-
1
-
-
24144453087
-
Microglia and inflammationmediated neurodegeneration: Multiple triggers with a common mechanism
-
Block ML, Hong JS (2005) Microglia and inflammationmediated neurodegeneration: Multiple triggers with a common mechanism. Prog Neurobiol 76, 77-98.
-
(2005)
Prog Neurobiol
, vol.76
, pp. 77-98
-
-
Block, M.L.1
Hong, J.S.2
-
2
-
-
34547253128
-
Biochemical aspects of inflammation
-
Kulinsky VI (2007) Biochemical aspects of inflammation. Biochem Moscow 72, 595-607.
-
(2007)
Biochem Moscow
, vol.72
, pp. 595-607
-
-
Kulinsky, V.I.1
-
3
-
-
11444256801
-
Glia and their cytokines in progression of neurodegeneration
-
Mrak RE, Griffin ST (2005) Glia and their cytokines in progression of neurodegeneration. Neurobiol Aging 26, 349-354.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 349-354
-
-
Mrak, R.E.1
Griffin, S.T.2
-
4
-
-
33748471099
-
Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
-
Wyss-Coray T (2006) Inflammation in Alzheimer disease: Driving force, bystander or beneficial response? Nat Med 12, 1005-1015.
-
(2006)
Nat Med
, vol.12
, pp. 1005-1015
-
-
Wyss-Coray, T.1
-
5
-
-
72449204160
-
Does neuroinflammation fan the flame in neurodegenerative diseases?
-
Frank-Cannon TC, Alto LT, McAlpine FE, TanseyMG(2009) Does neuroinflammation fan the flame in neurodegenerative diseases? Mol Neurodegener 4, 47-59.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 47-59
-
-
Frank-Cannon, T.C.1
Alto, L.T.2
McAlpine, F.E.3
Tansey, M.G.4
-
6
-
-
47749126515
-
Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression
-
Gao HM, Hong JS (2008) Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression. Trends Immunol 29, 357-365.
-
(2008)
Trends Immunol
, vol.29
, pp. 357-365
-
-
Gao, H.M.1
Hong, J.S.2
-
7
-
-
41749116202
-
Glial cell dysregulation: A new perspective on Alzheimer disease
-
von Bernhardi R (2007) Glial cell dysregulation: A new perspective on Alzheimer disease. Neurotox Res 12, 215-232.
-
(2007)
Neurotox Res
, vol.12
, pp. 215-232
-
-
Von Bernhardi, R.1
-
8
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass CK, Saijo K,Winner B, MarchettoMC,GageFH(2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
9
-
-
75949127404
-
Agingdependent changes of microglial cells and their relevance for neurodegenerative disorders
-
von Bernhardi R, Tichauer J, Eugen'in J (2010) Agingdependent changes of microglial cells and their relevance for neurodegenerative disorders. J Neurochem 112, 1099-1114.
-
(2010)
J Neurochem
, vol.112
, pp. 1099-1114
-
-
Von Bernhardi, R.1
Tichauer, J.2
Eugen'In, J.3
-
10
-
-
77956961694
-
Neuroinflammatory processes in Alzheimer's disease
-
Heneka MT, O'Banion MK, Terwel D, Kummer MP (2010) Neuroinflammatory processes in Alzheimer's disease. J Neural Transm 117, 919-947.
-
(2010)
J Neural Transm
, vol.117
, pp. 919-947
-
-
Heneka, M.T.1
O'Banion, M.K.2
Terwel, D.3
Kummer, M.P.4
-
11
-
-
34547252566
-
Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: Function-based and target-based discovery approaches
-
Van Eldik LJ, Thompson WL, Ralay Ranaivo H, Behanna HA, Watterson DM (2007) Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: Function-based and target-based discovery approaches. Int Rev Neurobiol 82, 277-296.
-
(2007)
Int Rev Neurobiol
, vol.82
, pp. 277-296
-
-
Van Eldik, L.J.1
Thompson, W.L.2
Ralay Ranaivo, H.3
Behanna, H.A.4
Watterson, D.M.5
-
12
-
-
0035087703
-
Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration
-
Pei JJ, Braak E, Braak H, Grundke-Iqbal I, Iqbal K, Winblad B, Cowburn RF (2001) Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. J Alzheimers Dis 3, 41-48.
