Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency

New England Journal of Medicine

Volumn 334, Issue 15, 1996, Pages 939-945

  Maschio, Giuseppe ^a,i   Alberti, Daniele ^b   Janin, Gérard ^c   Locatelli, Francesco ^d   Mann, Johannes F E ^e   Motolese, Mario ^b   Ponticelli, Claudio ^f   Ritz, Eberhard ^g   Zucchelli, Pietro ^h  

^a Divisione di Pediatria   (Italy)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Hopital des Chanaux   (France)

^d A MANZONI HOSPITAL   (Italy)

^e Klinikum Schwabing   (Germany)

^f FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^g UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^h UNIVERSITY OF BOLOGNA   (Italy)

ⁱ Ospedale Civile   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENAZEPRIL;

ADULT; AGED; ARTICLE; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HUMAN; INTERSTITIAL NEPHRITIS; KIDNEY POLYCYSTIC DISEASE; MAJOR CLINICAL STUDY; MALE; NEPHROSCLEROSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BENZAZEPINES; BLOOD PRESSURE; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; FEMALE; HUMANS; KIDNEY DISEASES; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 15844368318     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199604113341502     Document Type: Article

References (26)

1. Zatz R, Andersen S, Meyer TW, Dunn BR. Rennke HG, Brenner BM. Lowering of arterial blood pressure limits glomerular sclerosis in rats with renal ablation and in experimental diabetes. Kidney Int Suppl 1987;20 S123-S129.
2. Cartwright ME, Jaenke RS Effects of dietary protein and captopril on glomerular permselectivity in rats with unilateral nephrectomy. Lab Invest 1988;59:492-9.
3. Anderson S, Rennke HG, Brenner BM. Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 1986;77:1993-2000.
4. Jackson B. Johnston CI The contribution of systemic hypertension to progression of chronic renal failure in the rat remnant kidney effect of treatment with an angiotensin converting enzyme inhibitor or a calcium inhibitor. J Hypertens 1988;6495-501.
5. Ravid M, Savin H, Jutrin I, et al. Long-term stabilizing effect of angiotensin-converting enzyme inhibition on plasma creatinine and on proteinuria in normotensive type II diabetic patients Ann Intern Med 1993;118:577-81.
6. Viberti G, Mogensen CE, Groop LC, Paul JF, Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria JAMA 1994;271:275-9.
7. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329 1456-62. [Erratum, N Engl J Med 1993l330:152]
8. Mann JFE. Reisch C, Ritz E Use of angiotensin-converting enzyme inhibitors for the preservation of kidney function. Nephron 1990;55:Suppl I:38-42
9. Rekola S. Bergstrand A, Bucht H Deterioration rate in hypertensive IgA nephropathy comparison of a converting enzyme inhibitor and beta-blocking agents. Nephron 1991;59.57-60
10. Kamper A-L, Strandgaard S, Leyssac PP. Effect of enalapril on the progression of chronic renal failure: a randomized controlled trial. Am J Hypertens 1992;5:423-30
11. Hannedouche T, Landais P. Goldfarb B, et al. Randomized controlled trial of enalapril and beta blockers in non-diabetic chronic renal failure BMJ 1994;309.833-7.
12. Cockcroft DW, Gault MH Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
13. Cook RJ, Sackett DL. The number needed to treat: a clinically useful measure of treatment effect. BMJ 1995;310:452-4.
14. Locatelli F, Alberti D, Graziani G, Buccianti G, Redaelli B, Giangrande A Prospective, randomised, multicentre trial of effect of protein restriction on progression of chronic renal insufficiency. Lancet 1991;337:1299-304.
15. Klahr S, Levey AS, Beck GJ. et al The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. N Engl J Med 1994;330:877-84
16. Maschio G, Oldrizzi L, Rugiu C, et al. Factors affecting progression of renal failure in patients on long-term dietary protein restriction. Kidney Int Suppl 1987;22.S49-S52
17. Agabiti-Rosei E, Rizzoni D, Zulu R, Muiesan L, Motolese M, Muiesan G. Sustained antihypertensive effects of benazepril demonstrated by ambulatory monitoring: placebo-controlled trial at two dosage levels. In: Brunner HR, Salvetti A, Sever PS, eds. Benazepril: profile of a new ACE inhibitor. International congress and symposium series no 166 London: Royal Society of Medicine Services. 1990.59-66.
18. Zucchelli P, Zuccalà A, Borghi M, et al. Long-term comparison between captopril and nifedipine in the progression of renal insufficiency. Kidney Int 1992;42 452-8.
19. Praga M, Hernandez E. Montoyo C, Andres A, Ruilope LM. Rodicio JL Long-term beneficial effects of angiotensin-converting enzyme inhibition in patients with nephrotic proteinuria. Am J Kidney Dis 1992;20:240-8
20. Peterson JC, Burkart J, Greene T, et al The effect of blood pressure control on progression of renal disease depends on level of proteinuria at base-line evaluation. J Am Soc Nephrol 1993;4:Suppl 254A. abstract.
21. Remuzzi A, Petricucci E, Ruggenenti P, Mosconi L, Limonta M, Remuzzi G. Angiotensin converting enzyme inhibition improves glomerular size-selectivity in IgA nephropathy. Kidney Int 1991;39:1267-73
22. Gansevoort RT, Sluiter W, de Zeeuw D, de long PE. The antiproteinuric effect of angiotensin-converting-enzyme inhibition in comparison to that of other antihypertensives in diabetic and non-diabetic renal disease. J Am Soc Nephrol 1994;5:Suppl:329A. abstract.
23. Remuzzi G, Bertani T. Is glomerulosclerosis a consequence of altered glomerular permeability to macromolecules? Kidney Int 1990;38:384-94.
24. Brown JH, Hunt LP, Vites NP, Short CD. Gokal R, Mallick NP. Comparative mortality from cardiovascular disease in patients with chronic renal failure. Nephrol Dial Transplant 1994;9 1136-42.
25. Raine AEG, Margreiter R, Brunner FR, et al. Report on management of renal failure in Europe, XXII, 1991. Nephrol Dial Transplant 1992;7:Suppl 2: 7-35
26. Ambrosioni E, Borghi C, Magnani B The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction N Engl J Med 1995,332:80-5.