Differential Stability of High-density Lipoprotein Subclasses: Effects of Particle Size and Protein Composition

Journal of Molecular Biology

Volumn 387, Issue 3, 2009, Pages 628-638

  Gao, Xuan ^a   Yuan, Shujun ^a   Jayaraman, Shobini ^a   Gursky, Olga ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apolipoprotein dissociation; atherosclerosis; kinetic barriers; lipoprotein fusion; reverse cholesterol transport

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN 2; HIGH DENSITY LIPOPROTEIN 3;

ARTICLE; CONTROLLED STUDY; HEART PROTECTION; HUMAN; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN STABILITY; THERMOSTABILITY;

EID: 62049085675     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.02.036     Document Type: Article

References (54)

1. Joy T., and Hegele R.A. Is raising HDL a futile strategy for atheroprotection?. Nature Rev. Drug Discov. 7 (2008) 143-155
2. Scanu A.M., and Edelstein C. HDL: bridging past and present with a look at the future. FASEB J. 22 (2008) 4044-4054
3. Movva R., and Rader D.J. Laboratory assessment of HDL heterogeneity and function. Clin. Chem. 54 (2008) 788-800
4. Rader D.J. Molecular regulation of HDL metabolism and function: implications for novel therapies. J. Clin. Invest. 116 (2006) 3090-3100
5. Nicholls S.J., and Nissen S.E. New targets of high-density lipoprotein therapy. Curr. Opin. Lipidol. 18 (2007) 421-426
6. Fielding C.J., and Fielding P.E. Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36 (1995) 211-228
7. von Eckardstein A., Nofer J.R., and Assman G. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscler. Thromb. Vasc. Biol. 21 (2001) 13-27
8. Rye K.A., Clay M.A., and Barter P.J. Remodelling of high density lipoproteins by plasma factors. Atherosclerosis 145 (1999) 227-238
9. Davidson W.S., and Thompson T.B. The structure of apolipoprotein A-I in high density lipoproteins. J. Biol. Chem. 282 (2007) 22249-22253
10. Malle E., Marsche G., Panzenboeck U., and Sattler W. Myeloperoxidase-mediated oxidation of high-density lipoprotein: Fingerprints of newly recognized potential proatherogenic lipoproteins. Arch. Biochem. Biophys. 445 (2006) 245-255
11. Acton S., Rigotti A., Landschulz K.T., Xu S., Hobbs H.H., and Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 271 (1996) 518-520
12. Cheung M.C., and Albers J.J. Characterization of lipoprotein particles isolated by immunoaffinity chromatography. Particles containing A-I and A-II and particles containing A-I but no A-II. J. Biol. Chem. 259 (1984) 12201-122219
13. Hedrick C.C., and Lusis A.J. Apolipoprotein A-II: a protein in search of a function. Can. J. Cardiol. 10 (1994) 453-459
14. Blanco-Vaca F., Escolà-Gil J.C., Martín-Campos J.M., and Julve J. Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein. J. Lipid Res. 42 (2001) 1727-1739
15. Tailleux A., Duriez P., Fruchart J.C., and Clavey V. Apolipoprotein A-II, HDL metabolism and atherosclerosis. Atherosclerosis 164 (2002) 1-13
16. Pastier D., Dugué S., Boisfer E., Atger V., Tran N.Q., van Tol A., et al. Apolipoprotein A-II/A-I ratio is a key determinant in vivo of HDL concentration and formation of pre-beta HDL containing apolipoprotein A-II. Biochemistry 40 (2001) 12243-12253
17. Birjmohun R.S., Dallinga-Thie G.M., Kuivenhoven J.A., Stroes E.S., Otvos J.D., Wareham N.J., et al. Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation 116 (2007) 2029-2035
18. Winkler K., Hoffmann M.M., Seelhorst U., Wellnitz B., Boehm B.O., Winkelmann B.R., März W., and Scharnagl H. Apolipoprotein A-II is a negative risk indicator for cardiovascular and total mortality: findings from the Ludwigshafen Risk and Cardiovascular Health Study. Clin. Chem. 54 (2008) 1405-1406
19. Calabresi L., Lucchini A., Vecchio G., Sirtori C.R., and Franceschini G. Human apolipoprotein A-II inhibits the formation of pre-beta high density lipoproteins. Biochim. Biophys. Acta 1304 (1996) 32-42
20. Pussinen P.J., Jauhiainen M., and Ehnholm C. ApoA-II/apoA-I molar ratio in the HDL particle influences phospholipid transfer protein-mediated HDL interconversion. J. Lipid Res. 38 (1997) 12-21
21. Rye K.A., Wee K., Curtiss L.K., Bonnet D.J., and Barter P.J. Apolipoprotein A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation. J. Biol. Chem. 278 (2003) 22530-22536
22. Rye K.A., and Barter P.J. Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 421-428
23. Labeur C., Lambert G., Van Cauteren T., Duverger N., Vanloo B., Chambaz J., et al. Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta1 migrating particles and decreases LCAT activation. Atherosclerosis 139 (1998) 351-362
24. Durbin D.M., and Jonas A. The effect of apolipoprotein A-II on the structure and function of apolipoprotein A-I in a homogeneous reconstituted high density lipoprotein particle. J. Biol. Chem. 272 (1997) 31333-31339
25. Lagocki P.A., and Scanu A.M. In vitro modulation of the apolipoprotein composition of high density lipoprotein. Displacement of apolipoprotein A-I from high density lipoprotein by apolipoprotein A-II. J. Biol. Chem. 255 (1980) 3701-3706
