메뉴 건너뛰기




Volumn 2012, Issue , 2012, Pages

Fibroblast growth factor receptor 2: Expression, roles, and potential as a novel molecular target for colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84866262456     PISSN: None     EISSN: 2042003X     Source Type: Journal    
DOI: 10.1155/2012/574768     Document Type: Review
Times cited : (48)

References (79)
  • 1
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R., Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA-Cancer Journal for Clinicians 2011 61 4 212 236
    • (2011) CA-Cancer Journal for Clinicians , vol.61 , Issue.4 , pp. 212-236
    • Siegel, R.1
  • 2
    • 67349152647 scopus 로고    scopus 로고
    • Treatment in advanced colorectal cancer: What, when and how?
    • 2-s2.0-67349152647 10.1038/sj.bjc.6605061
    • Chau I., Cunningham D., Treatment in advanced colorectal cancer: what, when and how? British Journal of Cancer 2009 100 11 1704 1719 2-s2.0-67349152647 10.1038/sj.bjc.6605061
    • (2009) British Journal of Cancer , vol.100 , Issue.11 , pp. 1704-1719
    • Chau, I.1    Cunningham, D.2
  • 3
    • 35349007958 scopus 로고    scopus 로고
    • The Fgf families in humans, mice, and zebrafish: Their evolutional processes and roles in development, metabolism, and disease
    • DOI 10.1248/bpb.30.1819
    • Itoh N., The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease. Biological and Pharmaceutical Bulletin 2007 30 10 1819 1825 2-s2.0-35349007958 10.1248/bpb.30.1819 (Pubitemid 47607758)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.10 , pp. 1819-1825
    • Itoh, N.1
  • 4
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • DOI 10.1016/j.tig.2004.08.007, PII S0168952504002410
    • Itoh N., Ornitz D. M., Evolution of the Fgf and Fgfr gene families. Trends in Genetics 2004 20 11 563 569 2-s2.0-4744372082 10.1016/j.tig.2004.08. 007 (Pubitemid 39314564)
    • (2004) Trends in Genetics , vol.20 , Issue.11 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 5
    • 33751113439 scopus 로고    scopus 로고
    • FGF signaling network in the gastrointestinal tract (Review)
    • 2-s2.0-33751113439
    • Katoh M., Katoh M., FGF signaling network in the gastrointestinal tract (Review). International Journal of Oncology 2006 29 1 163 168 2-s2.0-33751113439
    • (2006) International Journal of Oncology , vol.29 , Issue.1 , pp. 163-168
    • Katoh, M.1    Katoh, M.2
  • 6
    • 0033050810 scopus 로고    scopus 로고
    • Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma
    • DOI 10.1002/(SICI)1097-0215(19990719)82:2<298::AID-IJC23>3.0.CO;2-9
    • Jayson G. C., Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinoma. International Journal of Cancer 1999 82 2 298 304 (Pubitemid 29293792)
    • (1999) International Journal of Cancer , vol.82 , Issue.2 , pp. 298-304
    • Jayson, G.C.1    Vives, C.2    Paraskeva, C.3    Schofield, K.4    Coutts, J.5    Fleetwood, A.6    Gallagher, J.T.7
  • 8
    • 0035328856 scopus 로고    scopus 로고
    • Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers
    • 2-s2.0-0035328856
    • Jang J. H., Shin K. H., Park J. G., Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers. Cancer Research 2001 61 9 3541 3543 2-s2.0-0035328856
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3541-3543
    • Jang, J.H.1    Shin, K.H.2    Park, J.G.3
  • 10
    • 16244416568 scopus 로고    scopus 로고
    • Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer
    • 2-s2.0-16244416568
    • Yoshino M., Ishiwata T., Watanabe M., Komine O., Shibuya T., Tokunaga A., Naito Z., Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer. Oncology Reports 2005 13 2 247 252 2-s2.0-16244416568
    • (2005) Oncology Reports , vol.13 , Issue.2 , pp. 247-252
    • Yoshino, M.1    Ishiwata, T.2    Watanabe, M.3    Komine, O.4    Shibuya, T.5    Tokunaga, A.6    Naito, Z.7
  • 14
    • 57349198006 scopus 로고    scopus 로고
    • Novel breast cancer risk alleles and endometrial cancer risk
    • 2-s2.0-57349198006 10.1002/ijc.23862
    • McGrath M., Lee I. M., Buring J., Hunter D. J., De Vivo I., Novel breast cancer risk alleles and endometrial cancer risk. International Journal of Cancer 2008 123 12 2961 2964 2-s2.0-57349198006 10.1002/ijc.23862
    • (2008) International Journal of Cancer , vol.123 , Issue.12 , pp. 2961-2964
    • McGrath, M.1    Lee, I.M.2    Buring, J.3    Hunter, D.J.4    De Vivo, I.5
  • 15
    • 52049086201 scopus 로고    scopus 로고
    • Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
    • 2-s2.0-52049086201 10.1158/0008-5472.CAN-08-0770
    • Byron S. A., Gartside M. G., Wellens C. L., Mallon M. A., Keenan J. B., Powell M. A., Goodfellow P. J., Pollock P. M., Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation. Cancer Research 2008 68 17 6902 6907 2-s2.0-52049086201 10.1158/0008-5472.CAN-08-0770
    • (2008) Cancer Research , vol.68 , Issue.17 , pp. 6902-6907
    • Byron, S.A.1    Gartside, M.G.2    Wellens, C.L.3    Mallon, M.A.4    Keenan, J.B.5    Powell, M.A.6    Goodfellow, P.J.7    Pollock, P.M.8
  • 16
    • 65349087952 scopus 로고    scopus 로고
    • FGFR2 as a molecular target in endometrial cancer
    • 2-s2.0-65349087952 10.2217/14796694.5.1.27
    • Byron S. A., Pollock P. M., FGFR2 as a molecular target in endometrial cancer. Future Oncology 2009 5 1 27 32 2-s2.0-65349087952 10.2217/14796694.5.1. 27
    • (2009) Future Oncology , vol.5 , Issue.1 , pp. 27-32
    • Byron, S.A.1    Pollock, P.M.2
  • 17
    • 64249151246 scopus 로고    scopus 로고
    • FGFR2-related pathogenesis and FGFR2-targeted therapeutics (review)
    • 2-s2.0-64249151246 10.3892/ijmm00000132
    • Katoh Y., Katoh M., FGFR2-related pathogenesis and FGFR2-targeted therapeutics (review). International Journal of Molecular Medicine 2009 23 3 307 311 2-s2.0-64249151246 10.3892/ijmm00000132
    • (2009) International Journal of Molecular Medicine , vol.23 , Issue.3 , pp. 307-311
    • Katoh, Y.1    Katoh, M.2
  • 18
    • 48749094526 scopus 로고    scopus 로고
    • Cancer genomics and genetics of FGFR2 (Review)
    • 2-s2.0-48749094526 10.3892/ijo00000001
    • Katoh M., Cancer genomics and genetics of FGFR2 (Review). International Journal of Oncology 2008 33 2 233 237 2-s2.0-48749094526 10.3892/ijo00000001
    • (2008) International Journal of Oncology , vol.33 , Issue.2 , pp. 233-237
    • Katoh, M.1
  • 19
    • 18144383021 scopus 로고    scopus 로고
    • Cellular signaling by fibroblast growth factor receptors
    • DOI 10.1016/j.cytogfr.2005.01.001
    • Eswarakumar V. P., Lax I., Schlessinger J., Cellular signaling by fibroblast growth factor receptors. Cytokine and Growth Factor Reviews 2005 16 2 139 149 2-s2.0-18144383021 10.1016/j.cytogfr.2005.01.001 (Pubitemid 40616112)
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , Issue.2 SPEC. ISSUE , pp. 139-149
    • Eswarakumar, V.P.1    Lax, I.2    Schlessinger, J.3
  • 20
    • 31544441973 scopus 로고    scopus 로고
    • Characterization of sequences and mechanisms through which ISE/ISS-3 regulates FGFR2 splicing
    • DOI 10.1093/nar/gkj407
    • Hovhannisyan R. H., Warzecha C. C., Carstens R. P., Characterization of sequences and mechanisms through which ISE/ISS-3 regulates FGFR2 splicing. Nucleic Acids Research 2006 34 1 373 385 2-s2.0-31544441973 10.1093/nar/gkj407 (Pubitemid 43160060)
    • (2006) Nucleic Acids Research , vol.34 , Issue.1 , pp. 373-385
    • Hovhannisyan, R.H.1    Warzecha, C.C.2    Carstens, R.P.3
  • 21
    • 32044467372 scopus 로고    scopus 로고
    • Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice
    • DOI 10.1128/MCB.26.4.1209-1222.2006
    • Baraniak A. P., Chen J. R., Garcia-Blanco M. A., Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. Molecular and Cellular Biology 2006 26 4 1209 1222 2-s2.0-32044467372 10.1128/MCB.26.4.1209-1222.2006 (Pubitemid 43202550)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.4 , pp. 1209-1222
    • Baraniak, A.P.1    Chen, J.R.2    Garcia-Blanco, M.A.3
  • 22
    • 61649087689 scopus 로고    scopus 로고
    • ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
    • 2-s2.0-61649087689 10.1016/j.molcel.2009.01.025
    • Warzecha C. C., Sato T. K., Nabet B., Hogenesch J. B., Carstens R. P., ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Molecular Cell 2009 33 5 591 601 2-s2.0-61649087689 10.1016/j.molcel.2009.01.025
    • (2009) Molecular Cell , vol.33 , Issue.5 , pp. 591-601
    • Warzecha, C.C.1    Sato, T.K.2    Nabet, B.3    Hogenesch, J.B.4    Carstens, R.P.5
  • 23
    • 11144328200 scopus 로고    scopus 로고
    • A novel intronic cis element, ISE/ISS-3, regulates rat fibroblast growth factor receptor 2 splicing through activation of an upstream exon and repression of a downstream exon containing a noncanonical branch point sequence
    • DOI 10.1128/MCB.25.1.250-263.2005