-
(2001)
J Alzheimers Dis
, vol.3
, pp. 41-48
-
-
Pei, J.J.1
Braak, E.2
Braak, H.3
Grundke-Iqbal, I.4
Iqbal, K.5
Winblad, B.6
Cowburn, R.F.7
-
13
-
-
0141672049
-
P38 MAP kinase is activated at early stages in Alzheimer's disease brain
-
Sun A, Liu M, Nguyen XV, Bing G (2003) P38 MAP kinase is activated at early stages in Alzheimer's disease brain. Exp Neurol 183, 394-405.
-
(2003)
Exp Neurol
, vol.183
, pp. 394-405
-
-
Sun, A.1
Liu, M.2
Nguyen, X.V.3
Bing, G.4
-
14
-
-
14044270858
-
Evidence that phosphorylation of the microtubuleassociated protein Tau by SAPK4/p38d at Thr50 promotes microtubule assembly
-
Feijoo C, Campbell DG, Jakes R, Goedert M, Cuenda A (2005) Evidence that phosphorylation of the microtubuleassociated protein Tau by SAPK4/p38d at Thr50 promotes microtubule assembly. J Cell Sci 118, 397-408.
-
(2005)
J Cell Sci
, vol.118
, pp. 397-408
-
-
Feijoo, C.1
Campbell, D.G.2
Jakes, R.3
Goedert, M.4
Cuenda, A.5
-
15
-
-
33646198145
-
Tau therapeutic strategies for the treatment of Alzheimer's disease
-
Churcher I (2006) Tau therapeutic strategies for the treatment of Alzheimer's disease. Curr Top Med Chem 6, 579-595.
-
(2006)
Curr Top Med Chem
, vol.6
, pp. 579-595
-
-
Churcher, I.1
-
16
-
-
26244465743
-
P38 activation mediates amyloid-beta cytotoxicity
-
Zhu X, Mei M, Lee HG, Wang Y, Han J, Perry G, Smith MA (2005) P38 activation mediates amyloid-beta cytotoxicity. Neurochem Res 30, 791-796.
-
(2005)
Neurochem Res
, vol.30
, pp. 791-796
-
-
Zhu, X.1
Mei, M.2
Lee, H.G.3
Wang, Y.4
Han, J.5
Perry, G.6
Smith, M.A.7
-
17
-
-
33745807628
-
Regulation of inducible nitric oxide synthase gene in glial cells
-
Saha RN, Jana M, Pahan K (2006) Regulation of inducible nitric oxide synthase gene in glial cells. Antioxid Redox Signal 8, 929-947.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 929-947
-
-
Saha, R.N.1
Jana, M.2
Pahan, K.3
-
18
-
-
73449131129
-
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
-
Munoz L, Ammit AJ (2010) Targeting p38 MAPK pathway for the treatment of Alzheimer's disease. Neuropharmacology 58, 561-568.
-
(2010)
Neuropharmacology
, vol.58
, pp. 561-568
-
-
Munoz, L.1
Ammit, A.J.2
-
19
-
-
0026461349
-
Genomic structure, induction, and production of TNF
-
Spriggs DR, Deutsch S, Kufe DW(1992) Genomic structure, induction, and production of TNF-. Immunol Ser 56, 3-34.
-
(1992)
Immunol ser
, vol.56
, pp. 3-34
-
-
Spriggs, D.R.1
Deutsch, S.2
Kufe, D.W.3
-
20
-
-
3142546235
-
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway mediated Mrna stabilization
-
Dean JL, Sully G, Clark AR, Saklatvala J (2004) The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway mediated Mrna stabilization. Cell Signal 16, 1113-1121.
-
(2004)
Cell Signal
, vol.16
, pp. 1113-1121
-
-
Dean, J.L.1
Sully, G.2
Clark, A.R.3
Saklatvala, J.4
-
21
-
-
33847176551
-
MAPK phosphatases - Regulating the immune response
-
Liu Y, Shepherd EG, Nelin LD (2007) MAPK phosphatases - regulating the immune response. Nat Rev Immunol 7, 202- 212.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 202-212
-
-
Liu, Y.1
Shepherd, E.G.2
Nelin, L.D.3
-
22
-
-
54049141728
-
Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death and cancer
-
Boutros T, Chevet E, Metrakos P (2008) Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death and cancer. Pharmacol Rev 60, 261-310.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 261-310
-
-
Boutros, T.1
Chevet, E.2
Metrakos, P.3
-
23
-
-
29544446576
-
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells
-
Eljaschewitsch E,Witting A, Mawrin C, Lee T, Schmidt PM, Wolf S, Hoertnagl H, Raine CS, Schneider-Stock R, Nitsch R, Ullrich O (2006) The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 49, 67-79.
