Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 6, 2007, Pages

  Kajiya, Masahito ^a   Hirota, Masanori ^a   Inai, Yousuke ^a   Kiyooka, Takahiko ^a   Morimoto, Taro ^a   Iwasaki, Tatsuo ^a   Endo, Kousuke ^b   Mohri, Satoshi ^a   Shimizu, Juichiro ^a   Yada, Toyotaka ^b   Ogasawara, Yasuo ^b   Naruse, Keiji ^a   Ohe, Tohru ^a   Kajiya, Fumihiko ^a,b  

^a OKAYAMA UNIVERSITY   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Acetylcholine; Catalase; Endothelium derived hyperpolarizing factor; N nitro L arginine methyl ester; Superoxide dimutase; Tetraethylanmonium

Indexed keywords

ACETYLCHOLINE; CATALASE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; LUCIGENIN; MONOCROTALINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SODIUM CHLORIDE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TETRYLAMMONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTERY; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; CHEMOLUMINESCENCE; CONTROLLED STUDY; HOMEOSTASIS; MALE; MECHANICAL STRESS; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PULMONARY HYPERTENSION; RAT; VASODILATATION;

ACETYLCHOLINE; ANIMALS; BIOLOGICAL FACTORS; CATALASE; CORONARY CIRCULATION; CORONARY VESSELS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HEART VENTRICLES; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MICROCIRCULATION; MICROSCOPY, VIDEO; MONOCROTALINE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; SUPEROXIDES; TETRAETHYLAMMONIUM; VASODILATION; VASODILATOR AGENTS;

EID: 34447512854     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00548.2006     Document Type: Article

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