Crystal structure of human aurora B in complex with INCENP and VX-680

Journal of Medicinal Chemistry

Volumn 55, Issue 17, 2012, Pages 7841-7848

  Elkins, Jonathan M ^a   Santaguida, Stefano ^b,e   Musacchio, Andrea ^b,c,d   Knapp, Stefan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; INCENP PROTEIN; NUCLEAR PROTEIN; TOZASERTIB; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DRUG CONFORMATION; DRUG PROTEIN BINDING; ENZYME ACTIVATION; IC 50; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; ULTRACENTRIFUGATION; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; CHROMOSOMAL PROTEINS, NON-HISTONE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PIPERAZINES; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84866328067     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3008954     Document Type: Article

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