-
1
-
-
0032925674
-
Combination of hypoxia/aglycemia compromises in vitro BBB integrity
-
Abbruscato TJ, Davis TP. 1999. Combination of hypoxia/aglycemia compromises in vitro BBB integrity. J Pharmacol Exp Ther 289:668-675.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 668-675
-
-
Abbruscato, T.J.1
Davis, T.P.2
-
2
-
-
0025102678
-
The use of cultured epithelial and endothelial cells for drug transport and metabolism studies
-
Audus KL, Bartel RL, Hidalgo IJ, Borchardt RT. 1990. The use of cultured epithelial and endothelial cells for drug transport and metabolism studies. Pharm Res 7:435-451.
-
(1990)
Pharm Res
, vol.7
, pp. 435-451
-
-
Audus, K.L.1
Bartel, R.L.2
Hidalgo, I.J.3
Borchardt, R.T.4
-
3
-
-
0023633555
-
Bovine brain microvessel endothelial cell monolayers as a model system for the blood-brain barrier
-
Audus KL, Borchardt RT. 1987. Bovine brain microvessel endothelial cell monolayers as a model system for the blood-brain barrier. Ann NY Acad Sci 507:9-18.
-
(1987)
Ann NY Acad Sci
, vol.507
, pp. 9-18
-
-
Audus, K.L.1
Borchardt, R.T.2
-
4
-
-
0032851468
-
Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: Influence of astrocyte contact
-
Abbruscato TJ, Davis TP. 1999. Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: Influence of astrocyte contact. Brain Res 842:277-286.
-
(1999)
Brain Res
, vol.842
, pp. 277-286
-
-
Abbruscato, T.J.1
Davis, T.P.2
-
5
-
-
0036891988
-
Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells
-
Abbruscato TJ, Lopez SP, Mark KS, Hawkins BT, Davis TP. 2002. Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. J Pharm Sci 91:2525-2538.
-
(2002)
J Pharm Sci
, vol.91
, pp. 2525-2538
-
-
Abbruscato, T.J.1
Lopez, S.P.2
Mark, K.S.3
Hawkins, B.T.4
Davis, T.P.5
-
6
-
-
0027931494
-
Effect of peptidases at the blood-brain barrier on the permeability of enkephalin
-
Brownson EA, Abbruscato TJ, Gillespie TJ, Hruby VJ, Davis TP. 1994. Effect of peptidases at the blood-brain barrier on the permeability of enkephalin. J Pharmacol Exp Ther 270:675-680.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 675-680
-
-
Brownson, E.A.1
Abbruscato, T.J.2
Gillespie, T.J.3
Hruby, V.J.4
Davis, T.P.5
-
7
-
-
3343007152
-
Regulation of blood-brain barrier Na,K,2Cl-cotransporter through phosphorylation during in vitro stroke conditions and nicotine exposure
-
Abbruscato TJ, Lopez SP, Roder K, Paulson JR. 2004. Regulation of blood-brain barrier Na,K,2Cl-cotransporter through phosphorylation during in vitro stroke conditions and nicotine exposure. J Pharmacol Exp Ther 310:459-468.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 459-468
-
-
Abbruscato, T.J.1
Lopez, S.P.2
Roder, K.3
Paulson, J.R.4
-
8
-
-
32544433631
-
Protein kinase C family members as a target for regulation of blood-brain barrier Na,K,2Cl-cotransporter during in vitro stroke conditions and nicotine exposure
-
Yang T, Roder KE, Bhat GJ, Thekkumkara TJ, Abbruscato TJ. 2006. Protein kinase C family members as a target for regulation of blood-brain barrier Na,K,2Cl-cotransporter during in vitro stroke conditions and nicotine exposure. Pharm Res 23:291-302.
-
(2006)
Pharm Res
, vol.23
, pp. 291-302
-
-
Yang, T.1
Roder, K.E.2
Bhat, G.J.3
Thekkumkara, T.J.4
Abbruscato, T.J.5
-
9
-
-
0035156232
-
Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier
-
Gumbleton M, Audus KL. 2001. Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. J Pharm Sci 90:1681-1698.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1681-1698
-
-
Gumbleton, M.1
Audus, K.L.2
-
10
-
-
0034896546
-
Evaluation of the BBMEC model for screening the CNS permeability of drugs
-
Otis KW, Avery ML, Broward-Partin SM, Hansen DK, Behlow HW Jr, Scott DO, Thompson TN. 2001. Evaluation of the BBMEC model for screening the CNS permeability of drugs. J Pharmacol Toxicol Methods 45:71-77.