-
(2006)
Neuron
, vol.49
, pp. 67-79
-
-
Eljaschewitsch, E.1
Witting, A.2
Mawrin, C.3
Lee, T.4
Schmidt, P.M.5
Wolf, S.6
Hoertnagl, H.7
Raine, C.S.8
Schneider-Stock, R.9
Nitsch, R.10
Ullrich, O.11
-
24
-
-
58849101326
-
The 15-deoxy-d12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFNgamma stimulated astrocytes through induction of MAPK Phosphatase-1
-
Lee JH, Woo JH, Woo SU, Kim KS, Park SM, Joe E, Jou I (2008) The 15-deoxy-d12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFNgamma stimulated astrocytes through induction of MAPK Phosphatase-1. J Immunol 181, 8642-8649.
-
(2008)
J Immunol
, vol.181
, pp. 8642-8649
-
-
Lee, J.H.1
Woo, J.H.2
Woo, S.U.3
Kim, K.S.4
Park, S.M.5
Joe, E.6
Jou, I.7
-
25
-
-
36448936383
-
TGF-SMAD signal transduction: Molecular specificity and functional flexibility
-
Schmierer B, Hill CS (2007) TGF-SMAD signal transduction: Molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 8, 970-982.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
27
-
-
0029140838
-
Cytokine modulation of murine microglial cell superoxide production
-
Hu S, Sheng WS, Peterson PK, Chao CC (1995) Cytokine modulation of murine microglial cell superoxide production. Glia 13, 45-50.
-
(1995)
Glia
, vol.13
, pp. 45-50
-
-
Hu, S.1
Sheng, W.S.2
Peterson, P.K.3
Chao, C.C.4
-
28
-
-
0037209850
-
Inhibition of LPSinduced iNOS and NO synthesis in primary rat microglial cells
-
Lieb K, Engels S, Fiebich BL (2003) Inhibition of LPSinduced iNOS and NO synthesis in primary rat microglial cells. Neurochem Int 42, 131-137.
-
(2003)
Neurochem Int
, vol.42
, pp. 131-137
-
-
Lieb, K.1
Engels, S.2
Fiebich, B.L.3
-
29
-
-
17444363424
-
Transforming growth factor-1 produced by hippocampal cells modulates microglial reactivity in culture
-
Herrera-Molina R, von Bernhardi R (2005) Transforming growth factor-1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiol Dis 19, 229-236.
-
(2005)
Neurobiol Dis
, vol.19
, pp. 229-236
-
-
Herrera-Molina, R.1
Von Bernhardi, R.2
-
30
-
-
9044243405
-
Protective effect of transforming growth factor-1 on -amyloid neurotoxicity in rat hippocampal neurons
-
Prehn JH, Bindokas VP, Jordan J (1996) Protective effect of transforming growth factor-1 on -amyloid neurotoxicity in rat hippocampal neurons. Mol Pharmacol 49, 319-328.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 319-328
-
-
Prehn, J.H.1
Bindokas, V.P.2
Jordan, J.3
-
31
-
-
43049116103
-
TGF-1 protects against A-neurotoxicity via the phosphatidylinositol-3- kinase pathway
-
Caraci F, Battaglia G, Busceti C (2008) TGF-1 protects against A-neurotoxicity via the phosphatidylinositol-3- kinase pathway. Neurobiol Dis 30, 234-242.
-
(2008)
Neurobiol Dis
, vol.30
, pp. 234-242
-
-
Caraci, F.1
Battaglia, G.2
Busceti, C.3
-
32
-
-
0034744296
-
TGF-1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
-
Wyss-Coray T, Lin C, Yan F (2001) TGF-1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med 7, 612-618.
-
(2001)
Nat Med
, vol.7
, pp. 612-618
-
-
Wyss-Coray, T.1
Lin, C.2
Yan, F.3
-
33
-
-
0034711282
-
Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3
-
Werner F, Jain MK, Feinberg MW, Sibinga NE, Pellacani A, Wiesel P, Chin MT, Topper JN, Perrella MA, Lee ME (2000) Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3. J Biol Chem 275, 36653- 36658.
