
    • Proudfoot JM, Croft KD, Puddey IB, Beilin LJ. Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1. J Pharmacol Exp Ther 2003; 305: 846-853.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 846-853
    • Proudfoot, J.M.1    Croft, K.D.2    Puddey, I.B.3    Beilin, L.J.4
  • 247
    • 0141564521 scopus 로고    scopus 로고
    • Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: Evidence of an antiinflammatory action
    • 2003 Sep
    • Dandona P, Kumar V, Aljada A, et al. Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action. J Clin Endocrinol Metab 2003 Sep; 88(9): 4496-4501.
    • J Clin Endocrinol Metab , vol.88 , Issue.9 , pp. 4496-4501
    • Dandona, P.1    Kumar, V.2    Aljada, A.3
  • 248
    • 33847115692 scopus 로고    scopus 로고
    • Antihypertensive medications and C-reactive protein in the multi-ethnic study of atherosclerosis
    • Palmas W, Ma S, Psaty B, Goff DC Jr, Darwin C, Barr RG. Antihypertensive medications and C-reactive protein in the multi-ethnic study of atherosclerosis. Am J Hypertens 2007; 20(3): 233-241.
    • (2007) Am J Hypertens , vol.20 , Issue.3 , pp. 233-241
    • Palmas, W.1    Ma, S.2    Psaty, B.3    Goff Jr., D.C.4    Darwin, C.5    Barr, R.G.6
  • 249
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz RM. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation 2000; 101(14): 1653-1659.
    • (2000) Circulation , vol.101 , Issue.14 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.M.4
  • 250
  • 251
    • 1542514995 scopus 로고    scopus 로고
    • Effects of AT1 receptor antagonist losartan on sICAM-1 and TNF-alpha levels in uncomplicated hypertensive patients
    • Sardo MA, Castaldo M, Cinquegrani M, et al. Effects of AT1 receptor antagonist losartan on sICAM-1 and TNF-alpha levels in uncomplicated hypertensive patients. Angiology 2004; 55(2): 195-203.
    • (2004) Angiology , vol.55 , Issue.2 , pp. 195-203
    • Sardo, M.A.1    Castaldo, M.2    Cinquegrani, M.3
  • 252
    • 0037426399 scopus 로고    scopus 로고
    • C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle
    • Wang CH, Li SH, Weisel RD, Fedak PW, Dumont AS, Szmitko P. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation 2003; 107(13): 1783-1790.
    • (2003) Circulation , vol.107 , Issue.13 , pp. 1783-1790
    • Wang, C.H.1    Li, S.H.2    Weisel, R.D.3    Fedak, P.W.4    Dumont, A.S.5    Szmitko, P.6
  • 253
    • 38749090617 scopus 로고    scopus 로고
    • Telmisartan treatment decreasesvisceral fat accumulation and improves serum levels of adiponectin and vascular inflammation markers in Japanese hypertensive patients
    • Chujo D, Yagi K, Asano A, et al. Telmisartan treatment decreasesvisceral fat accumulation and improves serum levels of adiponectin and vascular inflammation markers in Japanese hypertensive patients. Hypertens Res 2007; 30(12): 1205-1210.
    • (2007) Hypertens Res , vol.30 , Issue.12 , pp. 1205-1210
    • Chujo, D.1    Yagi, K.2    Asano, A.3
  • 254
    • 77951921451 scopus 로고    scopus 로고
    • Effects of rosuvastatin combined with olmesartan, irbesartan, or telmisartan on indices of glucose metabolism in Greek adults with impaired fasting glucose, hypertension, and mixed hyperlipidemia: A 24-week, randomized, open-label, prospective study
    • Rizos CV, Milionis HJ, Kostapanos MS, et al. Effects of rosuvastatin combined with olmesartan, irbesartan, or telmisartan on indices of glucose metabolism in Greek adults with impaired fasting glucose, hypertension, and mixed hyperlipidemia: a 24-week, randomized, open-label, prospective study. Clin Ther 2010; 32(3): 492-505.