-
(2001)
J Pharmacol Toxicol Methods
, vol.45
, pp. 71-77
-
-
Otis, K.W.1
Avery, M.L.2
Broward-Partin, S.M.3
Hansen, D.K.4
Behlow Jr, H.W.5
Scott, D.O.6
Thompson, T.N.7
-
11
-
-
0041736008
-
Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitro model for studies on chlorpyrifos transport
-
Yang J, Aschner M. 2003. Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitro model for studies on chlorpyrifos transport. Neurotoxicology 24:741-774.
-
(2003)
Neurotoxicology
, vol.24
, pp. 741-774
-
-
Yang, J.1
Aschner, M.2
-
12
-
-
0033949264
-
Primary cultures of brain microvessel endothelial cells: A valid and flexible model to study drug transport through the blood-brain barrier in vitro
-
Franke H, Galla H, Beuckmann CT. 2000. Primary cultures of brain microvessel endothelial cells: A valid and flexible model to study drug transport through the blood-brain barrier in vitro. Brain Res Protoc 5:248-256.
-
(2000)
Brain Res Protoc
, vol.5
, pp. 248-256
-
-
Franke, H.1
Galla, H.2
Beuckmann, C.T.3
-
13
-
-
11144249849
-
Evaluation of the MDR-MDCK cell line as permeability careen for the blood-brain barrier
-
Wang Q, Rager JD, Weinstein K, Kardos PS, Dobson GL, Li J, Hidalgo IJ. 2005. Evaluation of the MDR-MDCK cell line as permeability careen for the blood-brain barrier. Int J Pharm 288:349-359.
-
(2005)
Int J Pharm
, vol.288
, pp. 349-359
-
-
Wang, Q.1
Rager, J.D.2
Weinstein, K.3
Kardos, P.S.4
Dobson, G.L.5
Li, J.6
Hidalgo, I.J.7
-
14
-
-
28844437347
-
Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier
-
Kusch-Poddar M, Drewe J, Fux I, Gutmann H. 2005. Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier. Brain Res 1064:21-31.
-
(2005)
Brain Res
, vol.1064
, pp. 21-31
-
-
Kusch-Poddar, M.1
Drewe, J.2
Fux, I.3
Gutmann, H.4
-
15
-
-
0141894132
-
Evaluation of the immortalized mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies
-
Omidi Y, Campbell L, Barar J, Connell D, Akhtar S, Gumbleton M. 2003. Evaluation of the immortalized mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies. Brain Res 990:95-112.
-
(2003)
Brain Res
, vol.990
, pp. 95-112
-
-
Omidi, Y.1
Campbell, L.2
Barar, J.3
Connell, D.4
Akhtar, S.5
Gumbleton, M.6
-
16
-
-
33845966079
-
Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells
-
Brown RC, Morris AP, O'neil RG. 2007. Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells. Brain Res 1130:17-30.
-
(2007)
Brain Res
, vol.1130
, pp. 17-30
-
-
Brown, R.C.1
Morris, A.P.2
O'neil, R.G.3
-
17
-
-
0024405955
-
Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment
-
Williams RL, Risau W, Zerwes HG, Drexler H, Aguzzi A, Wagner EF. 1989. Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment. Cell 57:1053-1063.
-
(1989)
Cell
, vol.57
, pp. 1053-1063
-
-
Williams, R.L.1
Risau, W.2
Zerwes, H.G.3
Drexler, H.4
Aguzzi, A.5
Wagner, E.F.6
-
18
-
-
0028414915
-
Oncogenes in the study of endothelial cell growth and differentiation
-
Wagner EF, Risau W. 1994. Oncogenes in the study of endothelial cell growth and differentiation. Semin Cancer Biol 5:137-145.
