Lycium barbarum polysaccharide stimulates proliferation of MCF-7 cells by the ERK pathway

Life Sciences

Volumn 91, Issue 9-10, 2012, Pages 353-357

  Shen, Lingling ^a   Du, Guang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Breast cancer; Cell cycle; ERK pathway; Lycium barbarum polysaccharide

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE; POLYSACCHARIDE; PROTEIN P21; PROTEIN P53;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; LYCIUM; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; S PHASE CELL CYCLE CHECKPOINTS; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

LYCIUM BARBARUM;

EID: 84866085174     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.08.012     Document Type: Article

References (36)

1. H. Amagase, and D.M. Nance A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (Goji) juice, GoChi J Altern Complement Med 14 2008 403 412
2. H. Amagase, B. Sun, and C. Borek Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults Nutr Res 29 2009 19 25
3. B. Bose, L. Motiwale, and K.V. Rao DNA damage and G2/M arrest in Syrian hamster embryo cells during Malachite green exposure are associated with elevated phosphorylation of ERK1 and JNK1 Cancer Lett 230 2005 260 270
4. M.S. Butler Natural products to drugs: natural product-derived compounds in clinical trials Nat Prod Rep 25 2008 475 516
5. G.W. Cao, W.G. Yang, and P. Du Observation of the effects of LAK/IL-2 therapy combining with Lycium barbarum polysaccharides in the treatment of 75 cancer patients Zhonghua Zhong Liu Za Zhi 16 1994 428 431
6. J.C. Chambard, R. Lefloch, J. Pouyssegur, and P. Lenormand ERK implication in cell cycle regulation Biochim Biophys Acta 1773 2007 1299 1310
7. R.C. Chang, and K.F. So Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? Cell Mol Neurobiol 28 2008 643 652
8. D. Das, G. Pintucci, and A. Stern MAPK-dependent expression of p21 (WAF) and p27 (kip1) in PMA-induced differentiation of HL60 cells FEBS Lett 472 2000 50 52
9. G. Du, L. Liu, and J. Fang Experimental study on the enhancement of murine splenic lymphocyte proliferation by Lycium barbarum glycopeptide J Huazhong Univ Sci Technolog Med Sci 24 518-520 2004 527
10. L. Gan, J. Wang, and S. Zhang Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide Wei Sheng Yan Jiu 30 2001 333 335
11. L. Gan, S.H. Zhang, Q. Liu, and H.B. Xu A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells Eur J Pharmacol 471 2003 217 222
12. J. Guo, B. Xiao, Q. Liu, Z. Gong, and Y. Le Suppression of C-myc expression associates with anti-proliferation of aloe-emodin on gastric cancer cells Cancer Invest 26 2008 369 374
13. S.I. Helle The insulin-like growth factor system in advanced breast cancer Best Pract Res Clin Endocrinol Metab 18 2004 67 79
14. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
15. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, and T. Murray Cancer statistics, 2008 CA Cancer J Clin 58 2008 71 96
16. R. Koivusalo, E. Krausz, P. Ruotsalainen, H. Helenius, and S. Hietanen Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand Cancer Res 62 2002 7364 7371
17. E.J. Lee, G.S. Moon, W.S. Choi, W.J. Kim, and S.K. Moon Naringin-induced p21WAF1-mediated G(1)-phase cell cycle arrest via activation of the Ras/Raf/ERK signaling pathway in vascular smooth muscle cells Food Chem Toxicol 46 2008 3800 3807
18. X.M. Li Protective effect of Lycium barbarum polysaccharides on streptozotocin-induced oxidative stress in rats Int J Biol Macromol 40 2007 461 465
19. Q. Luo, Z. Li, J. Yan, F. Zhu, R.J. Xu, and Y.Z. Cai Lycium barbarum polysaccharides induce apoptosis in human prostate cancer cells and inhibits prostate cancer growth in a xenograft mouse model of human prostate cancer J Med Food 12 2009 695 703
20. F. Mao, B. Xiao, Z. Jiang, J. Zhao, X. Huang, and J. Guo Anticancer effect of Lycium barbarum polysaccharides on colon cancer cells involves G0/G1 phase arrest Med Oncol 28 2011 121 126
21. P. May, and E. May Twenty years of p53 research: structural and functional aspects of the p53 protein Oncogene 18 1999 7621 7636
22. J.A. McCubrey, L.S. Steelman, W.H. Chappell, S.L. Abrams, E.W. Wong, and F. Chang Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance Biochim Biophys Acta 1773 2007 1263 1284
23. S. Meloche, and J. Pouyssegur The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition Oncogene 26 2007 3227 3239
24. Y. Miao, B. Xiao, Z. Jiang, Y. Guo, F. Mao, and J. Zhao Growth inhibition and cell-cycle arrest of human gastric cancer cells by Lycium barbarum polysaccharide Med Oncol 27 2010 785 790
25. O. Potterat Goji (Lycium barbarum and L. chinense): phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity Planta Med 76 2010 7 19
26. P.P. Roux, and J. Blenis ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions Microbiol Mol Biol Rev 68 2004 320 344
27. I. Sanchez, and B.D. Dynlacht New insights into cyclins, CDKs, and cell cycle control Semin Cell Dev Biol 16 2005 311 321
28. F.A. Scholl, P.A. Dumesic, and P.A. Khavari Effects of active MEK1 expression in vivo Cancer Lett 230 2005 1 5
29. M.A. Shah, and G.K. Schwartz Cyclin-dependent kinases as targets for cancer therapy Cancer Chemother Biol Response Modif 22 2005 135 162
30. S. Singh, A.K. Upadhyay, A.K. Ajay, and M.K. Bhat p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis FEBS Lett 581 2007 289 295
31. C. Swanton Cell-cycle targeted therapies Lancet Oncol 5 2004 27 36
32. D. Tang, D. Wu, A. Hirao, J.M. Lahti, L. Liu, and B. Mazza ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53 J Biol Chem 277 2002 12710 12717
33. M. Tsujita, W.L. Batista, F.T. Ogata, A. Stern, H.P. Monteiro, and R.J. Arai The nitric oxide-sensitive p21Ras-ERK pathway mediates S- nitrosoglutathione-induced apoptosis Biochem Biophys Res Commun 369 2008 1001 1006
34. W. Zhang, and H.T. Liu MAPK signal pathways in the regulation of cell proliferation in mammalian cells Cell Res 12 2002 9 18
35. M. Zhang, H. Chen, J. Huang, Z. Li, C. Zhu, and S. Zhang Effect of Lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis Life Sci 76 2005 2115 2124
36. Qing-Yuan Zhang, Qiu-Ying Jiang, and Xu Huang Polysaccharides derived from Lycium barbarum suppress IGF-1-induced angiogenesis via PI3K/HIF-1α/VEGF signalling pathways in MCF-7 cells Food Chem 131 2012 1479 1484