-
(2000)
J Biol Chem
, vol.275
, pp. 36653-36658
-
-
Werner, F.1
Jain, M.K.2
Feinberg, M.W.3
Sibinga, N.E.4
Pellacani, A.5
Wiesel, P.6
Chin, M.T.7
Topper, J.N.8
Perrella, M.A.9
Lee, M.E.10
-
34
-
-
3142729969
-
TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways
-
Le Y, Iribarren P, GongW, Cui Y, Zhang X,Wang JM (2004) TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways. J Immunol 173, 962- 968.
-
(2004)
J Immunol
, vol.173
, pp. 962-968
-
-
Le, Y.1
Iribarren, P.2
Gong, W.3
Cui, Y.4
Zhang, X.5
Wang, J.M.6
-
35
-
-
0036944699
-
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis
-
Docagne F, Nicole O, Gabriel C, Fern'andez-Monreal M, Lesn'e S, Ali C, Plawinski L, Carmeliet P, MacKenzie ET, Buisson A, Vivien D (2002) Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis. Mol Cell Neurosci 21, 634- 644.
-
(2002)
Mol Cell Neurosci
, vol.21
, pp. 634-644
-
-
Docagne, F.1
Nicole, O.2
Gabriel, C.3
Fern'Andez-Monreal, M.4
Lesn'E, S.5
Ali, C.6
Plawinski, L.7
Carmeliet, P.8
MacKenzie, E.T.9
Buisson, A.10
Vivien, D.11
-
36
-
-
84864857755
-
TGF stimulates A uptake by microglia through Smad3-dependent mechanisms
-
Tichauer J, von Bernhardi R (2012) TGF stimulates A uptake by microglia through Smad3-dependent mechanisms. J Neurosci Res 90, 1970-1980.
-
(2012)
J Neurosci Res
, vol.90
, pp. 1970-1980
-
-
Tichauer, J.1
Von Bernhardi, R.2
-
37
-
-
0037010289
-
Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1:Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling
-
Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ (2002) Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1:Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 70, 462-473.
-
(2002)
J Neurosci Res
, vol.70
, pp. 462-473
-
-
Colangelo, V.1
Schurr, J.2
Ball, M.J.3
Pelaez, R.P.4
Bazan, N.G.5
Lukiw, W.J.6
-
38
-
-
17844387606
-
Large-scale microarray studies of gene expression in multiple regions of the brain in schizophrenia and Alzheimer's disease
-
Katsel PL, Davis KL, Haroutunian V (2005) Large-scale microarray studies of gene expression in multiple regions of the brain in schizophrenia and Alzheimer's disease. Int Rev Neurobiol 63, 41-82.
-
(2005)
Int Rev Neurobiol
, vol.63
, pp. 41-82
-
-
Katsel, P.L.1
Davis, K.L.2
Haroutunian, V.3
-
39
-
-
0033876817
-
Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia
-
Luterman JD, Haroutunian V, Yemul S (2000) Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Arch Neurol 57, 1153-1160.
-
(2000)
Arch Neurol
, vol.57
, pp. 1153-1160
-
-
Luterman, J.D.1
Haroutunian, V.2
Yemul, S.3
-
40
-
-
33750591957
-
Deficiency in neuronal TGF- signaling promotes neurodegeneration and Alzheimer's pathology
-
Tesseur I, Zou K, Esposito L (2006) Deficiency in neuronal TGF- signaling promotes neurodegeneration and Alzheimer's pathology. J Clin Invest 116, 3060-3069.
-
(2006)
J Clin Invest
, vol.116
, pp. 3060-3069
-
-
Tesseur, I.1
Zou, K.2
Esposito, L.3
-
41
-
-
33750320547
-
Altered subcellular location of phosphorylated Smads in Alzheimer's disease
-
Ueberham U, Ueberham E, Gruschka H, Arendt T (2006) Altered subcellular location of phosphorylated Smads in Alzheimer's disease. Eur J Neurosci 24, 2327-2334.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 2327-2334
-
-
Ueberham, U.1
Ueberham, E.2
Gruschka, H.3
Arendt, T.4
-
42
-
-
0034604110
-
Role of transforming growth factor in human disease
-
Blobe GC, Schiemann WP, Lodish HF (2000) Role of transforming growth factor in human disease. N Engl J Med 342, 1350-1358.