-
(1994)
Semin Cancer Biol
, vol.5
, pp. 137-145
-
-
Wagner, E.F.1
Risau, W.2
-
19
-
-
0031041789
-
Immunosurveillance modeled in vitro: Naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium
-
Rohnelt RK, Hoch G, Reiss Y, Engelhardt B. 1997. Immunosurveillance modeled in vitro: Naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium. Int Immunol 9:435-150.
-
(1997)
Int Immunol
, vol.9
, pp. 435-150
-
-
Rohnelt, R.K.1
Hoch, G.2
Reiss, Y.3
Engelhardt, B.4
-
20
-
-
0024440722
-
Involvement relative importance of at least two distinct mechanisms in the effects of 2-mercaptoethanol on murine lymphocytes in culture
-
Pruett SB, Obiri N, Kiel JL. 1989. Involvement relative importance of at least two distinct mechanisms in the effects of 2-mercaptoethanol on murine lymphocytes in culture. J Cell Physiol 141:40-45.
-
(1989)
J Cell Physiol
, vol.141
, pp. 40-45
-
-
Pruett, S.B.1
Obiri, N.2
Kiel, J.L.3
-
21
-
-
0026638367
-
Permeability of bovine brain microvessel endothelial cells in vitro: Barrier tightening by a factor released from astroglioma cell
-
Raub TJ, Kuentzel SL, Sawada GA. 1992. Permeability of bovine brain microvessel endothelial cells in vitro: Barrier tightening by a factor released from astroglioma cell. Exp Cell Res 199:330-340.
-
(1992)
Exp Cell Res
, vol.199
, pp. 330-340
-
-
Raub, T.J.1
Kuentzel, S.L.2
Sawada, G.A.3
-
22
-
-
0036084919
-
Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation
-
Mark KS, Davis TP. 2002. Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation. Am J Physiol 282:H1485-H1494.
-
(2002)
Am J Physiol
, vol.282
-
-
Mark, K.S.1
Davis, T.P.2
-
23
-
-
0027853643
-
Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs
-
Weber SJ, Abbruscato TJ, Brownson EA, Lipkowski AW, Plot R, Misicka A, Haaseth RC, Bartosz H, Hruby VJ, Davis TP. 1993. Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs. J Pharmacol Exp Ther 266:1649-1655.
-
(1993)
J Pharmacol Exp Ther
, vol.266
, pp. 1649-1655
-
-
Weber, S.J.1
Abbruscato, T.J.2
Brownson, E.A.3
Lipkowski, A.W.4
Plot, R.5
Misicka, A.6
Haaseth, R.C.7
Bartosz, H.8
Hruby, V.J.9
Davis, T.P.10
-
25
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CA, Vandeemter L. 1996. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 97:2517-2524.
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Vandeemter, L.4
-
26
-
-
0037384485
-
Cation-chloride co-transporters in neuronal communication, development and trauma
-
Payne JA, Rivera C, Viopio J, Kaila K. 2003. Cation-chloride co-transporters in neuronal communication, development and trauma. Trends Neurosci 26:199-206.
-
(2003)
Trends Neurosci
, vol.26
, pp. 199-206
-
-
Payne, J.A.1
Rivera, C.2
Viopio, J.3
Kaila, K.4
-
28
-
-
1842734654
-
Glucose tranporter expression in the central nervous system: Relationship to synaptic function
-
McEwen BS, Reagan LP. 2004. Glucose tranporter expression in the central nervous system: Relationship to synaptic function. Eur J Pharmacol 490:13-24.
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 13-24
-
-
McEwen, B.S.1
Reagan, L.P.2
-
29
-
-
0031239423
-
Metabolic trafficking through astrocytic gap junctions
-
Giaume C, Tabernero A, Medina JM. 1997. Metabolic trafficking through astrocytic gap junctions. Glia 21:114-123.
-
(1997)
Glia
, vol.21
, pp. 114-123
-
-
Giaume, C.1
Tabernero, A.2
Medina, J.M.3
-
30
-
-
0031896525
-
Low glucose enhances Na+/glucose transport in bovine brain artery endothelial cells
-
Nishizaki T, Matsuoka T. 1998. Low glucose enhances Na+/glucose transport in bovine brain artery endothelial cells. Stroke 29:844-849.
