Kinetic analysis of thermal stability of human low density lipoproteins: A model for LDL fusion in atherogenesis

Journal of Lipid Research

Volumn 53, Issue 10, 2012, Pages 2175-2185

  Lu, Mengxiao ^a   Gantz, Donald L ^a   Herscovitz, Haya ^a   Gursky, Olga ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acidic pH; Atherosclerosis; High order reaction; LDL aggregation, fusion, and rupture; LDL subclasses; Lipid lowering therapies; Sigmoidal denaturation kinetics

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN; MONOCLONAL ANTIBODY;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GEL ELECTROPHORESIS; GEL PERMEATION CHROMATOGRAPHY; HUMAN; LIPID ANALYSIS; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; THERMOSTABILITY;

ATHEROSCLEROSIS; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; HOT TEMPERATURE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIPOPROTEINS, LDL; PARTICLE SIZE; PROTEIN DENATURATION; PROTEIN STABILITY;

EID: 84866157631     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M029629     Document Type: Article

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