Mitochondrial glutaminase release contributes to glutamate-mediated neurotoxicity during human immunodeficiency virus-1 infection

Journal of Neuroimmune Pharmacology

Volumn 7, Issue 3, 2012, Pages 619-628

  Tian, Changhai ^a   Sun, Lijun ^a   Jia, Beibei ^a   Ma, Kangmu ^a   Curthoys, Norman ^b   Ding, Jianqing ^c   Zheng, Jialin ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Veterinary Dentistry and Oral Surgery   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Glutamate and neurotoxicity; HIV 1 infection; Mitochondrial glutaminase; Oxidative stress

Indexed keywords

CYCLOSPORIN A; GLUTAMIC ACID; GLUTAMINASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME REGULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; MACROPHAGE; MITOCHONDRION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; FETUS; GLUTAMIC ACID; GLUTAMINASE; HIV INFECTIONS; HIV-1; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84866141013     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9364-1     Document Type: Article

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