Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing

Cell

Volumn 117, Issue 2, 2004, Pages 253-264

  Reis, Tânia ^a,b   Edgar, Bruce A ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 25; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DE2F1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; ENZYME ACTIVITY; FEEDBACK SYSTEM; FORELIMB; HOMEOSTASIS; METAPHASE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALIA;

EID: 1942485888     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00247-8     Document Type: Article

References (65)

1. Asano M., Nevins J.R., Wharton R.P. Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev. 10:1996;1422-1432.
2. Bartkova J., Lukas J., Guldberg P., Alsner J., Kirkin A.F., Zeuthen J., Bartek J. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res. 56:1996;5475-5483.
3. Bosco G., Du W., Orr-Weaver T.L. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 3:2001;289-295.
4. Brook A., Xie J.E., Du W., Dyson N. Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J. 15:1996;3676-3683.
5. Campanero M.R., Flemington E.K. Regulation of E2F through ubiquitin-proteasome-dependent degradation. stabilization by the pRB tumor suppressor protein Proc. Natl. Acad. Sci. USA. 94:1997;2221-2226.
6. Campbell S.D., Sprenger F., Edgar B.A., O'Farrell P.H. Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. Mol. Biol. Cell. 6:1995;1333-1347.
7. de Nooij J.C., Letendre M.A., Hariharan I.K. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell. 87:1996;1237-1247.
8. DeSalle L.M., Pagano M. Regulation of the G1 to S transition by the ubiquitin pathway. FEBS Lett. 490:2001;179-189.
9. Dimova D.K., Stevaux O., Frolov M.V., Dyson N.J. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev. 17:2003;2308-2320.
10. Du W., Vidal M., Xie J.E., Dyson N. RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev. 10:1996;1206-1218.
11. Duronio R.J., O'Farrell P.H. Developmental control of the G1 to S transition in Drosophila. cyclin E is a limiting downstream target of E2F Genes Dev. 9:1995;1456-1468.
12. Duronio R.J., O'Farrell P.H., Xie J.E., Brook A., Dyson N. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 9:1995;1445-1455.
13. Duronio R.J., Brook A., Dyson N., O'Farrell P.H. E2F-induced S phase requires cyclin E. Genes Dev. 10:1996;2505-2513.
14. Duronio R.J., Bonnette P.C., O'Farrell P.H. Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition. Mol. Cell. Biol. 18:1998;141-151.
15. Dynlacht B.D., Moberg K., Lees J.A., Harlow E., Zhu L. Specific regulation of E2F family members by cyclin-dependent kinases. Mol. Cell. Biol. 17:1997;3867-3875.
16. Edgar B.A., Datar S.A. Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. Genes Dev. 10:1996;1966-1977.
17. Edgar B.A., O'Farrell P.H. Genetic control of cell division patterns in the Drosophila embryo. Cell. 57:1989;177-187.
18. Edgar B.A., O'Farrell P.H. The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell. 62:1990;469-480.
19. Edgar B.A., Sprenger F., Duronio R.J., Leopold P., O'Farrell P.H. Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev. 8:1994;440-452.
20. Frolov M.V., Huen D.S., Stevaux O., Dimova D., Balczarek-Strang K., Elsdon M., Dyson N.J. Functional antagonism between E2F family members. Genes Dev. 15:2001;2146-2160.
21. Garcia-Bellido A., Merriam J.R. Parameters of the wing imaginal disc development of Drosophila melanogaster. Dev. Biol. 24:1971;61-87.
22. Gautier J., Matsukawa T., Nurse P., Maller J. Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature. 339:1989;626-629.
23. Grosshans J., Wieschaus E. A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell. 101:2000;523-531.
24. Hateboer G., Kerkhoven R.M., Shvarts A., Bernards R., Beijersbergen R.L. Degradation of E2F by the ubiquitin-proteasome pathway. regulation by retinoblastoma family proteins and adenovirus transforming proteins Genes Dev. 10:1996;2960-2970.
25. Heriche J.K., Ang D., Bier E., O'Farrell P.H. Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila. BMC Genet. 4:2003;9.
26. Hofmann F., Martelli F., Livingston D.M., Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10:1996;2949-2959.
27. Ishida S., Huang E., Zuzan H., Spang R., Leone G., West M., Nevins J.R. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol. Cell. Biol. 21:2001;4684-4699.
28. Johnson D.G., Ohtani K., Nevins J.R. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev. 8:1994;1514-1525.
29. Johnston L.A., Schubiger G. Ectopic expression of wingless in imaginal discs interferes with decapentaplegic expression and alters cell determination. Development. 122:1996;3519-3529.
30. Johnston L.A., Prober D.A., Edgar B.A., Eisenman R.N., Gallant P. Drosophila myc regulates cellular growth during development. Cell. 98:1999;779-790.