    • Hovhannisyan R. H., Carstens R. P., A novel intronic cis element, ISE/ISS-3, regulates rat fibroblast growth factor receptor 2 splicing through activation of an upstream exon and repression of a downstream exon containing a noncanonical branch point sequence. Molecular and Cellular Biology 2005 25 1 250 263 2-s2.0-11144328200 10.1128/MCB.25.1.250-263.2005 (Pubitemid 40039816)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.1 , pp. 250-263
    • Hovhannisyan, R.H.1    Carstens, R.P.2
  • 24
    • 0027199056 scopus 로고
    • Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)
    • DOI 10.1006/dbio.1993.1205
    • Orr-Urtreger A., Bedford M. T., Burakova T., Arman E., Zimmer Y., Yayon A., Givol D., Lonai P., Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Developmental Biology 1993 158 2 475 486 2-s2.0-0027199056 10.1006/dbio.1993.1205 (Pubitemid 23243904)
    • (1993) Developmental Biology , vol.158 , Issue.2 , pp. 475-486
    • Orr-Urtreger, A.1    Bedford, M.T.2    Burakova, T.3    Arman, E.4    Zimmer, Y.5    Yayon, A.6    Givol, D.7    Lonai, P.8
  • 26
    • 18144423534 scopus 로고    scopus 로고
    • Structural basis for fibroblast growth factor receptor activation
    • DOI 10.1016/j.cytogfr.2005.01.008
    • Mohammadi M., Olsen S. K., Ibrahimi O. A., Structural basis for fibroblast growth factor receptor activation. Cytokine and Growth Factor Reviews 2005 16 2 107 137 2-s2.0-18144423534 10.1016/j.cytogfr.2005.01.008 (Pubitemid 40616111)
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , Issue.2 SPEC. ISSUE , pp. 107-137
    • Mohammadi, M.1    Olsen, S.K.2    Ibrahimi, O.A.3
  • 27
    • 0029143960 scopus 로고
    • Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction
    • 2-s2.0-0029143960
    • Friesel R. E., Maciag T., Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction. FASEB Journal 1995 9 10 919 925 2-s2.0-0029143960
    • (1995) FASEB Journal , vol.9 , Issue.10 , pp. 919-925
    • Friesel, R.E.1    MacIag, T.2
  • 28
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
    • Kouhara H., Hadari Y. R., Spivak-Kroizman T., Schilling J., Bar-Sagi D., Lax I., Schlessinger J., A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 1997 89 5 693 702 2-s2.0-0030706168 (Pubitemid 27516172)
    • (1997) Cell , vol.89 , Issue.5 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.R.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 29
    • 0028305121 scopus 로고
    • Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity
    • Itoh H., Hattori Y., Sakamoto H., Ishii H., Kishi T., Sasaki H., Yoshida T., Koono M., Sugimura T., Terada M., Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity. Cancer Research 1994 54 12 3237 3241 2-s2.0-0028305121 (Pubitemid 24208935)
    • (1994) Cancer Research , vol.54 , Issue.12 , pp. 3237-3241
    • Itoh, H.1    Hattori, Y.2    Sakamoto, H.3    Ishii, H.4    Kishi, T.5    Sasaki, H.6    Yoshida, T.7    Koono, M.8    Sugimura, T.9    Terada, M.10
  • 30
    • 40949090037 scopus 로고    scopus 로고
    • Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis
    • DOI 10.1158/1541-7786.MCR-07-0187
    • Cha J. Y., Lambert Q. T., Reuther G. W., Der C. J., Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis. Molecular Cancer Research 2008 6 3 435 445 2-s2.0-40949090037 10.1158/1541-7786.MCR-07-0187 (Pubitemid 351416534)
    • (2008) Molecular Cancer Research , vol.6 , Issue.3 , pp. 435-445
    • Cha, J.Y.1    Lambert, Q.T.2    Reuther, G.W.3    Der, C.J.4
  • 31
    • 69449083319 scopus 로고    scopus 로고
    • Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer
    • 2-s2.0-69449083319 10.1210/me.2009-0071
    • Zhu X., Asa S. L., Ezzat S., Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer. Molecular Endocrinology 2009 23 9 1397 1405 2-s2.0-69449083319 10.1210/me.2009-0071
    • (2009) Molecular Endocrinology , vol.23 , Issue.9 , pp. 1397-1405
    • Zhu, X.1    Asa, S.L.2    Ezzat, S.3
  • 33
    • 34250829395 scopus 로고    scopus 로고
    • Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
    • DOI 10.1038/sj.onc.1210529, PII 1210529
    • Pollock P. M., Gartside M. G., Dejeza L. C., Powell M. A., Mallon M. A., Davies H., Mohammadi M., Futreal P. A., Stratton M. R., Trent J. M., Goodfellow P. J., Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Oncogene 2007 26 50 7158 7162 2-s2.0-34250829395 10.1038/sj.onc. 1210529 (Pubitemid 350059681)
