Benzofuroquinoline derivatives had remarkable improvement of their selectivity for telomeric g-quadruplex DNA over duplex DNA upon introduction of peptidyl group

Bioconjugate Chemistry

Volumn 23, Issue 9, 2012, Pages 1821-1831

  Long, Yi ^a   Li, Zeng ^a   Tan, Jia Heng ^a   Ou, Tian Miao ^a   Li, Ding ^a   Gu, Lian Quan ^a   Huang, Zhi Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DICHROISM; DNA; ENERGY TRANSFER; FORSTER RESONANCE ENERGY TRANSFER; POPULATION STATISTICS; SURFACE PLASMON RESONANCE;

BINDING AFFINITIES; DUPLEX DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; G-QUADRUPLEXES; INHIBITORY EFFECT; MOLECULAR MODELING STUDIES; QUADRUPLEX-BINDING LIGANDS; QUADRUPLEXES; SURFACE-PLASMON RESONANCE; SYNTHESISED;

CIRCULAR DICHROISM SPECTROSCOPY;

AMINO ACID; CRYPTOLEPINE DERIVATIVE; DOUBLE STRANDED DNA; GUANINE QUADRUPLEX; MOLECULAR SCAFFOLD; PEPTIDYL BENZOFUROQUINOLINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CANCER CELL; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA BINDING; DRUG DESIGN; DRUG SYNTHESIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; MOLECULAR MODEL; PHENOTYPE; SENESCENCE; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE; SYNTHESIS; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 84866354796     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300123m     Document Type: Article

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