High-fat diets, insulin resistance and declining cognitive function

Neurobiology of Aging

Volumn 26, Issue SUPPL., 2005, Pages 42-45

  Greenwood, Carol E ^a,c,d   Winocur, Gordon ^b,e,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Kunin Lunenfeld Applied Research Unit and Department of Food and Nutrition Services and Baycrest Centre for Geriatric Care   (Canada)

^d BAYCREST CENTRE FOR GERIATRIC CARE   (Canada)

^e ROTMAN RESEARCH INSTITUTE   (Canada)

^f TRENT UNIVERSITY   (Canada)

Author keywords

Aging; Cognitive impairment; Dietary fat; Hyperglycemia; Type 2 diabetes mellitus

Indexed keywords

OMEGA 6 FATTY ACID; SATURATED FATTY ACID;

ALZHEIMER DISEASE; BRAIN FUNCTION; COGNITION; COGNITIVE DEFECT; CONFERENCE PAPER; DIETARY INTAKE; FOOD INTAKE; GLUCOSE INTAKE; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; HYPERGLYCEMIA; HYPERINSULINEMIA; INFLAMMATION; INSULIN RESISTANCE; LIPID DIET; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR; TEMPORAL LOBE;

EID: 28444466516     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.08.017     Document Type: Conference Paper

References (50)