    • (2007) Oncogene , vol.26 , Issue.50 , pp. 7158-7162
    • Pollock, P.M.1    Gartside, M.G.2    Dejeza, L.C.3    Powell, M.A.4    Mallon, M.A.5    Davies, H.6    Mohammadi, M.7    Futreal, P.A.8    Stratton, M.R.9    Trent, J.M.10    Goodfellow, P.J.11
  • 34
    • 0025778485 scopus 로고
    • BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers
    • Adnane J., Gaudray P., Dionne C. A., Crumley G., Jaye M., Schlessinger J., Jeanteur P., Birnbaum D., Theillet C., BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers. Oncogene 1991 6 4 659 663 2-s2.0-0025778485 (Pubitemid 21924133)
    • (1991) Oncogene , vol.6 , Issue.4 , pp. 659-663
    • Adnane, J.1    Gaudray, P.2    Dionne, C.A.3    Crumley, G.4    Jaye, M.5    Schlessinger, J.6    Jeanteur, P.7    Birnbaum, D.8    Theillet, C.9
  • 35
    • 58749107496 scopus 로고    scopus 로고
    • Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma
    • Gartside M. G., Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Molecular Cancer Research 2009 7 1 41 54
    • (2009) Molecular Cancer Research , vol.7 , Issue.1 , pp. 41-54
    • Gartside, M.G.1
  • 36
    • 0031577732 scopus 로고    scopus 로고
    • Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer
    • Carstens R. P., Eaton J. V., Krigman H. R., Walther P. J., Garcia-Blanco M. A., Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer. Oncogene 1997 15 25 3059 3065 2-s2.0-0031577732 (Pubitemid 28043485)
    • (1997) Oncogene , vol.15 , Issue.25 , pp. 3059-3065
    • Carstens, R.P.1    Eaton, J.V.2    Krigman, H.R.3    Walther, P.J.4    Garcia-Blanco, M.A.5
  • 37
    • 36048942703 scopus 로고    scopus 로고
    • Aberrant fibroblast growth factor receptor signaling in bladder and other cancers
    • DOI 10.1111/j.1432-0436.2007.00210.x
    • Chaffer C. L., Dopheide B., Savagner P., Thompson E. W., Williams E. D., Aberrant fibroblast growth factor receptor signaling in bladder and other cancers. Differentiation 2007 75 9 831 842 2-s2.0-36048942703 10.1111/j.1432-0436.2007.00210.x (Pubitemid 350086171)
    • (2007) Differentiation , vol.75 , Issue.9 , pp. 831-842
    • Chaffer, C.L.1    Dopheide, B.2    Savagner, P.3    Thompson, E.W.4    Williams, E.D.5
  • 38
    • 33845809125 scopus 로고    scopus 로고
    • Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
    • DOI 10.1158/0008-5472.CAN-06-2044
    • Chaffer C. L., Brennan J. P., Slavin J. L., Blick T., Thompson E. W., Williams E. D., Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2. Cancer Research 2006 66 23 11271 11278 2-s2.0-33845809125 10.1158/0008-5472.CAN-06-2044 (Pubitemid 46009956)
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11271-11278
    • Chaffer, C.L.1    Brennan, J.P.2    Slavin, J.L.3    Blick, T.4    Thompson, E.W.5    Williams, E.D.6
  • 40
    • 70349245552 scopus 로고    scopus 로고
    • FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: Results of a case control study in Japan
    • 2-s2.0-70349245552 10.1002/ijc.24505
    • Kawase T., Matsuo K., Suzuki T., Hiraki A., Watanabe M., Iwata H., Tanaka H., Tajima K., FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: results of a case control study in Japan. International Journal of Cancer 2009 125 8 1946 1952 2-s2.0-70349245552 10.1002/ijc.24505
    • (2009) International Journal of Cancer , vol.125 , Issue.8 , pp. 1946-1952
    • Kawase, T.1    Matsuo, K.2    Suzuki, T.3    Hiraki, A.4    Watanabe, M.5    Iwata, H.6    Tanaka, H.7    Tajima, K.8
  • 41
    • 0026696081 scopus 로고
    • Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues
    • 2-s2.0-0026696081
    • Luqmani Y. A., Graham M., Coombes R. C., Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues. British Journal of Cancer 1992 66 2 273 280 2-s2.0-0026696081
    • (1992) British Journal of Cancer , vol.66 , Issue.2 , pp. 273-280
    • Luqmani, Y.A.1    Graham, M.2    Coombes, R.C.3
  • 42
    • 40249118869 scopus 로고    scopus 로고
    • Expression of keratinocyte growth factor and its receptor in human endometrial cancer in cooperation with steroid hormones
    • Ishikawa A., Kudo M., Nakazawa N., Onda M., Ishiwata T., Takeshita T., Naito Z., Expression of keratinocyte growth factor and its receptor in human endometrial cancer in cooperation with steroid hormones. International Journal of Oncology 2008 32 3 565 574 2-s2.0-40249118869 (Pubitemid 351330462)
    • (2008) International Journal of Oncology , vol.32 , Issue.3 , pp. 565-574