31. Knoblich J.A., Sauer K., Jones L., Richardson H., Saint R., Lehner C.F. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77:1994;107-120.
32. Krek W. Proteolysis and the G1-S transition. the SCF connection Curr. Opin. Genet. Dev. 8:1998;36-42.
33. Krek W., Ewen M.E., Shirodkar S., Arany Z., Kaelin W.G. Jr., Livingston D.M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell. 78:1994;161-172.
34. Kylsten P., Saint R. Imaginal tissues of Drosophila melanogaster exhibit different modes of cell proliferation control. Dev. Biol. 192:1997;509-522.
35. Lane M.E., Sauer K., Wallace K., Jan Y.N., Lehner C.F., Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 87:1996;1225-1235.
36. Lehner C.F., O'Farrell P.H. Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell. 56:1989;957-968.
37. Madhavan M., Schneiderman H.A. Histological analysis of the dynamics of growth of imaginal discs and histoblast nests during the larval development of Drosophila melonogaster. Rouxs Arch. Dev. Biol. 183:1977;269-305.
38. Martelli F., Livingston D.M. Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. Proc. Natl. Acad. Sci. USA. 96:1999;2858-2863.
39. Marti A., Wirbelauer C., Scheffner M., Krek W. Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation. Nat. Cell Biol. 1:1999;14-19.
40. Mata J., Curado S., Ephrussi A., Rorth P. Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis. Cell. 101:2000;511-522.
41. Milan M., Campuzano S., Garcia-Bellido A. Cell cycling and patterned cell proliferation in the Drosophila wing during metamorphosis. Proc. Natl. Acad. Sci. USA. 93:1996;11687-11692. a.
42. Milan M., Campuzano S., Garcia-Bellido A. Cell cycling and patterned cell proliferation in the wing primordium of Drosophila. Proc. Natl. Acad. Sci. USA. 93:1996;640-645. b.
43. Murray A.W., Kirschner M.W. Cyclin synthesis drives the early embryonic cell cycle. Nature. 339:1989;275-280.
44. Murray A.W., Solomon M.J., Kirschner M.W. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature. 339:1989;280-286.
45. Nash R., Tokiwa G., Anand S., Erickson K., Futcher A.B. The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J. 7:1988;4335-4346.
46. Neufeld T.P., de la Cruz A.F., Johnston L.A., Edgar B.A. Coordination of growth and cell division in the Drosophila wing. Cell. 93:1998;1183-1193.
47. Nurse P., Thuriaux P. Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. Genetics. 96:1980;627-637.
48. O'Neill J.W., Bier E. Double-label in situ hybridization using biotin and digoxigenin-tagged RNA probes. Biotechniques. 17:1994;870-874., 875.
49. Ohtsubo M., Roberts J.M. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science. 259:1993;1908-1912.
50. Ohtsubo M., Theodoras A.M., Schumacher J., Roberts J.M., Pagano M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol. Cell. Biol. 15:1995;2612-2624.
51. Pignoni F., Zipursky S.L. Induction of Drosophila eye development by decapentaplegic. Development. 124:1997;271-278.
52. Price D., Rabinovitch S., O'Farrell P.H., Campbell S.D. Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. Genetics. 155:2000;159-166.
53. Prober D.A., Edgar B.A. Ras1 promotes cellular growth in the Drosophila wing. Cell. 100:2000;435-446.
54. Resnitzky D., Gossen M., Bujard H., Reed S.I. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol. 14:1994;1669-1679.
55. Royzman I., Whittaker A.J., Orr-Weaver T.L. Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev. 11:1997;1999-2011.
56. Russell P., Nurse P. cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell. 45:1986;145-153.
57. Saucedo L.J., Gao X., Chiarelli D.A., Li L., Pan D., Edgar B.A. Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat. Cell Biol. 5:2003;566-571.
58. Stocker H., Radimerski T., Schindelholz B., Wittwer F., Belawat P., Daram P., Breuer S., Thomas G., Hafen E. Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat. Cell Biol. 5:2003;559-566.
59. Su T.T., Sprenger F., DiGregorio P.J., Campbell S.D., O'Farrell P.H. Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev. 12:1998;1495-1503.
60. Thacker S.A., Bonnette P.C., Duronio R.J. The contribution of E2F-regulated transcription to Drosophila PCNA gene function. Curr. Biol. 13:2003;53-58.
61. Verdu J., Buratovich M.A., Wilder E.L., Birnbaum M.J. Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. Nat. Cell Biol. 1:1999;500-506.
62. Weigmann K., Cohen S.M., Lehner C.F. Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. Development. 124:1997;3555-3563.
63. Weinkove D., Neufeld T.P., Twardzik T., Waterfield M.D., Leevers S.J. Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr. Biol. 9:1999;1019-1029.
64. Weng L., Zhu C., Xu J., Du W. Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J. 22:2003;3865-3875.
65. Yamasaki L., Jacks T., Bronson R., Goillot E., Harlow E., Dyson N.J. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell. 85:1996;537-548.