Central nervous system endoplasmic reticulum stress in a murine model of Type 2 diabetes

Diabetologia

Volumn 55, Issue 8, 2012, Pages 2276-2284

  Sims Robinson, C ^a   Zhao, S ^a,b   Hur, J ^a   Feldman, E L ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Brain; ER stress; Gene expression; Hippocampus; Microarray; Type 2 diabetes; Unfolded protein response

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; MESSENGER RNA; PROTEIN; X BOX BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOINFORMATICS; CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; DDIT3 GENE; DISEASE ASSOCIATION; DISEASE MODEL; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; HIPPOCAMPUS; HSP90B1 GENE; HSPA5 GENE; MICROARRAY ANALYSIS; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REVIEW; RNA ANALYSIS; UNFOLDED PROTEIN RESPONSE; XBP1 GENE;

ANIMALS; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; RNA, MESSENGER; UNFOLDED PROTEIN RESPONSE;

EID: 84866349146     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2573-6     Document Type: Review

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