    • (2010) Clin Ther , vol.32 , Issue.3 , pp. 492-505
    • Rizos, C.V.1    Milionis, H.J.2    Kostapanos, M.S.3
  • 255
    • 0242694573 scopus 로고    scopus 로고
    • Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: Rationale and design of the JUPITER trial
    • Ridker PM; JUPITER Study Group
    • Ridker PM; JUPITER Study Group. Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial. Circulation 2003; 108(19): 2292-2297.
    • (2003) Circulation , vol.108 , Issue.19 , pp. 2292-2297
  • 256
    • 2542479913 scopus 로고    scopus 로고
    • Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension
    • Koh KK, Han SH, Chung WJ, et al. Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension. Am J Cardiol 2004; 93(11): 1432-1435, A10.
    • (2004) Am J Cardiol , vol.93 , Issue.11 , pp. 1432-1435
    • Koh, K.K.1    Han, S.H.2    Chung, W.J.3
  • 257
    • 2542475889 scopus 로고    scopus 로고
    • Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy
    • Yasunari K, Maeda K, Watanabe T, Nakamura M, Yoshikawa J, Asada A. Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy. J Am Coll Cardiol 2004; 43(11): 2116-2123.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.11 , pp. 2116-2123
    • Yasunari, K.1    Maeda, K.2    Watanabe, T.3    Nakamura, M.4    Yoshikawa, J.5    Asada, A.6
  • 258
    • 33745987893 scopus 로고    scopus 로고
    • Valsartan, blood pressure reduction, and C-reactive protein: Primary report of the Val-MARC trial
    • Val-MARC Investigators
    • Ridker PM, Danielson E, Rifai N, Glynn RJ. Val-MARC Investigators. Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial. Hypertension 2006; 48(1): 73-79.
    • (2006) Hypertension , vol.48 , Issue.1 , pp. 73-79
    • Ridker, P.M.1    Danielson, E.2    Rifai, N.3    Glynn, R.J.4
  • 259
    • 42949148238 scopus 로고    scopus 로고
    • Effect of valsartan compared with valsartan/hydrochlorothiazide on plasma levels of cellular adhesion molecules: The Val-MARC trial
    • Conen D, Everett BM, Glynn RJ, Ridker PM. Effect of valsartan compared with valsartan/hydrochlorothiazide on plasma levels of cellular adhesion molecules: the Val-MARC trial. Heart. 2008; 94(3): e13.
    • (2008) Heart , vol.94 , Issue.3
    • Conen, D.1    Everett, B.M.2    Glynn, R.J.3    Ridker, P.M.4
  • 260
    • 34249007221 scopus 로고    scopus 로고
    • Increased inflammatory biomarkers in hypertensive type 2 diabetic patients: Improvement after angiotensin II type 1 receptor blockade
    • Touyz RM, Savoia C, He Y, et al. Increased inflammatory biomarkers in hypertensive type 2 diabetic patients: improvement after angiotensin II type 1 receptor blockade. J Am Soc Hypertens. 2007; 1(3): 189-199.
    • (2007) J Am Soc Hypertens , vol.1 , Issue.3 , pp. 189-199
    • Touyz, R.M.1    Savoia, C.2    He, Y.3
  • 261
    • 13144249129 scopus 로고    scopus 로고
    • Angiotensin II and the endothelium: Diverse signals and effects
    • Watanabe T, Barker TA, Berk BC. Angiotensin II and the endothelium: diverse signals and effects. Hypertension 2005; 45(2): 163-169.
    • (2005) Hypertension , vol.45 , Issue.2 , pp. 163-169
    • Watanabe, T.1    Barker, T.A.2    Berk, B.C.3
  • 262
    • 56349161639 scopus 로고    scopus 로고
    • The angiotensin II type 2 receptor: What is its clinical significance?
    • Schulman IH, Raij L. The angiotensin II type 2 receptor: what is its clinical significance? Curr Hypertens Rep 2008; 10(3): 188-193.
    • (2008) Curr Hypertens Rep , vol.10 , Issue.3 , pp. 188-193
    • Schulman, I.H.1    Raij, L.2
  • 263
    • 57349103077 scopus 로고    scopus 로고
    • Does it matter how hypertension is controlled?
    • Chobanian AV. Does it matter how hypertension is controlled? N Engl J Med 2008; 359 (23): 2485-2488.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2485-2488
    • Chobanian, A.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.