    • Ishikawa, A.1    Kudo, M.2    Nakazawa, N.3    Onda, M.4    Ishiwata, T.5    Takeshita, T.6    Naito, Z.7
  • 43
    • 16544378971 scopus 로고    scopus 로고
    • Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer
    • 2-s2.0-16544378971
    • Kurban G., Ishiwata T., Kudo M., Yokoyama M., Sugisaki Y., Naito Z., Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer. Oncology Reports 2004 11 5 987 991 2-s2.0-16544378971
    • (2004) Oncology Reports , vol.11 , Issue.5 , pp. 987-991
    • Kurban, G.1    Ishiwata, T.2    Kudo, M.3    Yokoyama, M.4    Sugisaki, Y.5    Naito, Z.6
  • 44
    • 75449096965 scopus 로고    scopus 로고
    • Expression of fibroblast growth factor receptor 2 IIIc in human uterine cervical intraepithelial neoplasia and cervical cancer
    • 2-s2.0-75449096965 10.3892/ijo-00000504
    • Kawase R., Ishiwata T., Matsuda Y., Onda M., Kudo M., Takeshita T., Naito Z., Expression of fibroblast growth factor receptor 2 IIIc in human uterine cervical intraepithelial neoplasia and cervical cancer. International Journal of Oncology 2010 36 2 331 340 2-s2.0-75449096965 10.3892/ijo-00000504
    • (2010) International Journal of Oncology , vol.36 , Issue.2 , pp. 331-340
    • Kawase, R.1    Ishiwata, T.2    Matsuda, Y.3    Onda, M.4    Kudo, M.5    Takeshita, T.6    Naito, Z.7
  • 45
    • 4544233936 scopus 로고    scopus 로고
    • Expression of keratinocyte growth factor/fibroblast growth factor-7 and its receptor in human lung cancer: Correlation with tumour proliferative activity and patient prognosis
    • DOI 10.1002/path.1617
    • Yamayoshi T., Nagayasu T., Matsumoto K., Abo T., Hishikawa Y., Koji T., Expression of keratinocyte growth factor/fibroblast growth factor-7 and its receptor in human lung cancer: correlation with tumour proliferative activity and patient prognosis. Journal of Pathology 2004 204 1 110 118 2-s2.0-4544233936 10.1002/path.1617 (Pubitemid 39214488)
    • (2004) Journal of Pathology , vol.204 , Issue.1 , pp. 110-118
    • Yamayoshi, T.1    Nagayasu, T.2    Matsumoto, K.3    Abo, T.4    Hishikawa, Y.5    Koji, T.6
  • 48
    • 0031872092 scopus 로고    scopus 로고
    • Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer
    • Ishiwata T., Friess H., Büchler M. W., Lopez M. E., Korc M., Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer. American Journal of Pathology 1998 153 1 213 222 2-s2.0-0031872092 (Pubitemid 28317524)
    • (1998) American Journal of Pathology , vol.153 , Issue.1 , pp. 213-222
    • Ishiwata, T.1    Friess, H.2    Buchler, M.W.3    Lopez, M.E.4    Korc, M.5
  • 49
    • 34447318647 scopus 로고    scopus 로고
    • Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer
    • DOI 10.2353/ajpath.2007.060935
    • Cho K., Ishiwata T., Uchida E., Nakazawa N., Korc M., Naito Z., Tajiri T., Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer. American Journal of Pathology 2007 170 6 1964 1974 2-s2.0-34447318647 10.2353/ajpath.2007.060935 (Pubitemid 47339270)
    • (2007) American Journal of Pathology , vol.170 , Issue.6 , pp. 1964-1974
    • Cho, K.1    Ishiwata, T.2    Uchida, E.3    Nakazawa, N.4    Korc, M.5    Naito, Z.6    Tajiri, T.7
  • 50
    • 0033948164 scopus 로고    scopus 로고
    • Overexpression of keratinocyte growth factor in cancer cells and enterochromaffin cells in human colorectal cancer
    • DOI 10.1046/j.1440-1827.2000.01054.x
    • Watanabe M., Ishiwata T., Nishigai K., Moriyama Y., Asano G., Overexpression of keratinocyte growth factor in cancer cells and enterochromaffin cells in human colorectal cancer. Pathology International 2000 50 5 363 372 2-s2.0-0033948164 10.1046/j.1440-1827.2000.01054.x (Pubitemid 30451479)
    • (2000) Pathology International , vol.50 , Issue.5 , pp. 363-372
    • Watanabe, M.1    Ishiwata, T.2    Nishigai, K.3    Moriyama, Y.4    Asano, G.5
  • 51
    • 0035490428 scopus 로고    scopus 로고
    • Expression of fibroblast growth factor (FGF)-10 in human colorectal adenocarcinoma cells
    • 2-s2.0-0035490428
    • Matsuike A., Ishiwata T., Watanabe M., Asano G., Expression of fibroblast growth factor (FGF)-10 in human colorectal adenocarcinoma cells. Journal of Nippon Medical School 2001 68 5 397 404 2-s2.0-0035490428
    • (2001) Journal of Nippon Medical School , vol.68 , Issue.5 , pp. 397-404
    • Matsuike, A.1    Ishiwata, T.2    Watanabe, M.3    Asano, G.4
  • 53
    • 79960845455 scopus 로고    scopus 로고
    • Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: A potential therapeutic target in colorectal cancer
    • 2-s2.0-79960845455 10.1016/j.canlet.2011.06.009
    • Matsuda Y., Ishiwata T., Yamahatsu K., Kawahara K., Hagio M., Peng W. X., Yamamoto T., Nakazawa N., Seya T., Ohaki Y., Naito Z., Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: a potential therapeutic target in colorectal cancer. Cancer Letters 2011 309 2 209 219 2-s2.0-79960845455 10.1016/j.canlet.2011.06.009
    • (2011) Cancer Letters , vol.309 , Issue.2 , pp. 209-219
    • Matsuda, Y.1    Ishiwata, T.2    Yamahatsu, K.3    Kawahara, K.4    Hagio, M.5    Peng, W.X.6    Yamamoto, T.7    Nakazawa, N.8    Seya, T.9    Ohaki, Y.10    Naito, Z.11
  • 54
    • 2642532099 scopus 로고    scopus 로고
    • Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells
    • DOI 10.1002/jcp.10385
    • Visco V., Belleudi F., Marchese C., Leone L., Aimati L., Cardinali G., Kovacs D., Frati L., Torrisi M. R., Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells. Journal of Cellular Physiology 2004 200 1 31 44 2-s2.0-2642532099 10.1002/jcp.10385 (Pubitemid 38720619)
    • (2004) Journal of Cellular Physiology , vol.200 , Issue.1 , pp. 31-44
    • Visco, V.1    Belleudi, F.2    Marchese, C.3    Leone, L.4    Aimati, L.5    Cardinali, G.6    Kovacs, D.7    Frati, L.8    Torrisi, M.R.9
  • 55
    • 0034113377 scopus 로고    scopus 로고
    • Expression of keratinocyte growth factor and its receptor in colorectal cancer
    • Otte J. M., Expression of keratinocyte growth factor and its receptor in colorectal cancer. European Journal of Clinical Investigation 2000 30 3 222 229
    • (2000) European Journal of Clinical Investigation , vol.30 , Issue.3 , pp. 222-229
    • Otte, J.M.1
  • 56
    • 64549087241 scopus 로고    scopus 로고
    • Keratinocyte growth factor induces vascular endothelial growth factor - A expression in colorectal cancer cells
    • 2-s2.0-64549087241 10.3892/ijo00000158
    • Narita K., Fujii T., Ishiwata T., Yamamoto T., Kawamoto Y., Kawahara K., Nakazawa N., Naito Z., Keratinocyte growth factor induces vascular endothelial growth factor-A expression in colorectal cancer cells. International Journal of Oncology 2009 34 2 355 360 2-s2.0-64549087241 10.3892/ijo00000158
    • (2009) International Journal of Oncology , vol.34 , Issue.2 , pp. 355-360
    • Narita, K.1    Fujii, T.2    Ishiwata, T.3    Yamamoto, T.4    Kawamoto, Y.5    Kawahara, K.6    Nakazawa, N.7    Naito, Z.8
  • 57
    • 36048990837 scopus 로고    scopus 로고
    • Keratinocyte growth factor-transfection-stimulated adhesion of colorectal cancer cells to extracellular matrices
    • DOI 10.1016/j.yexmp.2007.07.001, PII S0014480007000858
    • Kudo M., Ishiwata T., Nakazawa N., Kawahara K., Fujii T., Teduka K., Naito Z., Keratinocyte growth factor-transfection-stimulated adhesion of colorectal cancer cells to extracellular matrices. Experimental and Molecular Pathology 2007 83 3 443 452 2-s2.0-36048990837 10.1016/j.yexmp.2007.07.001 (Pubitemid 350087022)
    • (2007) Experimental and Molecular Pathology , vol.83 , Issue.3 , pp. 443-452
    • Kudo, M.1    Ishiwata, T.2    Nakazawa, N.3    Kawahara, K.4    Fujii, T.5    Teduka, K.6    Naito, Z.7
  • 58
    • 84860255645 scopus 로고    scopus 로고
    • Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation
    • Ishiwata T., Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation. American Journal of Pathology 2012 180 5 1928 1941
    • (2012) American Journal of Pathology , vol.180 , Issue.5 , pp. 1928-1941
    • Ishiwata, T.1
  • 59
    • 78650231488 scopus 로고    scopus 로고
    • Significance of keratinocyte growth factor receptor in the proliferation of biliary tract cancer
    • 2-s2.0-78650231488
    • Amano R., Yamada N., Doi Y., Yashiro M., Ohira M., Miwa A., Hirakawa K., Significance of keratinocyte growth factor receptor in the proliferation of biliary tract cancer. Anticancer Research 2010 30 10 4115 4121 2-s2.0-78650231488
    • (2010) Anticancer Research , vol.30 , Issue.10 , pp. 4115-4121
    • Amano, R.1    Yamada, N.2    Doi, Y.3    Yashiro, M.4    Ohira, M.5    Miwa, A.6    Hirakawa, K.7
  • 60
    • 33750701827 scopus 로고    scopus 로고
    • A Novel Molecular Targeting Compound as K-samII/FGF-R2 Phosphorylation Inhibitor, Ki23057, for Scirrhous Gastric Cancer
    • DOI 10.1053/j.gastro.2006.08.030, PII S0016508506017896
