LyP-1 modification to enhance delivery of Artemisinin or fluorescent probe loaded polymeric micelles to highly metastatic tumor and its lymphatics

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2646-2657

  Wang, Zhaohui ^a   Yu, Yang ^a   Ma, Jie ^b   Zhang, Haoran ^a   Zhang, Hua ^a   Wang, Xueqing ^a   Wang, Jiancheng ^a   Zhang, Xuan ^a   Zhang, Qiang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

artemisinin; highly metastatic breast cancer; polymeric micelles; specific delivery; tumor lymphatics

Indexed keywords

ARTEMISININ; FLUORESCENT DYE; LYMPHATICS HOMING PEPTIDE 1; PEPTIDE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTILYMPHANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLOOD VESSEL; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE; CELL TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DISTRIBUTION; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; LYMPH VESSEL; LYMPHATIC ENDOTHELIAL CELL; METASTASIS; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARTEMISININS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; FEMALE; FLUORESCENT DYES; HUMANS; KINETICS; LYMPHATIC SYSTEM; MICE; MICE, INBRED BALB C; MICE, NUDE; MICELLES; PEPTIDES, CYCLIC; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS;

EID: 84865955591     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3002107     Document Type: Article

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