-
(1998)
Stroke
, vol.29
, pp. 844-849
-
-
Nishizaki, T.1
Matsuoka, T.2
-
31
-
-
1842737553
-
Localization of the Na+-D-glucose cotransporter SGLT1 in the blood-brain barrier
-
Elfeber K, Kohler A, Lutzenburg M, Osswald C, Galla HJ, Witte OW, Koepsell H. 2004. Localization of the Na+-D-glucose cotransporter SGLT1 in the blood-brain barrier. Histochem Cell Biol 121:201-207.
-
(2004)
Histochem Cell Biol
, vol.121
, pp. 201-207
-
-
Elfeber, K.1
Kohler, A.2
Lutzenburg, M.3
Osswald, C.4
Galla, H.J.5
Witte, O.W.6
Koepsell, H.7
-
32
-
-
0026073294
-
Changes in the activity of protein kinase C and the differential subcellular redistribution of its isozymes in the rat striatum during and following transient forebrain ischemia
-
Wieloch T, Cardell M, Bingren H, Zivin J, Saitoh T. 1991. Changes in the activity of protein kinase C and the differential subcellular redistribution of its isozymes in the rat striatum during and following transient forebrain ischemia. J Neurochem 56:1227-1235.
-
(1991)
J Neurochem
, vol.56
, pp. 1227-1235
-
-
Wieloch, T.1
Cardell, M.2
Bingren, H.3
Zivin, J.4
Saitoh, T.5
-
33
-
-
24144474000
-
Induction of blood-brain barrier properties in cultured brain capillary endothelial cells: Comparison between primary glial cells and C6 cell line
-
Boveri M, Berezowski V, Price A, Slupek S, Lenfant A, Benaud C, Hartung T, Cecchelli R, Prieto P, Dehouck M. 2005. Induction of blood-brain barrier properties in cultured brain capillary endothelial cells: comparison between primary glial cells and C6 cell line. Glia 51:187-198.
-
(2005)
Glia
, vol.51
, pp. 187-198
-
-
Boveri, M.1
Berezowski, V.2
Price, A.3
Slupek, S.4
Lenfant, A.5
Benaud, C.6
Hartung, T.7
Cecchelli, R.8
Prieto, P.9
Dehouck, M.10
-
34
-
-
0035947226
-
A comparison of the induction of immortalized endothelial cell impermeability by astrocytes
-
Tan KH, Dobbie MS, Felix RA, Barrand MA, Hurst RD. 2001. A comparison of the induction of immortalized endothelial cell impermeability by astrocytes. NeuroReport 12:1329-1334.
-
(2001)
NeuroReport
, vol.12
, pp. 1329-1334
-
-
Tan, K.H.1
Dobbie, M.S.2
Felix, R.A.3
Barrand, M.A.4
Hurst, R.D.5
-
35
-
-
0033673170
-
Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes
-
Gaillard PJ, Voorwinden LH, Nielsen JL, Ivanov A, Atsumin R, Engman H, Ringbom C, de Boer AG, Breimer DD. 2001. Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes. Eur J Pharm Sci 12:215-222.
-
(2001)
Eur J Pharm Sci
, vol.12
, pp. 215-222
-
-
Gaillard, P.J.1
Voorwinden, L.H.2
Nielsen, J.L.3
Ivanov, A.4
Atsumin, R.5
Engman, H.6
Ringbom, C.7
de Boer, A.G.8
Breimer, D.D.9
-
36
-
-
0025319983
-
Brain edema and cerebrovascular permeability during cerebral ischemia in rats
-
Hatashita S, Hoff JT. 1990. Brain edema and cerebrovascular permeability during cerebral ischemia in rats. Stroke 21:582-588.
-
(1990)
Stroke
, vol.21
, pp. 582-588
-
-
Hatashita, S.1
Hoff, J.T.2
-
37
-
-
0028203549
-
Electron microscopy of the blood-brain barrier in disease
-
Hirano A, Kawanami T, Llena J. 1994. Electron microscopy of the blood-brain barrier in disease. Microsc Res Tech 27:543-556.