    • Nakamura K., Yashiro M., Matsuoka T., Tendo M., Shimizu T., Miwa A., Hirakawa K., A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for scirrhous gastric cancer. Gastroenterology 2006 131 5 1530 1541 2-s2.0-33750701827 10.1053/j.gastro.2006. 08.030 (Pubitemid 44708935)
    • (2006) Gastroenterology , vol.131 , Issue.5 , pp. 1530-1541
    • Nakamura, K.1    Yashiro, M.2    Matsuoka, T.3    Tendo, M.4    Shimizu, T.5    Miwa, A.6    Hirakawa, K.7
  • 62
    • 36049046092 scopus 로고    scopus 로고
    • A novel angiogenesis inhibitor, Ki23057, is useful for preventing the progression of colon cancer and the spreading of cancer cells to the liver
    • DOI 10.1016/j.ejca.2007.09.002, PII S0959804907007009
    • Sakurai K., Yamada N., Yashiro M., Matsuzaki T., Komatsu M., Ohira M., Miwa A., Hirakawa K., A novel angiogenesis inhibitor, Ki23057, is useful for preventing the progression of colon cancer and the spreading of cancer cells to the liver. European Journal of Cancer 2007 43 17 2612 2620 2-s2.0-36049046092 10.1016/j.ejca.2007.09.002 (Pubitemid 350086941)
    • (2007) European Journal of Cancer , vol.43 , Issue.17 , pp. 2612-2620
    • Sakurai, K.1    Yamada, N.2    Yashiro, M.3    Matsuzaki, T.4    Komatsu, M.5    Ohira, M.6    Miwa, A.7    Hirakawa, K.8
  • 63
    • 78650331674 scopus 로고    scopus 로고
    • Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts
    • 2-s2.0-78650331674 10.1158/1078-0432.CCR-10-0531
    • Zhao W. M., Wang L., Park H., Chhim S., Tanphanich M., Yashiro M., Kim K. J., Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts. Clinical Cancer Research 2010 16 23 5750 5758 2-s2.0-78650331674 10.1158/1078-0432.CCR-10-0531
    • (2010) Clinical Cancer Research , vol.16 , Issue.23 , pp. 5750-5758
    • Zhao, W.M.1    Wang, L.2    Park, H.3    Chhim, S.4    Tanphanich, M.5    Yashiro, M.6    Kim, K.J.7
  • 64
    • 80052741228 scopus 로고    scopus 로고
    • Antitumor activity of a recombinant soluble ectodomain of mutant human fibroblast growth factor receptor-2 IIIc
    • Wang J., Antitumor activity of a recombinant soluble ectodomain of mutant human fibroblast growth factor receptor-2 IIIc. Molecular Cancer Therapeutics 2011 10 9 1656 1666
    • (2011) Molecular Cancer Therapeutics , vol.10 , Issue.9 , pp. 1656-1666
    • Wang, J.1
  • 65
    • 0030070238 scopus 로고    scopus 로고
    • Distribution of fibroblast growth factor (FGF)-2 and FGF receptor-1 messenger RNA expression and protein presence in the mid-trimester human fetus
    • Gonzalez A. M., Hill D. J., Logan A., Maher P. A., Baird A., Distribution of fibroblast growth factor (FGF)-2 and FGF receptor-1 messenger RNA expression and protein presence in the mid-trimester human fetus. Pediatric Research 1996 39 3 375 385 2-s2.0-0030070238 (Pubitemid 26070827)
    • (1996) Pediatric Research , vol.39 , Issue.3 , pp. 375-385
    • Gonzalez, A.M.1    Hill, D.J.2    Logan, A.3    Maher, P.A.4    Baird, A.5
  • 68
    • 0033900046 scopus 로고    scopus 로고
    • Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer
    • Jang J. H., Shin K. H., Park Y. J., Lee R. J., McKeehan W. L., Park J. G., Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer. Cancer Research 2000 60 15 4049 4052 2-s2.0-0033900046 (Pubitemid 30636582)
    • (2000) Cancer Research , vol.60 , Issue.15 , pp. 4049-4052
    • Jang, J.-H.1    Shin, K.-H.2    Park, Y.-J.3    Lee, R.J.4    McKeehan, W.L.5    Park, J.-G.6
  • 70
    • 0034685038 scopus 로고    scopus 로고
    • Identification of a novel alternative splicing of human FGF receptor 4: Soluble-form splice variant expressed in human gastrointestinal epithelial cells
    • DOI 10.1006/bbrc.1999.2010
    • Takaishi S., Sawada M., Morita Y., Seno H., Fukuzawa H., Chiba T., Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochemical and Biophysical Research Communications 2000 267 2 658 662 2-s2.0-0034685038 10.1006/bbrc.1999.2010 (Pubitemid 30076854)
    • (2000) Biochemical and Biophysical Research Communications , vol.267 , Issue.2 , pp. 658-662
    • Takaishi, S.1    Sawada, M.2    Morita, Y.3    Seno, H.4    Fukuzawa, H.5    Chiba, T.6
  • 71
    • 1642323740 scopus 로고    scopus 로고
    • Protein Kinase Inhibitors: Insights into Drug Design from Structure
    • DOI 10.1126/science.1095920
