메뉴 건너뛰기




Volumn 8, Issue 8, 2012, Pages

S Phase-Coupled E2f1 Destruction Ensures Homeostasis in Proliferating Tissues

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P35; PROTEIN RBF1; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

EID: 84866153285     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002831     Document Type: Article
Times cited : (14)

References (66)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 50149108858 scopus 로고    scopus 로고
    • Conserved functions of the pRB and E2F families
    • van den Heuvel S, Dyson NJ, (2008) Conserved functions of the pRB and E2F families. Nat Rev Mol Cell Biol 9: 713-724.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 713-724
    • van den Heuvel, S.1    Dyson, N.J.2
  • 3
    • 70349546288 scopus 로고    scopus 로고
    • Transcriptional control of the cell cycle
    • Berckmans B, De Veylder L, (2009) Transcriptional control of the cell cycle. Curr Opin Plant Biol 12: 599-605.
    • (2009) Curr Opin Plant Biol , vol.12 , pp. 599-605
    • Berckmans, B.1    de Veylder, L.2
  • 4
    • 23744484144 scopus 로고    scopus 로고
    • E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7
    • Logan N, Graham A, Zhao X, Fisher R, Maiti B, et al. (2005) E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene 24: 5000-5004.
    • (2005) Oncogene , vol.24 , pp. 5000-5004
    • Logan, N.1    Graham, A.2    Zhao, X.3    Fisher, R.4    Maiti, B.5
  • 5
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • Burkhart DL, Sage J, (2008) Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 8: 671-682.
    • (2008) Nat Rev Cancer , vol.8 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 6
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht BD, Flores O, Lees JA, Harlow E, (1994) Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev 8: 1772-1786.
    • (1994) Genes Dev , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 7
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek W, Ewen ME, Shirodkar S, Arany Z, Kaelin WG Jr, et al. (1994) Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78: 161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin Jr., W.G.5
  • 8
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek W, Xu G, Livingston DM, (1995) Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell 83: 1149-1158.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 10
    • 0033130137 scopus 로고    scopus 로고
    • Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
    • Marti A, Wirbelauer C, Scheffner M, Krek W, (1999) Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation. Nature cell biology 1: 14-19.
    • (1999) Nature Cell Biology , vol.1 , pp. 14-19
    • Marti, A.1    Wirbelauer, C.2    Scheffner, M.3    Krek, W.4
  • 11
    • 37749005850 scopus 로고    scopus 로고
    • Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development
    • Li J, Ran C, Li E, Gordon F, Comstock G, et al. (2008) Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell 14: 62-75.
    • (2008) Dev Cell , vol.14 , pp. 62-75
    • Li, J.1    Ran, C.2    Li, E.3    Gordon, F.4    Comstock, G.5
  • 12
    • 84859872654 scopus 로고    scopus 로고
    • Atypical E2F Repressors and Activators Coordinate Placental Development
    • Ouseph MM, Li J, Chen HZ, Pecot T, Wenzel P, et al. (2012) Atypical E2F Repressors and Activators Coordinate Placental Development. Dev Cell 22: 849-862.
    • (2012) Dev Cell , vol.22 , pp. 849-862
    • Ouseph, M.M.1    Li, J.2    Chen, H.Z.3    Pecot, T.4    Wenzel, P.5
  • 14
    • 0033558346 scopus 로고    scopus 로고
    • The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis
    • Du W, Dyson N, (1999) The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. The EMBO journal 18: 916-925.
    • (1999) The EMBO Journal , vol.18 , pp. 916-925
    • Du, W.1    Dyson, N.2
  • 15
    • 0029044951 scopus 로고
    • The transcription factor E2F is required for S phase during Drosophila embryogenesis
    • Duronio RJ, O'Farrell PH, Xie JE, Brook A, Dyson N, (1995) The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev 9: 1445-1455.
    • (1995) Genes Dev , vol.9 , pp. 1445-1455
    • Duronio, R.J.1    O'Farrell, P.H.2    Xie, J.E.3    Brook, A.4    Dyson, N.5
  • 16
    • 0030003157 scopus 로고    scopus 로고
    • Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells
    • Brook A, Xie JE, Du W, Dyson N, (1996) Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J 15: 3676-3683.
    • (1996) EMBO J , vol.15 , pp. 3676-3683
    • Brook, A.1    Xie, J.E.2    Du, W.3    Dyson, N.4
  • 17
    • 0032568795 scopus 로고    scopus 로고
    • Coordination of growth and cell division in the Drosophila wing
    • Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA, (1998) Coordination of growth and cell division in the Drosophila wing. Cell 93: 1183-1193.