-
(2000)
N Engl J Med
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
43
-
-
0032080309
-
Stable complexes involving acetylcholinesterase and amyloid- peptide change the biochemicalproperties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils
-
Á lvarez A, Alarcón R, Opazo C, Campos EO, Munoz FJ, Caldeŕon FH, Dajas F, Gentry MK, Doctor BP, De Mello FG, Inestrosa NC (1998) Stable complexes involving acetylcholinesterase and amyloid- peptide change the biochemicalproperties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. J Neurosci 18, 3213-3223.
-
(1998)
J Neurosci
, vol.18
, pp. 3213-3223
-
-
Á, L.A.1
Alarcón, R.2
Opazo, C.3
Campos, E.O.4
Munoz, F.J.5
Caldeŕon, F.H.6
Dajas, F.7
Gentry, M.K.8
Doctor, B.P.9
De Mello, F.G.10
Inestrosa, N.C.11
-
44
-
-
37049017788
-
Modulation by astrocytes of microglial cell-mediated neuroinflammation: Effect on the activation of microglial signaling pathways
-
Tichauer J, Saud K, von Bernhardi R (2007) Modulation by astrocytes of microglial cell-mediated neuroinflammation: Effect on the activation of microglial signaling pathways. Neuroimmunomodulation 14, 168-174.
-
(2007)
Neuroimmunomodulation
, vol.14
, pp. 168-174
-
-
Tichauer, J.1
Saud, K.2
Von Bernhardi, R.3
-
45
-
-
0031023654
-
Metabolic fate of peroxynitrite in aqueous solution
-
Pfeiffer S, Gorren AC, Schmidt K, Werner ER, Hanser B, Bohle DS, Mayer B (1997) Metabolic fate of peroxynitrite in aqueous solution. J Biol Chem 272, 3465-3470.
-
(1997)
J Biol Chem
, vol.272
, pp. 3465-3470
-
-
Pfeiffer, S.1
Gorren, A.C.2
Schmidt, K.3
Werner, E.R.4
Hanser, B.5
Bohle, D.S.6
Mayer, B.7
-
46
-
-
0032510692
-
Amyloid -peptide stimulates nitric oxide production in astrocytes through an NF-κB-dependent mechanism
-
Akama KT, Albanese C, Pestell RG, van Eldik L (1998) Amyloid -peptide stimulates nitric oxide production in astrocytes through an NF-κB- dependent mechanism. Proc Natl Acad Sci U S A 95, 5795-5800.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5795-5800
-
-
Akama, K.T.1
Albanese, C.2
Pestell, R.G.3
Van Eldik, L.4
-
47
-
-
0032473596
-
Amyloid-beta peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release
-
HuJ,AkamaKT, Krafft GA, ChromyBA,Van Eldik LJ (1998) Amyloid-beta peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release. Brain Res 785, 195-206.
-
(1998)
Brain Res
, vol.785
, pp. 195-206
-
-
Hu, J.1
Akama, K.T.2
Krafft, G.A.3
Chromy, B.A.4
Van Eldik, L.J.5
-
48
-
-
0034678024
-
Amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1- and tumor necrosis factor- (TNF)-dependent, and involves a TNF receptor-associated factor- and NFκB-inducing kinase-dependent signaling mechanism
-
Akama KT, Van Eldik LJ (2000) -Amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1- and tumor necrosis factor- (TNF)-dependent, and involves a TNF receptor-associated factor- and NFκB-inducing kinase-dependent signaling mechanism. J Biol Chem 275, 7918-7924.
-
(2000)
J Biol Chem
, vol.275
, pp. 7918-7924
-
-
Akama, K.T.1
Van Eldik, L.J.2
-
49
-
-
58149181978
-
Fibrillar amyloidbeta peptides activate microglia via TLR2: Implications for Alzheimer's disease
-
Jana M, Palencia CA, Pahan K (2008) Fibrillar amyloidbeta peptides activate microglia via TLR2: Implications for Alzheimer's disease. J Immunol 181, 7254-7262.
