-
1
-
-
0032772374
-
Surgery followed by radiotherapy in endometrial cancer: Analysis of survival and patterns of failure
-
Jereczek-Fossa B, Badzio A, Jassem J: Surgery followed by radiotherapy in endometrial cancer: analysis of survival and patterns of failure. Int J. Gynecol. Cancer 9, 285-294 (1999).
-
(1999)
Int J. Gynecol. Cancer
, vol.9
, pp. 285-294
-
-
Jereczek-Fossa, B.1
Badzio, A.2
Jassem, J.3
-
2
-
-
18144432776
-
Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: Multicentre randomised trial. PORTEC Study Group. Post operative radiation therapy in endometrial carcinoma
-
Creutzberg CL, van Putten WL, Koper PC et al.: Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post operative radiation therapy in endometrial carcinoma. Lancet 355, 1404-1411 (2000)
-
(2000)
Lancet
, vol.355
, pp. 1404-1411
-
-
Creutzberg, C.L.1
van Putten, W.L.2
Koper, P.C.3
-
3
-
-
33744493376
-
Targeting tyrosine kinases in cancer the second wave
-
Baselga J: Targeting tyrosine kinases in cancer the second wave. Science 312, 1175-1178 (2006).
-
(2006)
Science
, vol.312
, pp. 1175-1178
-
-
Baselga, J.1
-
4
-
-
34250829395
-
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
-
Pollock PM, Gartside MG, Dejeza LC et al.: Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Oncogene 26, 7158-7162 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 7158-7162
-
-
Pollock, P.M.1
Gartside, M.G.2
Dejeza, L.C.3
-
5
-
-
47249122523
-
Drug-sensitive FGFR2 mutations in endometrial carcinoma
-
Dutt A, Salvesen HB, Chen TH et al.: Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc. Natl Acad. Sci. USA 105, 8713-8717 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 8713-8717
-
-
Dutt, A.1
Salvesen, H.B.2
Chen, T.H.3
-
6
-
-
0035081241
-
Fibroblast growth factors
-
23, REVIEWS3005
-
Ornitz DM, Itoh N: Fibroblast growth factors. Genome Biol. 2(3), REVIEWS3005 (2001).
-
(2001)
Genome Biol
-
-
Ornitz, D.M.1
Itoh, N.2
-
8
-
-
0037108225
-
FGFs, their receptors, and human limb malformations: Clinical and molecular correlations
-
Wilkie AO, Patey SJ, Kan SH, van den Ouweland AM, Hamel BC: FGFs, their receptors, and human limb malformations: clinical and molecular correlations. Am. J. Med. Genet. 112, 266-278 (2002).
-
(2002)
Am. J. Med. Genet
, vol.112
, pp. 266-278
-
-
Wilkie, A.O.1
Patey, S.J.2
Kan, S.H.3
van den Ouweland, A.M.4
Hamel, B.C.5
-
9
-
-
0034687699
-
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome
-
Yu K, Herr AB, Waksman G, Ornitz DM: Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc. Natl. Acad. Sci. USA 97,14536-14541 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14536-14541
-
-
Yu, K.1
Herr, A.B.2
Waksman, G.3
Ornitz, D.M.4
-
10
-
-
0025970826
-
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop
-
Miki T, Fleming TP, Bottaro DP, Rubin JS, Ron D, Aaronson SA: Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science 251, 72-75 (1991).
-
(1991)
Science
, vol.251
, pp. 72-75
-
-
Miki, T.1
Fleming, T.P.2
Bottaro, D.P.3
Rubin, J.S.4
Ron, D.5
Aaronson, S.A.6
-
11
-
-
34548250374
-
A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases
-
Chen H, Ma J, Li W et al.: A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol. Cell 27, 717-730 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 717-730
-
-
Chen, H.1
Ma, J.2
Li, W.3
-
12
-
-
33750576103
-
Molecular and pathologic aspects of endometrial carcinogenesis
-
Hecht JL, Mutter GL: Molecular and pathologic aspects of endometrial carcinogenesis. J. Clin. Oncol. 24, 4783-4791 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4783-4791
-
-
Hecht, J.L.1
Mutter, G.L.2
-
13
-
-
33644625424
-
Early endometrial carcinoma: Clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment
-
Shiozawa T, Konishi I: Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment. Int. J. Clin. Oncol. 11, 13-21 (2006).
-
(2006)
Int. J. Clin. Oncol
, vol.11
, pp. 13-21
-
-
Shiozawa, T.1
Konishi, I.2
-
14
-
-
33644848579
-
Uterine papillary serous and clear cell carcinomas predict for poorer survival compared with grade 3 endometrioid corpus cancers
-
Hamilton CA, Cheung MK, Osann K et al.: Uterine papillary serous and clear cell carcinomas predict for poorer survival compared with grade 3 endometrioid corpus cancers. Br. J. Cancer 94, 642-646 (2006).
