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Volumn 7, Issue 3, 2012, Pages 544-556

Testing NF-kB-based therapy in hemiparkinsonian monkeys

Author keywords

Dopamine; Dopaminergic neurons; Monkey; Motor function; NF kB; Parkinson's disease

Indexed keywords

I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NEUROPROTECTIVE AGENT; NEUROTRANSMITTER; NUCLEAR FACTOR KAPPA B ESSENTIAL MODIFIER BINDING DOMAIN; UNCLASSIFIED DRUG; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; NBD PEPTIDE, MOUSE; PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84866080814     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9377-9     Document Type: Article
Times cited : (32)

References (27)
  • 1
    • 79957467314 scopus 로고    scopus 로고
    • Ageing as a primary risk factor for parkinson's disease: Evidence from studies of nonhuman primates
    • Collier TJ, Kanaan NM, Kordower JH (2011) Ageing as a primary risk factor for Parkinson's disease: evidence from studies of nonhuman primates. Nat Rev Neurosci 12:359-366
    • (2011) Nat Rev Neurosci , vol.12 , pp. 359-366
    • Collier, T.J.1    Kanaan, N.M.2    Kordower, J.H.3
  • 3
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • DOI 10.1016/S0896-6273(03)00568-3
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39:889-909 (Pubitemid 37130207)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 4
    • 0034006478 scopus 로고    scopus 로고
    • Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo
    • Dehmer T, Lindenau J, Haid S, Dichgans J, Schulz JB (2000) Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo. J Neurochem 74:2213-2216 (Pubitemid 30217680)
    • (2000) Journal of Neurochemistry , vol.74 , Issue.5 , pp. 2213-2216
    • Dehmer, T.1    Lindenau, J.2    Haid, S.3    Dichgans, J.4    Schulz, J.B.5
  • 6
    • 0043162103 scopus 로고    scopus 로고
    • Novel anti-inflammatory therapy for Parkinson's disease
    • DOI 10.1016/S0165-6147(03)00176-7
    • Gao HM, Liu B, Zhang W, Hong JS (2003) Novel anti-inflammatory therapy for Parkinson's disease. Trends Pharmacol Sci 24:395-401 (Pubitemid 36952555)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.8 , pp. 395-401
    • Gao, H.-M.1    Liu, B.2    Zhang, W.3    Hong, J.-S.4
  • 7
    • 54949147176 scopus 로고    scopus 로고
    • New regulators of nf-kappab in inflammation
    • Ghosh S, Hayden MS (2008) New regulators of NF-kappaB in inflammation. Nat Rev Immunol 8:837-848
    • (2008) Nat Rev Immunol , vol.8 , pp. 837-848
    • Ghosh, S.1    Hayden, M.S.2
  • 8
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the nf-kappab puzzle
    • Ghosh S, Karin M (2002) Missing pieces in the NF-kappaB puzzle. Cell 109(Suppl):S81-96
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 10
    • 70350555275 scopus 로고    scopus 로고
    • Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of parkinson's disease
    • Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan K (2009) Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci 29:13543-13556
    • (2009) J Neurosci , vol.29 , pp. 13543-13556
    • Ghosh, A.1    Roy, A.2    Matras, J.3    Brahmachari, S.4    Gendelman, H.E.5    Pahan, K.6
  • 13
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in nf-kappab signaling
    • Hayden MS, Ghosh S (2008) Shared principles in NF-kappaB signaling. Cell 132:344-362
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 15
    • 77957191723 scopus 로고    scopus 로고
    • Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: Implications for alzheimer's disease
    • Jana A, Pahan K (2010) Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. J Neurosci 30:12676-12689
    • (2010) J Neurosci , vol.30 , pp. 12676-12689
    • Jana, A.1    Pahan, K.2
  • 16
    • 84862486817 scopus 로고    scopus 로고
    • Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective parkinson disease protein dj-1 in astrocytes and neurons
    • Khasnavis S, Pahan K (2012) Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective parkinson disease protein DJ-1 in astrocytes and neurons. J Neuroimmune Pharmacol 7:424-435
    • (2012) J Neuroimmune Pharmacol , vol.7 , pp. 424-435
    • Khasnavis, S.1    Pahan, K.2
  • 18
    • 33845993229 scopus 로고    scopus 로고
    • Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
    • DOI 10.1002/ana.21032
    • Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J 3rd, Gasmi M, Bartus RT (2006) Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60:706-715 (Pubitemid 46048488)
    • (2006) Annals of Neurology , vol.60 , Issue.6 , pp. 706-715
    • Kordower, J.H.1    Herzog, C.D.2    Dass, B.3    Bakay, R.A.E.4    Stansell III, J.5    Gasmi, M.6    Bartus, R.T.7
  • 19
    • 0034284715 scopus 로고    scopus 로고
    • Selective inhibition of nf-kappab activation by a peptide that blocks the interaction of nemo with the ikappab kinase complex
    • May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S (2000) Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 289:1550-1554
    • (2000) Science , vol.289 , pp. 1550-1554
    • May, M.J.1    D'Acquisto, F.2    Madge, L.A.3    Glockner, J.4    Pober, J.S.5    Ghosh, S.6
  • 20
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)-1β, IL-2, IL-4, IL-6 and transforming growth factor-α levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease
    • DOI 10.1016/0304-3940(96)12706-3
    • Mogi M, Harada M, Narabayashi H, Inagaki H, Minami M, Nagatsu T (1996) Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. Neurosci Lett 211:13-16 (Pubitemid 26228016)
    • (1996) Neuroscience Letters , vol.211 , Issue.1 , pp. 13-16
    • Mogi, M.1    Harada, M.2    Narabayashi, H.3    Inagaki, H.4    Minami, M.5    Nagatsu, T.6
  • 22
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • DOI 10.1146/annurev.neuro.22.1.123
    • Olanow CW, Tatton WG (1999) Etiology and pathogenesis of Parkinson's disease. Annu Rev Neurosci 22:123-144 (Pubitemid 29144883)
    • (1999) Annual Review of Neuroscience , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 24
    • 79956070020 scopus 로고    scopus 로고
    • Prospects of statins in parkinson disease
    • Roy A, Pahan K (2011) Prospects of statins in Parkinson disease. Neuroscientist 17:244-255
    • (2011) Neuroscientist , vol.17 , pp. 244-255
    • Roy, A.1    Pahan, K.2
  • 25
    • 33745807628 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase gene in glial cells
    • DOI 10.1089/ars.2006.8.929
    • Saha RN, Pahan K (2006) Regulation of inducible nitric oxide synthase gene in glial cells. Antioxid Redox Signal 8:929-947 (Pubitemid 44036510)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.5-6 , pp. 929-947
    • Saha, R.N.1    Pahan, K.2
  • 26
    • 33747379123 scopus 로고    scopus 로고
    • Up-regulation of BDNF in astrocytes by TNF-α: A case for the neuroprotective role of cytokine
    • DOI 10.1007/s11481-006-9020-8
    • Saha RN, Liu X, Pahan K (2006) Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol 1:212-222 (Pubitemid 44244127)
    • (2006) Journal of Neuroimmune Pharmacology , vol.1 , Issue.3 , pp. 212-222
    • Saha, R.N.1    Liu, X.2    Pahan, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.