    • (1998) Cell , vol.93 , pp. 1183-1193
    • Neufeld, T.P.1    de la Cruz, A.F.2    Johnston, L.A.3    Edgar, B.A.4
  • 20
    • 0029747143 scopus 로고    scopus 로고
    • Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs
    • Asano M, Nevins JR, Wharton RP, (1996) Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev 10: 1422-1432.
    • (1996) Genes Dev , vol.10 , pp. 1422-1432
    • Asano, M.1    Nevins, J.R.2    Wharton, R.P.3
  • 21
    • 0029954340 scopus 로고    scopus 로고
    • Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye
    • Du W, Xie JE, Dyson N, (1996) Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J 15: 3684-3692.
    • (1996) EMBO J , vol.15 , pp. 3684-3692
    • Du, W.1    Xie, J.E.2    Dyson, N.3
  • 23
    • 33749592371 scopus 로고    scopus 로고
    • A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis
    • Moon NS, Di Stefano L, Dyson N, (2006) A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis. Mol Cell Biol 26: 7601-7615.
    • (2006) Mol Cell Biol , vol.26 , pp. 7601-7615
    • Moon, N.S.1    Di Stefano, L.2    Dyson, N.3
  • 24
    • 50849132549 scopus 로고    scopus 로고
    • E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage
    • Moon NS, Di Stefano L, Morris EJ, Patel R, White K, et al. (2008) E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genet 4: e1000153 doi:10.1371/journal.pgen.1000153.
    • (2008) PLoS Genet , vol.4
    • Moon, N.S.1    Di Stefano, L.2    Morris, E.J.3    Patel, R.4    White, K.5
  • 25
    • 26444452667 scopus 로고    scopus 로고
    • Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development
    • Moon NS, Frolov MV, Kwon EJ, Di Stefano L, Dimova DK, et al. (2005) Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Dev Cell 9: 463-475.
    • (2005) Dev Cell , vol.9 , pp. 463-475
    • Moon, N.S.1    Frolov, M.V.2    Kwon, E.J.3    Di Stefano, L.4    Dimova, D.K.5
  • 26
    • 77956402972 scopus 로고    scopus 로고
    • E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila
    • Wichmann A, Uyetake L, Su TT, (2010) E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila. Dev Biol 346: 80-89.
    • (2010) Dev Biol , vol.346 , pp. 80-89
    • Wichmann, A.1    Uyetake, L.2    Su, T.T.3
  • 27
    • 0141706827 scopus 로고    scopus 로고
    • Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway
    • Dimova DK, Stevaux O, Frolov MV, Dyson NJ, (2003) Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev 17: 2308-2320.
    • (2003) Genes Dev , vol.17 , pp. 2308-2320
    • Dimova, D.K.1    Stevaux, O.2    Frolov, M.V.3    Dyson, N.J.4
  • 28
    • 80052435223 scopus 로고    scopus 로고
    • mir-11 limits the proapoptotic function of its host gene, dE2f1
    • Truscott M, Islam AB, Lopez-Bigas N, Frolov MV, (2011) mir-11 limits the proapoptotic function of its host gene, dE2f1. Genes Dev 25: 1820-1834.
    • (2011) Genes Dev , vol.25 , pp. 1820-1834
    • Truscott, M.1    Islam, A.B.2    Lopez-Bigas, N.3    Frolov, M.V.4
  • 29
    • 33847356955 scopus 로고    scopus 로고
    • Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis
    • Shibutani S, Swanhart LM, Duronio RJ, (2007) Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis. Development 134: 467-478.
    • (2007) Development , vol.134 , pp. 467-478
    • Shibutani, S.1    Swanhart, L.M.2    Duronio, R.J.3
  • 30
    • 2442677837 scopus 로고    scopus 로고
    • Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila
    • Heriche JK, Ang D, Bier E, O'Farrell PH, (2003) Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila. BMC Genet 4: 9.
    • (2003) BMC Genet , vol.4 , pp. 9
    • Heriche, J.K.1    Ang, D.2    Bier, E.3    O'Farrell, P.H.4
  • 31
    • 1942485888 scopus 로고    scopus 로고
    • Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing
    • Reis T, Edgar BA, (2004) Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing. Cell 117: 253-264.