-
(2008)
J Immunol
, vol.181
, pp. 7254-7262
-
-
Jana, M.1
Palencia, C.A.2
Pahan, K.3
-
50
-
-
0242663968
-
The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNAmethylating agents
-
Hirose Y, Katayama M, Stokoe D, Haas-Kogan DA, Berger MS, Pieper RO (2003) The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNAmethylating agents. Mol Cell Biol 23, 8306-8315.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8306-8315
-
-
Hirose, Y.1
Katayama, M.2
Stokoe, D.3
Haas-Kogan, D.A.4
Berger, M.S.5
Pieper, R.O.6
-
51
-
-
38449119486
-
MAPK p38 regulates transcriptional activity of NF-κB in primary human astrocytes via acetylation of p65
-
Saha RN, Jana M, Pahan K (2007) MAPK p38 regulates transcriptional activity of NF-κB in primary human astrocytes via acetylation of p65. J Immunol 179, 7101-7109.
-
(2007)
J Immunol
, vol.179
, pp. 7101-7109
-
-
Saha, R.N.1
Jana, M.2
Pahan, K.3
-
52
-
-
78651327656
-
Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells
-
Su D, Peng X, Zhu S, Huang Y, Dong Z, Zhang Y, Zhang J, Liang Q, Lu J, Huang B (2011) Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells. Biochem J 433, 333-343.
-
(2011)
Biochem J
, vol.433
, pp. 333-343
-
-
Su, D.1
Peng, X.2
Zhu, S.3
Huang, Y.4
Dong, Z.5
Zhang, Y.6
Zhang, J.7
Liang, Q.8
Lu, J.9
Huang, B.10
-
53
-
-
33645912622
-
Proand anti-inflammatory cytokines regulate the ERK pathways: Implication of the timing for the activation of microglial cells
-
Saud K, Herrera-Molina R, von Bernhardi R (2005) Proand anti-inflammatory cytokines regulate the ERK pathways: Implication of the timing for the activation of microglial cells. Neurotox Res 8, 277-287.
-
(2005)
Neurotox Res
, vol.8
, pp. 277-287
-
-
Saud, K.1
Herrera-Molina, R.2
Von Bernhardi, R.3
-
54
-
-
31044448265
-
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression
-
Jinnin M, Ihn H, Tamaki K (2006) Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol 69, 597-607.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 597-607
-
-
Jinnin, M.1
Ihn, H.2
Tamaki, K.3
-
55
-
-
80053565062
-
Proliferating culture of aged microglia for the study of neurodegenerative diseases
-
von Bernhardi R, Tichauer J, Eugen'in-von Bernhardi L (2011) Proliferating culture of aged microglia for the study of neurodegenerative diseases. J Neurosci Methods 202, 65-69.
-
(2011)
J Neurosci Methods
, vol.202
, pp. 65-69
-
-
Von Bernhardi, R.1
Tichauer, J.2
Eugen'In-Von Bernhardi, L.3
-
56
-
-
5344277492
-
Microglial reactivity to -amyloid is modulated by astrocytes and proinflammatory factors
-
von Bernhardi R, Eugen'in J (2004) Microglial reactivity to -amyloid is modulated by astrocytes and proinflammatory factors. Brain Res 1025, 186-193.
-
(2004)
Brain Res
, vol.1025
, pp. 186-193
-
-
Von Bernhardi, R.1
Eugen'In, J.2
-
57
-
-
0031172065
-
NF-κB: A crucial transcription factor for glial and neuronal cell function
-
O'Neill LA, Kaltschmidt C (1997) NF-κB: A crucial transcription factor for glial and neuronal cell function. Trends Neurosci 20, 252-258.
-
(1997)
Trends Neurosci
, vol.20
, pp. 252-258
-
-
O'Neill, L.A.1
Kaltschmidt, C.2
-
58
-
-
0035375277
-
Amyloid -peptide induces nitric oxide production in rat hippocampus: Association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors
-
Tran MH, Yamada K, Olariu A, Mizuno M, Ren XH, Nabeshima T (2001) Amyloid -peptide induces nitric oxide production in rat hippocampus: Association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors. FASEB J 15, 1407-1409.
