Graded reversible opening of the rat blood-brain barrier by intracarotid infusion of sodium caprate

Journal of Neuroscience Methods

Volumn 168, Issue 2, 2008, Pages 443-449

  Preston, Edward ^a   Slinn, Jacqueline ^a   Vinokourov, Inna ^a   Stanimirovic, Danica ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Blood brain barrier; Cerebral vasculature; CNS drug delivery; Endothelial cells; Sodium caprate; Tight junctions

Indexed keywords

CARBON 14; DECANOATE SODIUM; DECANOIC ACID DERIVATIVE; INULIN; INULIN C 14; MANNITOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD PRESSURE REGULATION; BRAIN BLOOD VESSEL; BRAIN EDEMA; CARDIOPULMONARY INSUFFICIENCY; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; EPITHELIUM CELL; HYPOTENSION; HYPOVOLEMIA; INTERNAL CAROTID ARTERY; INTESTINE ABSORPTION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; TIGHT JUNCTION;

ANIMALS; BLOOD PRESSURE; BLOOD-BRAIN BARRIER; CAROTID ARTERIES; DECANOIC ACIDS; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOVOLEMIA; INFUSIONS, INTRA-ARTERIAL; INULIN; MALE; MANNITOL; RATS; RATS, SPRAGUE-DAWLEY; TIGHT JUNCTIONS;

EID: 39049159204     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2007.11.004     Document Type: Article

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