Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo

PLoS Genetics

Volumn 8, Issue 8, 2012, Pages

  Wishart, Thomas M ^a,b   Rooney, Timothy M ^c   Lamont, Douglas J ^d   Wright, Ann K ^a   Morton, A Jennifer ^e   Jackson, Mandy ^a   Freeman, Marc R ^c   Gillingwater, Thomas H ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYISOBUTYRYL COENZYME A HYDROLASE; ALDEHYDE DEHYDROGENASE; BRCA2 PROTEIN; CALBINDIN; CALBINDIN 2; CALCIUM BINDING PROTEIN; CHAPERONE; DNAJ SUBFAMILY B MEMBER 6 PROTEIN; DNAJ SUBFAMILY C MEMBER 5 PROTEIN; HYDROLASE; PROTEIN DNAJ; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 2; RHO KINASE; UNCLASSIFIED DRUG;

ALDHA1 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALB2 GENE; CONTROLLED STUDY; CYTOSKELETON; DNAJC5 GENE; DROSOPHILA; FEMALE; FUNCTIONAL PROTEOMICS; GENE; GENE CLUSTER; GENETIC ANALYSIS; GENETIC STABILITY; HIBCH GENE; HUNTINGTON CHOREA; IN VIVO STUDY; MOLECULAR BIOLOGY; MOLECULAR GENETICS; MOUSE; NERVE DEGENERATION; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PROTEIN FUNCTION; ROCK2 GENE; SPINOCEREBELLAR DEGENERATION; SYNAPSE NEURODEGENERATION; SYNAPTIC TRANSMISSION;

ALDEHYDE DEHYDROGENASE; ANIMALS; AXONS; BRAIN INJURIES; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; DROSOPHILA; DROSOPHILA PROTEINS; HSP40 HEAT-SHOCK PROTEINS; HUNTINGTON DISEASE; MICE; MOLECULAR CHAPERONES; MUTATION; NERVE DEGENERATION; PROTEOMICS; RHO-ASSOCIATED KINASES; SPINOCEREBELLAR ATAXIAS; SYNAPSES; THIOLESTER HYDROLASES; WALLERIAN DEGENERATION;

EID: 84866175104     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002936     Document Type: Article

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