    • Noble M. E. M., Endicott J. A., Johnson L. N., Protein kinase inhibitors: insights into drug design from structure. Science 2004 303 5665 1800 1805 2-s2.0-1642323740 10.1126/science.1095920 (Pubitemid 38374863)
    • (2004) Science , vol.303 , Issue.5665 , pp. 1800-1805
    • Noble, M.E.M.1    Endicott, J.A.2    Johnson, L.N.3
  • 72
    • 22044442973 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • DOI 10.1056/NEJMra044389
    • Krause D. S., Van Etten R. A., Tyrosine kinases as targets for cancer therapy. New England Journal of Medicine 2005 353 2 172 187 2-s2.0-22044442973 10.1056/NEJMra044389 (Pubitemid 41058349)
    • (2005) New England Journal of Medicine , vol.353 , Issue.2 , pp. 172-187
    • Krause, D.S.1    Van Etten, R.A.2
  • 73
    • 33645961885 scopus 로고    scopus 로고
    • Bioinformatics for cancer management in the post-genome era
    • 2-s2.0-33645961885
    • Katoh M., Katoh M., Bioinformatics for cancer management in the post-genome era. Technology in Cancer Research and Treatment 2006 5 2 169 175 2-s2.0-33645961885
    • (2006) Technology in Cancer Research and Treatment , vol.5 , Issue.2 , pp. 169-175
    • Katoh, M.1    Katoh, M.2
  • 74
    • 34250625645 scopus 로고    scopus 로고
    • Synergistic anti-tumor effect of recombinant chicken fibroblast growth receptor-1-mediated anti-angiogenesis and low-dose gemcitabine in a mouse colon adenocarcinoma model
    • 2-s2.0-34250625645
    • Zheng S. J., Zheng S. P., Huang F. Y., Jiao C. L., Wu R. L., Synergistic anti-tumor effect of recombinant chicken fibroblast growth receptor-1-mediated anti-angiogenesis and low-dose gemcitabine in a mouse colon adenocarcinoma model. World Journal of Gastroenterology 2007 13 17 2484 2489 2-s2.0-34250625645
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.17 , pp. 2484-2489
    • Zheng, S.J.1    Zheng, S.P.2    Huang, F.Y.3    Jiao, C.L.4    Wu, R.L.5
  • 75
    • 72949117051 scopus 로고    scopus 로고
    • TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model
    • 2-s2.0-72949117051 10.1007/s00595-009-4020-y
    • Ohta M., Kawabata T., Yamamoto M., Tanaka T., Kikuchi H., Hiramatsu Y., Kamiya K., Baba M., Konno H., TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model. Surgery Today 2009 39 12 1046 1053 2-s2.0-72949117051 10.1007/s00595-009-4020-y
    • (2009) Surgery Today , vol.39 , Issue.12 , pp. 1046-1053
    • Ohta, M.1    Kawabata, T.2    Yamamoto, M.3    Tanaka, T.4    Kikuchi, H.5    Hiramatsu, Y.6    Kamiya, K.7    Baba, M.8    Konno, H.9
  • 76
    • 34547100778 scopus 로고    scopus 로고
    • Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist
    • DOI 10.1158/0008-5472.CAN-06-4555
    • Ayers M., Fargnoli J., Lewin A., Wu Q., Suso Platero J., Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist. Cancer Research 2007 67 14 6899 6906 2-s2.0-34547100778 10.1158/0008-5472.CAN-06-4555 (Pubitemid 47105537)
    • (2007) Cancer Research , vol.67 , Issue.14 , pp. 6899-6906
    • Ayers, M.1    Fargnoli, J.2    Lewin, A.3    Wu, Q.4    Suso Platero, J.5
  • 77
    • 77953116873 scopus 로고    scopus 로고
    • Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models
    • 2-s2.0-77953116873 10.1158/1078-0432.CCR-10-0325
    • Tentler J. J., Bradshaw-Pierce E. L., Serkova N. J., Hasebroock K. M., Pitts T. M., Diamond J. R., Fletcher G. C., Bray M. R., Eckhardt S. G., Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models. Clinical Cancer Research 2010 16 11 2989 2998 2-s2.0-77953116873 10.1158/1078-0432.CCR-10-0325
    • (2010) Clinical Cancer Research , vol.16 , Issue.11 , pp. 2989-2998
    • Tentler, J.J.1    Bradshaw-Pierce, E.L.2    Serkova, N.J.3    Hasebroock, K.M.4    Pitts, T.M.5    Diamond, J.R.6    Fletcher, G.C.7    Bray, M.R.8    Eckhardt, S.G.9
  • 79
    • 42249103255 scopus 로고    scopus 로고
    • Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis
    • DOI 10.1158/1535-7163.MCT-07-0394
    • Martínez-Torrecuadrada J. L., Cheung L. H., López-Serra P., Barderas R., Caamero M., Ferreiro S., Rosenblum M. G., Casal J. I., Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis. Molecular Cancer Therapeutics 2008 7 4 862 873 2-s2.0-42249103255 10.1158/1535-7163.MCT- 07-0394 (Pubitemid 351551039)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.4 , pp. 862-873
    • Martinez-Torrecuadrada, J.L.1    Cheung, L.H.2    Lopez-Serra, P.3    Barderas, R.4    Canamero, M.5    Ferreiro, S.6    Rosenblum, M.G.7    Casal, J.I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.