    • (2004) Cell , vol.117 , pp. 253-264
    • Reis, T.1    Edgar, B.A.2
  • 32
    • 57049097607 scopus 로고    scopus 로고
    • Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase
    • Shibutani ST, de la Cruz AF, Tran V, Turbyfill WJ 3rd, Reis T, et al. (2008) Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase. Dev Cell 15: 890-900.
    • (2008) Dev Cell , vol.15 , pp. 890-900
    • Shibutani, S.T.1    de la Cruz, A.F.2    Tran, V.3    Turbyfill 3rd, W.J.4    Reis, T.5
  • 33
    • 79551564537 scopus 로고    scopus 로고
    • CRL4Cdt2: master coordinator of cell cycle progression and genome stability
    • Abbas T, Dutta A, (2011) CRL4Cdt2: master coordinator of cell cycle progression and genome stability. Cell cycle 10: 241-249.
    • (2011) Cell Cycle , vol.10 , pp. 241-249
    • Abbas, T.1    Dutta, A.2
  • 34
    • 80051525031 scopus 로고    scopus 로고
    • Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase
    • Havens CG, Walter JC, (2011) Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase. Genes Dev 25: 1568-1582.
    • (2011) Genes Dev , vol.25 , pp. 1568-1582
    • Havens, C.G.1    Walter, J.C.2
  • 35
    • 0014973573 scopus 로고
    • Parameters of the wing imaginal disc development of Drosophila melanogaster
    • Garcia-Bellido A, Merriam JR, (1971) Parameters of the wing imaginal disc development of Drosophila melanogaster. Dev Biol 24: 61-87.
    • (1971) Dev Biol , vol.24 , pp. 61-87
    • Garcia-Bellido, A.1    Merriam, J.R.2
  • 36
    • 69549105422 scopus 로고    scopus 로고
    • Apoptosis in Drosophila: compensatory proliferation and undead cells
    • Martin FA, Perez-Garijo A, Morata G, (2009) Apoptosis in Drosophila: compensatory proliferation and undead cells. Int J Dev Biol 53: 1341-1347.
    • (2009) Int J Dev Biol , vol.53 , pp. 1341-1347
    • Martin, F.A.1    Perez-Garijo, A.2    Morata, G.3
  • 37
    • 29144453339 scopus 로고    scopus 로고
    • Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila
    • Perez-Garijo A, Martin FA, Struhl G, Morata G, (2005) Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila. Proc Natl Acad Sci U S A 102: 17664-17669.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17664-17669
    • Perez-Garijo, A.1    Martin, F.A.2    Struhl, G.3    Morata, G.4
  • 38
    • 5044248528 scopus 로고    scopus 로고
    • Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways
    • Ryoo HD, Gorenc T, Steller H, (2004) Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev Cell 7: 491-501.
    • (2004) Dev Cell , vol.7 , pp. 491-501
    • Ryoo, H.D.1    Gorenc, T.2    Steller, H.3
  • 39
    • 3342881896 scopus 로고    scopus 로고
    • Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role
    • Huh JR, Guo M, Hay BA, (2004) Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Curr Biol 14: 1262-1266.
    • (2004) Curr Biol , vol.14 , pp. 1262-1266
    • Huh, J.R.1    Guo, M.2    Hay, B.A.3
  • 40
    • 67649641658 scopus 로고    scopus 로고
    • Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2
    • Havens CG, Walter JC, (2009) Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2. Mol Cell 35: 93-104.
    • (2009) Mol Cell , vol.35 , pp. 93-104
    • Havens, C.G.1    Walter, J.C.2
  • 41
    • 49649122013 scopus 로고    scopus 로고
    • Flow cytometric analysis of Drosophila cells
    • de la Cruz AF, Edgar BA, (2008) Flow cytometric analysis of Drosophila cells. Methods Mol Biol 420: 373-389.
    • (2008) Methods Mol Biol , vol.420 , pp. 373-389
    • de la Cruz, A.F.1    Edgar, B.A.2
  • 42
    • 0033559030 scopus 로고    scopus 로고
    • Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
    • Zheng N, Fraenkel E, Pabo CO, Pavletich NP, (1999) Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev 13: 666-674.
    • (1999) Genes Dev , vol.13 , pp. 666-674
    • Zheng, N.1    Fraenkel, E.2    Pabo, C.O.3    Pavletich, N.P.4
  • 43
    • 3142672296 scopus 로고    scopus 로고
    • E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains
    • Logan N, Delavaine L, Graham A, Reilly C, Wilson J, et al. (2004) E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains. Oncogene 23: 5138-5150.