-
(1994)
Microsc Res Tech
, vol.27
, pp. 543-556
-
-
Hirano, A.1
Kawanami, T.2
Llena, J.3
-
38
-
-
0028128974
-
Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats
-
Yang G, Betz AL. 1994. Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats. Stroke 25:1658-1664.
-
(1994)
Stroke
, vol.25
, pp. 1658-1664
-
-
Yang, G.1
Betz, A.L.2
-
39
-
-
0028246186
-
Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes
-
Wolburg H, Neuhaus J, Kniesel U, Krauss B, Schimid EM, Ocalan M, Farrell C, Risau W. 1994. Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J Cell Sci 107:1347-1357.
-
(1994)
J Cell Sci
, vol.107
, pp. 1347-1357
-
-
Wolburg, H.1
Neuhaus, J.2
Kniesel, U.3
Krauss, B.4
Schimid, E.M.5
Ocalan, M.6
Farrell, C.7
Risau, W.8
-
40
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese TS, Karnovsky MJ. 1967. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J cell Biol 34:207-217.
-
(1967)
J cell Biol
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
41
-
-
7044260589
-
Effects of hypoxia on endothelial/pericytic co-culture model of the blood-brain barrier
-
Hayashi K, Nakao S, Nakaoke R, Nakagawa S, Kitagawa N, Niwa M. 2004. Effects of hypoxia on endothelial/pericytic co-culture model of the blood-brain barrier. Regul Pept 123:77-83.
-
(2004)
Regul Pept
, vol.123
, pp. 77-83
-
-
Hayashi, K.1
Nakao, S.2
Nakaoke, R.3
Nakagawa, S.4
Kitagawa, N.5
Niwa, M.6
-
42
-
-
9944256233
-
The use of human nasal in vitro cell systems during drug discovery and development
-
Dimova S, Brewster ME, Noppe M, Jorissen M, Augustijins P. 2005. The use of human nasal in vitro cell systems during drug discovery and development. Toxicol In Vitro 19:107-122.
-
(2005)
Toxicol In Vitro
, vol.19
, pp. 107-122
-
-
Dimova, S.1
Brewster, M.E.2
Noppe, M.3
Jorissen, M.4
Augustijins, P.5
-
43
-
-
0031049535
-
Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide
-
Pal D, Audus KL, Siahaan TJ. 1997. Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide. Brain Res 747:103-113.
-
(1997)
Brain Res
, vol.747
, pp. 103-113
-
-
Pal, D.1
Audus, K.L.2
Siahaan, T.J.3
-
45
-
-
0032936851
-
The cell biology of the blood-brain barrier
-
Rubin LL, Staddon JM. 1999. The cell biology of the blood-brain barrier. Ann Rev Neurosci 22:11-28.
-
(1999)
Ann Rev Neurosci
, vol.22
, pp. 11-28
-
-
Rubin, L.L.1
Staddon, J.M.2
-
46
-
-
0021794208
-
The blood-brain barrier, a dynamic regulatory interface
-
Cornford EM. 1985. The blood-brain barrier, a dynamic regulatory interface. Mol Physiol 7:219-259.
-
(1985)
Mol Physiol
, vol.7
, pp. 219-259
-
-
Cornford, E.M.1
-
47
-
-
0026451081
-
Interacellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Nishizuka Y. 1992. Interacellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614.
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
48
-
-
1542778866
-
Signaling pathways regulation the tight junction permeability in the blood-brain barrier
-
Krizbai IA, Deli MA. 2003. Signaling pathways regulation the tight junction permeability in the blood-brain barrier. Cell Mol Biol 49:23-31.
-
(2003)
Cell Mol Biol
, vol.49
, pp. 23-31
-
-
Krizbai, I.A.1
Deli, M.A.2
-
49
-
-
27144446361
-
-
Fleegal MA, Hom S, Borg LK, Davis TP. 2005. Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxygenation. Am J Physiol Heart Circ Physiol 289:H2012-H2019.
-
Fleegal MA, Hom S, Borg LK, Davis TP. 2005. Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxygenation. Am J Physiol Heart Circ Physiol 289:H2012-H2019.
-
-
-
|