-
(2001)
FASEB J
, vol.15
, pp. 1407-1409
-
-
Tran, M.H.1
Yamada, K.2
Olariu, A.3
Mizuno, M.4
Ren, X.H.5
Nabeshima, T.6
-
59
-
-
29144512322
-
Beta-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor
-
Wang Q, Wu J, Rowan MJ, Anwyl R (2005) Beta-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor. Eur J Neurosci 22, 2827-2832.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2827-2832
-
-
Wang, Q.1
Wu, J.2
Rowan, M.J.3
Anwyl, R.4
-
60
-
-
34548316575
-
Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice
-
He P, Zhong Z, Lindholm K, Berning L, Lee W, Lemere C, Staufenbiel M, Li R, Shen Y (2007) Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice. J Cell Biol 178, 829-841.
-
(2007)
J Cell Biol
, vol.178
, pp. 829-841
-
-
He, P.1
Zhong, Z.2
Lindholm, K.3
Berning, L.4
Lee, W.5
Lemere, C.6
Staufenbiel, M.7
Li, R.8
Shen, Y.9
-
61
-
-
34249027009
-
Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: Relevance for the behavioral and synaptic deficits induced by amyloid beta protein
-
Medeiros R, Prediger RD, Passos GF, Pandolfo P, Duarte FS, Franco JL, Dafre AL, Di Giunta G, Figueiredo CP, Takahashi RN, Campos MM, Calixto JB (2007) Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: Relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J Neurosci 27, 5394-5404.
-
(2007)
J Neurosci
, vol.27
, pp. 5394-5404
-
-
Medeiros, R.1
Prediger, R.D.2
Passos, G.F.3
Pandolfo, P.4
Duarte, F.S.5
Franco, J.L.6
Dafre, A.L.7
Di Giunta, G.8
Figueiredo, C.P.9
Takahashi, R.N.10
Campos, M.M.11
Calixto, J.B.12
-
62
-
-
0042847362
-
Transforming growth factor-Smad signaling pathway negatively regulates nontypeable Haemophilus influenzaeinduced MUC5AC mucin transcription via mitogen-activated protein kinase (MAPK) phosphatase-1-dependent inhibition of p38 MAPK
-
Jono H,XuH, Kai H, Lim DJ,KimYS, Feng XH, Li JD (2003) Transforming growth factor-Smad signaling pathway negatively regulates nontypeable Haemophilus influenzaeinduced MUC5AC mucin transcription via mitogen-activated protein kinase (MAPK) phosphatase-1-dependent inhibition of p38 MAPK. J Biol Chem 278, 27811-27819.
-
(2003)
J Biol Chem
, vol.278
, pp. 27811-27819
-
-
Jono, H.1
Xu, H.2
Kai, H.3
Lim, D.J.4
Kim, Y.S.5
Feng, X.H.6
Li, J.D.7
-
63
-
-
36349029242
-
Transforming growth factor-1 impairs Endothelin-1-mediated contraction of brain vessels by inducing Mitogen-activated protein (MAP) kinase phosphatase-1 and inhibiting p38 MAP kinase
-
Tong X, Hamel E (2007) Transforming growth factor-1 impairs Endothelin-1-mediated contraction of brain vessels by inducing Mitogen-activated protein (MAP) kinase phosphatase-1 and inhibiting p38 MAP kinase. Mol Pharmacol 72, 1476-1483.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1476-1483
-
-
Tong, X.1
Hamel, E.2
-
64
-
-
52449104934
-
Proinflammatory stimuli induce microglial cellmediated APP- and A- neurotoxicity in hippocampal cultures
-
Ram'irez G, Rey S, von Bemhardi R (2008) Proinflammatory stimuli induce microglial cellmediated APP- and A- neurotoxicity in hippocampal cultures. J Alzheimers Dis 15, 45-59.
-
(2008)
J Alzheimers Dis
, vol.15
, pp. 45-59
-
-
Ram'Irez, G.1
Rey, S.2
Von Bemhardi, R.3
-
65
-
-
84866256725
-
Modulation of interferon-γ-induced glial cell activation by transforming growth factor 1: A role for STAT1 and MAPK pathways
-
Herrera-Molina R, Flores B, Orellana JA, von Bemhardi R (2012) Modulation of interferon-γ-induced glial cell activation by transforming growth factor 1: A role for STAT1 and MAPK pathways. J Neurochem 123, 113-123.
-
(2012)
J Neurochem
, vol.123
, pp. 113-123
-
-
Herrera-Molina, R.1
Flores, B.2
Orellana, J.A.3
Von Bemhardi, R.4
|