-
(2006)
Br. J. Cancer
, vol.94
, pp. 642-646
-
-
Hamilton, C.A.1
Cheung, M.K.2
Osann, K.3
-
15
-
-
52049086201
-
Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
-
Byron SA, Gartside MG, Wellens CL et al.: Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation, Cancer Res. 68, 6902-6907 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 6902-6907
-
-
Byron, S.A.1
Gartside, M.G.2
Wellens, C.L.3
-
16
-
-
0037457660
-
Imatinib inhibits various types of activating mutant kit found in gastrointestinal stromal tumors
-
Chen H, Isozaki K, Kinoshita K et al.: Imatinib inhibits various types of activating mutant kit found in gastrointestinal stromal tumors. Int. J. Cancer 105, 130-135 (2003).
-
(2003)
Int. J. Cancer
, vol.105
, pp. 130-135
-
-
Chen, H.1
Isozaki, K.2
Kinoshita, K.3
-
17
-
-
40249100997
-
Resistance to imatinib mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation
-
Montiel-Duarte C, Cordeu L, Agirre X et al.: Resistance to imatinib mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation. Leuk. Res. 32(5), 709-716 (2007).
-
(2007)
Leuk. Res
, vol.32
, Issue.5
, pp. 709-716
-
-
Montiel-Duarte, C.1
Cordeu, L.2
Agirre, X.3
-
18
-
-
34250209144
-
Consequences of the loss of p53, RB1, and PTEN: Relationship to gefitinib resistance in endometrial cancer
-
Albitar L, Carter MB, Davies S, Leslie KK: Consequences of the loss of p53, RB1, and PTEN: relationship to gefitinib resistance in endometrial cancer. Gynecol. Oncol. 106, 94-104 (2007).
-
(2007)
Gynecol. Oncol
, vol.106
, pp. 94-104
-
-
Albitar, L.1
Carter, M.B.2
Davies, S.3
Leslie, K.K.4
-
19
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan HK, Zhou X et al.: PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6, 117-127 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, H.K.2
Zhou, X.3
-
20
-
-
21044443128
-
In vivo target modulation and biological activity of CHIR-258, a multitargeted growth factor receptor kinase inhibitor, in colon cancer models
-
Lee SH, Lopes de Menezes D, Vora J et al.: In vivo target modulation and biological activity of CHIR-258, a multitargeted growth factor receptor kinase inhibitor, in colon cancer models. Clin. Cancer Res. 11, 3633-3641 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 3633-3641
-
-
Lee, S.H.1
Lopes de Menezes, D.2
Vora, J.3
-
21
-
-
42249087301
-
A Phase I pharmacokinetic and pharmacodynamic study of TKI258, an oral, multitargeted receptor tyrosine kinase inhibitor in patients with advanced solid tumors
-
Sarker D, Molife R, Evans TR et al.: A Phase I pharmacokinetic and pharmacodynamic study of TKI258, an oral, multitargeted receptor tyrosine kinase inhibitor in patients with advanced solid tumors. Clin. Cancer Res. 14, 2075-2081 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 2075-2081
-
-
Sarker, D.1
Molife, R.2
Evans, T.R.3
-
22
-
-
34249783442
-
AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor
-
Takeda M, Arao T, Yokote H et al.: AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor. Clin. Cancer Res. 13, 3051-3057 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 3051-3057
-
-
Takeda, M.1
Arao, T.2
Yokote, H.3
-
23
-
-
66949179467
-
-
Rosen LS, Wilding G, Sweeney C et al.: Phase I dose escalation study to determine the safety, pharmacokinetics and pharmacodynamics of BMS-582664, a VEGFR/FGFR inhibitor in patients with advanced/metastatic solid tumors. J. Clin. Oncol. 2006 ASCO Annual Meeting Proceedings Part I. 24(18S), 3051 (2006).
-
Rosen LS, Wilding G, Sweeney C et al.: Phase I dose escalation study to determine the safety, pharmacokinetics and pharmacodynamics of BMS-582664, a VEGFR/FGFR inhibitor in patients with advanced/metastatic solid tumors. J. Clin. Oncol. 2006 ASCO Annual Meeting Proceedings Part I. 24(18S), 3051 (2006).
-
-
-
-
24
-
-
37549071104
-
PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
-
Carpinelli P, Ceruti R, Giorgini ML et al.: PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer. Mol. Cancer Ther. 6, 3158-3168 (2007).
-
(2007)
Mol. Cancer Ther
, vol.6
, pp. 3158-3168
-
-
Carpinelli, P.1
Ceruti, R.2
Giorgini, M.L.3
-
25
-
-
47949108203
-
Aurora kinases and their inhibitors: More than one target and one drug
-
Carpinelli P, Moll J: Aurora kinases and their inhibitors: more than one target and one drug. Adv. Exp. Med. Biol. 610, 54-73 (2008).
-
(2008)
Adv. Exp. Med. Biol
, vol.610
, pp. 54-73
-
-
Carpinelli, P.1
Moll, J.2
-
26
-
-
49649123154
-
BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
-
Hilberg F, Roth GJ, Krssak M et al.: BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res. 68, 4774-4782 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 4774-4782
-
-
Hilberg, F.1
Roth, G.J.2
Krssak, M.3
|