    • (2004) Oncogene , vol.23 , pp. 5138-5150
    • Logan, N.1    Delavaine, L.2    Graham, A.3    Reilly, C.4    Wilson, J.5
  • 44
    • 0043026892 scopus 로고    scopus 로고
    • Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development
    • Weng L, Zhu C, Xu J, Du W, (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J 22: 3865-3875.
    • (2003) EMBO J , vol.22 , pp. 3865-3875
    • Weng, L.1    Zhu, C.2    Xu, J.3    Du, W.4
  • 45
    • 0033118363 scopus 로고    scopus 로고
    • ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP
    • Royzman I, Austin RJ, Bosco G, Bell SP, Orr-Weaver TL, (1999) ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes Dev 13: 827-840.
    • (1999) Genes Dev , vol.13 , pp. 827-840
    • Royzman, I.1    Austin, R.J.2    Bosco, G.3    Bell, S.P.4    Orr-Weaver, T.L.5
  • 47
    • 69449105296 scopus 로고    scopus 로고
    • Pattern formation in the Drosophila eye disc
    • Roignant JY, Treisman JE, (2009) Pattern formation in the Drosophila eye disc. Int J Dev Biol 53: 795-804.
    • (2009) Int J Dev Biol , vol.53 , pp. 795-804
    • Roignant, J.Y.1    Treisman, J.E.2
  • 48
    • 16244392774 scopus 로고    scopus 로고
    • Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye
    • Firth LC, Baker NE, (2005) Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye. Dev Cell 8: 541-551.
    • (2005) Dev Cell , vol.8 , pp. 541-551
    • Firth, L.C.1    Baker, N.E.2
  • 49
    • 0037370474 scopus 로고    scopus 로고
    • Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells
    • Cayirlioglu P, Ward WO, Silver Key SC, Duronio RJ, (2003) Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. Mol Cell Biol 23: 2123-2134.
    • (2003) Mol Cell Biol , vol.23 , pp. 2123-2134
    • Cayirlioglu, P.1    Ward, W.O.2    Silver Key, S.C.3    Duronio, R.J.4
  • 50
    • 70349298306 scopus 로고    scopus 로고
    • The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues
    • Nicholson SC, Gilbert MM, Nicolay BN, Frolov MV, Moberg KH, (2009) The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues. Curr Biol 19: 1503-1510.
    • (2009) Curr Biol , vol.19 , pp. 1503-1510
    • Nicholson, S.C.1    Gilbert, M.M.2    Nicolay, B.N.3    Frolov, M.V.4    Moberg, K.H.5
  • 51
    • 58649089776 scopus 로고    scopus 로고
    • Regulation of apoptosis of rbf mutant cells during Drosophila development
    • Tanaka-Matakatsu M, Xu J, Cheng L, Du W, (2009) Regulation of apoptosis of rbf mutant cells during Drosophila development. Dev Biol 326: 347-356.
    • (2009) Dev Biol , vol.326 , pp. 347-356
    • Tanaka-Matakatsu, M.1    Xu, J.2    Cheng, L.3    Du, W.4
  • 52
    • 68149098892 scopus 로고    scopus 로고
    • Regulation of Drosophila melanogaster pro-apoptotic gene hid
    • Bilak A, Su TT, (2009) Regulation of Drosophila melanogaster pro-apoptotic gene hid. Apoptosis 14: 943-949.
    • (2009) Apoptosis , vol.14 , pp. 943-949
    • Bilak, A.1    Su, T.T.2
  • 53
    • 0029161958 scopus 로고
    • The head involution defective gene of Drosophila melanogaster functions in programmed cell death
    • Grether ME, Abrams JM, Agapite J, White K, Steller H, (1995) The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev 9: 1694-1708.
    • (1995) Genes Dev , vol.9 , pp. 1694-1708
    • Grether, M.E.1    Abrams, J.M.2    Agapite, J.3    White, K.4    Steller, H.5
  • 54
    • 0029742260 scopus 로고    scopus 로고
    • grim, a novel cell death gene in Drosophila
    • Chen P, Nordstrom W, Gish B, Abrams JM, (1996) grim, a novel cell death gene in Drosophila. Genes Dev 10: 1773-1782.
    • (1996) Genes Dev , vol.10 , pp. 1773-1782
    • Chen, P.1    Nordstrom, W.2    Gish, B.3    Abrams, J.M.4
  • 55
    • 0030856868 scopus 로고    scopus 로고
    • Baculovirus interaction with host apoptotic pathways
    • Miller LK, (1997) Baculovirus interaction with host apoptotic pathways. Journal of cellular physiology 173: 178-182.