1. P. Barberger-Gateau, L. Letenneur, V. Deschamps, K. Peres, J.F. Dartigues, and S. Renaud Fish, meat, and risk of dementia: cohort study Br Med J 325 2002 932 933
2. C. Brayne, L. Gao, and F. Matthews MRC Cognitive Function and Ageing Study. Challenges in the epidemiological investigation of the relationship between physical activity, obesity, diabetes, dementia and depression Neurobiol Aging 26S 2005 S5 S10
3. G.M. Cole, G.P. Lim, F. Yang, B. Teter, A. Begum, and Q. Ma Prevention of Alzheimer's disease: omega 3 fatty acid and phenolic antioxidant interventions Neurobiol Aging 26S 2005 S133 S136
4. J.A. Conquer, M.C. Tierney, J. Zecevic, W.J. Bettger, and R.H. Fisher Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment Lipids 35 2000 1305 1312
5. A. Convit Links between cognitive impairment in insulin resistance: an explanatory model Neurobiol Aging 26S 2005 S31 S35
6. S. Craft Insulin resistance syndrome and Alzheimer's disease: age- and obesity- related effects on memory, amyloid, and inflammation Neurobiol Aging 26S 2005 S65 S69
7. S. Craft, and G.S. Watson Insulin and neurodegenerative disease: shared and specific mechanisms Lancet Neurol. 3 2004 169 178
8. M.F. Elias, P.K. Elias, L.M. Sullivan, and P.A. Wolf D'Agostino RB. Obesity, diabetes and cognitive deficit: the Framingham Heart Study Neurobiol Aging 26S 2005 S11 S16
9. M.J. Engelhart, M.I. Geerlings, A. Ruitenberg, J.C. Van Swieten, A. Hofman, and J.C. Witteman Diet and risk of dementia: does fat matter? The Rotterdam Study Neurology 59 2000 1915 1921 [see comment]
10. K. Esposito, F. Nappo, R. Marfella, G. Giugliano, F. Giugliano, and M. Ciotola Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress Circulation 106 2002 2067 2072 [see comment]
11. D. Figlewicz, P. Szot, and M.R. Greenwood Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats Physiol Behav 47 1990 325 330
12. P. Gold Glucose modulation of memory storage processing Behav Neural Biol 45 1986 342 349
13. P.E. Gold Role of glucose in regulating the brain and cognition Am J Clin Nutr 61 1995 987S 995S
14. C.E. Greenwood Dietary carbohydrate, glucose regulation, and cognitive performance in elderly persons Nutr Rev 61 2003 S68 S74
15. C.E. Greenwood, R.J. Kaplan, S. Hebblethwaite, and D.J. Jenkins Carbohydrate-induced memory impairment in adults with type 2 diabetes Diabetes Care 26 2003 1961 1966
16. C.E. Greenwood, and G. Winocur Glucose treatment reduces memory deficits in young adult rats fed high fat diets Neurobiol Learning Memory 75 2001 179 189
17. N Grinberg, L. Hasher, and C.E. Greenwood The cognitive syndrome. An emerging cluster of circadian, metabolic and endocrine factors in cognition J Nutr Health Aging 7 2003 237
18. L. Hasher, R.T. Zacks, and C.P. May Inhibitory control, circadian arousal, and age D. Gopher A. Koriat Attention and performance. XVII. Cognitive regulation of performance: interaction of theory and application 1999 MIT Press Cambridge, MA 653 675
19. S. Kalmijn, E.J. Feskens, L.J. Launer, and D. Kromhout Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men Am J Epidemiol 145 1997 33 41
20. S. Kalmijn, L.J. Launer, A. Ott, J.C. Witteman, A. Hofman, and M.M. Breteler Dietary fat intake and the risk of incident dementia in the Rotterdam Study Ann Neurol 42 1997 776 782
21. S. Kalmijn, M.P. van Boxtel, M. Ocke, W.M. Verschuren, D. Kromhout, and L.J. Launer Dietary intake of fatty acids and fish in relation to cognitive performance at middle age Neurology 62 2004 275 280
22. R. Kaplan, and C. Greenwood Dietary saturated fatty acids and brain function Neurochem Res 23 1998 615 626
23. R.J. Kaplan, C.E. Greenwood, G. Winocur, and T.M. Wolever Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates Am J Clin Nutr 72 2000 825 836
24. R.J. Kaplan, C.E. Greenwood, G. Winocur, and T.M.S. Wolever Dietary protein, carbohydrate and fat enhance memory performance in the healthy elderly Am J Clin Nutr 74 2001 687 693
25. M. Korbonits, P.J. Trainer, M.L. Nelson, I. Howse, P.G. Kopelman, and G.M. Besser Differential stimulation of cortisol and dehydroepiandrosterone levels by food in obese and normal subjects: relation to body fat distribution Clin Endocrinol 45 1996 699 706
26. S. Larrieu, L. Letenneur, C. Helmer, J.F. Dartigues, and P. Barberger-Gateau Nutritional factors and risk of incident dementia in the PAQUID longitudinal cohort J Nutr Health Aging 8 2004 150 154
27. D. Laurin, R. Verreault, J. Lindsay, E. Dewailly, and B.J. Holub Omega-3 fatty acids and risk of cognitive impairment and dementia J Alzheimer's Dis 5 2003 315 322
28. J.A. Luchsinger, M.X. Tang, S. Shea, and R. Mayeux Caloric intake and the risk of Alzheimer disease Arch Neurol 59 2002 1258 1263
29. S.J. Lupien, S. Gaudreau, B.M. Tchiteya, F. Maheu, S. Sharma, and N.P. Nair Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity J Clin Endocrinol Metab 82 1997 2070 2075
30. A.L. McCall Altered glycemia and brain - update and potential relevance to the aging brain Neurobiol Aging 26S 2005 S70 S75
31. C. Messier Glucose improvement of memory: a review Eur J Pharmacol 490 2004 33 57
32. C. Messier Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging Neurobiol Aging 26S 2005 S26 S30
33. L. Morgan, S. Hampton, M. Gibbs, and J. Arendt Circadian aspects of postprandial metabolism Chronobiol Int 20 2003 795 808
34. M.C. Morris, D.A. Evans, J.L. Bienias, C.C. Tangney, D.A. Bennett, and N. Aggarwal Dietary fats and the risk of incident Alzheimer disease Arch Neurol 60 2003 194 200
35. M.C. Morris, D.A. Evans, J.L. Bienias, C.C. Tangney, D.A. Bennett, and R.S. Wilson Consumption of fish and n - 3 fatty acids and risk of incident Alzheimer disease Arch Neurol 60 2003 940 946
36. M.C. Morris, D.A. Evans, J.L. Bienias, C.C. Tangney, and R.S. Wilson Dietary fat intake and 6-year cognitive change in an older biracial community population Neurology 62 2004 1573 1579
37. F. Nappo, K. Esposito, M. Cioffi, G. Giugliano, A.M. Molinari, and G. Paolisso Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals J Am Coll Cardiol 39 2002 1145 1150
38. R.M. Ortega, A.M. Requejo, P. Andres, A.M. Lopez-Sobaler, M.E. Quintas, and M.R. Redondo Dietary intake and cognitive function in a group of elderly people Am J Clin Nutr 66 1997 803 809
39. L. Reagan Neuronal insulin signal transduction mechanisms in diabetes phenotypes Neurobiol Aging 26S 2005 S56 S59
40. L.P. Reagan Glucose, stress, and hippocampal neuronal vulnerability Int Rev Neurobiol 51 2002 289 324
41. A. Reichenberg, R. Yirmiya, A. Schuld, T. Kraus, M. Haack, and A. Morag Cytokine-associated emotional and cognitive disturbances in humans Arch Gen Psychiat 58 2001 445 452
42. R. Rosmond, and P. Bjorntorp The hypothalamic-pituitary-adrenal axis activity as a predictor of cardiovascular disease, type 2 diabetes and stroke J Int. Med 247 2000 188 197
43. A.J. Sommerfield, I.J. Deary, and B.M. Frier Acute hyperglycemia alters mood state and impairs cognitive performance in people with type 2 diabetes Diabetes Care 27 2004 2335 2340
44. J. Spranger, A. Kroke, M. Mohlig, K. Hoffmann, M.M. Bergmann, and M. Ristow Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study Diabetes 52 2003 812 817
45. C. Tsigos, R.J. Young, and A. White Diabetic neuropathy is associated with increased activity of the hypothalamic-pituitary-adrenal axis J Clin Endocrinol Metab 76 1993 554 558
46. A.M. Tully, H.M. Roche, R. Doyle, C. Fallon, I. Bruce, and B. Lawlor Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study Br J Nutr 89 2003 483 489
47. G. Watson, and S. Craft Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease Eur J Pharmacol 490 2004 97 113
48. G. Winocur, and C.E. Greenwood Studies of the effects of high fat diets on cognitive function in a rat model Neurobiol Aging 26S 2005 S46 S49
49. Winocur G, Greenwood CE, Piroli GG, Grillo CA, Reznikov LR, Reagan LP, et al. Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav Neurosci, in press.
50. G. Winocur, and L. Hasher Aging and time-of-day effects on cognition in rats Behav Neurosci 113 1999 991 997