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Volumn 144, Issue 5 SUPPL., 2002, Pages

New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALDOSTERONE ANTAGONIST; DEOXYCORTICOSTERONE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; EPLERENONE; MINERALOCORTICOID RECEPTOR; OXPRENOATE POTASSIUM; PLACEBO; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; SODIUM CHLORIDE; SPIRONOLACTONE;

EID: 0036847322     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1067/mhj.2002.129971     Document Type: Conference Paper
Times cited : (36)

References (17)
  • 1
    • 0030901037 scopus 로고    scopus 로고
    • Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion
    • Okubo S, Niimura F, Nishimura H, et al. Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion. J Clin Invest 1997;99:855-60.
    • (1997) J Clin Invest , vol.99 , pp. 855-860
    • Okubo, S.1    Niimura, F.2    Nishimura, H.3
  • 2
    • 2542624590 scopus 로고
    • Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity
    • Krozowski ZS, Funder JW. Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity. Proc Natl Acad Sci USA 1983;80:6056-60.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6056-6060
    • Krozowski, Z.S.1    Funder, J.W.2
  • 3
    • 0023585013 scopus 로고
    • High affinity aldosterone binding sites (type I receptors) in rat heart
    • Pearce P, Funder JW. High affinity aldosterone binding sites (type I receptors) in rat heart. Clin Exp Pharmacol Physiol 1987;14:859-66.
    • (1987) Clin Exp Pharmacol Physiol , vol.14 , pp. 859-866
    • Pearce, P.1    Funder, J.W.2
  • 4
    • 0023221667 scopus 로고
    • Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor
    • Arriza JL, Weinberger C, Cerelli G, et al. Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science 1987;237:268-75.
    • (1987) Science , vol.237 , pp. 268-275
    • Arriza, J.L.1    Weinberger, C.2    Cerelli, G.3
  • 5
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • Funder JW, Pearce PT, Smith R, et al. Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science 1988;242:583-5.
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3
  • 6
    • 0023761690 scopus 로고
    • Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor
    • Edwards CRW, Stewart PM, Burt D, et al. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 1988;2:986-9.
    • (1988) Lancet , vol.2 , pp. 986-989
    • Edwards, C.R.W.1    Stewart, P.M.2    Burt, D.3
  • 7
    • 0026529495 scopus 로고
    • Central mineralocorticoid receptor antagonism blocks hypertension in Dahl S/JR rats
    • Gomez-Sanchez EP, Fort C, Thwaites D. Central mineralocorticoid receptor antagonism blocks hypertension in Dahl S/JR rats. Am J Physiol 1992;262:E96-9.
    • (1992) Am J Physiol , vol.262
    • Gomez-Sanchez, E.P.1    Fort, C.2    Thwaites, D.3
  • 8
    • 0027081410 scopus 로고
    • Mineralocorticoid excess, dietary sodium, and myocardial fibrosis
    • Brilla CG, Weber KT. Mineralocorticoid excess, dietary sodium, and myocardial fibrosis. J Lab Clin Med 1992;120:893-901.
    • (1992) J Lab Clin Med , vol.120 , pp. 893-901
    • Brilla, C.G.1    Weber, K.T.2
  • 9
    • 0028785677 scopus 로고
    • Determinants of cardiac fibrosis in experimental hypermineralocorticoid states
    • Young M, Head G, Funder J. Determinants of cardiac fibrosis in experimental hypermineralocorticoid states. Am J Physiol 1995;269:E657-62.
    • (1995) Am J Physiol , vol.269
    • Young, M.1    Head, G.2    Funder, J.3
  • 10
    • 0029762716 scopus 로고    scopus 로고
    • High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes
    • Sato A, Funder JW. High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes. Endocrinology 1996;137:4145-53.
    • (1996) Endocrinology , vol.137 , pp. 4145-4153
    • Sato, A.1    Funder, J.W.2
  • 11
    • 0034920217 scopus 로고    scopus 로고
    • Experimental cardiac fibrosis: Differential time course of responses to mineralocorticoid-salt administration
    • Fujisawa G, Dilley R, Fullerton MJ, et al. Experimental cardiac fibrosis: Differential time course of responses to mineralocorticoid-salt administration. Endocrinology 2001;142:3625-31.
    • (2001) Endocrinology , vol.142 , pp. 3625-3631
    • Fujisawa, G.1    Dilley, R.2    Fullerton, M.J.3
  • 12
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999;341:709-17.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 13
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES)
    • Zannad F, Alla F, Dousset B, et al. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). Circulation 2000;102:2700-6.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3
  • 14
    • 0035458773 scopus 로고    scopus 로고
    • Pathophysiological effects of aldosterone in cardiovascular tissues
    • Rocha R, Stier CT Jr. Pathophysiological effects of aldosterone in cardiovascular tissues. Trends Endocrinol Metab 2001;12:308-14.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 308-314
    • Rocha, R.1    Stier C.T., Jr.2
  • 15
    • 0033745021 scopus 로고    scopus 로고
    • Aldosterone: A mediator of myocardial necrosis and renal arteriopathy
    • Rocha R, Stier CT Jr, Kifor I, et al. Aldosterone: A mediator of myocardial necrosis and renal arteriopathy. Endocrinology 2000;141:3871-8.
    • (2000) Endocrinology , vol.141 , pp. 3871-3878
    • Rocha, R.1    Stier C.T., Jr.2    Kifor, I.3
  • 16
    • 0036838616 scopus 로고    scopus 로고
    • Aldosterone induces a vascular inflammatory phenotype in the rat heart
    • Rocha R, Rudolph AE, Frierdich GG, et al. Aldosterone induces a vascular inflammatory phenotype in the rat heart. Am J Physiol Heart Circ Physiol. 2002;283:1802-10.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. 1802-1810
    • Rocha, R.1    Rudolph, A.E.2    Frierdich, G.G.3
  • 17
    • 0035943051 scopus 로고    scopus 로고
    • Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries
    • Ward MR, Kanellakis P, Ramsey D, et al. Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. Circulation 2001;104:467-72.
    • (2001) Circulation , vol.104 , pp. 467-472
    • Ward, M.R.1    Kanellakis, P.2    Ramsey, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.