    • (1997) Journal of Cellular Physiology , vol.173 , pp. 178-182
    • Miller, L.K.1
  • 57
    • 82555176576 scopus 로고    scopus 로고
    • Control of Drosophila endocycles by E2F and CRL4(CDT2)
    • Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, et al. (2011) Control of Drosophila endocycles by E2F and CRL4(CDT2). Nature 480: 123-127.
    • (2011) Nature , vol.480 , pp. 123-127
    • Zielke, N.1    Kim, K.J.2    Tran, V.3    Shibutani, S.T.4    Bravo, M.J.5
  • 58
    • 0346034998 scopus 로고    scopus 로고
    • The contribution of E2F-regulated transcription to Drosophila PCNA gene function
    • Thacker SA, Bonnette PC, Duronio RJ, (2003) The contribution of E2F-regulated transcription to Drosophila PCNA gene function. Curr Biol 13: 53-58.
    • (2003) Curr Biol , vol.13 , pp. 53-58
    • Thacker, S.A.1    Bonnette, P.C.2    Duronio, R.J.3
  • 59
    • 1642540218 scopus 로고    scopus 로고
    • Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage
    • Brodsky MH, Weinert BT, Tsang G, Rong YS, McGinnis NM, et al. (2004) Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Molecular and cellular biology 24: 1219-1231.
    • (2004) Molecular and Cellular Biology , vol.24 , pp. 1219-1231
    • Brodsky, M.H.1    Weinert, B.T.2    Tsang, G.3    Rong, Y.S.4    McGinnis, N.M.5
  • 60
    • 0028980858 scopus 로고
    • Developmental control of the G1 to S transition in Drosophila: cyclin E is a limiting downstream target of E2F
    • Duronio RJ, O'Farrell PH, (1995) Developmental control of the G1 to S transition in Drosophila: cyclin E is a limiting downstream target of E2F. Genes Dev 9: 1456-1468.
    • (1995) Genes Dev , vol.9 , pp. 1456-1468
    • Duronio, R.J.1    O'Farrell, P.H.2
  • 61
    • 84863992197 scopus 로고    scopus 로고
    • A dual Role for the dREAM/MMB complex in the regulation of differentiation-specific E2F/RB target genes
    • Lee H, Ragusano L, Martinez A, Gill J, Dimova DK, (2012) A dual Role for the dREAM/MMB complex in the regulation of differentiation-specific E2F/RB target genes. Mol Cell Biol.
    • (2012) Mol Cell Biol
    • Lee, H.1    Ragusano, L.2    Martinez, A.3    Gill, J.4    Dimova, D.K.5
  • 62
    • 36248935601 scopus 로고    scopus 로고
    • Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells
    • Georlette D, Ahn S, MacAlpine DM, Cheung E, Lewis PW, et al. (2007) Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells. Genes Dev 21: 2880-2896.
    • (2007) Genes Dev , vol.21 , pp. 2880-2896
    • Georlette, D.1    Ahn, S.2    MacAlpine, D.M.3    Cheung, E.4    Lewis, P.W.5
  • 63
    • 84857167551 scopus 로고    scopus 로고
    • Pumilio facilitates miRNA regulation of the E2F3 oncogene
    • Miles WO, Tschop K, Herr A, Ji JY, Dyson NJ, (2012) Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes Dev 26: 356-368.
    • (2012) Genes Dev , vol.26 , pp. 356-368
    • Miles, W.O.1    Tschop, K.2    Herr, A.3    Ji, J.Y.4    Dyson, N.J.5
  • 64
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh JK, Fredersdorf S, Kouzarides T, Martin K, Lu X, (1997) E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes & development 11: 1840-1852.
    • (1997) Genes & Development , vol.11 , pp. 1840-1852
    • Hsieh, J.K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 65
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F-1
    • Phillips AC, Bates S, Ryan KM, Helin K, Vousden KH, (1997) Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 11: 1853-1863.
    • (1997) Genes Dev , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 66
    • 70149096483 scopus 로고    scopus 로고
    • The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback
    • Aligianni S, Lackner DH, Klier S, Rustici G, Wilhelm BT, et al. (2009) The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback. PLoS Genet 5: e1000626 doi:10.1371/journal.pgen.1000626.
    • (2009) PLoS Genet , vol.5
    • Aligianni, S.1    Lackner, D.H.2    Klier, S.3    Rustici, G.4    Wilhelm, B.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.