26. Gursky O., Ranjana, and Gantz D.L. Complex of human apolipoprotein C-1 with phospholipid: Thermodynamic or kinetic stability?. Biochemistry 41 (2002) 7373-7384
27. Mehta R., Gantz D.L., and Gursky O. Human plasma high-density lipoproteins are stabilized by kinetic factors. J. Mol. Biol. 328 (2003) 183-192
28. Pownall H.J. Remodeling of human plasma lipoproteins by detergent perturbation. Biochemistry 44 (2005) 9714-9722
29. Jayaraman S., Gantz D.L., and Gursky O. Effects of salt on thermal stability of human plasma high-density lipoproteins. Biochemistry 45 (2006) 4620-4628
30. Gursky O. Apolipoprotein structure and dynamics. Curr. Opin. Lipidol. 16 (2005) 287-294
31. Pownall H.J., and Ehnholm C. The unique role of apolipoprotein A-I in HDL remodeling and metabolism. Curr. Opin. Lipidol. 17 (2006) 209-213
32. Jayaraman S., Gantz D.L., and Gursky O. Kinetic stabilization and fusion of apolipoprotein A-2:DMPC disks: comparison with apoA-1 and apoC-1. Biophys. J. 88 (2005) 2907-2918
33. Segrest J.P., Jones M.K., De Loof H., Brouillette C.G., Venkatachalapathi Y.V., and Anantharamaiah G.M. The amphipathic helix in the exchangeable apolipoproteins: A review of secondary structure and function. J. Lipid Res. 33 (1992) 141-166
34. Nichols A.V., Gong E.L., Blanche P.J., Forte T.M., and Anderson D.W. Effects of guanidine hydrochloride on human plasma high density lipoproteins. Biochim. Biophys. Acta 446 (1976) 226-239
35. Tall A.R., Deckelbaum R.J., Small D.M., and Shipley G.G. Thermal behavior of human plasma high density lipoprotein. Biochim. Biophys. Acta 487 (1977) 145-153
36. Swaney J.B., and Palmieri E. Hybrid association between human apolipoproteins A-I and A-II in aqueous solution and in phospholipid recombinants. Biochim. Biophys. Acta 792 (1984) 164-171
37. Boucher J., Ramsamy T.A., Braschi S., Sahoo D., Neville T.A., and Sparks D.L. Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity. J. Lipid Res. 45 (2004) 849-858
38. Reijngoud D.J., and Phillips M.C. Mechanism of dissociation of human apolipoproteins A-I, A-II, and C from complexes with dimyristoylphosphatidylcholine as studied by thermal denaturation. Biochemistry 23 (1984) 726-734
39. Patsch J.R., Karlin J.B., Scott L.W., Smith L.C., and Gotto Jr. A.M. Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia. Proc. Natl Acad. Sci. USA 80 (1983) 1449-1453
40. Miller N.E. Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis. Am. Heart J. 113 (1987) 589-597
41. Skipski V.P., Barclay M., Barclay R.K., Fetzer V.A., Good J.J., and Archibald F.M. Lipid composition of human serum lipoproteins. Biochem. J. 104 (1967) 340-352
42. 3 particles: relevance to antiapoptotic and antioxidative activities. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 1843-1849
43. Catalano G., Duchene E., Julia Z., Le Goff W., Bruckert E., Chapman M.J., and Guerin M. Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects. J. Lipid Res. 49 (2008) 635-643
44. Pownall H.J., Hosken B.D., Gillard B.K., Higgins C.L., Lin H.Y., and Massey J.B. Speciation of human plasma high-density lipoprotein (HDL): HDL stability and apolipoprotein A-I partitioning. Biochemistry 46 (2007) 7449-7459
45. Schumaker V.N., and Puppione D.L. Sequential flotation ultracentrifugation. Methods Enzymol. 128 (1986) 151-170
46. Benjwal S., Verma S., Rohm K.H., and Gursky O. Monitoring protein aggregation during thermal unfolding in circular dichroism experiments. Protein Sci. 15 (2006) 635-639
47. Skipski V.P., Barclay M., Barclay R.K., Fetzer V.A., Good J.J., and Archibald F.M. Lipid composition of human serum lipoproteins. Biochem. J. 104 (1967) 340-352
48. Han M., Gillard B.K., Courtney H.S., Ward K., Rosales C., Khant H., et al. Disruption of human plasma high-density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I. Biochemistry 48 (2009) 1481-1487
49. Guha M., Gantz D.L., and Gursky O. Effects of acyl chain length, unsaturation and pH on thermal stability of model discoidal high-density lipoproteins. J. Lipid Res. 49 (2008) 1752-17461
50. de Beer M.C., Durbin D.M., Cai L., Jonas A., de Beer F.C., and van der Westhuyzen D.R. Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI. J. Lipid Res. 42 (2001) 309-313
51. Thuahnai S.T., Lund-Katz S., Williams D.L., and Phillips M.C. Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor. J. Biol. Chem. 276 (2001) 43801-43808
52. Guha M., Gao X., Jayaraman S., and Gursky O. Correlation of structural stability with functional remodeling of high-density lipoproteins: The importance of being disordered. Biochemistry 47 (2008) 11393-11397
53. Gao X., Jayaraman S., and Gursky O. Mild oxidation promotes and advanced oxidation prevents protein dissociation and remodeling of human plasma high-density lipoprotein in vitro. J. Mol. Biol. 376 (2008) 997-1007
54. Leroy A., Toohill K.L., Fruchart J.C., and Jonas A. Structural properties of high density lipoprotein subclasses homogeneous in protein composition and size. J. Biol. Chem. 268 (1993) 4798-4805