RNAi mediated silencing of ATPase RNA helicase gene in adult filarial parasite Brugia malayi impairs in vitro microfilaria release and adult parasite viability

Journal of Biotechnology

Volumn 157, Issue 3, 2012, Pages 351-358

  Singh, Meghna ^a   Singh, Prashant Kumar ^a   Misra Bhattacharya, Shailja ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

B. malayi; Drug target; Embryogenesis; Filaria; RNA helicase; RNAi

Indexed keywords

B. MALAYI; DRUG TARGETS; EMBRYOGENESIS; FILARIA; RNA HELICASE; RNAI;

ENZYMES; GENES; POLYMERASE CHAIN REACTION; RNA;

TRANSCRIPTION;

ADENOSINE TRIPHOSPHATASE; ANTIFILARIAL AGENT; DEAD BOX PROTEIN; RNA HELICASE;

ARTICLE; BRUGIA MALAYI; ELECTROPORATION; FEMALE; GENE EXPRESSION; GENE SILENCING; IN VITRO STUDY; MALE; MICROFILARIA; NONHUMAN; PARASITE VIABILITY; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SYNTHESIS;

ADENOSINE TRIPHOSPHATASES; ANALYSIS OF VARIANCE; ANIMALS; DNA PRIMERS; ELECTROPORATION; FEMALE; GENE KNOCKDOWN TECHNIQUES; MALE; MICROFILARIA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA HELICASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPIRURIDA; TETRAZOLIUM SALTS; THIAZOLES;

BRUGIA MALAYI; FILARIA;

EID: 84856743209     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2011.12.003     Document Type: Article

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