Naringin-induced p21WAF1-mediated G1-phase cell cycle arrest via activation of the Ras/Raf/ERK signaling pathway in vascular smooth muscle cells

Food and Chemical Toxicology

Volumn 46, Issue 12, 2008, Pages 3800-3807

  Lee, Eo Jin ^a   Moon, Gi Seong ^a   Choi, Won Seok ^a   Kim, Wun Jae ^b   Moon, Sung Kwon ^a,b  

^a Chungju National University   (South Korea)

^b Chungbuk National University College of Medicine   (South Korea)

Author keywords

ERK Ras Raf; G1 cell cycle arrest; Naringin; p21WAF1; Vascular smooth muscle cell

Indexed keywords

AURANTIIN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; RAF PROTEIN; RAS PROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; GROWTH INHIBITION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVANONES; FLAVONOIDS; G1 PHASE; GENES, RAS; IMMUNOPRECIPITATION; MUTATION; MYOCYTES, SMOOTH MUSCLE; RAF KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; THYMIDINE; TRANSFECTION;

EID: 56149084682     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.10.002     Document Type: Article

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